Capmatinib dihydrochloride is the dihydrochloride salt of capmatinib, a potent, selective, ATP-competitive inhibitor of the c-MET tyrosine kinase for preclinical research. It inhibits c-MET phosphorylation and downstream effectors, suppressing c-MET-dependent tumor cell proliferation and migration.
- Potent c-MET kinase inhibitor with low nanomolar activity.
- Inhibits downstream signaling pathways involved in proliferation and survival.
- Supplied as a dihydrochloride salt to aid solubility for assays.
- High purity (99.8%) suitable for analytical and biological studies.
- Available in small pack sizes for laboratory research use.
- Molecular weight 485.34 g/mol; formula C23H19Cl2FN6O.