Pyridines and derivatives
- (4)
- (1)
- (5)
- (5)
- (520)
- (22)
- (2,105)
- (22)
- (2)
- (5)
- (5)
- (271)
- (175)
- (1)
- (14)
- (50)
- (300)
- (86)
- (225)
- (6)
- (4)
- (2)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (5)
- (1)
- (12)
- (4)
- (8)
- (7)
- (12)
- (60)
- (867)
- (5)
- (55)
- (60)
- (58)
- (19)
- (346)
- (2)
- (4)
- (2)
- (1)
- (1)
- (5)
- (275)
- (1)
- (1,700)
- (2)
- (27)
- (7)
- (1)
- (92)
- (4)
- (13)
- (77)
- (128)
- (54)
- (59)
- (2)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (5)
- (2)
- (1)
- (1)
- (2)
- (1)
- (2)
- (2)
- (3)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (9)
- (4)
- (1)
- (2)
- (4)
- (2)
- (1)
- (5)
- (17)
- (23)
- (1)
- (1)
- (60)
- (21)
- (1)
- (1)
- (29)
- (49)
- (7)
- (2)
- (1)
- (5)
- (6)
- (12)
- (1)
- (1)
- (1)
- (18)
- (1)
- (14)
- (4)
- (1)
- (11)
- (5)
- (1)
- (10)
- (15)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (9)
- (7)
- (1)
- (2)
- (1)
- (4)
- (6)
- (2)
- (1)
- (1)
- (1)
- (4)
- (4)
- (1)
- (1)
- (5)
- (15)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (12)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (15)
- (17)
- (4)
- (2)
- (2)
- (5)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (7)
- (5)
- (9)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (1)
- (16)
- (7)
- (5)
- (1)
- (1)
- (3)
- (5)
- (10)
- (2)
- (1)
- (6)
- (6)
- (7)
- (12)
- (1)
- (1)
- (39)
- (1)
- (12)
- (11)
- (4)
- (2)
- (2)
- (15)
- (15)
- (1)
- (1)
- (1)
- (2)
- (9)
- (3)
- (2)
- (1)
- (1)
- (3)
- (6)
- (3)
- (3)
- (1)
- (3)
- (1)
- (1)
- (1)
- (3)
- (3)
- (1)
- (6)
- (5)
- (2)
- (1)
- (19)
- (9)
- (1)
- (2)
- (1)
- (1)
- (1)
- (22)
- (22)
- (2)
- (2)
- (1)
- (1)
- (2)
- (2)
- (22)
- (16)
- (6)
- (2)
- (1)
- (1)
- (2)
- (7)
- (2)
- (3)
- (1)
- (1)
- (2)
- (1)
- (8)
- (17)
- (2)
- (1)
- (6)
- (1)
- (3)
- (1)
- (2)
- (1)
- (6)
- (2)
- (4)
- (2)
- (1)
- (1)
- (1)
- (6)
- (2)
- (3)
- (3)
- (3)
- (5)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (6)
- (1)
- (1)
- (2)
- (5)
- (3)
- (1)
- (4)
- (12)
- (48)
- (1)
- (4)
- (2)
- (3)
- (1)
- (2)
- (1)
- (1)
- (7)
- (9)
- (22)
- (30)
- (1)
- (1)
- (3)
- (2)
- (2)
- (4)
- (11)
- (5)
- (1)
- (1)
- (55)
- (6)
- (1)
- (7)
- (2)
- (1)
- (1)
- (1)
- (2)
- (2)
- (4)
- (1)
- (1)
- (1)
- (1)
- (2)
- (6)
- (4)
- (15)
- (5)
- (2)
- (1)
- (1)
- (1)
- (1)
- (3)
- (10)
- (1)
- (17)
- (9)
- (1)
- (1)
- (2)
- (4)
- (4)
- (1)
- (1)
- (1)
- (1)
- (2)
- (3)
- (11)
- (13)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (10)
- (23)
- (1)
- (16)
- (2)
- (2)
- (1)
- (1)
- (2)
- (6)
- (3)
- (1)
- (1)
- (7)
- (11)
- (3)
- (2)
- (1)
- (1)
- (2)
- (4)
- (5)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (34)
- (3)
- (4)
- (4)
- (3)
- (1)
- (2)
- (1)
- (1)
