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Filtered Search Results
Medchemexpress LLC Rac-PF-06256142 | 1609580-97-3 | 99.6% | 1 ML
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The racemic form of PF-06256142 is a D1 dopamine receptor agonist supplied as a 10 mM solution in DMSO for research use. It is intended for in vitro and in vivo pharmacology studies of D1 receptor signaling.
- Racemic D1 receptor agonist with EC50 107 nM.
- Supplied as a 10 mM solution in DMSO, 1 mL vial.
- High purity suitable for research applications.
- Molecular weight 356.38 g/mol; formula C21H16N4O2.
- Soluble in DMSO (25 mg/mL) and compatible with multiple in vivo vehicles.
- Stable under recommended storage conditions for powder and solution.
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Medchemexpress LLC (Rac)-dehydrocostus lactone | 74299-48-2 | MFCD00210277 | 99.9% | 230.30 g·mol⁻1 | C15H18O2 | 100 MG
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(Rac)-Dehydrocostus lactone is a naturally occurring sesquiterpene lactone offered for research use. It exhibits reported anti-inflammatory, anticancer, antiviral, and antimicrobial activities and is intended as a high-purity analytical standard for in vitro and biochemical studies.
- High purity: 99.9%.
- Molecular formula: C15H18O2; molecular weight: 230.30 g·mol⁻1.
- CAS number: 74299-48-2.
- Supplied quantity: 100 MG.
- Suitable as a reference standard for biological assays and analytical method development.
- Includes datasheet with spectral and purity data.
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Medchemexpress LLC (Rac)-Etavopivat | 2622070-93-1 | 99.9% | 457.50 | 50 MG
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(Rac)-Etavopivat, also known as (Rac)-FT-4202, is an isomer of Etavopivat. This orally active erythrocyte pyruvate kinase-R (PKR) activator is utilized in studies related to sickle cell disease and other hemoglobinopathies.
- Improves hemoglobin-oxygen affinity and reduces the sickle point in human red blood cells.
- Increases 2,3-DPG and ATP in crab-eating monkeys.
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eMolecules 163457-23-6 | 3,3-DIFLUORO-PYRROLIDINE HCL | AstaTech | MFCD03788948 | 143.560 | C4H8ClF2N | 97.000 | Cl.FC1(F)CCNC1 | 1g | 200611687
3,3-DIFLUORO-PYRROLIDINE HCL | AstaTech | 163457-23-6 | MFCD03788948 | 143.560 | C4H8ClF2N | 97.000 | Cl.FC1(F)CCNC1 | 1g | 200611687
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Medchemexpress LLC Azido-PEG8-azide | 361543-07-9 | 98.2% | 464.51 | 250 MG
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Azido-PEG8-azide is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a versatile click chemistry reagent, featuring an Azide group that enables its participation in various cycloaddition reactions. This compound is suitable for both copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules and strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker
- Utilized in PROTAC synthesis
- Functions as a click chemistry reagent
- Contains an Azide group for reaction versatility
- Compatible with copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Enables strain-promoted alkyne-azide cycloaddition (SPAAC)
- For research use only
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Medchemexpress LLC Rac -Shin2 5Mg | HY-134978-5MG
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Rac -Shin2 5Mg
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Medchemexpress LLC Azido-PEG7-azide | 225523-86-4 | 95.0% | C16H32N6O7 | 10MG
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Azido-PEG7-azide is a bifunctional polyethylene glycol (PEG7) linker terminating in azide groups. It is used as a click-chemistry reagent and as a PROTAC linker to join molecules via azide-alkyne cycloaddition, providing a hydrophilic spacer that improves solubility and molecular flexibility for bioconjugation and linker synthesis.
- Terminal azide groups suitable for CuAAC and SPAAC reactions.
- Seven-unit PEG spacer increases solubility and reduces steric hindrance.
- Useful for bioconjugation and PROTAC linker construction.
- Offered in multiple small package sizes for research use.
- Store dry and cool; in solution store at -80°C (long term) or -20°C (short term).
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Medchemexpress LLC Rac-SCH 563705 | 473728-58-4 | 99.8% | 425.48 | C23H27N3O5 | 50 MG
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(Rac)-SCH 563705 is the racemic form of a potent, orally active antagonist of chemokine receptors CXCR2 and CXCR1, supplied as a high-purity research compound for in vitro and in vivo studies. It exhibits low-nanomolar receptor potency and is provided with analytical documentation and handling guidance.
