Phenols
Apexbio Technology LLC Pilocarpine HCl(Synonyms: Pilocarpine hydrochloride, Salagen, Pilocar, Isopto Carpine), 10mM (in 1mL DMSO), CAS: 54-71-7.
Pilocarpine HCl (CAS 54-71-7) the hydrochloride salt form of pilocarpine is a nonselective muscarinic acetylcholine receptor agonist derived from plants of the Pilocarpus genus By directly activating muscarinic receptors pilocarpine promotes exocrine gland secretion induces contraction of smooth muscle tissues and when applied ocularly triggers miosis and ciliary muscle contraction enhancing aqueous humor drainage and reducing intraocular pressure In biomedical research pilocarpine is employed widely to induce rodent epilepsy models and to study cholinergic mechanisms underlying secretory processes
Medchemexpress LLC Tianeptine (sodium salt) | 30123-17-2 | 99.9% | C21H24ClN2NaO4S | 1 ML
Tianeptine sodium salt, with chemical formula C21H24ClN2NaO4S and CAS number 30123-17-2, is provided as a 10 mM solution in 1 mL of DMSO. This ready-to-use format is designed for various research applications, including both in vitro and in vivo studies.
- Ready-to-use 10 mM solution in DMSO
- Ideal for in vitro and in vivo research applications
- Recommended storage at -80°C for 6 months or -20°C for 1 month in solvent
- High chemical purity of the active compound
Medchemexpress LLC Methenamine (hippurate) | 5714-73-8 | 99.7% | 25 MG
Methenamine (hippurate) (Standard) is the analytical standard of Methenamine (hippurate) and is intended for research and analytical applications. Methenamine hippurate (Hexamine hippurate) is an orally active urinary antiseptic agent with a wide antibacterial spectrum, effective against most common urinary tract pathogens. The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
- Intended for research and analytical applications
- Orally active urinary antiseptic agent
- Wide antibacterial spectrum
- Effective against most common urinary tract pathogens
- Used in HPLC, GC and MS research experiments
Medchemexpress LLC (-)-Menthone | 14073-97-3 | 100 G
(-)-Menthone is a monoterpene component found in the essential oil of maturing peppermint. It serves as a precursor to (+)-Neomenthyl-β-d-glucoside and has shown efficacy in affecting the mortality of *Anopheles stephensi* larvae.
- Purity: 98.0%
- Appearance: Liquid
- Color: Colorless to light yellow
- Molecular weight: 154.25
- Formula: C10H18O
- Melting/freezing point: -6°C
- Flash point: 72°C
- Density: 0.893 g/cm3
- Classification: Ketones, aldehydes, acids
- Initial source: Plants other families
eMolecules 487-68-3 | 2,4,6-Trimethylbenzaldehyde | Oakwood Chemical | MFCD00003341 | 148.205 | C10H12O | 95.000 | Cc1cc(C)c(C=O)c(C)c1 | 25g | 537714074
2,4,6-Trimethylbenzaldehyde | Oakwood Chemical | 487-68-3 | MFCD00003341 | 148.205 | C10H12O | 95.000 | Cc1cc(C)c(C=O)c(C)c1 | 25g | 537714074
eMolecules 950670-18-5 | 3-Bromo-5-fluoropicolinonitrile | Combi-Blocks | MFCD16988825 | 200.998 | C6H2BrFN2 | 97.000 | Fc1cnc(C#N)c(Br)c1 | 100g | 335344864
3-Bromo-5-fluoropicolinonitrile | Combi-Blocks | 950670-18-5 | MFCD16988825 | 200.998 | C6H2BrFN2 | 97.000 | Fc1cnc(C#N)c(Br)c1 | 100g | 335344864
![eMolecules 1051375-19-9 | Dolutegravir sodium | Ambeed | MFCD28405599 | 441.367 | C20H18F2N3NaO5 | 99.000 | [Na+].C[C@@H]1CCO[C@H]2Cn3cc(C(=O)NCc4ccc(F)cc4F)c(=O)c([O-])c3C(=O)N12 | 5g | 552517129](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000188547.jpg-250.jpg)
