Pyridines and derivatives
4-Bromo-2-chloropyridine, 94%
CAS: 73583-37-6 Molecular Formula: C5H3BrClN Molecular Weight (g/mol): 192.44 MDL Number: MFCD03840756 InChI Key: ONHMWUXYIFULDO-UHFFFAOYSA-N Synonym: 2-chloro-4-bromopyridine,pyridine, 4-bromo-2-chloro,4-bromo-2-chloro-pyridine,pubchem1171,acmc-1bjmw,ksc381c4t,tpc-py061,4-bromo-2-chloropyridine,abbypharma ap-18-5387,4-bromo-2-chloropyridine 5g PubChem CID: 3847770 IUPAC Name: 4-bromo-2-chloropyridine SMILES: C1=CN=C(C=C1Br)Cl
2,3,5-Trichloropyridine 98.0+%, TCI America™
CAS: 16063-70-0 Molecular Formula: C5H2Cl3N Molecular Weight (g/mol): 182.428 MDL Number: MFCD00043007 InChI Key: CNLIIAKAAMFCJG-UHFFFAOYSA-N Synonym: pyridine, 2,3,5-trichloro,2,3,5-trichloro pyridine,2,3,5-trichloro-pyridine,pubchem1127,g00013-watson-int,acmc-1at5w,2,3,6-trichloro-pyridine,2, 3, 5-trichloropyridine,ksc179q6d,tpc-i005 PubChem CID: 27666 IUPAC Name: 2,3,5-trichloropyridine SMILES: C1=C(C=NC(=C1Cl)Cl)Cl
3-Amino-6-bromo-2-chloropyridine 98.0+%, TCI America™
CAS: 169833-70-9 Molecular Formula: C5H4BrClN2 Molecular Weight (g/mol): 207.455 MDL Number: MFCD04971930 InChI Key: YCECOMBEVDPUJG-UHFFFAOYSA-N PubChem CID: 2050085 IUPAC Name: 6-bromo-2-chloropyridin-3-amine SMILES: C1=CC(=NC(=C1N)Cl)Br
3,5-Dichloro-4-hydroxypyridine 98.0+%, TCI America™
CAS: 17228-70-5 Molecular Formula: C5H3Cl2NO Molecular Weight (g/mol): 163.99 MDL Number: MFCD00051673,MFCD00047448 InChI Key: YKCQWIYRLMNGMO-UHFFFAOYSA-N Synonym: 3,5-dichloropyridin-4-ol,3,5-dichloro-4-hydroxypyridine,3,5-dichloro-4-pyridone,3,5-dichloro-4-pyridinol,4 1h-pyridinone, 3,5-dichloro,3,5-dichloro-4 1h-pyridinone,4-pyridinol, 3,5-dichloro,3,5-dichlorohydropyridin-4-one,pubchem2583,acmc-209e4a PubChem CID: 87011 IUPAC Name: 3,5-dichloro-1,4-dihydropyridin-4-one SMILES: ClC1=CNC=C(Cl)C1=O
2-Chloro-6-methylnicotinic Acid 98.0+%, TCI America™
CAS: 30529-70-5 Molecular Formula: C7H6ClNO2 Molecular Weight (g/mol): 171.58 MDL Number: MFCD00134165 InChI Key: ACQXHCHKMFYDPM-UHFFFAOYSA-N Synonym: 2-chloro-6-methylnicotinic acid,2-chloro-6-methyl-3-pyridinecarboxylic acid,2-chloro-6-methylnicotinicacid,6-methyl-2-chloro nicotinic acid,3-pyridinecarboxylic acid, 2-chloro-6-methyl,pubchem11019,acmc-209hgo,ksc223m1b,2-chloro-6-methyl nicotinic acid,2-chloro-6-methyl-nicotinic acid PubChem CID: 121724 IUPAC Name: 2-chloro-6-methylpyridine-3-carboxylic acid SMILES: CC1=NC(=C(C=C1)C(=O)O)Cl
2-Bromo-5-cyanopyridine 97.0+%, TCI America™
CAS: 139585-70-9 Molecular Formula: C6H3BrN2 Molecular Weight (g/mol): 183.008 MDL Number: MFCD00234141 InChI Key: XHYGUDGTUJPSNX-UHFFFAOYSA-N Synonym: 2-bromo-5-cyanopyridine,6-bromonicotinonitrile,2-bromo-5-pyridinecarbonitrile,5-cyano-2-bromopyridine,6-bromo-nicotinonitrile,6-bromo-3-pyridinecarbonitrile,3-pyridinecarbonitrile, 6-bromo,pubchem5963,2-bromo-5-cyano-pyridine,acmc-209cj9 PubChem CID: 5005718 IUPAC Name: 6-bromopyridine-3-carbonitrile SMILES: C1=CC(=NC=C1C#N)Br
Methyl 6-Methylnicotinate 98.0+%, TCI America™
CAS: 5470-70-2 Molecular Formula: C8H9NO2 Molecular Weight (g/mol): 151.165 MDL Number: MFCD00006340 InChI Key: VYPPZXZHYDSBSJ-UHFFFAOYSA-N Synonym: methyl 6-methylnicotinate,methyl-6-methylnicotinate,6-methylnicotinic acid methyl ester,etoricoxib impurity e,unii-ya0k0cm5pk,methyl 6-methyl nicotinate,6-methyl-nicotinic acid methyl ester,6-methyl nicotinic acid methyl ester,ya0k0cm5pk,3-methoxycarbonyl-6-methylpyridine PubChem CID: 231548 IUPAC Name: methyl 6-methylpyridine-3-carboxylate SMILES: CC1=NC=C(C=C1)C(=O)OC
Medchemexpress LLC Vanin-1-in-3 | 2940964-70-3 | 96.2% | C17H22F3NO5 | 10MG
Vanin-1-IN-3 (OMP-7) is a small-molecule inhibitor of vanin-1 for biochemical and preclinical research. It shows potent activity in vitro and has documented formulation protocols for in vivo studies, with reported high purity and solubility guidance for experimental use.
