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Filtered Search Results
Medchemexpress LLC Maleimide | 541-59-3 | 97.07 | 5 G
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Maleimide can be used for the production of antibody-drug conjugate (ADC) in cancer research. It can also be leveraged for the preparation of fluorogenic probes, which are mainly used for the specific detection of thiol analytes.
- Used in the production of antibody-drug conjugates (ADCs) for cancer research.
- Can be used for the preparation of fluorogenic probes for specific detection of thiol analytes.
- Binds rapidly and covalently to the sulfhydryl (-SH) group of cysteine residues.
- Can be used in drug delivery systems for improved cell uptake efficiency.
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Medchemexpress LLC Amino-PEG4-Val-Cit-PAB-MMAE | 1492056-71-9 | 99.9% | 1370.71 g/mol | C69H115N11O17 | 5 MG
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Amino-PEG4-Val-Cit-PAB-MMAE is a cleavable four-unit PEG linker terminating in an amino group and bearing a Val-Cit-PAB cleavable spacer attached to monomethyl auristatin E (MMAE). It is supplied for research use and is used in the synthesis of antibody-drug conjugates (ADCs).
- Cleavable Val-Cit-PAB spacer linking to MMAE.
- Four-unit PEG spacer with amino terminal.
- High purity: 99.93% (manufacturer reported).
- Molecular weight approximately 1370.71 g/mol.
- Chemical formula: C69H115N11O17.
- Soluble in DMSO; in-vivo formulation guidance provided by manufacturer.
- Store sealed at -20°C; unstable in solution-prepare fresh solutions.
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Medchemexpress LLC 6-maleimidohexanoic acid N-hydroxysuccinimide ester | 55750-63-5 | MFCD00043043 | 100.0% | 308.29 g/mol | C14H16N2O6 | 500 MG
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6-Maleimidohexanoic acid N-hydroxysuccinimide ester is a heterobifunctional cross-linking reagent containing maleimide and NHS ester reactive groups that enable selective conjugation between thiol and amine functionalities for preparation of hapten and enzyme immunoconjugates.
- Heterobifunctional reagent: maleimide and NHS ester groups.
- Reacts with thiols and primary amines for targeted conjugation.
- Molecular weight 308.29 g/mol; formula C14H16N2O6.
- High purity suitable for analytical and preparative applications.
- Available in multiple pack sizes, including 500 MG.
- Store sealed, away from moisture and light; store solid at -20°C.
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eMolecules Medchem Express / SB 216763 / 5mg / 446260509 / HY-12012 / / 280744-09-4 / MFCD09753369 / 371.220 / C19H12Cl2N2O2
Medchem Express / SB 216763 / 5mg / 446260509 / HY-12012 / / 280744-09-4 / MFCD09753369 / 371.220 / C19H12Cl2N2O2
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Medchemexpress LLC Go 6983 10 Mm 1 Ml In Dmso | HY-13689
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Go 6983 10 Mm 1 Ml In Dmso
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Abcam Ro 31-8220 mesylate (Bisindolylmaleimide I x ), Protein kinase inhibitor, 1MG
MW 553.7 Da, Purity >98%. Widely used as a cell-permeable, reversible, competitive protein kinase C inhibitor. Also potently inhibits wide range of kinases inlcuding RSK1, RSK2, PRK2, PKCα, PKD1, MSK1, GSK3β, CDK2-cyclin A and PIM3, as well as PKCα. Also available in simple stock solutions (ab146723) - add 1 ml of water to get an exact, ready-to-use concentration.
The product is subject to the following: Abcam Restricted Use Statement
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Medchemexpress LLC 6-maleimidohexanoic acid N-hydroxysuccinimide ester | 55750-63-5 | 100.0% | 308.29 g/mol | C14H16N2O6 | 25 G
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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6-Maleimidohexanoic acid N-hydroxysuccinimide ester is a heterobifunctional cross-linking reagent used to conjugate sulfhydryl groups to amines or carboxyl-functionalized molecules. It is non-cleavable and supplied as a high-purity solid with recommended sealed storage at low temperature.
- Heterobifunctional cross-linker for sulfhydryl-to-amine conjugation.
- High purity suitable for sensitive bioconjugation applications.
- Molecular weight 308.29 g/mol and formula C14H16N2O6.
- CAS number 55750-63-5 for unambiguous identification.
- Recommended storage: -20°C, sealed, away from moisture and light; in solvent: -80°C for long-term.
- Available in multiple pack sizes including 25 G for scale-up.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Bisindolylmaleimide VIII acetate (Ro 31-7549 acetate) | 138516-31-1 | 99.7% | 10 MG
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Bisindolylmaleimide VIII acetate (Ro 31-7549 acetate) is a potent and selective protein kinase C (PKC) inhibitor. It demonstrates inhibitory effects on various PKC isoforms including PKC-α, PKC-βI, PKC-βII, PKC-γ, and PKC-ε. This compound is known to facilitate Fas-mediated apoptosis and has shown promise in inhibiting T cell-mediated autoimmune diseases.
- Potent and selective protein kinase C (PKC) inhibitor
- Inhibits PKC-α, PKC-βI, PKC-βII, PKC-γ, and PKC-ε isoforms
- Facilitates Fas-mediated apoptosis
- Inhibits T cell-mediated autoimmune diseases
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Enterprise Technology Solutions Plantronics Savi 8220 Office Wireless DECT Headset System
Plantronics Savi 8220 Office Wireless DECT Headset System
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Medchemexpress LLC N-Ethylmaleimide | 128-53-0 | 99.89% | 5 MG
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N-Ethylmaleimide (NEM) is a compound derived from maleic acid that can alkylate free sulfhydryl groups. It acts as an irreversible cysteine protease inhibitor and specifically inhibits phosphate transport in mitochondria. It can be used to modify cysteine residues in proteins and peptides.
- Acts as an irreversible cysteine protease inhibitor
- Inhibits phosphate transport in mitochondria
- Modifies cysteine residues in proteins and peptides
- Inhibits prolyl endopeptidase with an IC50 value of 6.3 μM
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Medchemexpress LLC N-Arachidonyl maleimide | 876305-42-9 | 98.3% | 369.54 | 50 MG
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N-Arachidonyl maleimide is a potent, irreversible inhibitor of monoacylglycerol lipase (MAGL) with an IC50 value of 140 nM.
- Modulates effects of 2-arachidonyl glycerol (2-AG) by increasing endogenous levels of 2-AG in the brain
- Prevents cerebellar membrane-mediated degradation of 2-AG
- Produces dose-dependent hypothermia when combined with 2-AG
- Inhibits locomotor activity when combined with 2-AG
- Causes antinociception when combined with 2-AG
- Induces catalepsy when combined with 2-AG
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Chem-Impex International, Inc. N-Ethylmaleimide | 128-53-0 | MFCD00005509 | 25G
N-Ethylmaleimide, 128-53-0, MFCD00005509, 25G
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Sigma Aldrich Fine Chemicals Biosciences 6-Maleimidohexanoic acid N25MG
6MALEIMIDOHEXANOIC 6-Maleimidohexanoic acid N25MG
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Medchemexpress LLC Fluorescein-5-maleimide (N-(5-Fluoresceinyl)maleimide) | 75350-46-8 | 99.5% | 50 MG
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Fluorescein-5-maleimide (N-(5-Fluoresceinyl)maleimide) | 75350-46-8 | 99.5% | 50 MG
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Sigma Aldrich Fine Chemicals Biosciences Maleimide PEG5K OH average1G
Maleimide PEG Hydroxyl. Maleimide is thiol reactive and Hydroxyl is stable.
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