Tetrapyrroles and derivatives
Medchemexpress LLC Chlorin e6 trimethyl ester | 35038-32-5 | 99.8% | 638.75 | 25 MG
Chlorin e6 trimethyl ester is a methyl pheophorbide-a derivative functioning as a photosensitizer for photodynamic therapy (PDT). This solid, brown to black compound exhibits photo cytotoxic activity against human HepG2 cells and is intended for research use only.
- Used as a photosensitizer
- Applicable in photodynamic therapy (PDT)
- Exhibits photo cytotoxic activity
- Solid appearance with brown to black color
- Soluble in DMSO
Strem, An Ascensus Company CAS# 14609-54-2. 1g. meso-Tetra(4-carboxyphenyl)porphine, 98%. MFCD00064860
CAS# 14609-54-2. 1g. meso-Tetra(4-carboxyphenyl)porphine, 98%. MFCD00064860. Molecular Weight: 790.79. Molecular Formula: C48H30N4O8. Color/form: purple pwdr. Strem# 07-1970. http://www.strem.com/catalog/v/07-1970/
Medchemexpress LLC Zinc(II)-protoporphyrin IX | 15442-64-5 | MFCD00011612 | 98.9% | 626.02 g/mol | C34H32N4O4Zn | 100 MG
Zinc(II)-protoporphyrin IX is a porphyrin derivative used as a heme oxygenase-1 (HO-1) inhibitor in biochemical and pharmacological research. It is applied in studies of oxidative stress, heme metabolism, and related signaling pathways, provided as a stable solid with recommended sealed storage at -20°C for long-term stability.
- Used as an HO-1 inhibitor for mechanistic and pathway studies.
- Well-characterized chemical identity with CAS 15442-64-5.
- High purity suitable for in vitro biochemical assays and preclinical work.
- Soluble in DMSO; manufacturer provides solubility and vehicle preparation guidance.
- Stable when stored sealed at -20°C; solvent storage recommendations available.
Medchemexpress LLC Pyraclonil | 158353-15-2 | 97.0% | 314.77 | 50 MG
Pyraclonil is a chemical compound that acts as a protoporphyrinogen oxidase (PPO) inhibitor. It functions as a herbicide and demonstrates high effectiveness in controlling both susceptible and multiple-herbicide-resistant populations of *E. indica*. Additionally, Pyraclonil is noted for its role as a click chemistry reagent, containing an Alkyne group which allows it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules possessing Azide groups.
- Mechanism of action: PPO inhibitor.
- Application: herbicide, effective against susceptible and multiple-herbicide-resistant *E. indica*.
- Chemical reactivity: click chemistry reagent with an alkyne group, capable of CuAAc reactions with azide-containing molecules.
- In vitro efficacy: shows good control in vitro, leading to 94.5-94.9% and 89.5-90.4% fresh-weight reductions in susceptible and resistant populations, respectively.
TARGETMOL CHEMICALS INC Tin-protoporphyrin IX dichlori
Also available in 1 mg, 10 mg, 25 mg, 50 mg and bulk. Please contact Fisher for quotes. Tin-protoporphyrin IX dichloride (SnPPIX dichloride) is an HO-1) inhibitor with antiviral activity that inhibits dengue and yellow fever viruses. Purity 98%
Selleck Chemical LLC Protoporphyrin IX (PPIX) S5145-1g
Protoporphyrin IX (PPIX) is a heterocyclic organic compound which consists of four pyrrole rings and is the final intermediate in the heme biosynthetic pathway
Medchemexpress LLC Zinc protoporphyrin | 15442-64-5 | MFCD00011612 | 626.02 | C34H32N4O4Zn | 50 MG
Zinc protoporphyrin (Zn(II)-protoporphyrin IX) is a metalloporphyrin research reagent used as a competitive inhibitor of heme oxygenase-1 (HO-1) and as a biomarker in studies of iron deficiency. It is applied in biochemical and cellular assays to probe HO-1 activity and related pathways.
- Competitive heme oxygenase-1 (HO-1) inhibitor.
- Used as a biomarker for iron deficiency in vivo.
- Suitable for biochemical and cellular assays.
- Molecular formula C34H32N4O4Zn; molecular weight 626.02.
- Store at -20°C, sealed and protected from moisture; in solvent store at -80°C for long term.
