Quinolines and derivatives
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Filtered Search Results
Medchemexpress LLC HCV-IN-31 | 1998705-62-6 | 99.7% | 312.30 | 25 MG
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HCV-IN-31 (compound 4) is a potent inhibitor of the Hepatitis C Virus (HCV) replicon, demonstrating an EC50/EC95 of 15.7 μM. This compound is provided as a white to off-white solid, suitable for various research applications.
- High purity of 99.7%
- Molecular weight: 312.30
- Molecular formula: C12H17FN6O3
- CAS number: 1998705-62-6
- Recommended storage: 4°C, protect from light
- In solvent storage: -80°C for 6 months, -20°C for 1 month (protect from light)
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Medchemexpress LLC Pyrroloquinoline quinone disodium salt | 122628-50-6 | 98.0% | 374.17 g/mol | C14H4N2Na2O8 | 50 MG
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Pyrroloquinoline quinone disodium salt is the disodium salt form of the redox cofactor PQQ supplied for research and analytical applications. The material is a pink to red solid used in studies of metabolism, oxidative stress, and cellular signaling. It is provided as a small powdered reagent with recommended sealed storage to preserve stability.
- Redox co-factor used in metabolic and oxidative stress research.
- High purity suitable for analytical and biological applications.
- Pink to red solid that is easy to weigh and handle.
- Stable when stored sealed and protected from moisture.
- Available in small powder pack sizes for laboratory use.
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Medchemexpress LLC Pyrroloquinoline quinone-13C3 sodium | 72909-34-3 | 99.3% | 421.11 g·mol⁻¹ | C1113C3H2N2Na4O8 | 1 MG
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Pyrroloquinoline quinone-13C3 sodium is the 13C3 isotopically labeled sodium salt of pyrroloquinoline quinone, supplied as a high-purity tracer and internal standard for quantitative analytical methods. It is intended for research use in studies of redox chemistry and biological activity, and for method development and validation in mass spectrometry and NMR-based assays.
- Isotopically labeled sodium salt for tracer and internal standard use.
- High purity suitable for quantitative analytical methods.
- Compatible with NMR, GC-MS, and LC-MS workflows.
- Supports studies of redox activity and biological function.
- Supplied in small, weighed quantities for research applications.
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Ambeed Benzofuran2 3H one
Benzofuran-2(3H)-one, 553-86-6, 98%
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Medchemexpress LLC 5'-O-(4,4'-Dimethoxytrityl)-5-methoxyuridine | 2095417-73-3 | C31H32N2O9 | 50 MG
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5'-O-(4,4'-Dimethoxytrityl)-5-methoxyuridine is a purine nucleoside analog. This chemical compound is known for its broad antitumor activity, particularly targeting indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and induction of apoptosis, making it a subject of interest in cancer research.
- Purine nucleoside analog
- Exhibits broad antitumor activity
- Targets indolent lymphoid malignancies
- Inhibits DNA synthesis
- Induces apoptosis
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Medchemexpress LLC 5'-O-(4,4'-dimethoxytrityl)-2'-O-methyluridine | 103285-22-9 | 98.0% | 560.59 g/mol | C31H32N2O8 | 1 G
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5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyluridine is a DMT-protected uridine nucleoside analog with a 2'-O-methyl ribose modification, used as an intermediate in the chemical synthesis of modified oligonucleotides and nucleoside derivatives. Molecular formula C31H32N2O8; molecular weight 560.59 g/mol. Follow supplier storage recommendations for long-term stability.
- DMT-protected at the 5'-position for controlled deprotection.
- 2'-O-methyl modification enhances nuclease resistance.
- Designed for incorporation into synthetic oligonucleotides.
- High purity (98.0%) suitable for research applications.
- Stable as a powder under recommended storage conditions.
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Medchemexpress LLC 7-Methylisatin | 1127-59-9 | 161.16 | 10 G
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7-Methylisatin is a derivative of Isatin and can be utilized as a molecular block for biochemical assay reagents.