- (2)
- (2)
- (5)
- (3)
- (5)
- (8)
- (4)
- (2)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (2)
- (4)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (10)
- (2)
- (17)
- (1)
- (13)
- (2)
- (3)
- (1)
- (5)
- (18)
- (1)
- (13)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (18)
- (11)
- (18)
- (1)
- (1)
- (3)
- (1)
- (17)
- (8)
- (6)
- (2)
- (2)
- (2)
- (2)
- (1)
- (4)
- (4)
- (1)
- (3)
- (2)
- (7)
- (11)
- (2)
- (2)
- (2)
- (4)
- (1)
- (8)
- (5)
- (6)
- (24)
- (2)
- (1)
- (2)
- (6)
- (1)
- (4)
- (1)
- (1)
- (2)
- (2)
- (1)
- (2)
- (9)
- (12)
- (1)
- (12)
- (26)
- (8)
- (1)
- (1)
- (1)
- (7)
- (9)
- (1)
- (1)
- (1)
- (3)
- (1)
- (15)
- (5)
- (2)
- (2)
- (3)
- (4)
- (2)
- (1)
- (5)
- (3)
- (1)
- (2)
- (1)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (8)
- (6)
- (1)
- (2)
- (2)
- (7)
- (1)
- (1)
- (11)
- (8)
- (1)
- (3)
- (4)
- (1)
- (2)
- (6)
- (6)
- (2)
- (1)
- (1)
- (1)
- (2)
- (3)
- (2)
- (1)
- (2)
- (1)
- (1)
- (3)
- (2)
- (1)
- (2)
- (2)
- (1)
- (3)
- (6)
- (1)
- (5)
- (27)
- (2)
- (15)
- (4)
- (3)
- (9)
- (4)
- (4)
- (18)
- (8)
- (2)
- (4)
- (7)
- (1)
- (32)
- (2)
- (75)
- (1)
- (4)
- (53)
- (1)
- (3)
- (1)
- (10)
- (6)
- (33)
- (6)
- (1)
- (1)
- (106)
- (1)
- (9)
- (544)
- (5)
- (462)
- (42)
- (22)
- (130)
- (9)
- (1)
- (117)
- (1)
- (2)
- (3)
- (1)
- (1)
- (27)
- (32)
- (15)
- (4)
- (13)
- (12)
- (1)
- (2)
- (2)
- (13)
- (1)
- (2)
- (2)
- (1)
- (2)
- (20)
- (1)
- (1)
- (1)
- (1)
- (27)
- (6)
- (1)
- (1)
- (4)
- (5)
- (4)
- (5)
- (3)
- (1)
- (3)
- (1)
- (47)
- (1)
- (11)
- (364)
- (5)
- (3)
- (133)
- (1,015)
- (4)
- (2)
- (1)
- (3)
- (12)
- (904)
- (7)
- (35)
- (7)
- (2)
- (1)
- (418)
- (26)
- (4)
- (10)
- (1)
- (1)
- (4)
- (1)
- (2)
- (6)
- (2)
- (4)
- (1)
- (4)
- (1)
- (3)
- (19)
- (2)
- (8)
- (72)
- (4)
- (1,561)
- (2)
- (4)
- (12)
- (9)
- (1)
- (14)
- (3)
- (9)
- (3)
- (2)
- (5)
- (4)
- (2)
- (1)
- (16)
- (3)
- (13)
- (11)
- (13)
- (10)
- (2)
- (2)
- (1)
- (2)
- (2)
- (408)
- (5)
- (6)
- (2)
- (7)
- (2)
- (3)
- (2)
- (237)
- (3)
- (2)
- (3)
- (18)
- (5)
- (2)
- (264)
- (3)
- (4)
- (4)
- (1)
- (2)
- (1)
- (4)
- (1)
- (2)
- (2)
- (2)
- (5)
- (2)
- (3)
- (9)
- (2)
- (2)
- (2)
- (2)
- (2)
- (7)
- (1)
- (1)
- (2)
- (2)
- (8)
- (3)
- (2)
- (2)
- (5)
- (4)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (2)
- (2)
- (3)
- (1)
- (1)
- (3)
- (3)
- (1)
- (2)
- (3)
- (13)
- (1)
- (2)
- (1)
- (4)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (1)
- (9)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (4)
- (1)
- (1)
- (1)
- (1)
- (2)
- (10)
- (1)
- (2)
- (1)
- (1)
- (3)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (4)
- (2)
- (2)
- (5)
- (1)
- (2)
- (4)
- (2)
- (1)
- (2)
- (1)
- (2)
- (1)
- (2)
- (1)
- (2)
- (3)
- (3)
- (4)
