Flavonoids
TARGETMOL CHEMICALS INC NOBILETIN 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Nobiletin (Hexamethoxyflavone) is a natural polymethoxylated flavone isolated from citrus peels with anti-inflammatory and anti-tumor activities. Nobiletin is practically insoluble (in water) and an extremely weak acidic compound (based on its pKa). purity: 98%
Cayman Chemical rac-HesperetIn-d3 1mg
An internal standard for the quantification of hesperetin by GC- or LC-MS
Cayman Chemical ChrysIn 7-GlucuronIde 25mg
A flavonoid glucuronide with diverse biological activities and an active metabolite of chrysin; inhibits α-glucosidase, α-amylase, and neuraminidase (IC50s = 612, 980, and 428 UG/ml, respectively); inhibits OATP1A2, OATP1B1, OATP1B3, OATP2B1, BCRP, and MRP2 (IC50s = 24.1, 4.4, 14.3, 0.3, 19.8, and 11.2 µM, respectively)
Cayman Chemical ChrysIn 7-GlucuronIde 10mg
A flavonoid glucuronide with diverse biological activities and an active metabolite of chrysin; inhibits α-glucosidase, α-amylase, and neuraminidase (IC50s = 612, 980, and 428 UG/ml, respectively); inhibits OATP1A2, OATP1B1, OATP1B3, OATP2B1, BCRP, and MRP2 (IC50s = 24.1, 4.4, 14.3, 0.3, 19.8, and 11.2 µM, respectively)
Medchemexpress LLC 4'-Hydroxyflavone | 4143-63-9 | MFCD00017687 | 97.0% | 238.24 g/mol | C15H10O3 | 10 MG
4'-Hydroxyflavone is a flavone-class small molecule used in research as an aldose reductase inhibitor. It is supplied as a high-purity research reagent for biochemical assays and is commonly used in enzyme inhibition studies, structure-activity relationship (SAR) investigations, and small-molecule screening.
- High purity (97.0%)
- Molecular formula C15H10O3
- Molecular weight 238.24 g/mol
- CAS number 4143-63-9
- Reported aldose reductase IC50 12 μM
- Suitable for enzyme inhibition assays and SAR studies
Medchemexpress LLC (±)-Catechin (rel-Cianidanol; rel-Catechuic acid) | 7295-85-4 | 99.5% | 1 ML
(±)-Catechin (rel-Cianidanol; rel-Catechuic acid) | 7295-85-4 | 99.5% | 1 ML
Medchemexpress LLC Apigenin (standard) | 520-36-5 | 270.24 | 50 MG
Apigenin (Standard) is an analytical standard intended for research and analytical applications. It is a competitive CYP2C9 inhibitor with a Ki of 2 μM and serves as a reference standard for assays.
- Analytical standard for research and analytical applications
- Competitive CYP2C9 inhibitor
- Reference standard for assays
- Used in qualitative, quantitative, and methodological research experiments
- Suitable for HPLC, GC, and MS applications
Medchemexpress LLC Hesperidin methylchalcone | 1 g | | HY-126382-1g | 24292-52-2 | MW: 624.59
Hesperidin methylchalcone (Hesperidin methyl chalcone) is an orally active flavonoid that has analgesic, anti-inflammatory and antioxidant properties. Hesperidin methylchalcone exhibits vasoprotective activity. Hesperidin methylchalcone inhibits oxidative stress, cytokine production and NF-κB activation. Hesperidin methylchalcone can be used for the research of gout disease.
Medchemexpress LLC Luteolin 7-O-glucuronide | 29741-10-4 | 462.36 | 5 MG
Luteolin 7-O-glucuronide is a compound that inhibits Matrix Metalloproteinases (MMP) activities, with specific IC50 values for MMP-1, MMP-3, MMP-8, MMP-9, and MMP-13. It also demonstrates biological activity by inhibiting NO production and the mRNA expression of various inflammatory mediators, as well as NF-κB, p38, and JNK activation in LPS-stimulated RAW 264.7 macrophages. In vivo studies suggest it can improve depression-like and stress coping behaviors in sleep-deprived mice models.
- Inhibits matrix metalloproteinases (MMPs) activities
- Inhibits NO production in LPS-stimulated RAW 264.7 macrophages
- Reduces mRNA expression of inflammatory mediators
- Suppresses NF-κB, p38, and JNK activation
- Improves depression-like and stress coping behaviors in sleep deprivation models
- Decreases immobility time and plasma corticosterone levels
- Enhances BDNF mRNA expression in the hippocampus
Medchemexpress LLC 4'-Hydroxyflavanone | 6515-37-3 | 10 MG
This chemical is a synthetic analog of flavanone that functions as an inhibitor of SREBP maturation and lipid synthesis. It holds potential for investigations into hepatic steatosis and dyslipidemia.
- It is an inhibitor of SREBP maturation.
- It inhibits lipid synthesis.
- It is a synthetic analog of flavanone.
- It has potential for research related to hepatic steatosis.
- It has potential for research related to dyslipidemia.
- It is classified as a flavonoid and flavanone.
- It is classified as a phenol and monophenol.
- It is derived from microorganisms, specifically *Aspergillus niger*.
Medchemexpress LLC Luteolin-7-rutinoside | 20633-84-5 | 5 MG
Luteolin-7-rutinoside possesses both anti-arthritic and antifungal activities, which can lead to a combination therapy for treating fungal arthritis caused by *C. albicans* infection. It is intended for research use only and not for sale to patients.
- Possesses anti-arthritic activity.
- Possesses antifungal activity.
- Reduces proliferation of T cells in a dose-dependent manner.
- Shifts Th1-Th2 balance away from Th1 towards Th2-type responses.
- Inhibits nitric oxide (NO) production from macrophages.
TARGETMOL CHEMICALS INC SAKURANETIN 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Sakuranetin a flavanone phytoalexin from ultraviolet-irradiated rice leaves it has antifungal antimutagenic anti-inflammatory and antioxidant effectspurity: 99%
Medchemexpress LLC 5,7,3',4'-Tetramethoxyflavone | 855-97-0 | 10 MG
5,7,3',4'-Tetramethoxyflavone is an orally active polymethoxyflavone (PMF) isolated from M. exotica. It possesses various bioactivities, including anti-fungal, anti-malarial, anti-mycobacterial, and anti-inflammatory activities. It also exhibits chondroprotective activity by targeting β-catenin signaling.
- Possesses anti-fungal, anti-malarial, anti-mycobacterial, and anti-inflammatory properties.
- Exhibits chondroprotective activity by targeting β-catenin signaling.
- Protects chondrocytes from ER stress-induced apoptosis.
- Decreases inflammatory cytokines.
- Inhibits chondrocyte hypertrophy.