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Filtered Search Results
Chemscene CHEMSCENE
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5000580146 HYDROQUINIDINE 100G
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Medchemexpress LLC Glucocorticoid receptor modulator 1 | 2868357-11-1 | C24H23ClN2O4S | 200 MG
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Glucocorticoid receptor modulator 1 is a highly potent and orally active non-steroidal selective glucocorticoid receptor modulator. It has an IC50 value of 9 nM for NF-κB and 130 nM for AP-1. This product can effectively reduce the expression of inflammatory factors such as IL-6, IL-1β, and TNF-α, and can also relieve dermatitis in mice.
- Highly potent and orally active.
- Non-steroidal selective glucocorticoid receptor modulator.
- Inhibits NF-κB and AP-1 pathways.
- Reduces the expression of inflammatory factors like IL-6, IL-1β, and TNF-α.
- Relieves dermatitis in mice.
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Apexbio Technology LLC ML 281 200mg
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ML 281 (CAS 1404437-62-2) is a small-molecule inhibitor targeting serine/threonine kinase STK33 It is designed to block the phosphorylation activity of STK33 thereby interfering with downstream signaling pathways regulated by STK33-mediated phosphorylation events ML 281 exerts its biological activity primarily through selective inhibition of STK33 kinase activity In biochemical assays ML 281 demonstrates potent inhibitory effects with an IC50 value of approximately 14 nM against STK33 Based on these pharmacological properties ML 281 holds research potential in investigating the biological role of STK33 in tumor cell survival cellular proliferation and oncogenic signal transduction pathways
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Chemscene CHEMSCENE
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5000580031 1-BROMOISOQUINOLINE 1G
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TARGETMOL CHEMICALS INC Desloratadine 200MG
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Also available in 1 g, 1 mL, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Desloratadine (Sch34117) is a long-acting piperidine derivate with selective H1 antihistaminergic and non-sedating properties. Desloratadine diminishes the typical histaminergic effects on H1-receptors in bronchial smooth muscle, capillaries and gastrointestinal smooth muscle, including vasodilation, bronchoconstriction, increased vascular permeability, pain, itching and spasmodic contractions of gastrointestinal smooth muscle. Desloratadine is used to provide symptomatic relieve of allergic symptoms. Purity 100%
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eMolecules 1952360-91-6 | (Fmoc-amino)-PEG12-C2-carboxylic acid | Chem-Impex | MFCD08064302 | 839.973 | C42H65NO16 | 98.000 | OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 5g | 686069703
(Fmoc-amino)-PEG12-C2-carboxylic acid | Chem-Impex | 1952360-91-6 | MFCD08064302 | 839.973 | C42H65NO16 | 98.000 | OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 5g | 686069703
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eMolecules 54013-06-8 | 5-Amino-pyrazine-2-carboxylic acid ethyl ester | J&W PharmLab LLC | MFCD08437665 | 167.168 | C7H9N3O2 | 96.000 | CCOC(=O)c1cnc(N)cn1 | 500mg | 571064491
5-Amino-pyrazine-2-carboxylic acid ethyl ester | J&W PharmLab LLC | 54013-06-8 | MFCD08437665 | 167.168 | C7H9N3O2 | 96.000 | CCOC(=O)c1cnc(N)cn1 | 500mg | 571064491
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Ambeed AMBEED
5000869182 4-METHOXYTHIOPHENE-3-CARBO 1GR
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eMolecules 90905-32-1 | 2-methoxypyrimidine-5-carbaldehyde | Combi-Blocks | MFCD03446732 | 138.126 | C6H6N2O2 | 98.000 | COc1ncc(C=O)cn1 | 1g | 232303734
2-methoxypyrimidine-5-carbaldehyde | Combi-Blocks | 90905-32-1 | MFCD03446732 | 138.126 | C6H6N2O2 | 98.000 | COc1ncc(C=O)cn1 | 1g | 232303734
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eMolecules 7,8-DIHYDROQUINOLINE-2,5(1H,6H)-DIONE | 15450-69-8 | MFCD00766821 | 5g
AstaTech | 7,8-DIHYDROQUINOLINE-2,5(1H,6H)-DIONE | 5g | 443836014 | 81092 | 95.000 | 15450-69-8 | MFCD00766821 | 163.176 | C9H9NO2
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TARGETMOL CHEMICALS INC Bosutinib 200MG
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Also available in 1 mL, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Bosutinib (SKI-606) is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl (IC50 1 nM) and Src (IC50 1.2 nM) kinases. Purity 99.84%
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Apexbio Technology LLC Amsacrine 51264-14-3 200mg
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Amsacrine (CAS 51264-14-3) also known as m-AMSA is a small-molecule inhibitor of DNA topoisomerase II It is widely used as an antineoplastic agent in biomedical research particularly for investigating the treatment of lymphomas and acute leukemias Amsacrine exhibits cytotoxic effects across various cancer cell lines with reported IC50 values of 190 2 27 4 ng/ml 46 1 3 9 ng/ml and 22 6 3 1 ng/ml in HT1376 RT112 and RT4 bladder cancer cells and 11 8 2 0 ng/ml 5 0 0 4 ng/ml and 11 7 1 5 ng/ml in the 833K Susa and GH testicular cancer cell lines respectively Testicular cancer cell lines display greater sensitivity to Amsacrine-induced inhibition than bladder cancer cell lines This compound is valuable for studying DNA damage mechanisms and the cellular response to topoisomerase II inhibition
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Ambeed AMBEED
5000869270 2-ETHOXYPYRIMIDIN-5-AMINE 1GR
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000656183 AF488 AMINE 5MG
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TARGETMOL CHEMICALS INC Pinocembrin 7-O-3 -O-galloyl-4
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Also available in 1 mg, 10 mg and bulk. Please contact Fisher for quotes. Pinocembrin 7-O-[3''-O-galloyl-4'',6''-hexahydroxydiphenoyl]-beta-D-glucoside can moderately inhibit alpha-amylase activity, with an IC50 value of 0.03 µmol/ml. Purity 98.73%
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