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Filtered Search Results
Medchemexpress LLC N-Arachidonyl maleimide | 876305-42-9 | 98.31% | 369.54 | 25 MG
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N-Arachidonyl maleimide is a potent, irreversible inhibitor of monoacylglycerol lipase (MAGL) with an IC50 value of 140 nM. It can be used to modulate the effects of 2-arachidonyl glycerol (2-AG) by increasing its endogenous levels in the brain, and it prevents cerebellar membrane-mediated degradation of 2-AG.
- Potent, irreversible MAGL inhibitor
- Modulates effects of 2-arachidonyl glycerol (2-AG)
- Increases endogenous levels of 2-AG in the brain
- Prevents cerebellar membrane-mediated degradation of 2-AG
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Medchemexpress LLC Bisindolylmaleimide II | 137592-45-1 | MFCD00236430 | 99.8% | 438.52 | C27H26N4O2 | 5 MG
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Bisindolylmaleimide II is a small-molecule inhibitor used to block protein kinase C (PKC) activity in biochemical and cellular research. Supplied as a solid with high stated purity and DMSO solubility, it is commonly used to probe PKC-dependent signaling and to evaluate kinase-related pathways in vitro.
- General inhibitor of protein kinase C subtypes.
- High purity for research applications.
- Solid form facilitates accurate weighing and storage.
- Soluble in DMSO for solution preparation.
- Suitable for biochemical and cellular PKC assays.
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Medchemexpress LLC Bisindolylmaleimide I | 133052-90-1 | 412.48 | 25 MG
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Bisindolylmaleimide I (GF109203X) is a cell-permeable and reversible protein kinase C (PKC) inhibitor. It exhibits IC50 values of 20 nM for PKCα, 17 nM for PKCβI, 16 nM for PKCβII, and 20 nM for PKCγ. This compound also functions as a glycogen synthase kinase-3 (GSK-3) inhibitor.
- Cell-permeable and reversible protein kinase C inhibitor
- Inhibits PKCα, PKCβI, PKCβII, and PKCγ with high potency
- Functions as a GSK-3 inhibitor
- Applicable in metabolic disease research
- Applicable in cancer research
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Medchemexpress LLC Cy5 maleimide | 1437796-65-0 | 98.0% | 641.24 | 25 MG
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Cy5 maleimide is a CY dye, a type of cyanine compound. Cyanine compounds are characterized by having two nitrogen atoms connected by an odd number of methyl units. These dyes possess long wavelengths, adjustable absorption and emission, high extinction coefficients, good water solubility, and relatively simple synthesis. CY dyes are frequently used for labeling proteins, antibodies, and small molecular compounds. For protein and antibody labeling, the conjugation can be achieved through a simple mixing reaction.
- Possesses long wavelengths
- Adjustable absorption and emission
- High extinction coefficients
- Good water solubility
- Relatively simple synthesis
- Used for labeling proteins, antibodies, and small molecular compounds
- Conjugation for protein and antibody labeling can be achieved through simple mixing reaction
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Advanced Chemblocks Inc 1-(2-AMINOETHYL)-2,5-DIHYDR 1G
1-(2-AMINOETHYL)-2,5-DIHYDRO-1H-PYRROLE-2,5-DIONE HYDROCHLORIDE
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Medchemexpress LLC Ruboxistaurin | 169939-94-0 | 99.5% | 468.55 g/mol | C28H28N4O3 | 100 MG
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Ruboxistaurin is a selective, orally active protein kinase C beta (PKCβ) inhibitor for preclinical research into PKCβ-related signaling and diabetic vascular complications. It is provided as a solid and as a DMSO solution, and is characterized by defined physicochemical properties and high purity to support reproducible experimental work.
- Selective PKCβ inhibition for targeted signaling studies.
- High purity (99.5%) supporting reliable experimental results.
- Well-characterized molecular properties (C28H28N4O3; 468.55 g/mol).
- Available in multiple formats and pack sizes for flexible experimental needs.
- CAS registry linkage for unambiguous compound identification.
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Enzo Life Sciences Bisindolylmaleimide V (5mg). CAS: 113963-68-1
Negative control for the protein kinase C (PKC)-inhibitory activity. Formula: C21H15N3O2. MW: 341.4. Purity: ≥98%. Solubility: Soluble in DMSO or methanol; very slightly soluble in 100% ethanol. Long Term Storage: -20°C.
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![Medchemexpress LLC 1H-Pyrrole-2,5-dione, 1-(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)- | 75350-46-8 | 99.5% | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000413542-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 1H-Pyrrole-2,5-dione, 1-(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)- | 75350-46-8 | 99.5% | 25 MG
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Fluorescein-5-maleimide is a fluorescent dye used to detect the redox state of thiols in eukaryotic cells. It can label peptides, detect negatively charged nanoparticles, and label actin to explore its interaction with cardiac myosin-binding protein C (cMyBP-C) for heart failure research. It can also screen mutant proteins containing cysteine residues. The excitation wavelength is 494 nm, and the emission wavelength is 519 nm.