- Potent vanin-1 inhibition (IC50 0.038 μM).
- Suitable for in vitro biochemical assays and cellular studies.
- Formulation examples provided for in vivo dosing protocols.
- High reported purity (96.2%).
- Soluble in DMSO at 100 mg/mL; ultrasonic assistance recommended.
- Appearance: colorless to light yellow oil.
- Storage stability documented for long-term and in-solvent conditions.
Medchemexpress LLC LEM-14 5mg | 1814881-70-3 | 5 MG
LEM-14 is a small-molecule inhibitor of the histone methyltransferase NSD2 used for laboratory research (CAS 1814881-70-3). It has a reported NSD2 IC50 of 132 μM and is supplied as a powder for preclinical studies.
- Small-molecule NSD2 inhibitor with reported IC50 = 132 μM.
- Molecular formula C25H26N4O4S; molecular weight 478.56.
- Purity typically 98.0% as specified by supplier.
- Supplied as a powder; store frozen to preserve stability.
- Intended for research use only, not for human or clinical use.
Medchemexpress LLC QO-40 | 1259536-70-3 | 98.8% | 100 MG
QO-40, a pyrazolo[1,5-a]pyrimidine-7(4H)-one (PPO) derivative, is a KCNQ2/KCNQ3 K+ channels activator with an EC50 of 6.94 μM. It stimulated Ca2+-activated K+ current (IK(Ca)) with an EC50 value of 2.3 μM in pituitary GH3 lactotrophs. It is for research use only and not sold to patients.
- KCNQ2/KCNQ3 K+ channels activator
- Stimulates Ca2+-activated K+ current (IK(Ca))
- Potently augments KCNQ2/3 channels
- Pyrazolo[1,5-a]pyrimidine-7(4H)-one (PPO) derivative
- High purity (98.77%)
Medchemexpress LLC LEM-14 10mg | 1814881-70-3 | 10 MG
LEM-14 is a small-molecule research compound that selectively inhibits NSD2 and has been used in cellular and in vivo studies to evaluate effects on cancer cell apoptosis and tumor response when combined with ionizing radiation.
- Selective NSD2 inhibitor with reported IC50 ≈ 132 μM.
- High purity suitable for research use (98.0%).
- Molecular formula C25H26N4O4S, molecular weight 478.56.
- Supplied in a 10 mg vial for laboratory studies.
- Used in preclinical cancer and fibrosis research applications.
Medchemexpress LLC QO-40 | 1259536-70-3 | 98.8% | 25 MG
QO-40, a pyrazolo[1,5-a]pyrimidine-7(4H)-one (PPO) derivative, is a KCNQ2/KCNQ3 K+ channels activator with an EC50 of 6.94 μM. It also stimulates Ca2+-activated K+ current (IK(Ca)) with an EC50 value of 2.3 μM in pituitary GH3 lactotrophs. For research use only, QO-40 increases KCNQ2/3 currents and potently augments KCNQ2/3 channels expressed in Chinese hamster ovary cells, shifting the half-maximal activation voltage (V(1/2)) in the hyperpolarizing direction.
- Activates KCNQ2/KCNQ3 K+ channels.
- Stimulates Ca2+-activated K+ current (IK(Ca)).
- Increases KCNQ2/3 currents in CHO cells.
- Potently augments KCNQ2/3 channels, shifting half-maximal activation voltage (V(1/2)) in hyperpolarizing direction.
Medchemexpress LLC LEM-14 50mg | 1814881-70-3 | 50 MG
LEM-14 is a research-grade small-molecule inhibitor of NSD2 (histone methyltransferase) supplied for laboratory research use only and not intended for human use.
- Potent and selective NSD2 inhibitor.
- Reported IC50 132 μM against NSD2.
- Molecular weight 478.56 g/mol.
- Chemical formula C25H26N4O4S.
- Purity approximately 98.0%.
- Available as a 50 mg solid and as a 10 mM solution in DMSO.
Medchemexpress LLC Vanin-1-IN-3 | 2940964-70-3 | 96.2% | 377.36 | 50 MG
Vanin-1-IN-3 (OMP-7) is a vanin-1 inhibitor with an IC50 of 0.038 μM. For research use only, not for sale to patients.
- IC50: 0.038 μM (vanin-1)
- Exhibits potent activity against both serum and renal vanin-1 in vivo (hamsters) at 10 mg/kg.
Medchemexpress LLC Enzomenib | 2412555-70-3 | 99.9% | 590.73 | C33H43FN6O3 | 10 MG
Enzomenib (DSP-5336) is a selective small-molecule inhibitor of the menin-MLL interaction used in research on hematological malignancies. Provided as a high-purity solid for in vitro and preclinical studies.
- High purity (99.9%).
- Supplied as a 10 MG quantity suitable for small-scale studies.
- Chemical formula: C33H43FN6O3; molecular weight: 590.73.
- Suitable for biochemical, cellular, and preclinical assays.
- Safety and identification data available in the SDS and product literature.