Carboximidamides
Sigma Aldrich Biuret
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich Selenourea
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Medchemexpress LLC 5'-Phosphoguanylyl-(3',5')-guanosine | 33008-99-0 | MFCD00064360 | 95.8% | 708.43 g/mol | C20H26N10O15P2 | 5 MG
5'-Phosphoguanylyl-(3',5')-guanosine (pGpG) is a nucleotide intermediate produced during enzymatic degradation of cyclic di-guanylate (c-di-GMP). It is supplied as a purified research reagent for biochemical and microbiology studies involving nucleotide signaling and enzymology.
- Purity 95.8% suitable for analytical and biochemical assays.
- Molecular weight 708.43 g/mol.
- Chemical formula C20H26N10O15P2.
- Available in milligram scales (5 mg, 10 mg, 25 mg, 50 mg, and larger sizes).
- Intended for biochemical assays and studies of nucleotide signaling and c-di-GMP metabolism.
- Provided with characterization data to support research use.
Medchemexpress LLC Parishin C | 174972-80-6 | 5 MG
Parishin C is a parishin derivative isolated from *Gastrodia elata* that may possess antioxidant properties. It is the analytical standard of Parishin C, intended for research and analytical applications.
- Derived from *Gastrodia elata*
- May possess antioxidant properties
- Analytical standard for research and analytical applications
- Purity: 99.24%
- Molecular weight: 728.65
- Molecular formula: C₃₂H₄₀O₁₉
- Appearance: Solid
- Color: White to off-white
- Soluble in DMSO and H₂O
- Store solid at 4°C, protected from light
- Store in solvent at -80°C for 6 months or -20°C for 1 month, protected from light
Apexbio Technology LLC MRTX-1133(Synonyms: MRTX1133, MRTX 1133, Mirati-1133, KRAS G12D inhibitor MRTX1133), 5mg, CAS: 2621928-55-8.
MRTX-1133 (CAS 2621928-55-8) is a non-covalent alkyne-based inhibitor specifically targeting the KRAS G12D mutant protein It binds KRAS G12D with sub-picomolar affinity occupying the Switch II pocket and forming multiple intermolecular interactions Through these interactions MRTX-1133 disrupts SOS1-mediated guanine nucleotide exchange and prevents the assembly of KRAS-GTP/RAF1 signaling complexes thereby inhibiting downstream KRAS-driven signaling pathways MRTX-1133 is applied in cancer biology research to investigate tumor signaling and therapeutic strategies involving KRAS G12D mutations
Apexbio Technology LLC MYK-461 1642288-47-8 10mM (in 1mL DMSO)
MYK-461 is a small-molecule inhibitor interacting directly with cardiac myosin heavy chain to modulate myocardial contraction It specifically reduces myocardial contractility through inhibition of cardiac myosin ATPase enzymatic activity thereby limiting myosin-mediated phosphate release without affecting ADP dissociation rates In rodent cardiomyocytes MYK-461 demonstrates dose-dependent reductions in fractional shortening and sarcomeric force generation without impacting calcium transient dynamics Its inhibitory potency against cardiac myosin ATPase surpasses that observed for skeletal muscle isoforms In preclinical hypertrophic cardiomyopathy mouse models MYK-461 administration attenuates cardiac contractile function facilitating investigations into myocardial contractility regulation and potential therapeutic strategies against hypertrophic cardiomyopathy
Medchemexpress LLC Clonidine hydrochloride | 4205-91-8 | 99.9% | 1 ML
Clonidine hydrochloride is an agonist of α2-adrenoceptor and a potent antihypertensive agent, primarily intended for research use. This specific product is a 10 mM solution in DMSO.
- Agonist of α2-adrenoceptor
- Potent antihypertensive agent
- For research use only
- High purity: 99.9%
- Induces CGRP mRNA expression in endothelial cells
- Increases NO level in endothelial cells
- Suppresses dopamine efflux in the prefrontal cortex
- Solution stable at -20°C for 1 month or -80°C for 6 months
Chem-Impex International, Inc. Tetramethylfluoroformamidiniun hexafluorophosphate | 164298-23-1 | MFCD02684443 | 25G
Tetramethylfluoroformamidiniun hexafluorophosphate, 164298-23-1, MFCD02684443, 25G
Medchemexpress LLC Creatine (standard) | 57-00-1 | 99.98% | 131.13 | 250 MG
Creatine (Standard) is the analytical standard of Creatine, intended for research and analytical applications. Creatine is an endogenous amino acid derivative that plays an important role in cellular energy, particularly in muscle and brain.
