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Filtered Search Results
Medchemexpress LLC DL-Dipalmitoylphosphatidylcholine-d80 (DL-DPPC-d80) | 100412-79-1 | 99.0% | 814.53 | 1 MG
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DL-Dipalmitoylphosphatidylcholine-d80 (DL-DPPC-d80) is a deuterium labeled 16:0 (Rac)-PC. This compound serves as a tracer and an internal standard in various analytical techniques. Stable heavy isotopes, including hydrogen and carbon, are incorporated into drug molecules to assist in quantitation during drug development. Deuteration is notable for its potential influence on the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Functions as an internal standard for quantitative analysis
- Supports NMR, GC-MS, and LC-MS applications
- Incorporates stable heavy isotopes for quantitation in drug development
- Affects pharmacokinetic and metabolic profiles of drugs
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![eMolecules 138775-03-8 | (S)-N-1-Boc-N-4-Cbz-2-piperazine carboxylic acid | Combi-Blocks | MFCD02179111 | 364.398 | C18H24N2O6 | 97.000 | CC(C)(C)OC(=O)N1CCN(C[C@H]1C(O)=O)C(=O)OCc1ccccc1 | 1g | 267166680](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000216318.jpg-250.jpg)
eMolecules 138775-03-8 | (S)-N-1-Boc-N-4-Cbz-2-piperazine carboxylic acid | Combi-Blocks | MFCD02179111 | 364.398 | C18H24N2O6 | 97.000 | CC(C)(C)OC(=O)N1CCN(C[C@H]1C(O)=O)C(=O)OCc1ccccc1 | 1g | 267166680
(S)-N-1-Boc-N-4-Cbz-2-piperazine carboxylic acid | Combi-Blocks | 138775-03-8 | MFCD02179111 | 364.398 | C18H24N2O6 | 97.000 | CC(C)(C)OC(=O)N1CCN(C[C@H]1C(O)=O)C(=O)OCc1ccccc1 | 1g | 267166680
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Medchemexpress LLC (Rac)-TTA-P2 | 918430-49-6 | 98.7% | C21H29Cl2FN2O2 | 5 MG
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(Rac)-TTA-P2 is an isomer of TTA-P2 and can be utilized as an experimental control. TTA-P2 is a potent inhibitor of the T-Type calcium channel, effectively penetrating the CNS and blocking native T-type currents in deep cerebellar nuclear neurons. It completely abolishes the window current for both wild-type and mutant Cav3.1 channels, making it suitable for research related to neurological diseases.
- Isomer of TTA-P2
- Experimental control
- Potent inhibitor of T-Type calcium channel
- Penetrates CNS well
- Blocks native T-type currents in deep cerebellar nuclear neurons
- Abolishes window current for wild-type and mutant Cav3.1 channels
- Potential for research in neurology diseases
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Medchemexpress LLC (Rac)-Idroxioleic acid (2-hydroxyoleic acid) | 56472-29-8 | 99.9% | 25 MG
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(Rac)-Idroxioleic acid (2-Hydroxyoleic acid) is a synthetic oleic acid (OA) derivative. It functions by binding to the plasma membrane and altering lipid organization. This compound has demonstrated anti-tumor effects.
- Binds to the plasma membrane and alters lipid organization.
- Exhibits anti-tumor effects.
- Impairs Jurkat cell growth in a time- and concentration-dependent manner (IC50 of approximately 40 μM).
- Induces proteolytic cleavage of PARP, a molecular marker of apoptosis.
- Significantly inhibits tumor growth in nude mice in a xenograft model.
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Medchemexpress LLC (Rac)-Cemsidomide | 2504233-68-3 | 98.5% | C28H27N3O4 | 1 ML
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(Rac)-Cemsidomide ((Rac)-CFT7455) is the racemate of Cemsidomide (HY-144841) with antitumor activity. Cemsidomide is a ubiquitin ligase pathway Ikaros/Aiolos degrader with molecular glue activity. It has an IC50 of 0.05 nM for NCIH929.1 cells.
