Phenols
Medchemexpress LLC Isocytosine | 108-53-2 | 111.10 | 100 G
Isocytosine is a non-natural nucleobase and an isomer of cytosine. It is utilized in conjunction with Isoguanine for research involving unnatural nucleic acid analogues of the standard base pairs found in DNA, and also serves as a nucleobase component of hachimoji RNA.
- Non-natural nucleobase
- Isomer of cytosine
- Used in research of unnatural nucleic acid analogues
- Component of hachimoji RNA
- Solid appearance
- Off-white to light yellow color
- Store at 4°C, protect from light
- Store in solvent at -80°C for 6 months; -20°C for 1 month, protect from light
Medchemexpress LLC Luseogliflozin hydrate | 1152425-66-5 | 99.2% | 452.56 g/mol | C23H32O7S | 25 MG
Luseogliflozin hydrate is a research-grade sodium-glucose cotransporter 2 (SGLT2) inhibitor provided as the hydrate form. It is a potent and selective compound used in preclinical studies of glucose homeostasis and type 2 diabetes mellitus. The material is supplied as a high-purity solid suitable for in vitro and in vivo research applications.
- Potent SGLT2 inhibition (IC50 ≈ 2.26 nM).
- High purity (99.2%) suitable for research use.
- Hydrate form for consistent physicochemical properties.
- Molecular weight 452.56 g/mol; formula C23H32O7S.
- White to off-white solid, typically supplied in 25 MG quantities.
- Suitable for in vitro and in vivo studies of glucose transport and metabolism.
Medchemexpress LLC XP-524 | 2344825-52-9 | 98.0% | 552.65 | 50 MG
XP-524 is a potent BET and EP300 inhibitor that has shown significant tumoricidal activity in vivo, preventing KRAS-induced neoplastic transformation and prolonging survival in aggressive pancreatic ductal adenocarcinoma (PDAC) models. It also enhances self-peptide presentation and tumor recruitment of cytotoxic T lymphocytes, making it a promising candidate for PDAC research.
- Potent BET and EP300 inhibitor
- Exhibits tumoricidal activity in vivo
- Prevents KRAS-induced neoplastic transformation
- Prolongs survival in pancreatic ductal adenocarcinoma models
- Enhances presentation of self-peptide
- Improves tumor recruitment of cytotoxic T lymphocytes
- Suitable for research into pancreatic ductal adenocarcinoma
Medchemexpress LLC Closantel (sodium) | 61438-64-0 | 99.8% | 685.06 | 1 ML
Closantel sodium is a halogenated salicylanilide with potent anti-parasitic activity. It acts as a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor, inhibiting the O. volvulus L3 to L4 molt of developing parasites. This compound is highly specific for filarial family chitinases compared to those from protozoans and the human chitinase, human chitotriosidase.
- Potent anti-parasitic activity.
- Highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor.
- Inhibits O. volvulus L3 to L4 molt.
- Highly specific for filarial family chitinases.
- For research use only.
Medchemexpress LLC 2-Methoxyhydroquinone | 824-46-4 | 99.6% | 140.14 | 50 G
2-Methoxyhydroquinone is a phenolic compound that reduces TNF-α-induced production of chemokine (C-C motif) ligand 2 (CCL2) with an IC50 value of 64.3 μM. It is also a precursor in the synthesis of the Hsp90 inhibitor Geldanamycin.
- CCL2 Inhibitor
- Precursor in the synthesis of the Hsp90 inhibitor Geldanamycin
- Exhibits antiproliferative activity against human A375, A549, HCT-116, HFF-1, MCF-10A, and SK-MEL-2 cells with an EC50 > 100 μM
Medchemexpress LLC Bruceine E | 21586-90-3 | 1 MG
Bruceine E is a quassinoid derived from the seeds of *Brucea javanica* (L.) Merr, known for its hypoglycemic effects. It has demonstrated blood glucose lowering capabilities in both nondiabetic mice and Streptozotocin (STZ)-induced diabetic rats at low doses.
- Quassinoid derived from *Brucea javanica* seeds
- Exhibits hypoglycemic effects
- Demonstrates blood glucose lowering in nondiabetic and diabetic animal models
- High purity (97.32%)
- White to off-white solid appearance
- Soluble in DMSO and various in vivo protocols
Medchemexpress LLC 3-(4-tert-butylphenyl)-2-methylpropanal | 80-54-6 | MFCD00047655 | 98.0% | 204.31 g/mol | C14H20O | 100 G
Lilial (3-(4-tert-butylphenyl)-2-methylpropanal, CAS 80-54-6) is an aromatic aldehyde used as a floral-fruity fragrance ingredient in perfumes, cosmetics, cleaning products, and air fresheners. It is a colorless to pale yellow liquid commonly supplied for formulation and laboratory use; typical purity is 98.0%.
- Used as a floral-fruity fragrance ingredient in perfumes, cosmetics, and household products.
- Contributes lily-like, powdery top notes at low concentrations.
- High purity supports reproducible formulation and analytical testing.
- Liquid form facilitates incorporation into liquid and emulsion systems.
