Phenols
Medchemexpress LLC Seltorexant (hydrochloride) | 1293284-49-7 | 99.9% | 443.91 | 5 MG
Seltorexant hydrochloride is an orally active, high-affinity, and selective OX2R antagonist. It has pKi values of 8.0 and 8.1 for human and rat OX2R, respectively. This compound crosses the blood-brain barrier and quickly occupies OX2R binding sites in the rat brain. It is intended for research use only.
- Orally active, high-affinity, and selective OX2R antagonist
- pKi values of 8.0 for human OX2R and 8.1 for rat OX2R
- Crosses the blood-brain barrier
- Quickly occupies OX2R binding sites in the rat brain
- For research use only
Medchemexpress LLC Minocycline hydrochloride | 13614-98-7 | 99.7% | 493.94 | 5 G
Minocycline hydrochloride | 13614-98-7 | 99.7% | 493.94 | 5 G
Medchemexpress LLC Guretolimod hydrochloride | 00-00-0 | 98.7% | 550.01 | C24H35ClF3N5O4 | 5 MG
Guretolimod hydrochloride is a synthetic small-molecule Toll-like receptor 7 (TLR7) agonist supplied for research use. It is used in preclinical studies to stimulate innate immune signaling and evaluate immunostimulatory and antitumor responses in vitro and in vivo models.
- Potent TLR7 agonist for immune activation studies.
- Suitable for in vitro and in vivo preclinical research.
- High purity (approximately 98.7%) for consistent results.
- Hydrochloride salt form to improve solubility and handling.
- Characterized chemical identity with molecular formula C24H35ClF3N5O4 and molecular weight 550.01.
Ambeed 1R 3S 5R 2 tertButoxycarbonyl
(1R,3S,5R)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic acid, 197142-34-0, 97%
eMolecules 30830-27-4 | 3-(Benzyloxy)cyclobutanone | Ambeed | MFCD09755991 | 176.215 | C11H12O2 | 97.000 | O=C1CC(C1)OCc1ccccc1 | 10g | 524996685
3-(Benzyloxy)cyclobutanone | Ambeed | 30830-27-4 | MFCD09755991 | 176.215 | C11H12O2 | 97.000 | O=C1CC(C1)OCc1ccccc1 | 10g | 524996685
eMolecules 288315-03-7 | 3,3-difluoroazetidine hydrochloride | Pharmablock | MFCD05663714 | 129.530 | C3H6ClF2N | 97.000 | Cl.FC1(F)CNC1 | 10g | 551053263
3,3-difluoroazetidine hydrochloride | Pharmablock | 288315-03-7 | MFCD05663714 | 129.530 | C3H6ClF2N | 97.000 | Cl.FC1(F)CNC1 | 10g | 551053263
eMolecules 58885-58-8 | 3-(tert-Butoxycarbonylamino)-1-propanol | Ambeed | MFCD00191883 | 175.228 | C8H17NO3 | 97.000 | CC(C)(C)OC(=O)NCCCO | 25g | 525116051
3-(tert-Butoxycarbonylamino)-1-propanol | Ambeed | 58885-58-8 | MFCD00191883 | 175.228 | C8H17NO3 | 97.000 | CC(C)(C)OC(=O)NCCCO | 25g | 525116051
![eMolecules 262852-11-9 | 3-(trifluoromethyl)bicyclo[1.1.1]pentan-1-amine hydrochloride | Pharmablock | MFCD22056474 | 187.590 | C6H9ClF3N | 97.000 | Cl.NC12CC(C1)(C2)C(F)(F)F | 25g | 698446329](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000472318.jpg-250.jpg)
eMolecules 262852-11-9 | 3-(trifluoromethyl)bicyclo[1.1.1]pentan-1-amine hydrochloride | Pharmablock | MFCD22056474 | 187.590 | C6H9ClF3N | 97.000 | Cl.NC12CC(C1)(C2)C(F)(F)F | 25g | 698446329
3-(trifluoromethyl)bicyclo[1.1.1]pentan-1-amine hydrochloride | Pharmablock | 262852-11-9 | MFCD22056474 | 187.590 | C6H9ClF3N | 97.000 | Cl.NC12CC(C1)(C2)C(F)(F)F | 25g | 698446329
eMolecules 72187-91-8 | 2-Aminopropanenitrile hydrochloride | Ambeed | MFCD09971651 | 106.550 | C3H7ClN2 | 95.000 | Cl.CC(N)C#N | 5g | 752811086
2-Aminopropanenitrile hydrochloride | Ambeed | 72187-91-8 | MFCD09971651 | 106.550 | C3H7ClN2 | 95.000 | Cl.CC(N)C#N | 5g | 752811086
Medchemexpress LLC PF-06815345 hydrochloride | 2334434-49-8 | 98.15% | 634.49 | 10 MG
PF-06815345 hydrochloride is an orally active and potent inhibitor of proprotein convertase subtilisin/kexin type 9 (PCSK9) with an IC50 value of 13.4 μM. It significantly decreases the PCSK9 level in vivo in mouse. A clinical trial (NCT02654899) sponsored by Pfizer for Hypercholesterolemia started in November 2015 and is in Phase 1.
- Potent PCSK9 inhibitor with an IC50 of 13.4 μM.
- Significantly decreases PCSK9 levels in vivo.
- Shows CLint values of <82.9 μL/min/mg in human enterocytes and 97.6 μL/min/mg in human hepatocytes.
- Lowers plasma PCSK9 by 72% at 500 mg/kg in a humanized PCSK9 mouse model.
Medchemexpress LLC H3R antagonist 1 hydrochloride | 2319790-07-1 | 377.87 | 1 ML
H3R antagonist 1 hydrochloride is a histamine receptor 3 (H3R) inverse agonist that can be utilized for the study of multiple sclerosis. It increases the expression levels of myelin-associated glycoprotein (MAG) and myelin basic protein (MBP) in differentiating oligodendrocytes, promoting oligodendrocyte precursor cell (OPC) differentiation in vitro.
- Promotes oligodendrocyte precursor cell (OPC) differentiation
- Increases expression of myelin-associated glycoprotein (MAG) and myelin basic protein (MBP)
- Enhances remyelination in demyelination models
- Increases Forskolin-stimulated cAMP level in primary OPCs
Medchemexpress LLC Blarcamesine hydrochloride | 195615-84-0 | MFCD30146449 | 99.9% | 317.85 g/mol | C19H24ClNO | 50 MG
Blarcamesine hydrochloride is the hydrochloride salt of blarcamesine, a small-molecule Sigma-1 receptor agonist supplied as a research-grade solid for in vitro and preclinical studies. It is provided with characterization data and handling guidance for sealed storage; reported activity includes an IC50 ≈ 860 nM at the Sigma-1 receptor.
Medchemexpress LLC Ticlopidine hydrochloride | 53885-35-1 | 99.99% | 5 G
Ticlopidine hydrochloride is an antithrombotic proagent that acts as an allosteric, noncompetitive inhibitor of CD39 with an IC50 of 81.7 μM. It blocks several NTPDase isoenzymes, with IC50s of 170 μM for NTPDase2 and 149 μM for NTPDase3. This compound also inhibits CYP2C19 human liver cytochrome, as well as CYP2C9 and CYP3A4 with IC50s of 26.0 and 32.3 μM, respectively.