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- (1)
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Medchemexpress LLC TRAT1 HUMAN HIS 50UG
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5000196839 TRAT1 HUMAN HIS 50UG
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![Medchemexpress LLC 2-Propenamide, N-[3-[4-[[(1S)-2-hydroxy-1-phenylethyl]amino]-6-phenylfuro[2,3-d]pyrimidin-5-yl... | 1226549-39-8 | >98.8% | 476.53 | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000387648-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 2-Propenamide, N-[3-[4-[[(1S)-2-hydroxy-1-phenylethyl]amino]-6-phenylfuro[2,3-d]pyrimidin-5-yl... | 1226549-39-8 | >98.8% | 476.53 | 1 ML
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EGFR-IN-9 (Compound 8) is a potent EGFR kinase inhibitor with IC50s of 7 nM for wild-type EGFR kinase and 28 nM for the double mutant EGFR kinase (L858R/T790M). It exhibits antitumor activity.
- Potent EGFR kinase inhibitor.
- IC50 of 7 nM for wild-type EGFR.
- IC50 of 28 nM for double mutant EGFR kinase (L858R/T790M).
- Exhibits antitumor activity.
- Antiproliferative activity in HCC827 lung cancer cell line with an IC50 of 8 nM.
- Appears as a solid, off-white to light yellow color.
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Medchemexpress LLC WIF-1 HUMAN HEK293 500UG
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5000196876 WIF-1 HUMAN HEK293 500UG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000399192 IL-31R ALPHA CYNOMO 50UG
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![Medchemexpress LLC 5-fluoro-2-[(Z)-(2-hexahydropyridazin-1-yl-4-oxo-thiazol-5-ylidene)methyl]phenyl pyrrolidine-1-carboxylate | 1181083-81-7 | ≥98.0% | 404.46 g/mol | C19H21FN4O3S | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000247511.png-250.jpg)
Medchemexpress LLC 5-fluoro-2-[(Z)-(2-hexahydropyridazin-1-yl-4-oxo-thiazol-5-ylidene)methyl]phenyl pyrrolidine-1-carboxylate | 1181083-81-7 | ≥98.0% | 404.46 g/mol | C19H21FN4O3S | 1 ML
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CLP290 is a small-molecule activator of the neuron-specific K+-Cl- cotransporter KCC2 used in neuroscience research. It is provided as a 10 mM solution in DMSO for laboratory use.
- Small-molecule activator of the neuron-specific K+-Cl- cotransporter KCC2.
- Used for neuroscience research exploring neuronal inhibition and pain models.
- Supplied as a 10 mM solution in DMSO, 1 mL.
- Molecular formula C19H21FN4O3S; molecular weight 404.46 g/mol.
- Purity ≥98.0% (HPLC).
- For research use only; not for human or clinical use.
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Medchemexpress LLC Amenamevir | 841301-32-4 | 99.9% | 482.55 | 25 MG
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Amenamevir is a potent helicase-primase inhibitor with significant antiviral activity against Herpes Simplex Viruses (HSVs). It effectively inhibits the replication of HSV-1 and HSV-2 strains, demonstrating lower EC50 values compared to acyclovir in both in vitro and in vivo models. This compound is suitable for various laboratory research applications.
- Potent helicase-primase inhibitor
- Exhibits antiviral activity against HSVs
- Inhibits HSV-1 and HSV-2 replication
- Demonstrates lower EC50 values compared to acyclovir
- Suitable for in vitro and in vivo research applications
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Medchemexpress LLC Cadherin-1/CD324 Hu 5ug | 5ug
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Cadherin-1/CD324 Protein Human (HEK293 His) is a recombinant human E-cadherin produced in HEK293 cells with His tag Cadherin-1/CD324/E-cadherin is one of the most important molecules in cell-cell adhesion in epithelial tissues[1]
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Medchemexpress LLC MUELLERIAN-INHIBITIN 10UG
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5000196242 MUELLERIAN-INHIBITIN 10UG
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Medchemexpress LLC DAPK3/ZIPK Human s 50ug | 50ug
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The DAPK3/ZIPK protein is a multifunctional serine/threonine kinase that complexly regulates apoptosis autophagy transcription translation and actin cytoskeletal reorganization Its key roles include coordinating apoptotic and autophagy signaling influencing smooth muscle contraction and regulating starvation-induced autophagy DAPK3/ZIPK Protein Human (sf9 GST) is the recombinant human-derived DAPK3/ZIPK protein expressed by Sf9 insect cells with N-GST labeled tag
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Medchemexpress LLC TREM-2 MOUSE HEK29 5UG
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5000197349 TREM-2 MOUSE HEK29 5UG
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Medchemexpress LLC SF20/MYDGF Mouse 2ug
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SF20/MYDGF protein promotes cardiac myocyte survival and adaptive angiogenesis after myocardial infarction (MI) It stimulates endothelial cell proliferation via MAPK1/3 STAT3 and CCND1 signaling and inhibits cardiac myocyte apoptosis through PI3K/AKT signaling Given its ability to enhance cardiac function and angiogenesis SF20/MYDGF protein could be a valuable therapeutic target for improving outcomes in MI patients SF20/MYDGF Protein Mouse is the recombinant mouse-derived SF20/MYDGF expressed by E coli with tag-free
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Medchemexpress LLC TIM-3/HAVCR2 Cynomo 50ug
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The TIM-3/HAVCR2 protein is a cell surface receptor that regulates immune responses by inhibiting macrophage activation and suppressing Th1-mediated autoimmunity TIM-3/HAVCR2 Protein Cynomolgus (HEK293 His) is the recombinant cynomolgus-derived TIM-3/HAVCR2 protein expressed by HEK293 with N-8 His labeled tag
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Medchemexpress LLC Metergoline | 17692-51-2 | 99.9% | 5 MG
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Metergoline is a serotonin (5-HT) receptor and dopamine receptors antagonist. Its pKis are 8.64, 8.75, and 8.75 for 5-HT2A, 5-HT2B, and 5-HT2C, respectively. It is also a high-affinity ligand for the h5-HT7 receptor, with a Ki of 16 nM. Additionally, Metergoline acts as a reversible neural Na+ channels inhibitor. It is commonly used in research for seasonal affective disorder and prolactin hormone regulation.
- Serotonin (5-HT) receptor and dopamine receptor antagonist
- High-affinity ligand for the h5-HT7 receptor (Ki = 16 nM)
- Reversible neural Na+ channels inhibitor
- Used in research for seasonal affective disorder and prolactin hormone regulation
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Medchemexpress LLC Dalutrafusp alfa 5mg | 5mg
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Dalutrafusp alfa (AGEN-1423 GS-1423) is a specific bifunctional antibody against CD73 and TGF- which is involved in the immunosuppressive pathway[1]
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BIOHIPPO IGF1A-V5/GFP
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IGF1A-V5/GFP lentiviral vector expressing V5 under CMV promoter Each vial provides a nominal titer of 2x10E6 transducing units TU Human insulin like growth factor 1 (IGF1A) ORF cDNA lentivirus Lentiviral particles packaged with expression vector for human IGF1A (also known as IGF-1 somatomedin-C) transcript variant 4 A CMV promoter drives expression of IGF1A fused to a C-terminal V5 tag and an RFP reporter which is separated from the ORF cDNA by a self-cleaving peptide These lentiviral particles allow for easy transduction and high stable expression of the indicated ORF cDNA in mammalian cells The lentiviral vectors have been optimized to provide high gene expression and reliable genome integration allowing for easy establishment of long-term stable cell lines with consistent read out of fluorescent (GFP RFP) or luminescent (firefly luc) reporters
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