- Well-characterized chemical properties aid regulatory and safety assessment.
Medchemexpress LLC 2-(Dimethylphosphoryl)benzenamine | 1197953-47-1 | 169.16 | 100 G
2-(DiMethylphosphoryl)benzenamine is a chemical compound primarily used as a drug intermediate for the synthesis of various active pharmaceutical ingredients. It serves as a crucial building block in medicinal chemistry.
- High purity, ensuring reliable results in synthesis.
- Versatile intermediate for drug discovery.
- Available in quantities suitable for research and development.
Medchemexpress LLC 2'-bromo-2'-deoxyuridine | 4753-02-0 | MFCD06658226 | 96.9% | 307.1 g/mol | C9H11BrN2O5 | 10 MG
2'-Bromo-2'-deoxyuridine is a brominated nucleoside analog used as a research reagent for DNA synthesis and cell proliferation studies. It acts as a thymidine analog for incorporation into DNA and is supplied as a purified solid with reported HPLC purity of 96.92%.
- Brominated nucleoside analog for DNA incorporation studies.
- Used in cell proliferation and DNA replication assays.
- Supplied as a stable solid for laboratory use.
- High HPLC purity suitable for research applications.
- Compatible with standard molecular biology protocols.
Medchemexpress LLC N-Benzylhydroxylamine hydrochloride | 29601-98-7 | 159.62 | 100G
N-Benzylhydroxylamine hydrochloride is a chemical compound with the CAS number 29601-98-7 and a molecular weight of 159.62. It appears as a white to light yellow solid. This product has been tested and complies with the given specifications, showing a purity of 98.0% by NMR.
- CAS number: 29601-98-7
- Molecular formula: C7H10ClNO
- Molecular weight: 159.62
- Appearance: White to light yellow solid
- Purity (NMR): 98.0%
- Solid storage: 4°C, sealed, away from moisture
- In solvent storage: -80°C for 6 months; -20°C for 1 month, sealed, away from moisture
Medchemexpress LLC Ferroptosis-IN-21 (8-hydroxy-1,2,3,4-tetrahydroquinoline) | 6640-50-2 | 149.19 | 25 G
Ferroptosis-IN-21 is a ferroptosis inhibitor that protects against renal ischemia/reperfusion (I/R) injury. It acts by suppressing ferroptosis and directly scavenging peroxyl radicals, exhibiting broad-spectrum anti-ferroptotic efficacy and nanomolar potency in renal tubular epithelial cells.
- Exhibits nanomolar cytoprotective activity (EC50 = 61.7 nM) and reverses cell death
- Protects human kidney cells from induced ferroptosis
- Suppresses lipid Reactive Oxygen Species accumulation
- Demonstrates potent direct radical scavenging activity
- Ameliorates renal I/R injury in mice
- Reduces serum creatinine and blood urea nitrogen in I/R models
- Decreases lipid peroxidation biomarkers
- Useful for ferroptosis-targeted drug development research
Medchemexpress LLC OARV-771 | 2683008-37-7 | 98.8% | C49H59ClN8O8S2 | 25 MG
OARV-771 is a VHL-based BET degrader (PROTAC) with improved cell permeability. It shows DC50s of 6 nM for Brd4, 1 nM for Brd2, and 4 nM for Brd3. It also exhibits an antiproliferative effect with an EC50 value of 4 nM in MV4;11 cells.
- VHL-based BET degrader (PROTAC)
- Enhanced cell permeability
- Demonstrates DC50s of 6 nM for Brd4, 1 nM for Brd2, and 4 nM for Brd3
- Exhibits an antiproliferative effect with an EC50 value of 4 nM in MV4;11 cells
Apexbio Technology LLC Cyclobenzaprine HCl 6202-23-9 5g
Cyclobenzaprine HCl (CAS 6202-23-9) is a small molecule antagonist and inhibitor of the 5-HT2 receptor family exhibiting high affinity binding (Ki 62 nM) to 5-HT2 receptors and notably lower affinity for 5-HT1 receptors (Ki 2900 nM) 5-HT2 receptors comprising the 5-HT2A 5-HT2B and 5-HT2C subtypes are G protein-coupled receptors with significant roles in central nervous system signaling Cyclobenzaprine HCl has been shown to suppress both monosynaptic and polysynaptic reflex amplitudes in animal models and reduce neural firing rates suggesting inhibition of spinal reflex transmission through 5-HT2 receptor pathways This compound is utilized in neuroscience research to study serotonergic modulation of synaptic transmission and spinal reflexes
Aobchem 2-(3-Ethoxyphenyl)ethanol | ≥95% | CAS 1000521-80-1 | C10H14O2 | 1g
2-(3-Ethoxyphenyl)ethanol | ≥95% | CAS 1000521-80-1 | C10H14O2 | 1g
Aobchem 1-Bromo-4-isopropoxy-2-methoxybenzene | ≥97% | CAS 176391-61-0 | C10H13BrO2 | 5g
1-Bromo-4-isopropoxy-2-methoxybenzene | ≥97% | CAS 176391-61-0 | C10H13BrO2 | 5g