- Derivative of Isatin
- Can be utilized as a molecular block
- For research use only
- Store at room temperature for 3 years; in solvent, -80°C for 2 years; -20°C for 1 year
- Soluble in DMSO
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eMolecules 889958-08-1 | 6-PIPERAZIN-1-YL-4(3H)-QUINAZOLINONE-3-ACETIC ACID | AstaTech | MFCD06796710 | 288.307 | C14H16N4O3 | 97.000 | OC(=O)Cn1cnc2ccc(cc2c1=O)N1CCNCC1 | 1g | 112528797
6-PIPERAZIN-1-YL-4(3H)-QUINAZOLINONE-3-ACETIC ACID | AstaTech | 889958-08-1 | MFCD06796710 | 288.307 | C14H16N4O3 | 97.000 | OC(=O)Cn1cnc2ccc(cc2c1=O)N1CCNCC1 | 1g | 112528797
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Medchemexpress LLC 7-Deazahypoxanthine | 3680-71-5 | 99.9% | C6H5N3O | 25 G
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7-Deazahypoxanthine is a biochemical reagent designed for life science research. It can be used as a biological material or organic compound, and serves as a pharmaceutical intermediate. Its methylated forms are utilized as regiochemical probes of xanthine oxidase.
- Biochemical reagent for life science research
- Suitable as a biological material or organic compound
- Serves as a pharmaceutical intermediate
- Methylated forms act as regiochemical probes for xanthine oxidase
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Medchemexpress LLC BSJ-03-204 (triTFA) | 99.9% | 1174.97 | 25 MG
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BSJ-03-204 triTFA is a PROTAC connected by ligands for Cereblon and CDK. It is a potent and selective Palbociclib-based CDK4/6 dual degrader, with IC50s of 26.9 nM for CDK4/D1 and 10.4 nM for CDK6/D1. This compound does not induce IKZF1/3 degradation and demonstrates anti-cancer activity.
- PROTAC connected by ligands for Cereblon and CDK.
- Potent and selective Palbociclib-based CDK4/6 dual degrader.
- Demonstrates potent anti-proliferative effects on MCL cell lines.
- Induces a G1 arrest.
- Selectively degrades CDK4/6 in WT cells without affecting IKZF1/3 degradation.
- Exhibits anti-cancer activity.
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Sigma Aldrich Fine Chemicals Biosciences 4-Methylumbellferyl beta-250MG
methyl 4-Methylumbellferyl beta-250MG
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Apexbio Technology LLC IAA-94 54197-31-8 10mg
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IAA-94 (CAS 54197-31-8) is a small-molecule inhibitor of epithelial chloride channels modulating cellular electrophysiological properties by disrupting chloride ion transport Experimental studies have demonstrated that IAA-94 can interfere with interactions involving the negative factor (Nef) protein during infection indicating its capacity to modulate Nef-mediated processes Due to its specificity in targeting chloride channels IAA-94 is widely utilized in investigations of ion channel-related signaling pathways in tumor cells and serves as a valuable tool in studies of cell electrophysiology and infection mechanisms
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Medchemexpress LLC LM11A-31 5mg | 102562-74-3 | 243.35 g/mol | C12H25N3O2 | 5 MG
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LM11A-31 is a small-molecule ligand and modulator of the p75 neurotrophin receptor (p75NTR) used in preclinical research of neurodegenerative diseases. It is orally active, brain-penetrant, and provided for in vitro and in vivo studies in solid and solution formats.
- Small-molecule p75NTR modulator for neurodegeneration research.
- Orally active and brain-penetrant in preclinical studies.
- Available as a solid and as 10 mM solutions in DMSO for convenience.
- Identified by CAS 102562-74-3 and molecular formula C12H25N3O2.
- High reported purity (~99.9%) suitable for research applications.
- Commonly supplied in small research pack sizes such as 5 mg.
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Accela Chembio Inc 2-ethoxy-1-ethoxycarbonyl-1 | 2-dihydroquinoline (eedq) | 100g | 16357-59-8 | MFCD00006703 | 97+% | Shelf Life: 1260 Days | Light Sensitive/moisture Sensitive/+4
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2-ethoxy-1-ethoxycarbonyl-1 | 2-dihydroquinoline (eedq) | 100g | 16357-59-8 | MFCD00006703 | 97+% | Shelf Life: 1260 Days | Light Sensitive/moisture Sensitive/+4
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Medchemexpress LLC 4,6(1H,5H)-Pyrimidinedione, 1-(3-chloro-4-methylphenyl)-5-[3-(2-furanyl)-2-propen-1-ylidene] | 593273-05-3 | 99.2% | 372.83 | 25 MG
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DCH36_06 is a potent and selective p300/CBP inhibitor. It mediates p300/CBP inhibition, leading to hypoacetylation on H3K18 in leukemic cells, and exhibits anti-tumor activity.
- Potent and selective p300/CBP inhibitor.
- Induces apoptosis in leukemic cells.
- Arrests cell cycle at G1 phase.
- Shows potent antiproliferative activity against a range of leukemia cell lines.
- Blocks leukemic xenograft growth in mice.
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