- Antitumor activity
- Ubiquitin ligase pathway Ikaros/Aiolos degrader
- Molecular glue activity
- Targets Ikaros and Aiolos
- For research use only
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Accela Chembio Inc (r)-(-)-n-boc-3-pyrrolidinol | 5g | 109431-87-0 | MFCD01317838 | 97+% | Shelf Life: 900 Days | Light Sensitive/+4
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(r)-(-)-n-boc-3-pyrrolidinol | 5g | 109431-87-0 | MFCD01317838 | 97+% | Shelf Life: 900 Days | Light Sensitive/+4
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Medchemexpress LLC Azido-mono-amide-DOTA | 1227407-76-2 | 100.0% | 486.52 g/mol | C19H34N8O7 | 50 MG
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Azido-mono-amide-DOTA is a macrocyclic DOTA derivative that functions as a bifunctional chelator for conjugation of peptides and radionuclides. It features an azido handle for click-chemistry attachment and is intended for use in tumor pre-targeting and radiolabeling workflows.
- Bifunctional DOTA chelator for stable metal coordination.
- Azido functional group enables efficient click chemistry conjugation to biomolecules.
- High reported purity suitable for research and preclinical studies.
- Available in small milligram quantities for method development and labeling.
- Molecular weight 486.52, formula C19H34N8O7, CAS 1227407-76-2.
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eMolecules 885270-31-5 | 1-Cbz-3-(Boc-amino)-piperidine-3-carboxylic acid | Acrotein ChemBio Inc. | MFCD04114485 | 378.425 | C19H26N2O6 | 97.000 | CC(C)(C)OC(=O)NC1(CCCN(C1)C(=O)OCc1ccccc1)C(O)=O | 0.5g | 625591694
1-Cbz-3-(Boc-amino)-piperidine-3-carboxylic acid | Acrotein ChemBio Inc. | 885270-31-5 | MFCD04114485 | 378.425 | C19H26N2O6 | 97.000 | CC(C)(C)OC(=O)NC1(CCCN(C1)C(=O)OCc1ccccc1)C(O)=O | 0.5g | 625591694
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eMolecules 98327-87-8 | (Rac)-BINAP | ChemScene | MFCD00010805 | 622.688 | C44H32P2 | 98.000 | c1ccc(cc1)P(c1ccccc1)c1ccc2ccccc2c1-c1c(ccc2ccccc12)P(c1ccccc1)c1ccccc1 | 25g | 536853813
(Rac)-BINAP | ChemScene | 98327-87-8 | MFCD00010805 | 622.688 | C44H32P2 | 98.000 | c1ccc(cc1)P(c1ccccc1)c1ccc2ccccc2c1-c1c(ccc2ccccc12)P(c1ccccc1)c1ccccc1 | 25g | 536853813
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Medchemexpress LLC (Rac)-bio8898 | 402564-79-8 | 98.0% | 10 MG
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(Rac)-BIO8898 is a synthetic small-molecule inhibitor of the CD40-CD154 (CD40L) protein-protein interaction, reported to inhibit soluble CD40L binding to CD40-Ig with an IC50 of approximately 25 μM. Supplied as a high-purity solid for research use.
- Inhibits CD40-CD154 interaction; IC50 ≈ 25 μM.
- Chemical formula C53H64N8O6; molecular weight 909.13 g·mol⁻1.
- High purity (98.03%) suitable for biochemical and cell-based assays.
- Available in small research sizes; soluble in DMSO.
- For research use only; not for human or diagnostic use.
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Medchemexpress LLC (Rac)-Rotigotine hydrochloride | 102120-99-0 | C19H26ClNOS | 5 MG
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(Rac)-Rotigotine hydrochloride is a racemate of Rotigotine, functioning as a full agonist of the dopamine receptor, a partial agonist of the 5-HT1A receptor, and an antagonist of the α2B-adrenergic receptor. It is primarily utilized in research contexts, especially for studies related to Parkinson's disease.