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Medchemexpress LLC (Rac)-AMG8379 ((Rac)-AMG8380) | 1641574-26-6 | 99.25% | 543.93 | 10 MG
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(Rac)-AMG8379, also known as (Rac)-AMG8380, is a racemate of AMG8379. It is described as a potent, orally active, and selective sulfonamide antagonist of NaV1.7. It exhibits IC50 values of 8.5 nM for hNaV1.7 and 18.6 nM for mNaV1.7.
- Potent NaV1.7 antagonist.
- Orally active compound.
- Selective sulfonamide.
- Available in various quantities for research needs.
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eMolecules 1280214-48-3 | 5-tert-butoxycarbonyl-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-3-carboxylic acid | Synthonix | MFCD22571359 | 267.285 | C12H17N3O4 | 97.000 | CC(C)(C)OC(=O)N1CCn2ncc(C(O)=O)c2C1 | 100mg | 808542809
5-tert-butoxycarbonyl-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-3-carboxylic acid | Synthonix | 1280214-48-3 | MFCD22571359 | 267.285 | C12H17N3O4 | 97.000 | CC(C)(C)OC(=O)N1CCn2ncc(C(O)=O)c2C1 | 100mg | 808542809
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eMolecules 83435-58-9 | (R)-(+)-1-Boc-2-pyrrolidinemethanol | Ambeed | MFCD00040580 | 201.266 | C10H19NO3 | 97.000 | CC(C)(C)OC(=O)N1CCC[C@@H]1CO | 1g | 490551443
(R)-(+)-1-Boc-2-pyrrolidinemethanol | Ambeed | 83435-58-9 | MFCD00040580 | 201.266 | C10H19NO3 | 97.000 | CC(C)(C)OC(=O)N1CCC[C@@H]1CO | 1g | 490551443
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Medchemexpress LLC (Rac)-Razpipadon | 1643462-93-4 | 97.1% | C19H17F2N3O4 | 100 MG
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(Rac)-Razpipadon, also known as PW0464, is a nanomolar potent, complete G protein biased ligand. It functions as a noncatechol D1R agonist, demonstrating an EC50 of 5.8 nM (Gs-cAMP). This compound exhibits complete G protein bias, with no activity observed for D1R-mediated β-arrestin recruitment.
- Exhibits agonist activity at D5R with an EC50 of 12 nM in HEK293 cells.
- Demonstrates agonist activity at wild type human D1R with an EC50 of 5.3 nM in HEK293 cells.
- Forms bonds with S1985.42 and S2025.46 via its fluorine atom.
- Elicits complete G protein bias, showing no activity for D1R-mediated β-arrestin recruitment.
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Medchemexpress LLC C12-TLRa | 3067466-15-0 | 99.0% | 728.10 g/mol | C46H73N5O2 | 10 MG
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C12-TLRa is an ionized adjuvant lipid that acts as a toll-like receptor 7/8 (TLR7/8) agonist in endosomes. It is used as a structural component in lipid nanoparticles to enhance mRNA delivery and to stimulate innate immune responses; common research uses include mRNA vaccine formulation and immunostimulatory studies.
- Ionized adjuvant lipid targeting TLR7/8 receptors.
- Enhances mRNA delivery when formulated in lipid nanoparticles.
- Promotes innate immune responses for vaccine research.
- High purity: 99.0%.
- Molecular weight 728.10 g/mol; formula C46H73N5O2.
- Provided as a solid suitable for formulation and analytical use.
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eMolecules 1009075-44-8 | tert-Butyl n-[(1r,3r)-3-aminocyclopentyl]carbamate | Advanced ChemBlocks - In Stock200.282 | C10H20N2O2 | 97.000 | CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](N)C1 | 250mg | 381420255
tert-Butyl n-[(1r,3r)-3-aminocyclopentyl]carbamate | Advanced ChemBlocks - In Stock | 1009075-44-8200.282 | C10H20N2O2 | 97.000 | CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](N)C1 | 250mg | 381420255
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Medchemexpress LLC (2R,3R)-Firazorexton | 2692692-00-3 | 99.9% | 470.51 g/mol | C22H25F3N2O4S | 5 MG
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(2R,3R)-Firazorexton is an orally active, brain-penetrating orexin type 2 receptor (OX2R) agonist supplied for research use. It is offered as a solid powder and as a DMSO solution for in vitro and preclinical pharmacology studies addressing orexin signaling and narcolepsy-like models.
- Orally active OX2R agonist for pharmacology research.
- Provided as solid powder and 10 mM DMSO solution.
- High purity (~99.85%) suitable for research assays.
- Soluble in DMSO (≈200 mg/mL); ultrasonic assistance may be required.
- Store powder at -20°C; store in solvent at -80°C for extended stability.
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