- (2)
- (1)
- (3)
- (3)
- (2)
- (3)
- (1)
- (1)
- (5)
- (1)
- (3)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (4)
- (1)
- (1)
- (3)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (4)
- (1)
- (1)
- (1)
- (1)
- (1)
- (5)
- (1)
- (2)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (3)
- (1)
- (1)
- (3)
- (6)
- (1)
- (4)
- (1)
- (2)
- (2)
- (1)
- (1)
- (2)
- (3)
- (1)
- (4)
- (3)
- (6)
- (3)
- (1)
- (9)
- (1)
- (2)
- (2)
- (2)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (6)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (3)
- (3)
- (1)
- (1)
- (2)
- (1)
- (3)
- (2)
- (1)
- (2)
- (1)
- (2)
- (6)
- (2)
- (1)
- (1)
- (3)
- (9)
- (2)
- (1)
- (2)
- (1)
- (3)
- (1)
- (2)
- (1)
- (2)
- (3)
- (2)
- (6)
- (1)
- (1)
- (3)
- (1)
- (1)
- (1)
- (1)
- (3)
- (3)
- (2)
- (2)
- (1)
- (1)
- (1)
- (2)
- (3)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (3)
- (2)
- (2)
- (2)
- (2)
- (1)
- (2)
- (5)
- (1)
- (2)
- (2)
- (3)
- (1)
- (3)
- (2)
- (3)
- (9)
- (4)
- (1)
- (4)
- (4)
- (1)
- (2)
- (3)
- (4)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (7)
- (3)
- (2)
- (1)
- (2)
- (2)
- (5)
- (3)
- (1)
- (1)
- (3)
- (2)
- (1)
- (3)
- (1)
- (2)
- (3)
- (1)
- (3)
- (1)
- (1)
- (1)
- (2)
- (1)
- (4)
- (2)
- (5)
- (1)
- (3)
- (3)
- (2)
- (5)
- (2)
- (1)
- (4)
- (3)
- (3)
- (2)
- (2)
- (3)
- (3)
- (2)
- (1)
- (1)
- (2)
- (3)
- (2)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (4)
- (1)
- (3)
- (3)
- (2)
- (1)
- (4)
- (1)
- (1)
- (4)
- (4)
- (1)
- (4)
- (3)
- (6)
- (2)
- (2)
- (3)
- (1)
- (1)
- (3)
- (1)
- (2)
- (1)
- (1)
- (6)
- (3)
- (1)
- (5)
- (3)
- (4)
- (2)
- (1)
- (2)
- (1)
- (2)
- (2)
- (2)
- (3)
- (1)
- (2)
- (1)
- (1)
- (2)
- (2)
- (4)
- (2)
- (1)
- (2)
- (2)
- (1)
- (2)
- (2)
- (2)
- (3)
- (4)
- (5)
- (2)
- (2)
- (2)
- (3)
- (2)
- (1)
- (3)
- (3)
- (3)
- (2)
- (2)
- (2)
- (1)
- (2)
- (6)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (4)
- (1)
- (1)
- (5)
- (3)
- (5)
- (2)
- (4)
- (4)
- (2)
- (3)
- (1)
- (1)
- (1)
- (2)
- (4)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (2)
- (7)
- (1)
- (3)
- (3)
- (4)
- (3)
- (3)
- (5)
- (6)
- (2)
- (2)
- (2)
- (1)
- (4)
- (2)
- (1)
- (3)
- (2)
- (1)
- (1)
- (4)
- (7)
- (1)
- (2)
- (2)
- (2)
- (2)
- (2)
- (1)
- (3)
- (3)
- (3)
- (4)
- (2)
- (3)
- (2)
- (2)
- (3)
- (2)
- (3)
- (1)
- (1)
- (2)
- (5)
- (1)
- (4)
- (2)
- (2)
- (1)
- (1)
- (3)
- (1)
- (6)
- (1)
- (1)
Filtered Search Results
Medchemexpress LLC GlyRS-IN-1 | 112921-11-6 | 99.4% | 403.37 | 1 ML
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
GlyRS-IN-1 is a glycyl-tRNA synthase (GlyRS) inhibitor extracted from patent WO 2017066459 A1. It can also inhibit the growth of bacteria. It is for research use only and not sold to patients.
