Rebaudioside M is a non-calorie sweetener isolated from Stevia rebaudiana. This glycoside of the ent-kaurene diterpenoid aglycone is over 350 times sweeter than sucrose and is suitable for use in food and beverages. It has also been observed to provide antidiabetic, antihypertensive, anti-inflammatory, antioxidant, anticaries, and anticancer benefits.
- Protects beta-cell activity and enhances insulin secretion
- Inhibits the PI3K/Akt signaling pathway
- Downregulates the Wnt/catenin signaling pathway in colon cancer cells
- Lowers fasting blood glucose and enhances glucose tolerance
- Decreases oxidative stress and pro-inflammatory cytokines
- Reduces blood pressure and increases endothelial function