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Filtered Search Results
Medchemexpress LLC Prostaglandin H2 (PGH2) | 42935-17-1 | ≥95.0% | 352.47 | 10 UG
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Prostaglandin H2 (PGH2) is an endothelium-derived contracting factor that can cause vasoconstriction. It is the common precursor of all prostaglandins and is produced by several cells that express cyclooxygenases. PGH2 can activate PGD2 receptors CRTH2 and DP by interacting directly with the receptors or by giving rise to PGD2 after catalytic conversion by plasma proteins. It is used in research for inflammation and neurological diseases, such as Alzheimer's disease.
- Increases forward-scatter of eosinophils
- Induces shape changes and Ca2+ production in eosinophils
- Induces migration and collagen-induced platelet aggregation in eosinophils
- Inhibits eosinophil degranulation by activation of CRTH2 receptors
- Accelerates the rate of formation of dimers and higher oligomers of amyloid β1-42
- Induces contraction of rabbit pulmonary artery
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Apexbio Technology LLC MK-8245 1030612-90-8 200mg
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MK-8245 (CAS 1030612-90-8) is a potent liver-selective small molecule inhibitor of stearoyl-CoA desaturase (SCD) SCD1 catalyzes fatty acid desaturation and represents a target for treating type II diabetes obesity dyslipidemia and other metabolic disorders MK-8245 demonstrates strong inhibitory activity against rat mouse and human SCD1 with an IC50 of approximately 1 nM and displays liver-specific tissue distribution mediated by organic anion transporting polypeptides (OATPs) Animal studies revealed MK-8245 reduces blood glucose levels and hepatic triglycerides dose-dependently supporting its application in metabolic disease research
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eMolecules 500769-35-7 | 8-Fluoro-4-hydroxyquinolin-2(1H)-one | MFCD13179430 | 250mg
Ambeed | 8-Fluoro-4-hydroxyquinolin-2(1H)-one | 250mg | 600837075 | A307471 | 500769-35-7 | MFCD13179430 | 179.150 | C9H6FNO2
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eMolecules 58794-09-5 | 7-Bromoisoquinoline | Apollo Scientific - Building Blocks | MFCD07368661 | 208.058 | C9H6BrN | 95.000 | Brc1ccc2ccncc2c1 | 250mg | 553346418
7-Bromoisoquinoline | Apollo Scientific - Building Blocks | 58794-09-5 | MFCD07368661 | 208.058 | C9H6BrN | 95.000 | Brc1ccc2ccncc2c1 | 250mg | 553346418
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eMolecules 2246-44-8 | 2-Methylnaphthalen-1-amine | ChemScene | MFCD00059135 | 157.216 | C11H11N | 98.000 | Cc1ccc2ccccc2c1N | 5g | 694123000
2-Methylnaphthalen-1-amine | ChemScene | 2246-44-8 | MFCD00059135 | 157.216 | C11H11N | 98.000 | Cc1ccc2ccccc2c1N | 5g | 694123000
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Apexbio Technology LLC Fingolimod (FTY720) 162359-56-0 200mg
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Fingolimod (FTY720 CAS 162359-56-0) is an orally administered sphingosine-1-phosphate (S1P) receptor agonist structurally analogous to natural sphingosine Originally derived from fungal metabolites and initially investigated in organ transplantation fingolimod interacts potently with receptors S1P1 S1P3 S1P4 and S1P5 (EC50 values approximately 0 3 3 1 nM) Its agonism promotes receptor internalization suppressing lymphocyte migration from lymph nodes into the circulation and central nervous system (CNS) Thus fingolimod is studied primarily for autoimmune disorders especially multiple sclerosis due to its effects on lymphocyte trafficking and CNS infiltration
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Medchemexpress LLC Azido-PEG10-amine | 912849-73-1 | 97.0% | C22H46N4O10 | 50 MG
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Azido-PEG10-amine is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is also a click chemistry reagent containing an Azide group, which can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains an Azide group
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions
- Can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
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Ambeed Methyl pyrimidine2carboxylate
Methyl pyrimidine-2-carboxylate, 34253-03-7, 97%
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Ambeed R 4Benzyl2oxazolidinone
(R)-4-Benzyl-2-oxazolidinone, 102029-44-7, 98%
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Ambeed Dicyclohexyl 2 6 diisopropoxy
Dicyclohexyl(2',6'-diisopropoxy-[1,1'-biphenyl]-2-yl)phosphine, 787618-22-8, 97%
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Medchemexpress LLC Z-LYS-SBZL monohydrochloride | 69861-89-8 | 99.7% | C21H27ClN2O3S | 100 MG
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Z-LYS-SBZL monohydrochloride is a lysine derivative. Amino acids and their derivatives are commercially used as ergogenic supplements, recognized for their benefits as dietary substances.
- Influences the secretion of anabolic hormones.
- Supplies fuel during exercise.
- Improves mental performance during stress-related tasks.
- Prevents exercise-induced muscle damage.
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eMolecules 34785-11-0 | Ambeed | 4-Hydroxyquinoline-3-carboxylic acid | 1g | 552554610 | A125405 | MFCD00598887 | 189.17 | C10H7NO3
Ambeed | Potassium (4-butoxyphenyl)trifluoroborate | 250mg | 586458706 | A994142 | 850623-61-9 | MFCD04115755 | 256.120 | C10H13BF3KO
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TARGETMOL CHEMICALS INC MECAMYLAMINE HYDROCHLORI 25MG
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Also available in 5 mg 10 mg 50 mg 100 mg 200 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Mecamylamine hydrochloride (Mevasin) is a nicotinic antagonist used as a ganglionic blocker in hypertension. purity: 99%
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TARGETMOL CHEMICALS INC SAFINAMIDE MESYLATE 25MG
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Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Safinamide mesylate (EMD 1195686 mesylate) a mesylate salt of Safinamide can reversibly and specifically inhibit MAO-B (IC50 98 nM) has 5918-fold selectivity against MAO-A. purity: 98%
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Medchemexpress LLC Argatroban monohydrate | 141396-28-3 | MFCD23102419 | 99.6% | 1 ML
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Argatroban monohydrate is a direct, selective thrombin inhibitor. It may also have a complementary effect for preventing thrombus formation without aggravating bleeding tendency due to its monotarget specificity to thrombin.
- Administration (0.5 to 2 micrograms/kg/min) is a safe anticoagulant for left heart bypass in repairs of traumatic aortic rupture associated with multiple organ injuries.
- Appears to enhance reperfusion with TPA in patients with AMI, particularly in those with delayed presentation, and was associated with lower incidences of major bleeding and adverse clinical outcomes compared to heparin.
- Suitable for creating animal models for thrombolysis.
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