- Acts as a GlyRS inhibitor
- Inhibits the growth of bacteria
- For research use only
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC SMANT hydrochloride | 1177600-74-6 | 99.9% | 375.73 | 10 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
SMANT hydrochloride is a Smoothened (Smo) signaling inhibitor. It acts as an antagonist of Smo accumulation within the primary cilium (PC). This compound demonstrates equivalent activity in inhibiting both the oncogenic form of Smo (SmoM2) and wild-type Smo.
- For research use only.
- Inhibits Hh induced Smo accumulation at the primary cilium with an IC50 of 1.1 μM.
- Blocks the stimulatory action of SAG in Gli-luciferase assay.
- Inhibits proliferation of cerebellar granule-cell neural progenitors induced by Shh.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC IKK 16 | 873225-46-8 | 99.9% | 483.63 | 1 ML
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
IKK 16 is an orally active inhibitor targeting IKK, PKD, and ABCB1 pathways. It demonstrates potent inhibitory activity against IKK2, IKK complex, IKK1, and LRRK2, as well as PKD1, PKD2, and PKD3. This compound offers protective effects against LPS-induced organ dysfunction, supports renal function recovery, and helps reduce fibrosis in acute kidney injury. It also attenuates cardiac dysfunction in models of polymicrobial sepsis with type 2 diabetes mellitus by modulating the NF-κB pathway.
- Orally active IKK inhibitor
- Functions as a pan-PKD inhibitor
- Inhibits ABCB1, interfering with substrate binding
- Protects against LPS-induced multiple organ dysfunction
- Restores renal function and alleviates fibrosis in acute kidney injury
- Attenuates cardiac dysfunction in polymicrobial sepsis models
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC Roniciclib | 1223498-69-8 | 98.0% | 430.44 | 25 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Roniciclib is an orally bioavailable pan-cyclin dependent kinase (CDK) inhibitor. It has IC50s of 5-25 nM for CDK1, CDK2, CDK3, CDK4, CDK7, and CDK9.
- Inhibits the kinase activity of cell-cycle CDKs (CDK1/cyclin B, CDK2/cyclin E, and CDK4/cyclin D)
- Inhibits transcriptional CDKs (CDK9/cyclin T1 and CDK7/cyclin H/MAT1)
- Potently inhibits the proliferation of various human and murine tumor cell lines
- Strongly inhibits tumor growth in a dose-dependent manner
- Low blood clearance rates in mouse, rat, and dog
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Apexbio Technology LLC UNC3866 1872382-47-2 25mg
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
UNC3866 (CAS 1872382-47-2) is a potent selective antagonist of the chromodomains in CBX4 and CBX7 exhibiting Kd values near 100 nM and 97 nM respectively Its affinity for these targets is markedly higher by 6- to 18-fold compared to other CBX and CDY chromodomains UNC3866 competitively blocks methyl-lysine recognition by Polycomb CBX and CDY family proteins as demonstrated by disruption of the CBX7-H3 interaction in AlphaScreen assays (IC50 66 nM) The compound s selectivity correlates with sequence homology and structural complementarity as shown by x-ray crystallography UNC3866 inhibits PC3 cell proliferation and serves as a chemical probe for studying chromodomain-mediated gene regulation and chromatin biology
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Selleck Chemical LLC GSK0660
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
GSK0660 is a potent PPAR / antagonist with a pIC50 of 6 8 (binding assay IC50 155 nM antagonist assay IC50 300 nM) and is nearly inactive on PPAR and PPAR with IC50s above approximately 10 M
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Ambeed 4S 4 S 2 2 2Phenyl1 phenylme
(4S,4'S)-2,2'-[2Phenyl-1-(phenylmethyl)ethylidene]bis[4,5-dihydro-4-phenyl-Oxazole, 319489-87-7, 98% 99%ee
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC IZUMO1 Human HEK29 50ug | 50ug
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
IZUMO1 Protein Human (HEK293 His) is the recombinant human-derived IZUMO1 expressed by HEK293 with C-6 His labeled tag
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC Clec11a/SCGF-alpha protein, rat (HEK293, His) | ≥90.0% | 100UG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Recombinant, glycosylated rat CLEC11A (SCGF-alpha) produced in HEK293 cells with a C-terminal His tag, supplied as a sterile PBS solution for research applications.
- Glycosylated protein with apparent molecular weight approximately 45-60 kDa.
- Purity ≥90% by reducing SDS-PAGE.
- Supplied in PBS, pH 7.4, 0.22 μm filtered solution at 0.57 mg/mL.
- Contains a C-terminal His tag for detection and purification.