- Fluorescent dye
- Detects the redox state of thiols in eukaryotic cells
- Labels peptides
- Detects negatively charged nanoparticles
- Labels actin to study interaction with cardiac myosin-binding protein C (cMyBP-C)
- Screens mutant proteins containing cysteine residues
- Excitation wavelength: 494 nm
- Emission wavelength: 519 nm
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Medchemexpress LLC N-Arachidonyl maleimide | 876305-42-9 | 98.3% | 369.54 | 1 ML
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N-Arachidonyl maleimide is a potent, irreversible inhibitor of monoacylglycerol lipase (MAGL) with an IC50 value of 140 nM. It modulates the effects of 2-arachidonyl glycerol (2-AG) by increasing its endogenous levels in the brain and preventing cerebellar membrane-mediated degradation.
- Potent and irreversible monoacylglycerol lipase (MAGL) inhibitor
- Modulates effects of 2-arachidonyl glycerol (2-AG)
- Increases endogenous levels of 2-AG in the brain
- Prevents cerebellar membrane-mediated degradation of 2-AG
- Induces hypothermia, antinociception, and catalepsy in vivo when combined with 2-AG
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Medchemexpress LLC Bcn-endo-PEG7-maleimide | 95.0% | 695.80 g/mol | C34H53N3O12 | 10 MG
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BCN-endo-PEG7-maleimide is a BCN-based click chemistry linker containing a seven-unit polyethylene glycol (PEG7) spacer and a terminal maleimide for selective thiol conjugation. It is designed for bioconjugation, antibody-drug conjugate linker assembly, and other strain-promoted click chemistry applications.
- Contains an endo-BCN moiety for strain-promoted click reactions.
- Includes a PEG7 spacer to improve solubility and flexibility.
- Has a terminal maleimide for selective conjugation to thiol groups.
- Suitable for bioconjugation and antibody-drug conjugate linker synthesis.
- Offered in small-scale research pack sizes for discovery workflows.
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eMolecules 7423-55-4 | 3-Maleimidopropionic acid | Ambeed | MFCD00043030 | 169.136 | C7H7NO4 | 95 | OC(=O)CCN1C(=O)C=CC1=O | 10g | 525008566
3-Maleimidopropionic acid | Ambeed | 7423-55-4 | MFCD00043030 | 169.136 | C7H7NO4 | 95.000 | OC(=O)CCN1C(=O)C=CC1=O | 10g | 525008566
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Medchemexpress LLC Cyanine5 maleimide | 1437796-65-0 | MFCD28385511 | 99.4% | 641.24 g/mol | C38H45ClN4O3 | 5 MG
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Cy5 maleimide is a thiol-reactive Cyanine5 fluorescent dye that selectively labels cysteine residues via a stable thioether linkage. It produces bright, long-wavelength fluorescence suitable for fluorescence imaging and detection, and is supplied as a high-purity reagent for research applications.
- Thiol-reactive maleimide group for selective cysteine conjugation.
- Bright, long-wavelength fluorescence ideal for imaging (approx. 648/671 nm).
- Forms a stable thioether linkage for durable labeling.
- High purity suitable for sensitive assays (≈99.4%).
- Soluble in common organic solvents such as DMSO and DMF.
- Store sealed, protected from moisture and light at -20°C.
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Medchemexpress LLC Bisindolylmaleimide 100mg | 119139-23-0 | 100MG
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Bisindolylmaleimide IV (Arcyriarubin A) is a potent protein kinase C (PKC) inhibitor with IC50s ranging from 0 1 to 0 55 M Bisindolylmaleimide IV also inhibits PKA (IC50 3 1-11 8 M)[1 Bisindolylmaleimide IV is a potent selective inhibitor of human cytomegalovirus (HCMV) replication in cell culture with an IC50 of 0 2 M[2
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eMolecules 2021179-11-1 | Medchem Express | MMAE-SMCC | 1mg | 694125024 | HY-135660 | 1140.45 | C58H89N7O14S
Ambeed | Sodium ((2R3S4R5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-34-dihydroxytetrahydrofuran-2-yl)methyl dihydrogentriphosphate | 1g | 490497503 | A117222 | 36051-68-0 | MFCD00078193 | 527.119 | C9H14N3Na2O14P3
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Medchemexpress LLC Sulfo-Cy3 maleimide potassium | 1656990-68-9 | 93.35% | 776.96 | 1 MG
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Sulfo-Cy3 maleimide potassium is a fluorescent dye featuring a maleimide functionality at the end of a short alkyl linker. It can be utilized for labeling antibodies and other labile proteins.
- Fluorescent dye
- Maleimide functionality
- Used for labeling antibodies
- Used for labeling labile proteins
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