- Functions as a full agonist at dopamine receptors
- Acts as a partial agonist at the 5-HT1A receptor
- Serves as an antagonist at the alpha-2B adrenergic receptor
- Shows selectivity for D3 receptors over D2, D4, D5, and D1 receptors
- Provides protection for dopaminergic neurons against MPP+ toxicity
- Significantly inhibits ROS production caused by rotenone
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Medchemexpress LLC Azido-mono-amide-DOTA | 1227407-76-2 | 100.0% | 486.52 g·mol⁻¹ | C19H34N8O7 | 10 MG
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Azido-mono-amide-DOTA is an azide-functional DOTA derivative that acts as a bifunctional chelator for radiolabeling and bioconjugation. It combines a macrocyclic chelator for stable metal coordination with an azide handle for click chemistry, making it suitable for assembling radiopharmaceuticals and imaging probes in research settings.
- Azide functionality enables copper-free or copper-catalyzed click conjugation.
- Macrocyclic DOTA scaffold provides strong chelation of radiometals.
- High reported purity (99.96%) suitable for research applications.
- Compact molecular weight and defined chemical formula aid analytical characterization.
- Commonly supplied in small milligram quantities for synthesis and labeling workflows.
- CAS number 1227407-76-2 for unambiguous substance identification.
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![eMolecules 5211-23-4 | (S)-1-Benzyl 2-methyl pyrrolidine-1,2-dicarboxylate | AA Blocks LLC | MFCD00134246 | 263.293 | C14H17NO4 | 0.000 | COC(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1 | 10g | 433198299](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000169701.jpg-250.jpg)
eMolecules 5211-23-4 | (S)-1-Benzyl 2-methyl pyrrolidine-1,2-dicarboxylate | AA Blocks LLC | MFCD00134246 | 263.293 | C14H17NO4 | 0.000 | COC(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1 | 10g | 433198299
(S)-1-Benzyl 2-methyl pyrrolidine-1,2-dicarboxylate | AA Blocks LLC | 5211-23-4 | MFCD00134246 | 263.293 | C14H17NO4 | 0.000 | COC(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1 | 10g | 433198299
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![Medchemexpress LLC 4-Quinolinemethanol, 6,8-dichloro-α-2-piperidinyl-2-tricyclo[3.3.1.13,7]dec-1-yl- | 785718-37-8 | 98.6% | 445.42 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000385141-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 4-Quinolinemethanol, 6,8-dichloro-α-2-piperidinyl-2-tricyclo[3.3.1.13,7]dec-1-yl- | 785718-37-8 | 98.6% | 445.42 | 50 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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NSC305787 is an inhibitor of ezrin with a Kd of 5.85 μM. It inhibits the phosphorylation of ezrin caused by PKCΙ with an IC50 of 8.3 μM, and exhibits antitumor activity. NSC305787 also inhibits PKCΙ phosphorylation of Moesin, Radixin, and MBP. It primarily inhibits ezrin T567 phosphorylation through binding to ezrin rather than by inhibiting PKCΙ kinase activity.
- Inhibitor of ezrin with a Kd of 5.85 μM
- Inhibits phosphorylation of ezrin caused by PKCΙ with an IC50 of 8.3 μM
- Exhibits antitumor activity
- Inhibits PKCΙ phosphorylation of Moesin, Radixin, and MBP
- Primarily inhibits ezrin T567 phosphorylation by binding to ezrin
- Shows inhibitory activity against ezrin-mediated invasion of K7M2 osteosarcoma (OS) cells
- Reduces cell motility phenotypes in zebrafish
- Blocks OS metastatic growth in lung organ culture
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Medchemexpress LLC (R)-pyrrolidine-2-carboxylic acid | 344-25-2 | ≥98.0% | C5H9NO2 | 1 G
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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(R)-pyrrolidine-2-carboxylic acid is a proline isomer known to exhibit high renal and hepatotoxicity in rats. It can be utilized for studying amino acid metabolism and toxicity mechanisms.
- Purity of ≥98.0%
- Appears as a white to off-white solid
- Soluble in water (25 mg/mL) and DMSO (2.78 mg/mL)
- Molecular weight of 115.13
- Suitable for research use only
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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