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2-Thiouridine (uridine, 2-thio-) is a modified nucleoside used in nucleic acid research. It stabilizes U:A base pairs and destabilizes U:G wobble base pairs, improving the efficiency and accuracy of nonenzymatic replication of mixed-sequence A/U-containing RNA templates. It has reported in vitro antiviral activity against several positive-sense RNA viruses. Supplied as a high-purity solid for laboratory research use only.
High purity, typically 99.7%.
Chemical formula C9H12N2O5S, molecular weight 260.27 g·mol⁻¹.
Supplied as a 100 MG solid suitable for in vitro studies.
Used to study base-pairing stability, RNA replication, and antiviral assays.
Not for human or clinical use; for research use only.
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