Carboximidamides
Sigma Aldrich Nalpha,Nalpha-Bis(Carboxymethyl)-L-Lysine Hydrate
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich 4-(Methoxymethoxy)benzoic acid
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich 5-Methyl-1H-pyrazole
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
eMolecules 1399191-70-8 | Ambeed | 55-(14-Phenylene)dipicolinaldehyde | 100mg | 603089926 | A1226399 | 288.306 | C18H12N2O2
Medchem Express | SB 242084 | 5mg | 446262835 | HY-13409 | 181632-25-7 | MFCD05662310 | 394.860 | C21H19ClN4O2
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Medchemexpress LLC 1-tert-butyl N-(5R)-substituted triazole-4-carboxamide (BIIB091) | 2247614-80-6 | 99.9% | 542.64 g/mol | C28H34N10O2 | 5 MG
BIIB091 is a potent, selective, orally active, reversible Bruton tyrosine kinase (BTK) inhibitor supplied for laboratory research. It shows sub-nanomolar enzymatic potency and is provided as solid material or as a DMSO solution for in vitro and preclinical studies; refer to the manufacturer datasheet for safety, handling, and the certificate of analysis.
- Sub-nanomolar BTK potency (IC50 <0.5 nM).
- Reversible and highly selective BTK inhibition.
- Chemical formula C28H34N10O2; molecular weight 542.64 g/mol.
- Available as solid quantities and as a 10 mM solution in DMSO.
- High purity (>99.8% by HPLC) suitable for research applications.
eMolecules 872044-70-7 | Medchem Express | AN0128 | 5mg | 705860157 | HY-10979 | MFCD18251581 | 400.06 | C20H16BCl2NO3
Medchem Express | AN0128 | 5mg | 705860157 | HY-10979 | 872044-70-7 | MFCD18251581 | 400.060 | C20H16BCl2NO3
Medchemexpress LLC Boldine | 476-70-0 | 5 MG
Boldine is an apomorphine isoquinoline alkaloid extracted from the root of the pheasant pepper (Litsea cubeba). It is an orally effective antioxidant, anti-inflammatory, and antitumor agent that can inhibit osteoclast formation. Boldine induces apoptosis of human bladder cancer cells by regulating ERK, AKT, and GSK-3β, and it ameliorates bone destruction by down-regulating the OPG/RANKL/RANK signaling pathway. It can be used in rheumatoid arthritis research.
- Purity: 99.0%
- Appearance: Solid
- Color: Off-white to light yellow
- Molecular weight: 327.37
- Formula: C19H21NO4
- Structure classification: Alkaloids, isoquinoline alkaloids, phenols, polyphenols
- Initial source: Plants, Lauraceae, Litsea cubeba (Lour.) Pers.
eMolecules 50-01-1 | Guanidine hydrochloride | Chem-Impex | MFCD00013026 | 95.530 | CH6ClN3 | 99.000 | Cl.NC(N)=N | 1kg | 342450112
Guanidine hydrochloride | Chem-Impex | 50-01-1 | MFCD00013026 | 95.530 | CH6ClN3 | 99.000 | Cl.NC(N)=N | 1kg | 342450112
eMolecules 2361162-70-9 | Medchem Express | TCL053 | 5mg | 784544044 | HY-147332 | 874.342 | C53H95NO8
Ambeed | 4-Iodoisoquinoline | 250mg | 490506938 | A135119 | 55270-33-2 | MFCD00234496 | 255.058 | C9H6IN
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Medchemexpress LLC Pentagamavunon-1 (PGV-1) | 27060-70-4 | 98.95% | 348.43 | 100 MG
Pentagamavunon-1 (PGV-1) is a Curcumin analog with oral activity. It targets multiple molecular mechanisms to induce apoptosis, including the inhibition of angiogenic factors cyclooxygenase-2 (COX-2) and vascular endothelial growth factor (VEGF). PGV-1 also inhibits NF-κB activation.
- Enhances the cytotoxic effect of 5-FU on WiDr cells
- Induces G2/M arrest
- Exhibits significant anti-tumor activity in a PDX model
- Shows minimal adverse effects on normal cells
- Soluble in DMSO for in vitro studies
- Soluble in 10% DMSO and 90% (20% SBE-β-CD in saline) for in vivo studies
- Soluble in 10% DMSO and 90% corn oil for in vivo studies
Medchemexpress LLC Creatine-13C | 687996-99-2 | 98.5% | 132.13 | 25 MG
Creatine-13C is a 13C labeled Creatine, which is an endogenous amino acid derivative. It plays a significant role in cellular energy, particularly in muscle and brain. It is intended for research use only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis through methods like NMR, GC-MS, or LC-MS.
- Stable heavy isotope of carbon (13C) incorporated into the molecule.
Medchemexpress LLC H3B-6545 | 2052130-80-8 | 99.4% | 567.58 | 50 MG
H3B-6545 is an oral, selective estrogen receptor covalent antagonist (SERCA) for the research of metastatic ER-positive, HER2-negative breast cancer. It is for research use only and not sold to patients.
- Oral, selective estrogen receptor covalent antagonist (SERCA).
- Designed for research into metastatic ER-positive, HER2-negative breast cancer.
- Potently antagonizes wild-type and mutant ERα in biochemical and cell-based assays.
- Inactivates wild-type and mutant ERα by targeting C530.
- Inhibits ERαWT activity and suppresses proliferation of ERαWT-positive breast cancer cell lines.
- Demonstrates superior efficacy to fulvestrant and tamoxifen in xenograft and patient-derived xenograft models.
- Well tolerated across a broad dose range in rats and monkeys.
Medchemexpress LLC CCR4-351 | 2174938-70-4 | MFCD32701932 | 99.0% | C24H27Cl2N7O | 10MG
CCR4-351 is an orally active, potent, and selective chemokine receptor 4 (CCR4) antagonist for research use. It features a novel piperidinyl-azetidine motif and exhibits low-nanomolar activity in functional assays (reported IC50 ≈ 22 nM in calcium flux and ≈ 50 nM in CTX). The compound has shown antitumor activity in preclinical studies and is supplied at high purity for experimental applications.
- Potent CCR4 antagonist with low-nanomolar activity.
- Selective activity in CCR4 functional assays.
- Demonstrated antitumor activity in preclinical models.
- Suitable for in vitro and in vivo CCR4 pathway research.
- High purity (≈98.95%) for reliable experimental results.