Phenols
Medchemexpress LLC Cloxiquine | 130-16-5 | 99.9% | 100 G
Cloxiquine (5-Chloro-8-quinolinol) is a versatile agent with antibacterial, antifungal, and antiamoebic properties. It is suitable for research concerning tuberculosis and dermatoses. This compound has demonstrated the ability to suppress the growth and metastasis of melanoma cells by activating PPARγ, and also exhibits antituberculosis activities against various strains of *Mycobacterium tuberculosis*.
- Antibacterial, antifungal, and antiamoebic agent.
- Used for tuberculosis and dermatoses research.
- Suppresses melanoma cell growth and metastasis by activating PPARγ.
- Exhibits antituberculosis activities with MICs ranging from 0.062 to 0.25 μg/mL.
- Inhibits migration of B16F10 and A375 cells.
- Suppresses glycolysis in B16F10 cells.
- Suppresses tumor growth in mouse melanoma xenograft model.
- Suppresses tumor metastasis in mouse melanoma lung metastatic model.
Medchemexpress LLC Clomiphene (citrate) | 50-41-9 | 98.2% | 5 G
Clomiphene citrate is an orally active estrogen-receptor modulator. It exhibits anti-cancer activity, induces perturbations during meiotic maturation and cytogenetic abnormalities, and helps in managing psychiatric and cognitive impairment.
- Exhibits anti-cancer activity
- Induces perturbations during meiotic maturation and cytogenetic abnormalities
- Ameliorates psychiatric and cognitive impairment
- Inhibits viability of human prostate cancer cells
- Induces chromosome abnormalities in mouse oocytes
- Shows anxiolytic potential and improved cognitive functions in PCOS models
Medchemexpress LLC Sodium Picosulfate | 10040-45-6 | MFCD00867640 | 98.0% | 1 ML
Sodium Picosulfate is a contact irritant laxative with oral activity. It inhibits the absorption of water and electrolytes, thereby increasing their production. Sodium Picosulfate can be used in colonoscopy applications. It is for research use only and not sold to patients.
- Contact irritant laxative with oral activity
- Inhibits the absorption of water and electrolytes
- Increases production of water and electrolytes
- Can be used in colonoscopy applications
- For research use only
Medchemexpress LLC Loxoprofen sodium | 80382-23-6 | 99.6% | 1 ML
Loxoprofen sodium is a non-steroidal, orally active anti-inflammatory agent with analgesic and anti-pyretic properties. It is a nonselective COX inhibitor with IC50s of 6.5 and 13.5 μM for COX-1 and COX-2, respectively. It can also reduce atherosclerosis and shows antitumor activity.
- Non-steroidal, orally active anti-inflammatory agent
- Analgesic and anti-pyretic properties
- Nonselective COX inhibitor
- Reduces atherosclerosis
- Shows antitumor activity
Medchemexpress LLC Edrophonium chloride | 116-38-1 | 99.39% | 100 MG
Edrophonium chloride is a short-acting acetylcholinesterase (AChE) inhibitor. It can be utilized to detect early digitalis toxicity and in the study of myasthenia gravis.
- Exhibits Ki values of 0.2, 0.2, and 0.4 μM for AChE in human erythrocytes, purified calf forebrain, and purified octopus brain, respectively.
- Shows IC50 values of 0.2, 0.05, and 0.5 μM for AChE in human erythrocytes, purified calf forebrain, and purified octopus brain, respectively.
- Inhibits DMPP-induced currents in Xenopus laevis oocytes expressing mouse muscle nicotinic acetylcholine receptor (nAChR) with an IC50 of 82.1 μM.
Medchemexpress LLC LysoFP-NO2 | 69408-75-9 | 98.2% | 1 MG
LysoFP-NO2 is a turn-on fluorescent probe for carbon monoxide (CO) that localizes to the lysosome. When lysosomal CO is present, LysoFP-NO2 transforms into lysoFP-NH2, which is highly fluorescent. It is selective for CO over various reactive nitrogen, oxygen, and sulfur species. It displays excitation/emission maxima of 440/528 nm and is not cytotoxic to HepG2 cells for up to five hours at a concentration of 30 μM.
