Pyrroles
Medchemexpress LLC HY-14397 1g Medchemexpress, Indomethacin CAS:53-86-1 Purity:>98%
Medchemexpress, HY-14397 1g Indomethacin CAS:53-86-1 Indomethacin (Indometacin) is a potent, blood-brain permeable and nonselective inhibitor of COX1 and COX2, with IC50s of 18 nM and 26 nM for human COX-1 and COX-2, respectively, in CHO cells. Indomethacin disrupts autophagic flux by disturbing the normal functioning of lysosomes[2]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC 2-Acetylpyrrole | 1072-83-9 | 99.5% | 109.13 | 10 G
2-Acetylpyrrole is an organic compound featuring a pyrrole ring. It is a natural product of the Maillard browning reaction and is recognized as a significant flavor component in various foods. This compound also functions as an intermediate in the synthesis of other active compounds, such as the flavor compound 2-acetyl-1-pyrroline. For in vitro applications, 2-Acetylpyrrole reacts with nitrite to produce 1-nitro-2-acetylpyrrole (NAP) and 1,3,5-trinitro-2-acetylpyrrole (TNAP), which have demonstrated moderate mutagenicity and strong cytotoxicity.
- Organic compound with a pyrrole ring
- Product of Maillard browning reaction
- Major flavor component in many foods
- Intermediate in synthesis of other active compounds
- Suitable for research and analytical applications
- Reacts with nitrite to form nitropyrrole compounds
Medchemexpress LLC HY-79077 5mg Medchemexpress, Osimertinib (dimesylate) CAS:2070014-82-1 Purity:>98%
Medchemexpress, HY-79077 5mg Osimertinib (dimesylate) CAS:2070014-82-1 Osimertinib dimesylate (AZD-9291 dimesylate) is an irreversible and mutant selective EGFR inhibitor with IC50s of 12 and 1 nM against EGFRL858R and EGFRL858R/T790M, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC JNJ-63576253 | 100MG
JNJ-63576253 (TRC-253) is a potent and orally active full antagonist of androgen receptor (AR) with IC50s of 37 and 54 nM for F877L mutant AR and wild-type AR in LNCaP cells JNJ-63576253 can be used for the research of castration-resistant prostate cancer (CRPC)[1]
Medchemexpress LLC HY-101971 5mg Medchemexpress, AZ PFKFB3 26 CAS:1704740-52-2 Purity:>98%
Medchemexpress, HY-101971 5mg AZ PFKFB3 26 CAS:1704740-52-2 AZ PFKFB3 26 is a potent and selective inhibitor of the metabolic kinase PFKFB3 with an IC50 of 23 nM. AZ PFKFB3 26 inhibits PFKFB1 and PFKFB2 with IC50s of 2.06 and 0.384 μM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC (Z)-leukadherin-1 choline | 2055362-74-6 | 98.0% | 524.65 g/mol | C27H28N2O5S2 | 10 MG
ADH-503 ((Z)-Leukadherin-1 choline) is an orally active, allosteric CD11b agonist used in preclinical research to modulate tumor-associated macrophage polarization and immune responses. The compound has formula C27H28N2O5S2, molecular weight 524.65 g/mol, CAS 2055362-74-6, and is supplied at research-grade purity (~98%).
- Orally active allosteric CD11b agonist for immunology research.
- Promotes repolarization of tumor-associated macrophages.
- High purity suitable for preclinical studies.
- Soluble in common organic solvents such as methanol, DMSO, and ethanol.