- Analytical standard for Creatine.
- Intended for research and analytical applications.
- Commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Endogenous metabolite.
- Formula: C4H9N3O2.
- Appearance: Solid, white to off-white.
- Structure classification: Amino acids.
- Initial source: Endogenous metabolite, Disease markers (Cancer, Nervous System Disorder), Human Gut Microbiota Metabolites.
Medchemexpress LLC Ccr4-351 | 2174938-70-4 | MFCD32701932 | 99.0% | 500.42 g/mol | C24H27Cl2N7O | 5 MG
CCR4-351 is a small-molecule, orally active CCR4 antagonist used for preclinical research. It shows potent and selective activity in cellular assays and has demonstrated antitumor efficacy in animal models. For research use only; consult the supplier datasheet and safety documents for handling, storage, and dosing guidance.
- Orally active and selective CCR4 antagonist.
- Demonstrated antitumor activity in vivo.
- Potent activity in cellular assays (low-nanomolar IC50 reported).
- High chemical purity suitable for research applications.
- Provided as a solid form for in vitro and in vivo studies.
- Refer to the product datasheet and safety documents for handling and dosing.
Medchemexpress LLC Melitracen hydrochloride | 10563-70-9 | MFCD00242905 | 99.8% | 327.89 g/mol | C21H26ClN | 50 MG
Melitracen hydrochloride is the hydrochloride salt of melitracen, supplied as a high-purity research standard for analytical, pharmacological, and formulation studies. It is a white to off-white solid (CAS 10563-70-9) with defined solubility and storage recommendations to support reproducible results.
- High purity suitable for analytical and pharmacological research.
- White to off-white solid with consistent physical properties.
- Soluble in water and DMSO; may require sonication.
- Store solid at 4°C, sealed and protected from moisture; solutions at -80°C (long term) or -20°C (short term).
- Supplied in small pack sizes convenient for assay and preclinical work.
![Medchemexpress LLC 1-(4-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)butyl)-3-methyl-1H-benzo[d]imidazol-2(3H)-one | 1121931-70-1 | 99.9% | C23H29N3O3 | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000258307.png-250.jpg)
Medchemexpress LLC 1-(4-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)butyl)-3-methyl-1H-benzo[d]imidazol-2(3H)-one | 1121931-70-1 | 99.9% | C23H29N3O3 | 10MG
CM398 is a selective, orally active sigma-2 receptor ligand used for receptor pharmacology and in vivo pain models. It has been characterized for receptor affinity and shows anti-inflammatory analgesic effects in preclinical studies.
- High potency and selectivity for sigma-2 receptor (Ki = 0.43 nM).
- Demonstrated efficacy in the formalin inflammatory pain model.
- High purity suitable for research applications (99.85%).
- Soluble in DMSO (100 mg/mL); supports multiple in vivo formulation options.
- Stable under recommended storage conditions for long-term use.
![Medchemexpress LLC Pyrrolo[3,4-b]pyrrole-5(1H)-carboxamide, N-[4-[(3-ethynylphenyl)amino]-7-methoxy-6-quinazolinyl] | 1353644-70-8 | 99.7% | 442.51 g/mol | C25H26N6O2 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000243817.png-250.jpg)
Medchemexpress LLC Pyrrolo[3,4-b]pyrrole-5(1H)-carboxamide, N-[4-[(3-ethynylphenyl)amino]-7-methoxy-6-quinazolinyl] | 1353644-70-8 | 99.7% | 442.51 g/mol | C25H26N6O2 | 50 MG
Theliatinib is a potent, ATP-competitive, orally active, and highly selective epidermal growth factor receptor (EGFR) inhibitor provided for research use in preclinical biochemical and cell-based studies.
- Potent ATP-competitive EGFR inhibitor with low-nanomolar activity.
- High chemical purity (99.72%).
- Molecular weight 442.51 g/mol; formula C25H26N6O2.
- Soluble in DMSO (~1 mg/mL) with recommended warming and pH adjustment.
- Stable when stored under recommended powder and solution conditions.
- Suitable for studies of wild-type and mutant EGFR signaling.