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Filtered Search Results
Medchemexpress LLC Terlipressin diacetate | 1884420-36-3 | 99.8% | 1347.48 | C56H82N16O19S2 | 100MG
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Terlipressin diacetate is a vasopressin analogue and a selective vasopressin V1 receptor agonist used in research to reduce splanchnic blood flow and portal pressure. It is applied in studies of acute variceal bleeding, hepatorenal syndrome, and norepinephrine-resistant septic shock, and shows anti-inflammatory and anti-oxidative effects. Supplied as a purified peptide with recommended frozen storage to preserve stability.
- High purity suitable for research applications.
- Selective vasopressin V1 receptor agonist activity.
- Relevant for models of portal hypertension and variceal bleeding.
- Exhibits anti-inflammatory and anti-oxidative properties.
- Storage recommendations minimize degradation and extend shelf life.
- Available in multiple pack sizes for flexible experimental needs.
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Enzo Life Sciences ET A receptor antagonist [BQ-610] (1mg). CAS: 141595-53-1
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30-fold more potent ETA antagonist than BQ-123 in pig aortic smooth muscle membrane assay, same activity as BQ-123 when tested on pig cerebellum membrane. Formula: C36H44N6O6. MW: 656.8. Long Term Storage: -20°C.
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Medchemexpress LLC PROTAC CDK2/9 Degrader-1 | 2408641-24-5 | 99.9% | 50 MG
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PROTAC CDK2/9 Degrader-1 (Compound F3) is a potent dual degrader for CDK2 (DC50=62 nM) and CDK9 (DC50=33 nM). It suppresses prostate cancer PC-3 cell proliferation (IC50=0.12 μM) by effectively blocking the cell cycle in S and G2/M phases. This compound is a PROTAC that functions by tethering a CDK inhibitor with a Cereblon ligand.
- Potent dual degrader for CDK2 and CDK9
- Suppresses prostate cancer PC-3 cell proliferation
- Functions by tethering a CDK inhibitor with a Cereblon ligand
- Induces cell cycle blockage at the G2/M phase
- Down-regulates Mcl-1 protein level
- Effectively degrades CDK2/9 in various cell lines
- Inhibits both CDK2 and CDK9
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Medchemexpress LLC PROTAC K-Ras Degrader-1 | 2378258-52-5 | 99.9% | 10 MG
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PROTAC K-Ras Degrader-1 (Compound 518) is a PROTAC (Proteolysis Targeting Chimeras) that effectively degrades K-Ras. It is designed to work based on a Cereblon E3 ligand and exhibits a degradation efficacy of ≥70% in SW1573 cells. PROTACs function by leveraging the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Effectively degrades K-Ras
- Functions based on a Cereblon E3 ligand
- Exhibits ≥70% degradation efficacy in SW1573 cells
- Utilizes the intracellular ubiquitin-proteasome system for selective protein degradation
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Apexbio Technology LLC Alarelin Acetate,50mg CAS# 79561-22-1
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Alarelin (Gonadotrophin-releasing hormone) is a synthetic GnRH agonist. Alarelin is found in higher amounts than that of LH-RH in rat hypophyseal stimulation of gonadotropin secretion in vivo and in vitro and in ovulation inductions. Alarelin is known for its induction of ovulation and is used to treat endmometriosis. Alarelin Acetate is the acetate form of a hypothalamic peptide that stimulates the release of FSH and LH from the pituitary gland. Other sizes are also available. Please inqury us for quote.
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Innovative Research Inc Hmn PAI1 Rcmb WT Act 50ug
Human PAI-1 Recombinant Wild Type Active 50ug - Human PAI-1 Recombinant Wild Type Active from Innovative Research has been recombinantly produced in E. coli and purified by affinity chromatography. This is a Frozen liquid buffered in 0.05M Sodium Phosphate; 0.1M NaCl; 1mM EDTA; pH 6.6 and a purity of >95% as determined by SDS-PAGE. More Details Species Human Target PAI-1 Purification Method Affinity purified Purity >95% as determined by SDS-PAGE Analysis Source E. coli Storage Conditions -70C Additional Information Gentle purification conditions create an active fraction that is greater than 99% pure and 98% active. This product can be used as a control in applications like ELISA and Western Blot. It can be used in a wide range of in vitro applications, including blocking/inhibition, fibrinolysis, plasminogen activation, receptor binding, in hypertension studies, for protein-protein interactions, and more.
