Tetrapyrroles and derivatives
Abcam TPEN, Metal ion chelator, 100MG
MW 424.5 Da, Purity >99%. Metal ion chelator. Decreases intracellular zinc levels. Induces apoptosis. Causes defects in oocyte maturation. Modulates hippocampal neurogenesis following seizure. Cell permeable. Active in vivo and in vitro.
The product is subject to the following: Abcam Restricted Use Statement
Abcam SB 216763, GSK3 inhibitor, 1MG
MW 371.2 Da, Purity >98%. Potent and selective GSK3 inhibitor (Ki= 9 nM for GSK-3α). Has little activity against 24 other protein kinases (IC₅₀ > 10 μM). Stimulates glycogen synthesis, gene transcription and is cardio- and neuroprotective.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Geldanamycin-FITC, fluorescent labelled HSP90 inhibitor, 1MG
MW 1034.2 g/mol, Purity >98%. Potent fluorescent labelled-HSP90 inhibitor for in vitro and in vivo use. Geldanamycin from Streptomyces hygroscopicus.
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC Phthalocyanine | 574-93-6 | 98.0% | 5 G
Phthalocyanine is a macrocyclic organic compound used as a photosensitizer in photodynamic research and sensor development. It exhibits light-activated antimicrobial activity and can be conjugated for targeted therapeutic and diagnostic applications.
- Photosensitizer with activity against bacterial biofilms.
- Applicable to photodynamic therapy and antimicrobial studies.
- Compatible with conjugation chemistry for targeted delivery or detection.
- Solid, dark purple to black powder, organosoluble.
- Available in small laboratory quantities for research use.
Abcam GBR 12909 dihydrochloride, Dopamine transport inhibitor, 50MG
MW 523.5 Da, Purity >98%. Potent, selective dopamine reuptake inhibitor (IC₅₀ = 2.32 μM in rat hippocampal slices; IC₅₀ = 6-35 μM in whole cell patch clamp recordings).
The product is subject to the following: Abcam Restricted Use Statement
Abcam GR 127935 hydrochloride, 5-HT1B/1D receptor antagonist, 10MG
MW 534.06 g/mol, Purity >97%. Potent and selective 5-HT₁B/₁D receptor antagonist (pKi = 8.5 for both 5-HT₁D in rat and 5-HT₁D in guinea pig). 100-fold selectivity over 5-HT₁A, 5-HT₁E, and 5-HT₂C. Displays centrally mediated effects upon systemic administration.
The product is subject to the following: Abcam Restricted Use Statement
Abcam GS 39783, GABAB positive allosteric modulator, 10MG
MW 337.4 Da, Purity >99%. Novel, GABAB positive allosteric modulator (EC50 = 3 μM for [35S]GTPγS binding). Shows anxiolytic and antiaddictive effects *in vivo.* Blood-brain barrier permeable*.* Orally active.
The product is subject to the following: Abcam Restricted Use Statement
Abcam SB 203580, p38 MAPK inhibitor, 1MG
MW 377.4 Da, Purity >99%. SB 203580, p38 MAPK inhibitor. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Zaprinast, cGMP phosphodiesterase inhibitor, 10MG
MW 271.28 g/mol, Purity >98%. Specific cGMP phosphodiesterase inhibitor, selective for PDE6, 5, 11 and 9 (IC₅₀ values are 0.15 (PDE6), 0.76 (PDE5), 12 (PDE11) and 29 μM (PDE9)). Reputed GPR35 agonist (EC₅₀ values are 16 and 840 nM at rat and human GPR35 receptors, respectively). Important mediator for a variety of cellular processes including vasodilation.
The product is subject to the following: Abcam Restricted Use Statement
Abcam PNU 120596, Positive allosteric modulator for alpha7 nicotinic acetylcholine receptors, 10MG
MW 311.72 Da, Purity >99%. Competitive, type II positive allosteric modulator for α7nAChR (EC₅₀ = 216 nM). Increases potency of nicotinic agonists. No effect on α4β2, α3β4 and α9α10 nAChRs. Active in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam L-threo-PDMP, 10MG
MW 427.03 g/mol, Purity >98%. Enantiomer of D-threo-PDMP (Asc 4052). Activates glycosyltransferases for ganglioside biosynthesis. Antineurodegenerative properties. Active in vivo and in vitro.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Edaravone (MCI-186), antio x idant, 250MG
MW 174.2 Da, Purity >99%. Free radical scavenger and potent antioxidant. Inhibits production of reactive oxygen species, apoptosis and the lipoxygenase system.
The product is subject to the following: Abcam Restricted Use Statement
Abcam (R,S)-CPP, NMDA antagonist, 50MG
MW 252.2 Da. Potent, competitive NMDA antagonist. See separate isomer (ab120159). Also available in simple stock solutions (ab146720) - add 1 ml of water to get an exact, ready-to-use concentration.
The product is subject to the following: Abcam Restricted Use Statement
Abcam (±)-Miconazole nitrate, Imidazole antifungal agent, 1G
MW 479.1 Da, Purity >99%. Imidazole antifungal agent. Inhibits fungal membrane ergosterol biosynthesis. Increases reactive oxygen species production.
The product is subject to the following: Abcam Restricted Use Statement
Abcam GBR 12909 dihydrochloride, Dopamine transport inhibitor, 10MG
MW 523.5 Da, Purity >98%. Potent, selective dopamine reuptake inhibitor (IC₅₀ = 2.32 μM in rat hippocampal slices; IC₅₀ = 6-35 μM in whole cell patch clamp recordings).
The product is subject to the following: Abcam Restricted Use Statement