- Available in common research pack sizes including 10 mg.
eMolecules 475489-16-8 | Medchem Express | NVP-AEW541 | 5mg | 446271158 | HY-50866 | MFCD22741515 | 439.563 | C27H29N5O
ChemScene | 1-(Furan-2-yl)ethan-1-amine hydrochloride | 100mg | 714104699 | CS-0247307 | 99839-15-3 | MFCD10686894 | 147.600 | C6H10ClNO
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Medchemexpress LLC HY-106150B 5mg Medchemexpress, Eniporide hydrochloride CAS:211813-86-4 Purity:>98%
Medchemexpress, HY-106150B 5mg Eniporide HCl CAS:211813-86-4 Eniporide hydrochloride (EMD-96785 hydrochloride) is a potent Na+/H+ exchange inhibitor. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC 3-(cyclopropylmethyl)-7-((4-phenylpiperidin-1-yl)methyl)-8-(trifluoromethyl)-triazolopyridine | 1254980-38-5 | 98.8% | 5 MG
JNJ-46281222 is an mGlu2-selective positive allosteric modulator used as a research tool in receptor binding and functional assays; it has nanomolar affinity and is supplied as a high-purity solid or DMSO solution for in vitro studies.
- Metabotropic glutamate receptor 2 (mGlu2)-selective positive allosteric modulator
- High affinity: Kd = 1.7 nM
- Functional potency: pEC50 = 7.71 (EC50 ≈ 19-21 nM in CHO assays)
- Molecular formula C23H25F3N4; molecular weight 414.47 g·mol-1
- High purity (98.77%)
- Available as solid powder and as 10 mM solution in DMSO
- Storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months)
- For research use only; not for human or clinical use
eMolecules 393105-53-8 | Medchem Express | Tiplaxtinin | 5mg | 446265275 | HY-15253 | MFCD09475615 | 439.39 | C24H16F3NO4
ChemScene | 2-(2-Chloro-4-fluorophenyl)-4455-tetramethyl-132-dioxaborolane | 100mg | 714185624 | CS-0279218 | 892845-64-6 | MFCD18729910 | 256.510 | C12H15BClFO2
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eMolecules 1620278-72-9 | Medchem Express | TLR7/8 agonist 1 (dihydrochloride) | 5mg | 446258353 | HY-103698A | 432.39 | C22H27Cl2N5
ChemScene | 7-Fluoroquinolin-3-amine | 100mg | 714105228 | CS-0449796 | 225366-89-2 | MFCD15526746 | 162.167 | C9H7FN2
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Medchemexpress LLC Kw-8232 methanesulfonate | 217813-15-5 | 98.1% | 705.26 g·mol⁻¹ | C37H41ClN4O6S | 100 MG
KW-8232 methanesulfonate is an orally active anti-osteoporotic small molecule that reduces prostaglandin E2 (PGE2) biosynthesis in osteoblastic cells and has been shown to inhibit bone loss in preclinical studies. It is supplied for research use in solid form and as a 10 mM solution in DMSO.
- Orally active anti-osteoporotic agent.
- Reduces prostaglandin E2 (PGE2) biosynthesis in osteoblastic cells.
- Demonstrated inhibition of bone loss in preclinical models.
- High purity (98.1%).
- Molecular weight 705.26 g·mol⁻¹; formula C37H41ClN4O6S.
- Available as solid and as a 10 mM solution in DMSO for in vitro and in vivo studies.
Selleck Chemical LLC Ondansetron Hydrochloride Dihydrate S4748-50mg
Ondansetron is a highly specific and selective serotonin 5-HT3 receptor antagonist (Ki 6 16 nM) with low affinity for dopamine receptors
Medchemexpress LLC TLR7 agonist 3 | 1229024-78-5 | MFCD34179471 | 99.9% | 312.41 g/mol | C18H24N4O | 50 MG
TLR7 agonist 3 is a synthetic small-molecule agonist of toll-like receptor 7 supplied as a high-purity white to off-white powder for preclinical and research use. It is suitable for biochemical and cellular assays probing innate immune signaling and is available as a solid and as a 10 mM solution in DMSO. Follow recommended storage and handling instructions for stability. For research use only.
- High purity suitable for assay work (reported 99.9%).
- Molecular weight 312.41 g/mol; formula C18H24N4O.
- Available as powder and 10 mM solution in DMSO.
- Store powder at 4 °C (short term) or -20 °C (long term); store solutions at -20 °C or -80 °C.
- Intended for laboratory research use only.