Quinolines and derivatives
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Filtered Search Results
TARGETMOL CHEMICALS INC Tacedinaline 200MG
Also available in 1 mL, 10 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Tacedinaline (CI994) is a selective class I HDAC inhibitor with potential antineoplastic activity. Purity 98.37%
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TARGETMOL CHEMICALS INC SRS16-86 10MG
Also available in 1 mL, 1 mg, 2 mg, 5 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. SRS16-86 is a novel third-generation ferrostatin, is an inhibitor offerroptosis. Purity 99.85%
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Apexbio Technology LLC Olmesartan medoxomil 144689-63-4 200mg
Olmesartan medoxomil (CAS 144689-63-4) is the medoxomil ester prodrug of olmesartan which functions as an orally bioavailable antagonist of the angiotensin II type 1 (AT1) receptor Following gastrointestinal absorption it is rapidly converted to its active metabolite olmesartan resulting in potent AT1 receptor inhibition (IC50 8 nmol/L for olmesartan 33 nmol/L for olmesartan medoxomil) The esterification with medoxomil enhances aqueous solubility Olmesartan medoxomil is widely used in hypertension research enabling evaluation of AT1 receptor blockade on vascular tone blood pressure regulation and renal sodium handling in preclinical and clinical models
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TARGETMOL CHEMICALS INC Amikacin 200MG
Also available in 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Amikacin (Amikacina) is a broad-spectrum antibiotic derived from kanamycin. Purity 99.34%
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TARGETMOL CHEMICALS INC Insulin human 200MG
Also available in 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Insulin (human) is a peptide hormone that promotes glycogen synthesis and regulates glucose levels in the blood. Insulin (human) has hypoglycemic activity and is used clinically to treat hyperglycemia in diabetic patients. Purity 99.99%
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Apexbio Technology LLC Phenanthrene 85-01-8 200mg
Phenanthrene is a polycyclic aromatic hydrocarbon (PAH) that exerts its biological activity primarily through the induction of cellular inflammatory responses enhancement of reactive oxygen species (ROS) generation and activation of apoptotic signaling pathways Based on these pharmacological properties phenanthrene is utilized in research to study PAH-induced cellular toxicity oxidative stress mechanisms and programmed cell death pathways Additionally it serves as a representative analyte in environmental toxicology investigations to detect quantify and evaluate PAH contamination in water and soil supporting the development of toxicological evaluation models and detection methods
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Ambeed 1Naphthoic acid
1-Naphthoic acid, 86-55-5, 98%
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TARGETMOL CHEMICALS INC Azosemide 200MG
Also available in 1 mL, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Azosemide is a potent NKCC1 inhibitor (IC50s 0.246 µM and 0.197 µM for hNKCC1A and NKCC1B). Purity 98.93%
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Ambeed Bis 2ethylhexyl terephthalate
Bis(2-ethylhexyl) terephthalate, 6422-86-2, 98%
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TARGETMOL CHEMICALS INC Matrine 200MG
Also available in 1 mL, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist. Purity 97.16%
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Ambeed 2Bromonaphthalene
2-Bromonaphthalene, 580-13-2, 98%
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Ambeed 1Naphthoic acid
1-Naphthoic acid, 86-55-5, 98%
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Medchemexpress LLC N-(1-phenylethyl)-2-pyrrolidin-1-ylquinazolin-4-amine | 662163-81-7 | MFCD04077630 | 99.9% | 318.42 g·mol^-1 | C20H22N4 | 200 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Importazole is a small-molecule inhibitor of the nuclear transport receptor importin-β used in laboratory research to selectively block importin-β-mediated nuclear import. It is supplied as a white to off-white solid with documented solubility and storage recommendations for reliable use in cell biology studies. For research use only.
- Selective inhibitor of importin-β.
- High purity, typically about 99.9%.
- White to off-white solid form.
- Soluble in DMSO; in vitro and in vivo formulation protocols available.
- Stable under recommended storage conditions for powder and solutions.
- Intended for research use only; not for therapeutic use.
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Apexbio Technology LLC CUDC-101 1012054-59-9 200mg
CUDC-101 (CAS 1012054-59-9) is a multitargeted small molecule inhibitor that concurrently targets epidermal growth factor receptor (EGFR) HER2 and class I and II histone deacetylases (HDACs) By inhibiting EGFR and HER2 kinases directly and simultaneously blocking HDAC activity CUDC-101 downregulates multiple oncogenic signaling pathways including those mediated by Akt HER3 and MET Preclinical assessments demonstrate that CUDC-101 inhibits growth of diverse tumor cell lines and xenograft models notably including those resistant to EGFR-targeted agents such as lapatinib and erlotinib These characteristics render CUDC-101 valuable for oncology research and drug resistance studies
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Apexbio Technology LLC ML385(Synonyms: ML-385, NRF2 inhibitor ML385, ML385 NRF2 inhibitor, ML385 inhibitor, NRF2-IN-1, NRF2-IN1), 200mg, CAS: 846557-71-9.
ML385 (CAS 846557-71-9) is a selective inhibitor of the transcription factor nuclear factor erythroid 2-related factor 2 (NRF2) displaying an IC50 of 1 9 M NRF2 regulates cellular antioxidant responses detoxification pathways and multidrug transporters and its activation is frequently implicated in therapeutic resistance of non-small cell lung cancer (NSCLC) In A549 cells ML385 treatment reduces expression of NRF2-dependent genes dose- and time-dependently Additionally in NSCLC mouse models ML385 treatment diminished tumor growth and metastasis especially when combined with carboplatin underscoring its utility in cancer research and potential therapeutic exploration
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