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Medchemexpress LLC Protac BRD4 degrader-5-co-peg3-n3 | 2704602-92-4 | 99.7% | 1231.87 | C58H75ClN12O12S2 | 10 MG
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PROTAC BRD4 Degrader-5-CO-PEG3-N3 is a PROTAC-linker conjugate that combines a BRD4 degrader with a PEG-based linker and an azide functional group for bioconjugation. It is provided as a high-purity research reagent for targeted protein degradation studies and click-chemistry applications.
- azide functional group enables CuAAC and SPAAC conjugation
- high purity suitable for research use
- molecular weight 1231.87 and formula C58H75ClN12O12S2
- available in small milligram quantities, including 10 mg
- designed for use in antibody conjugation and linker chemistry workflows
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Medchemexpress LLC Protac EED degrader-1 | 2639882-72-5 | 98.3% | C55H60FN11O8S | 10MG
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PROTAC EED degrader-1 is a von Hippel-Lindau (VHL)-based proteolysis targeting chimera designed to bind and induce degradation of EED, a subunit of the polycomb repressive complex 2 (PRC2). It exhibits potent biochemical and cellular activity, leads to downregulation of EZH2 and H3K27me3, and has shown cellular apoptosis and antitumor effects in preclinical models.
- Potent EED-targeting degrader with low nanomolar biochemical activity.
- Reduces EZH2 protein levels and decreases H3K27me3 in cells.
- Induces apoptosis and shows antitumor activity in preclinical models.
- High reported purity for research applications.
- Available in multiple small-scale quantities for laboratory studies.
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eMolecules 2639528-48-4 | Medchem Express | (SRS)-AHPC-Me-C7 ester | 50mg | 686240373 | HY-130640 | 614.8 | C32H46N4O6S
Ambeed | 4-Ethynylbenzaldehyde | 1g | 552665775 | A234214 | 63697-96-1 | MFCD05664348 | 130.146 | C9H6O
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Medchemexpress LLC HY-10900 10mg Medchemexpress, TCS 1102 CAS:916141-36-1 Purity:>98%
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Medchemexpress, HY-10900 10mg TCS 1102 CAS:916141-36-1 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Apexbio Technology LLC Rac GTPase fragment 5mg
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Rac GTPase fragment is a synthetic peptide representing a segment of the small signaling protein Rac a member of the Rho family of GTPases It is designed to serve as a molecular tool to investigate Rac-mediated modulation of actin dynamics and kinase activation processes essential for cytoskeletal rearrangement cell-cycle progression differentiation and cell adhesion Rac GTPase fragment exerts its biological activity by serving as a probe for Rac-driven signaling pathways Based on these pharmacological properties Rac GTPase fragment holds research potential in studying tumor biology particularly the development and progression of melanoma and non-small-cell lung carcinoma
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Ambeed AMBEED
5000882388 1-CBZ-PYRROLIDINE 5G
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Medchemexpress LLC HY-111593 5mg Medchemexpress, Homo-PROTAC pVHL30 degrader 1 CAS:2244684-49-7 Purity:>98%
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Medchemexpress, HY-111593 5mg Homo-PROTAC pVHL30 degrader 1 CAS:2244684-49-7 Homo-PROTAC pVHL30 degrader 1 is a potent pVHL30 degrader based on PROTAC [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Teneligliptin (hydrobromide hydrate) | 1572583-29-9 | >99.9% | 426.58 | 100 MG
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Teneligliptin (hydrobromide hydrate) | 1572583-29-9 | >99.9% | 426.58 | 100 MG
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Medchemexpress LLC HY-15298A 10mg Medchemexpress, Grazoprevir potassium salt CAS:1206524-86-8 Purity:>98%
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Medchemexpress, HY-15298A 10mg Grazoprevir potassium salt CAS:1206524-86-8 Grazoprevir potassium salt (MK-5172 potassium salt) is a selective inhibitor of Hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants, with Kis of 0.01 nM (gt1b), 0.01 nM (gt1a), 0.08 nM (gt2a), 0.15 nM (gt2b), 0.90 nM (gt3a), respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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