eMolecules 1051375-19-9 | Dolutegravir sodium | Ambeed | MFCD28405599 | 441.367 | C20H18F2N3NaO5 | 99.000 | [Na+].C[C@@H]1CCO[C@H]2Cn3cc(C(=O)NCc4ccc(F)cc4F)c(=O)c([O-])c3C(=O)N12 | 5g | 552517129
Dolutegravir sodium | Ambeed | 1051375-19-9 | MFCD28405599 | 441.367 | C20H18F2N3NaO5 | 99.000 | [Na+].C[C@@H]1CCO[C@H]2Cn3cc(C(=O)NCc4ccc(F)cc4F)c(=O)c([O-])c3C(=O)N12 | 5g | 552517129
Medchemexpress LLC Cloxiquine | 130-16-5 | 99.9% | 100 G
Cloxiquine (5-Chloro-8-quinolinol) is a versatile agent with antibacterial, antifungal, and antiamoebic properties. It is suitable for research concerning tuberculosis and dermatoses. This compound has demonstrated the ability to suppress the growth and metastasis of melanoma cells by activating PPARγ, and also exhibits antituberculosis activities against various strains of *Mycobacterium tuberculosis*.
- Antibacterial, antifungal, and antiamoebic agent.
- Used for tuberculosis and dermatoses research.
- Suppresses melanoma cell growth and metastasis by activating PPARγ.
- Exhibits antituberculosis activities with MICs ranging from 0.062 to 0.25 μg/mL.
- Inhibits migration of B16F10 and A375 cells.
- Suppresses glycolysis in B16F10 cells.
- Suppresses tumor growth in mouse melanoma xenograft model.
- Suppresses tumor metastasis in mouse melanoma lung metastatic model.
Medchemexpress LLC Cuminaldehyde (p-isopropylbenzaldehyde) | 122-03-2 | MFCD00006953 | 99.3% | 148.21 g/mol | C10H12O | 100g
Cuminaldehyde is the main component of Cuminum cyminum and has multiple biological activities including anti-inflammatory anti-cancer anti-diabetic anti-injury anti-neuropathy and antibacterial effects Cuminaldehyde is an inhibitor of aldose reductase (IC50 0 00085 mg/mL) -glucosidase (IC50 0 5 mg/mL) and lipoxygenase (IC50 1370 M) Cuminaldehyde also inhibits the fibrillation of -synuclein and prevents its aggregation Cuminaldehyde has potential application value in the research of neurodegenerative diseases cancer diabetes and neuropathic pain diseases[1][2][3][4][5][6][7]
![Medchemexpress LLC 4-(trifluoromethoxy)-N-[[2-(trifluoromethyl)phenyl]methyl]-benzenecarboximidamide | 305339-41-7 | 99.8% | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000232954.png-250.jpg)
Medchemexpress LLC 4-(trifluoromethoxy)-N-[[2-(trifluoromethyl)phenyl]methyl]-benzenecarboximidamide | 305339-41-7 | 99.8% | 1 ML
BZAD-01 is a potent, selective, orally active inhibitor of the NMDA receptor NR2B subunit (reported Ki = 72 nM). It is supplied as a solid (white to off-white) and as a 10 mM stock solution in DMSO.
- Potent, selective NR2B inhibitor (Ki = 72 nM).
- Molecular formula C16H12F6N2O; molecular weight 362.27.
- High purity (approximately 99.8%).
- Available as solid and as 10 mM solution in DMSO (1 mL).
- Storage: solid at 4°C, protect from light; stock solutions -80°C up to 6 months or -20°C up to 1 month, protect from light.
- Suitable for in vitro pharmacology and in vivo NR2B-related studies.
Medchemexpress LLC Zika virus E/envelope protein (HEK293, His) | >95.0% | 5 UG
Recombinant Zika virus E (envelope) protein expressed in HEK293 cells, supplied lyophilized for use in immunoassays, antibody validation, and serology research. The protein includes a C-terminal His tag and corresponds to envelope domain V593-K699 (≈13 kDa), provided in small-format quantities suitable for assay development.