- Turn-on fluorescent probe for carbon monoxide
- Localizes to the lysosome
- Highly fluorescent upon transformation in presence of lysosomal CO
- Selective for CO over reactive nitrogen, oxygen, and sulfur species
- Excitation/emission maxima of 440/528 nm
- Non-cytotoxic to HepG2 cells for up to five hours at 30 μM concentration
Medchemexpress LLC Methyltetrazine-Ph-NHS ester | 1644644-96-1 | 98.9% | 5 G
Methyltetrazine-Ph-NHS ester is an alkyl/ether-based PROTAC linker used in the synthesis of PROTACs. It is a click chemistry reagent containing a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
- Alkyl/ether-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains a Tetrazine group that undergoes an inverse electron demand Diels-Alder reaction (iEDDA) with TCO groups
- For research use only
Medchemexpress LLC Bis-NH2-PEG2 | 929-59-9 | 99.8% | 25 G
Bis-NH2-PEG2 (PROTAC Linker 19) is a PEG-based PROTAC linker that can be utilized in the synthesis of PROTACs. PROTACs consist of two different ligands connected by a linker; one ligand is for an E3 ubiquitin ligase and the other is for the target protein. They function by exploiting the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Facilitates the degradation of target proteins via the ubiquitin-proteasome system
Medchemexpress LLC Enrofloxacin (monohydrochloride) | 93106-59-3 | 99.7% | 5 G
Enrofloxacin monohydrochloride is an effective antibiotic that exhibits an MIC90 of 0.312 μg/mL against *Mycoplasma bovis*. It also demonstrates inhibitory activity against vaccinia virus (VV) and is intended for research use.
- Effective antibiotic
- Exhibits MIC90 of 0.312 μg/mL for Mycoplasma bovis
- Shows inhibitory activity against vaccinia virus (VV)
- High purity of 99.73%
- Recommended storage at 4°C, sealed, away from moisture
Medchemexpress LLC Cefoperazone sodium salt | 62893-20-3 | 99.55% | 5 G
Cefoperazone sodium salt is a semisynthetic cephalosporin with broad-spectrum antibacterial activity, intended for research use only. It appears as a white to off-white solid and is soluble in both DMSO and water.
- Exhibits broad-spectrum antibacterial activity
- Intended for research use only
- Soluble in DMSO and water
- Protects against acute Pseudomonas aeruginosa pneumonia in granulocytopenic mice
Medchemexpress LLC Ethambutol dihydrochloride | 1070-11-7 | 99.9% | 50 MG
Ethambutol dihydrochloride is an antimycobacterial compound that prevents cell wall formation by inhibiting arabinosyltransferase activity. It can be used to establish animal models of hyperuricemia and optic neuropathy. This product is for research use only and not sold to patients.
- Antimycobacterial compound
- Prevents cell wall formation by inhibiting arabinosyltransferase activity
- Used to establish animal models of hyperuricemia
- Used to establish animal models of optic neuropathy
Medchemexpress LLC Fosinopril sodium | 88889-14-9 | 99.2% | 1 ML
Fosinopril sodium is an ester prodrug of an angiotensin-converting enzyme (ACE) inhibitor. It is used for the treatment of hypertension and some types of chronic heart failure. This product is an analytical standard intended for research and analytical applications. It has a purity of 99.2%.
- Ester prodrug of an angiotensin-converting enzyme (ACE) inhibitor
- Treats hypertension
- Treats some types of chronic heart failure
- Intended for research and analytical applications
- Purity of 99.2%
Medchemexpress LLC Cloxiquine (5-Chloro-8-quinolinol) | 130-16-5 | 99.9% | 25 G
Cloxiquine (5-Chloro-8-quinolinol) is an antibacterial, antifungal, and antiamoebic agent. It can be used for the research of tuberculosis and dermatoses, and suppresses the growth and metastasis of melanoma cells through the activation of PPARγ.
- Antibacterial, antifungal, and antiamoebic properties
- Suitable for tuberculosis and dermatoses research
- Suppresses growth and metastasis of melanoma cells
- Exhibits antituberculosis activities with low MICs
- Inhibits migration of B16F10 and A375 cells
- Suppresses glycolysis in B16F10 cells
- Proven to suppress tumor growth in mouse models
- Demonstrated to suppress tumor metastasis in mouse models
Medchemexpress LLC Oxacillin (sodium monohydrate) | 7240-38-2 | 99.6% | 500 MG
Oxacillin sodium monohydrate is an antibiotic similar to Flucloxacillin, utilized in the study of resistant staphylococci infections. It is a white to off-white solid, stable under recommended storage conditions, and intended for research use only.
- Similar to Flucloxacillin
- Used in resistant staphylococci infections study
- Intended for research use only
- Stable under recommended storage conditions
- Ships at room temperature (if less than 2 weeks)
Medchemexpress LLC Rabeprazole sodium | 117976-90-6 | 99.9% | 1 ML
Rabeprazole sodium (LY307640 sodium) is provided as a 10 mM solution in 1 mL of DMSO. It is a second-generation proton pump inhibitor (PPI) that irreversibly inactivates gastric H+/K+-ATPase. This compound induces apoptosis and acts as an uridine nucleoside ribohydrolase (UNH) inhibitor with an IC50 of 0.3 μM. It is suitable for research on gastric ulcerations and gastroesophageal reflux and is intended for research use only.
- Second-generation proton pump inhibitor (PPI)
- Irreversibly inactivates gastric H+/K+-ATPase
- Induces apoptosis
- Acts as an uridine nucleoside ribohydrolase (UNH) inhibitor with an IC50 of 0.3 μM
- Suitable for research on gastric ulcerations and gastroesophageal reflux