Flavonoids
Medchemexpress LLC Troxerutin | 7085-55-4 | 98.0% | 742.68 | 10 G
Troxerutin, also known as vitamin P4, is a tri-hydroxyethylated derivative of natural bioflavonoid rutins. It is capable of inhibiting the production of reactive oxygen species (ROS) and depressing ER stress-mediated NOD activation.
- Inhibits ROS production
- Depresses ER stress-mediated NOD activation
- Lowers body weight and improves metabolic parameters
- Restores glucose intolerance and insulin signaling
- Attenuates vascular damages
Selleck Chemical LLC 7-Hydroxyflavone S5380-1g
7-Hydroxyflavone is a potent inhibitor of CYP1A1 with a Ki value of 0 015 M and exhibits 6-fold greater selectivity for CYP1A1 over CYP1A2 It also has excellent antioxidant properties and great potential to be applied as medicines
TARGETMOL CHEMICALS INC 4-Hydroxyflavone 10MG
Also available in 1 mg, 5 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. 4'-Hydroxyflavone is a flavonoid compound isolated from the roots of Scutellaria baicalensis with anti-inflammatory activity. Purity 99.42%
Medchemexpress LLC Chrysin-7-O-glucuronide | 35775-49-6 | 1 ML
Chrysin-7-O-glucuronide is a flavonoid extracted from *Scutellaria baicalensis*, possessing antioxidant activity. It inhibits α-glucosidase and α-amylase, suppresses NF-κB signaling activity, scavenges free radicals, acts as a tight junction protector, and mitigates intestinal mucosal barrier injury. This compound is suitable for research related to type 2 diabetes and severe acute pancreatitis-induced intestinal barrier injury.
- Inhibits alpha-glucosidase and alpha-amylase
- Suppresses NF-κB signaling activity
- Scavenges free radicals
- Acts as a tight junction protector
- Mitigates intestinal mucosal barrier injury
- Restores ZO-1 expression and tight junction structure
- Ameliorates SAP-induced intestinal mucosal barrier injury in rats
Medchemexpress LLC Chrysin (5,7-Dihydroxyflavone) | 480-40-0 | 99.8% | C15H10O4 | 1 ML
Chrysin is a naturally occurring flavonoid found in passion flowers, honey, and propolis. It is an estrogen blocker intended for research use only and acts as a potential therapeutic and preventive agent against the proliferation and invasion of various human cancer cells. It has shown anti-carcinogenic effects by inhibiting ovarian cancer cell proliferation, inducing cell death through increased reactive oxygen species (ROS) production, elevated cytoplasmic Ca2+ levels, and loss of mitochondrial membrane potential (MMP).
- Activates MAPK and PI3K/AKT pathways
- Suppresses tumor growth by regulating canonical Wnt and nuclear factor NF-κB signaling cascades
- Stimulates phosphorylation of AKT and P70S6K proteins
- Activates phospho-ERK1/2, p38, and JNK proteins within the MAPK pathway in ovarian cancer cells
Medchemexpress LLC Chrysin (Standard) | 480-40-0 | 99.96% | C₁₅H₁₀O₄ | 100 MG
Chrysin (Standard), also known as 5,7-Dihydroxyflavone, is a high-purity analytical standard (99.96%) with the chemical formula C₁₅H₁₀O₄ and CAS number 480-40-0. This flavonoid is primarily utilized as a reference standard in various research and analytical applications, including qualitative, quantitative, and methodological experiments using techniques such as HPLC, GC, and MS.
- Used as an analytical standard
- Ideal for qualitative, quantitative, and methodological research experiments
- Suitable for techniques like HPLC, GC, and MS
- Functions as a reference standard for various assays
- A naturally occurring flavonoid and flavone
- Found in plants and as an endogenous metabolite in human gut microbiota
- Known as an estrogen blocker, useful in estrogen receptor and ERR inhibition research
Cayman Chemical HesperIdIn methylchalconC 100g
A C. aurantium extract that contains hesperidin methylchalcone, among other compounds
Medchemexpress LLC 3',4'-dimethoxy-α-naphthoflavone | 14756-24-2 | MFCD00143008 | 98.5% | 332.35 | C21H16O4 | 25 MG
DiMNF (3',4'-Dimethoxy-αNF) is a selective aryl hydrocarbon receptor (AHR) modulator used in laboratory research. It acts as a competitive AHR ligand with a reported IC50 = 21 nM and exhibits apparent antagonistic activity; it is applied in studies of AHR-mediated signaling and inflammatory responses. For research use only.
- Competitive AHR ligand (IC50 = 21 nM).
- Used to study AHR signaling and inflammation.
- High purity (98.46%).
- Molecular formula C21H16O4; molecular weight 332.35.
- Available as solids (including 25 mg) and as 10 mM solutions in DMSO.
- Intended for laboratory research only; not for human use.
Medchemexpress LLC Hesperidin methylchalcone | 24292-52-2 | 98.0% | 624.59 | 5 G
Hesperidin methylchalcone is an orally active flavonoid with analgesic, anti-inflammatory, and antioxidant properties. This compound exhibits vasoprotective activity, and it inhibits oxidative stress, cytokine production, and NF-κB activation. It can be utilized for research related to gout disease.
- Orally active flavonoid
- Analgesic properties
- Anti-inflammatory properties
- Antioxidant properties
- Vasoprotective activity
- Inhibits oxidative stress
- Inhibits cytokine production
- Inhibits NF-κB activation
- Useful for research related to gout disease
Medchemexpress LLC Hesperidin | 520-26-3 | MFCD00006766 | C₂₈H₃₄O₁₅ | 1 G
Hesperidin (Hesperetin 7-rutinoside) is a flavanone glycoside isolated from citrus fruits.
- Decreases inflammatory mediators
- Exerts significant antioxidant effects
- Exhibits antitumor and antiallergic activities
Cayman Chemical rac-HesperetIn-d3 1mg
An internal standard for the quantification of hesperetin by GC- or LC-MS
Medchemexpress LLC 5,7-Dimethoxyflavone | 21392-57-4 | 1 ML
5,7-Dimethoxyflavone is a major component of *Kaempferia parviflora* with diverse biological activities. It exhibits anti-obesity, anti-inflammatory, and antineoplastic effects. This compound acts as an inhibitor of cytochrome P450 (CYP) 3As and is a potent Breast Cancer Resistance Protein (BCRP) inhibitor.
- Exhibits anti-obesity, anti-inflammatory, and antineoplastic effects
- Acts as a potent inhibitor of CYP3A and BCRP
- Inhibits Bcrp1-mediated Sorafenib efflux
- Induces melanogenesis
- Inhibits lipid accumulation and adipocyte differentiation
- Reduces liver CYP3A11 and CYP3A25 protein expression
- Inhibits sarcopenia
- Decreases body weight gain and inhibits fatty liver
