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Filtered Search Results
Medchemexpress LLC H4 Receptor antagonist 1 | 848217-00-5 | 99.7% | 316.79 | 100 MG
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H4 Receptor antagonist 1 is a potent and selective histamine H4 receptor inverse agonist with an IC50 of 19 nM. It is intended for research use only. In vitro studies demonstrate its activity against the H4 receptor at 19 nM IC50. In vivo, it exhibits very low metabolic stability in rat microsomes, with only 1% of the parent compound remaining after 10 minutes.
- Potent and selective histamine H4 receptor inverse agonist.
- IC50 of 19 nM for the H4 receptor.
- Suitable for in vitro studies.
- Exhibits low metabolic stability in rat microsomes in vivo.
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Apexbio Technology LLC KN-92 hydrochloride 1431698-47-3 10mM (in 1mL DMSO)
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KN-92 hydrochloride is an inactive structural analog of the Ca /calmodulin-dependent protein kinase II (CaMKII) inhibitor KN-93 serving primarily as a comparative control compound in biological research Unlike KN-93 KN-92 hydrochloride lacks meaningful inhibitory activity against CaMKII exhibiting a much higher Ki value ( 100 M) In experimental models it is utilized to distinguish CaMKII-dependent molecular and physiological responses particularly in studies of early afterdepolarizations (EADs) and cardiac repolarization events Based on these properties KN-92 hydrochloride is applied as a negative control in cardiac electrophysiological research
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Medchemexpress LLC 2-Chloropyrimidine-5-carboxylic acid | 374068-01-6 | 100.0% | C₅H₃ClN₂O₂ | 500 G
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2-Chloropyrimidine-5-carboxylic acid is a drug intermediate used for the synthesis of various active compounds.
- Solid appearance
- White to light yellow color
- Soluble in DMSO at 100 mg/mL
- Recommended storage at 4°C under nitrogen
- Recommended storage in solvent at -80°C for 6 months or -20°C for 1 month under nitrogen
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000369951 HC-7366 250MG
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eMolecules ETHYL 2-4 4 5 5-TETRAMETH 25G
5000216424 ETHYL 2-4 4 5 5-TETRAMETH 25G
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eMolecules PYRIMIDINE-4-CARBOXALDEHYDE 5G
5000217350 PYRIMIDINE-4-CARBOXALDEHYDE 5G
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Apexbio Technology LLC Rofecoxib 162011-90-7 250mg
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Rofecoxib (CAS 162011-90-7) is a selective inhibitor of cyclooxygenase-2 (COX-2) designed to provide anti-inflammatory effects with improved gastrointestinal tolerance compared to non-selective NSAIDs It demonstrates potent inhibition of COX-2 in cell-based assays with IC50 values ranging from 18 to 46 nM In osteosarcoma cells Rofecoxib suppresses prostaglandin E2 (PGE2) synthesis (IC50 26 nM) and inhibits recombinant human COX-2 in stably transfected CHO cells (IC50 18 nM) In biochemical assays using purified human COX-2 the IC50 is 0 34 M In vivo Rofecoxib reduces carrageenan-induced edema and hyperalgesia in rats (ID50 1 1 5 mg/kg) It is widely used in studies investigating COX-2-mediated inflammatory pathways and analgesia
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000431268 POSACONAZOLE IMPURIT 250MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000431271 NORDIHYDROGUAIARETIC 250MG
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Medchemexpress LLC 5-Methyl-1-Tritylim 10g | 10G
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5-Methyl-1-Tritylim 10g | 10G
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Selleck Chemical LLC Ethyl caffeate
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Ethyl caffeate a naturally occurring compound found in Bidens pilosa suppresses NF-kappaB activation and its downstream inflammatory mediators iNOS COX-2 and PGE2 in vitro
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000430423 COLLAGENASE TYPE I 250MG
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Medchemexpress LLC 5,6-Dihydro-5-methyluracil (Dihydrothymine) | 696-04-8 | MFCD00023159 | 100 MG
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5,6-Dihydro-5-methyluracil (Dihydrothymine) is an intermediate breakdown product of thymine, which is found in animals or plants. It is identified as a Human Endogenous Metabolite and an Endogenous metabolite of Human Gut Microbiota.
- Intermediate breakdown product of thymine
- Found in animals or plants
- Human endogenous metabolite
- Endogenous metabolite of human gut microbiota
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eMolecules Ambeed / 5-((34-Dimethoxyphenethyl)(methyl)amino)-2-(34-dimethoxyphenyl)-2-isopropylpentanenitrile / 100mg / 534084106 / A149080 / / 52-53-9 / MFCD00056240 / 454.611 / C27H38N2O4
Ambeed / 5-((34-Dimethoxyphenethyl)(methyl)amino)-2-(34-dimethoxyphenyl)-2-isopropylpentanenitrile / 100mg / 534084106 / A149080 / / 52-53-9 / MFCD00056240 / 454.611 / C27H38N2O4
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eMolecules R--2-METHYL-2-PROPAN 250G
5000216615 R--2-METHYL-2-PROPAN 250G
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