- Recombinant expression in HEK293 mammalian cells.
- C-terminal His tag for detection and purification.
- Domain V593-K699 of the envelope protein, sequence verified.
- Purity >95% by reducing SDS-PAGE.
- Lyophilized formulation from PBS, pH 7.4.
- Store at -20°C; after reconstitution stable at 4°C for 1 week.
![Medchemexpress LLC 3-Piperidineacetic acid, 1-[5-[(cyclohexylamino)carbonyl]-6-(propylthio)-2-pyridinyl]-, (3S)- | 1024033-43-9 | 99.2% | 419.58 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000384103-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 3-Piperidineacetic acid, 1-[5-[(cyclohexylamino)carbonyl]-6-(propylthio)-2-pyridinyl]-, (3S)- | 1024033-43-9 | 99.2% | 419.58 | 25 MG
AZD 4017 is a potent, selective 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1) inhibitor, with an IC50 of 7 nM. It is for research use only.
- Potent, selective 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with an IC50 of 7 nM.
- Displays excellent selectivity versus related enzymes such as 11-βHSD2, 17β-HSD1, 17β-HSD3 (all IC50 > 30 μM).
- Shows no measurable activity against glucocorticoid and mineralocorticoid receptors.
- Potent inhibitor of 11β-HSD1 activity in isolated human adipocytes from nondiabetic volunteers, with an IC50 of 0.002 μM.
- Appearance: solid.
- Color: light yellow to yellow.
![Alkali Scientific TRIS Hydrochloride [Tris(hydroxymethyl) aminomethane HCl], 500 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000659762.jpg-250.jpg)
Alkali Scientific TRIS Hydrochloride [Tris(hydroxymethyl) aminomethane HCl], 500 G
TRIS Hydrochloride (Tris(hydroxymethyl) aminomethane HCl) is an essential biochemical reagent used for a variety of laboratory applications. The 500g package offers a moderate supply for most research labs engaged in molecular biology, biochemistry, and enzyme assays. TRIS Hydrochloride plays a crucial role in buffer preparations for experiments such as PCR, protein electrophoresis, and DNA/RNA extraction. Its ability to stabilize the pH of solutions makes it indispensable for maintaining optimal conditions for enzymatic reactions. This reagent is also commonly used in the formulation of TAE and TBE buffers for agarose gel electrophoresis and in various other biochemistry experiments.
Medchemexpress LLC GM-CSF 100ug | 100ug
GM-CSF R alpha is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2 GM-CSF R alpha binds to the cytokine with high specificity and low affinity[1] GM-CSF R alpha binds to GM-CSF and induces cell differentiation[2] GM-CSF R alpha monoclonal antibody decreases GM-CSFR expression on GM-CSF-responsive cells and shows anti-inflammatory activity in rheumatoid arthritis (RA)[3] GM-CSF R alpha Protein Human (Biotinylated HEK293 His-Avi) is a biotinylated recombinant protein with a C-Terminal His label and a C-Terminal Avi label It consists of 298 amino acids (E23-G320) and is produced in HEK293 cells
Medchemexpress LLC ARD-2051 | 2632305-17-8 | 98.6% | 789.32 | 50 MG
ARD-2051 is a selective and orally active proteolysis-targeting chimera (PROTAC) degrader targeting the androgen receptor (AR). It effectively degrades AR protein with DC50 values of 0.6 nM in prostate cancer cell lines (LNCaP and VCaP) and shows significant anti-tumor activity in VCaP xenograft mouse models, making it suitable for prostate cancer research.
- Selective and orally active PROTAC degrader
- Targets the androgen receptor (AR)
- Induces AR protein degradation (DC50 of 0.6 nM in LNCaP and VCaP cells)
- Inhibits cell growth (IC50 of 12.8 nM in LNCaP, 10.2 nM in VCaP)
- Suppresses expression of the AR-regulated gene KLK3
- Demonstrates anti-tumor activity in VCaP xenograft mice models