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Filtered Search Results
Medchemexpress LLC Oxyclozanide | 2277-92-1 | 98.7% | 401.46 | 200 MG
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Oxyclozanide is an orally active salicylanilide anthelmintic agent that primarily functions by uncoupling oxidative phosphorylation in flukes. It also exhibits good anti-adenovirus, anti-biofilm, antifungal, and antibacterial activities.
- Orally active salicylanilide anthelmintic agent.
- Mainly acts by uncoupling oxidative phosphorylation in flukes.
- Shows good anti-adenovirus, anti-biofilm, antifungal, and antibacterial activity.
- Effective against meticillin-sensitive and meticillin-resistant S. pseudintermedius isolates.
- Inhibits methicillin-resistant S. aureus (MRSA).
- Demonstrates antiparasitic effectiveness in sheep and cattle.
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Medchemexpress LLC MI-773 | 1303607-07-9 | 96.3% | 562.50 | 100 MG
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MI-773 is a potent MDM2-p53 protein-protein interaction (PPI) inhibitor. It demonstrates high binding affinity against MDM2 and exhibits antitumor activity. An analog, MI-77301, shows even higher binding affinity and more pronounced antitumor activity in various p53 xenograft models.
- Potent MDM2-p53 protein-protein interaction (PPI) inhibitor.
- High binding affinity against MDM2 (Kd=8.2 nM).
- Exhibits antitumor activity.
- Analog shows enhanced binding affinity and antitumor activity.
- Effective in various p53 xenograft models including osteosarcoma, human prostate, melanoma, colorectal tumor, and human acute lymphoblastic leukemia.
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Medchemexpress LLC Purvalanol B (NG 95) | 212844-54-7 | 97.0% | 432.90 | 200 MG
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Purvalanol B (NG 95) is a potent, selective, reversible, and ATP-competitive inhibitor of cyclin-dependent kinases (CDK). It demonstrates significant selectivity for CDK over other protein kinases and effectively inhibits the growth of a chloroquine-resistant strain of *P. falciparum*.
- Potent, selective, reversible, and ATP-competitive inhibitor of CDK
- Inhibits cdc2-cyclin B, CDK2-cyclin A, and CDK5-p35 with IC50s of 6 nM
- Inhibits CDK2-cyclin E with an IC50 of 9 nM
- Shows selectivity for CDK over other protein kinases (IC50 > 1000 nM)
- Inhibits the growth of a chloroquine-resistant strain of *P. falciparum*
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Medchemexpress LLC 2,5-Cyclohexadiene-1,4-dione, 2,5-bis[(2-methylphenyl)amino]- | 252950-56-4 | 99.7% | 318.37 | 50 MG
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DTPD-Q is a transformation product of the tire additive N,N′-diphenyl-p-phenylenediamine (DTPD). It accumulates and increases ecological risk in the environment. This product is intended for research use only and is not sold to patients.
- Transformation product of a common tire additive.
- Accumulates and raises ecological risk in the environment.
- High purity of 99.68%.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000387896 1-NAPHTHALENEACETIC 200MG
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Medchemexpress LLC Benzeneacetonitrile, 4-[(4-methoxyphenyl)methoxy]- | 175135-47-4 | 98.1% | 253.30 | 200 MG
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O4I1 is a potent Oct3/4 inducer that enhances Oct3/4 gene expression, increases Oct3/4 protein levels, and promotes Oct3/4 mediated transcriptional activation. It activates Oct3/4 at both transcriptional and translational levels in various human cell lines and is sufficient to enhance Oct3/4 overexpression by 2-fold and 3-fold after 48 and 72 hours of treatment, respectively.
- Potent Oct3/4 inducer.
- Enhances Oct3/4 gene expression.
- Increases Oct3/4 protein levels.
- Promotes Oct3/4 mediated transcriptional activation.
- Activates Oct3/4 at transcriptional and translational levels in diverse human cell lines.
- Can enhance Oct3/4 overexpression 2-fold and 3-fold after 48 and 72 hours of treatment in untransfected HEK293 cells.
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Medchemexpress LLC 10-Deacetylbaccatin III | 32981-86-5 | 99.79% | 544.59 | 200 MG
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10-Deacetylbaccatin III (Standard) is the analytical standard of 10-Deacetylbaccatin III, intended for research and analytical applications. It is commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Grade of analytical standard.
- Reference standard supplied assay.
- Commonly used in HPLC, GC, and MS research experiments.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000377764 X-GAL 200MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000377781 ENTOSPLETINIB 200MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000377963 SF1670 200MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000378098 CAPRYLOCAPROYL MACRO 200MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000378146 ORN 06 SODIUM 1MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000379141 AMINO-PEG13-AMINE 1G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000378567 AP-III-A4 200MG
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Medchemexpress LLC DC-BPi-03 | 2758411-46-8 | C14H14N4O2S | 25 MG
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DC-BPi-03 is a potent BPTF-BRD inhibitor with an IC50 of 698.3 nM and a Kd of 2.81 μM. It is intended for research use only and is not for sale to patients.
- Potent BPTF-BRD inhibitor
- Inhibits BPTF-BRD with an IC50 of 698.3 nM
- Inhibits BPTF-BRD with a Kd of 2.81 μM
- For research use only
- Relevant to cancer research
- Relevant to blood or cardio-cerebrovascular disease research
- Relevant to blood disease research
- Relevant to leukemia/lymphoma/myeloma research
- Relevant to cancer targeted therapy
- Relevant to cancer metabolism and metastasis
- Acts as an epigenetic reader domain inhibitor
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