- Recommended storage at -80°C; avoid repeated freeze-thaw cycles.
- Suitable for in vitro biochemical and cell-based assays.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC LIF Human HEK293 20ug
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
LIF protein induces terminal differentiation in leukemic cells promoting hematopoietic and neuronal cell differentiation and stimulating acute-phase protein synthesis in hepatocytes Its diverse activities highlight its role in influencing cellular differentiation across various cell types and physiological contexts LIF Protein Human (HEK293) is the recombinant human-derived LIF protein expressed by HEK293 with tag free
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC Scn3b protein, human (HEK293, C-terminal His-tag) | >95.0% | 5 UG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Recombinant human SCN3B protein expressed in HEK293 cells with a C-terminal 6xHis tag. Supplied as a purified protein (commonly available in 5 μg vials) for research use in studies of sodium channel function, trafficking, and protein-protein interactions. Purity >95% by reducing SDS-PAGE; observed molecular weight ~23-34 kDa due to glycosylation.
- Expression system: HEK293 cells.
- C-terminal 6xHis tag for detection and purification.
- Purity greater than 95% by reducing SDS-PAGE.
- Glycosylated molecular weight approximately 23-34 kDa.
- Suitable for electrophysiology and biochemical interaction studies.
- Supplied in small research-scale quantities (e.g., 5 μg).
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC Sevasemten (EDG-5506) | 2417395-15-2 | 99.3% | 381.28 | 5 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Sevasemten is an orally active, selective allosteric inhibitor of skeletal muscle myosin. It protects skeletal muscle from contraction-induced injury, reduces muscle damage biomarkers and fibrosis, and increases muscle strength and activity in Duchenne muscular dystrophy disease models.
- Orally active, selective allosteric inhibitor of skeletal muscle myosin
- Protects skeletal muscle from contraction-induced injury
- Decreases muscle damage biomarkers and fibrosis
- Increases muscle strength and activity in Duchenne muscular dystrophy disease models
- Reduces the force of fast skeletal muscle fibers
- Inhibits fast myofibril ATPase
- Protects muscles from contraction damage
- Ameliorates Duchenne muscular dystrophy in animal models
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC Endothelial protein C receptor (EPCR) | >95.0% | 100 UG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Recombinant rat endothelial protein C receptor (EPCR) expressed in HEK293 cells with a C-terminal 6xHis tag. Supplied lyophilized for research use, the protein is provided with purity and formulation data and recommended storage instructions for biochemical and receptor-binding assays.
- Expressed in HEK293 cells for mammalian post-translational modifications.
- Contains a C-terminal 6xHis tag to facilitate purification.
- Purity greater than 95% as determined by reducing SDS-PAGE.
- Lyophilized from 0.22 μm filtered PBS, pH 7.4, for stability during storage and transport.
- Sequence accession Q4V8I1, covering residues N21-S213.
- For research use only; not for human therapeutic or diagnostic use.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC Gossypolone | 4547-72-2 | 96.3% | 1 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Gossypolone is a small-molecule inhibitor of the RNA-binding protein Musashi-1 used for preclinical and research applications, particularly in cancer research. Supplied as a light yellow to brown solid with stated purity of about 96.3%, it is intended for laboratory research use only and should be stored under nitrogen at 4°C; in solution, store at -80°C (up to 6 months) or -20°C (up to 1 month).
- Small-molecule inhibitor of Musashi-1 (MSI1)
- CAS number 4547-72-2
- Molecular formula C30H26O10, molecular weight 546.52 g/mol
- Purity 96.3%
- Appearance: light yellow to brown solid
- Intended for laboratory research use only
- Recommended storage: under nitrogen at 4°C; in solution, -80°C (6 months) or -20°C (1 month)
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC 2,6-dichloro-N-(2,6-dimethylphenyl)hexanamide | 1037184-07-8 | MFCD25562938 | >98.0% | 288.21 g/mol | C14H19Cl2NO | 5 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
2,6-Dichloro-N-(2,6-dimethylphenyl)hexanamide is an amide impurity associated with the local anesthetic bupivacaine. Supplied for research and analytical use in small milligram quantities, the substance is used as an impurity reference standard and for method development and quality control in laboratories.
- CAS number: 1037184-07-8
- Chemical formula: C14H19Cl2NO
- Molecular weight: 288.21 g/mol
- Purity: >98.0%
- Typical pack size: 5 mg for research applications
- Common use: impurity reference for analytical and method development
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More