Selleck Chemical LLC Tin protoporphyrin IX
Tin Protoporphyrin IX dichloride is a potent inhibitor of heme oxygenase-1 (HO-1) reduces ozone-induced pulmonary inflammation and BAL cell necrosis highlighting its protective role It also sensitizes pancreatic ductal adenocarcinoma (PDAC) tumors to chemotherapy in a mouse model suggesting its potential for PDAC treatment
Enzo Life Sciences Protoporphyrin IX (free acid) (1g). CAS: 553-12-8
Protoporphyrin IX free acid, as distinct from its zinc salt (which inhibits heme oxygenase), activates soluble guanylyl cyclase (sGC) by binding directly to the enzyme. A useful reagent in cases where the use of nitric oxide (NO) or nitric oxide donors is undesirable. Alternative name: 8,13-Divinyl-3,7,12,17-tetramethyl-21H,23H-porphine-2,18-dipropionic acid. Purity: ≥95% (HPLC). Appearance: Purple to dark brown solid. Solubility: Dissolve initially in 0.1M base (Tris base or NaOH), then add water miscible organic solvent (EtOH (10mg/ml), MeOH, DMSO (10mg/ml), DMF) until solution is 50/50 base/solvent. When a clear solution is obtained, it can be diluted into an aqueous medium and titrated or buffered to any pH>7. Use immediately. Long Term Storage: -20°C.
Medchemexpress LLC HY-101193 10mg Medchemexpress, Zinc Protoporphyrin CAS:15442-64-5 Purity:>98%
Medchemexpress, HY-101193 10mg Zinc Protoporphyrin CAS:15442-64-5 Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is a competitive heme oxygenase-1 (HO-1) inhibitor, markedly attenuates the protective effects of Phloroglucinol (PG) against H2O2. Zinc Protoporphyrin is a normal metabolite formed in trace amounts during heme biosynthesis and used as a screening marker of iron deficiency in individual pregnant women and children, but also to assess population iron status in combination with haemoglobin concentration. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Coproporphyrin I dihydrochloride | 69477-27-6 | MFCD00013469 | 98.0% | 727.63 | C36H40Cl2N4O8 | 10 MG
Coproporphyrin I dihydrochloride is a biochemical reagent and endogenous porphyrin metabolite supplied as a solid for life-science research applications, including studies of liver disease and porphyria. It is commonly used as a reference material or reagent in biochemical assays.
- High purity (98.0%) solid, purple to purplish red.
- Molecular weight 727.63 g·mol⁻¹ and formula C36H40Cl2N4O8.
- Soluble in DMSO (125 mg/mL); ultrasonic assistance recommended.
- Storage: in solvent, -80°C (2 years) or -20°C (1 year); store solid dry and cool.
- Typical applications: biochemical assays and metabolite research.
Medchemexpress LLC Coproporphyrin III dihydrochloride | 68938-73-8 | MFCD00058927 | 99.6% | 727.63 g/mol | C36H40Cl2N4O8 | 10 MG
Coproporphyrin III dihydrochloride is a porphyrin derivative supplied as a high-purity solid and as ready-to-use DMSO solutions for research use. It is commonly used in biochemical and microbiological studies to investigate endogenous porphyrins, bacterial metabolites, and related assays.
- High purity suitable for analytical and biological assays.
- Available as solid and ready-to-use DMSO solutions.
- Suitable for studies of endogenous porphyrins and bacterial metabolites.
- Well-characterized with reported CAS number, molecular formula, and molecular weight.
- Supplied in small quantities appropriate for laboratory-scale experiments.
Enzo Life Sciences Zinc(II) Protoporphyrin IX (25mg). CAS: 15442-64-5
Potent and selective inhibitor of heme oxygenase (Ki=3nM), the enzyme that generates carbon monoxide (CO). Inhibits soluble guanylyl cyclase. Produces a time- and concentration-dependent inactivation of all three isoforms of nitric oxide synthase (IC50=0.8µM, 4.0µM, and 5.0µM for nNOS (NOS I), iNOS (NOS II) and eNOS (NOS III), respectively). Does not cross the blood-brain barrier. An useful tool to elucidate the role of CO in signal transduction and as a neurotransmitter. Purity: ≥95% (TLC). Solubility: Soluble in pyridine, dimethyl formamide or DMSO. Colloidal in aqueous base; slightly soluble in aqueous base/organic solvent mixtures. Long Term Storage: -20°C.
Medchemexpress LLC Protoporphyrin IX | 553-12-8 | MFCD00005740 | 98.0% | 250 MG
Protoporphyrin IX | 553-12-8 | MFCD00005740 | 98.0% | 250 MG
Medchemexpress LLC Hematoporphyrin monomethyl ether | 148471-91-4 | MFCD32215011 | 95.0% | 1225.43 | C70H80N8O12 | 5 MG
Hematoporphyrin monomethyl ether is a porphyrin-based photosensitizer used in photodynamic therapy and related biochemical research. It is supplied as a purple to purplish-red solid with high purity and characterized solubility in DMSO; handle and store protected from light.
- Solid, purple to purplish red appearance
- Purity approximately 95.0%
- Soluble in DMSO (≈62.5 mg/mL); in vivo formulations documented
- Storage: solid at 4°C; solutions at -80°C (6 months) or -20°C (1 month); protect from light
- Used as a photosensitizer for photodynamic therapy research and tissue visualization