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Filtered Search Results
Aobchem AOBCHEM
5000994019 N- 3-BROMOPHENYL MALEIMIDE 5G
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eMolecules 262438-43-7 | ATN-161 | MFCD30478885 | 50mg
Ambeed | 2-Chloro-3-hydrazinylpyrazine | 250mg | 552743627 | A562796 | 63286-28-2 | MFCD08272804 | 144.560 | C4H5ClN4
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eMolecules 77-86-1 | 2-Amino-2-(hydroxymethyl)-1,3-propanediol | Chem-Impex | MFCD00004679 | 121.136 | C4H11NO3 | 99.000 | NC(CO)(CO)CO | 10kg | 272384826
2-Amino-2-(hydroxymethyl)-1,3-propanediol | Chem-Impex | 77-86-1 | MFCD00004679 | 121.136 | C4H11NO3 | 99.000 | NC(CO)(CO)CO | 10kg | 272384826
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Medchemexpress LLC 3-Maleimidopropionic acid | 7423-55-4 | 99.83% | 169.13 | 500 MG
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3-Maleimidopropionic acid is an alkyl chain-based PROTAC linker used in the synthesis of PROTACs. These compounds facilitate the selective degradation of target proteins by exploiting the intracellular ubiquitin-proteasome system. For research use only.
- Alkyl chain-based PROTAC linker
- Facilitates synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
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5000281617 2 5-DIOXO-1-PYRROLI 50MG
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5000695833 R S R S R-BOC-DAP- 100MG
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5000695877 R S S S R-BOC-DAP- 5MG
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5000695878 AZIDO-PEG4-CH2-BOC 10G
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5000695885 R S R S R-BOC-DAP- 10MG
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Medchemexpress LLC Protac PD-1/PD-L1 degrader-1 | 2447066-37-5 | 99.5% | C59H58ClN7O11 | 10MG
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PROTAC PD-1/PD-L1 degrader-1 is a cereblon-based proteolysis targeting chimera designed to disrupt PD-1/PD-L1 interaction and induce degradation of PD-L1 in cells. It demonstrates potent cellular activity and has been applied in co-culture models to restore immune responses via a lysosome-dependent mechanism.
- High purity suitable for cellular and biochemical assays.
- Potent cellular activity (IC50 39.2 nM).
- Cereblon E3 ligase-mediated degradation mechanism.
- Reduces PD-L1 protein levels in a lysosome-dependent manner.
- Suitable for studies of immune checkpoint modulation and PD-L1 biology.
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Aobchem AOBCHEM
5000982546 2 3-DIFLUORO-4- HYDROXYMETHYL
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Sigma Aldrich Fine Chemicals Biosciences N Ethylmaleimide crystalli100G
N Ethylmaleimide crystalli100G
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5000770718 8-BOC-8-AZASPIRO4.5 250MG
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eMolecules 142356-33-0 | N-Boc-6-Bromohexylamine | Chem-Impex | MFCD06201019 | 280.206 | C11H22BrNO2 | 95.000 | CC(C)(C)OC(=O)NCCCCCCBr | 1g | 272389991
N-Boc-6-Bromohexylamine | Chem-Impex | 142356-33-0 | MFCD06201019 | 280.206 | C11H22BrNO2 | 95.000 | CC(C)(C)OC(=O)NCCCCCCBr | 1g | 272389991
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5000760561 BOC-C4-ETHYNE 5G
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