Phenols
Medchemexpress LLC ζ-Stat trisodium | 31894-34-5 | 97.0% | 450.31 g·mol⁻¹ | C10H5Na3O10S3 | 100MG
ζ-Stat trisodium is the trisodium salt of NSC37044 and a selective, atypical protein kinase C zeta (PKC-ζ) inhibitor reported to have an IC50 of approximately 5 μM. It has demonstrated in vitro antitumor activity, including reduced proliferation and induced apoptosis in melanoma cell lines. This research chemical is supplied as a solid with reported purity of 97.0%.
- Selective PKC-ζ inhibitor; IC50 ≈ 5 μM.
- Demonstrated reduction of melanoma cell proliferation in vitro.
- Reported to induce apoptosis in cancer cell lines.
- Provided as a light yellow solid for research use.
- High purity: 97.0%.
- Molecular weight 450.31 g·mol⁻¹; formula C10H5Na3O10S3.
- Available in 100 mg research quantities.
Medchemexpress LLC Ard-2051 | 2632305-17-8 | 98.6% | 789.32 | C43H45ClN8O5 | 10 MG
ARD-2051 is a selective, orally active androgen receptor proteolysis-targeting chimera (PROTAC) degrader developed for preclinical research into AR-dependent cancers. It induces potent AR protein degradation in cell-based assays and has demonstrated favorable pharmacokinetics and oral efficacy in animal models.
- Potent AR protein degradation (DC50 ~0.6 nM).
- Orally active with demonstrated in vivo efficacy in preclinical models.
- Effective in AR-positive prostate cancer cell lines, including LNCaP and VCaP.
- Characterized pharmacokinetic profile and oral bioavailability in rodent and canine studies.
- High chemical purity suitable for research applications.
- Supplied as a solid with defined storage recommendations for stability.
Medchemexpress LLC Calcitonin/CALCA Mo 100ug | 100ug
The Calcitonin/CALCA protein induces vasodilation in different blood vessels including the coronary cerebral and systemic vasculature It is highly concentrated in the central nervous system suggesting a role as a neurotransmitter or neuromodulator Moreover it increases platelet cAMP levels possibly affecting platelet function Calcitonin/CALCA Protein Mouse (HEK293 Fc) is the recombinant mouse-derived Calcitonin/CALCA protein expressed by HEK293 with C-hFc labeled tag
Medchemexpress LLC Acridone | 578-95-0 | 195.22 | 100 G
Acridone is an organic compound derived from the acridine skeleton, known for its diverse biological activities. It has been observed to possess antibacterial, antimalarial, antiviral, and anti-neoplastic properties. This versatile compound has also been shown to inhibit the proliferation of human breast cancer cells in vitro and to block the expression of ATP binding cassette subfamily G member 2 (ABCG2) at both mRNA and protein levels, highlighting its potential in various research applications.
- Organic compound based on the acridine skeleton.
- Exhibits antibacterial properties.
- Possesses antimalarial activity.
- Demonstrates antiviral effects.
- Shows anti-neoplastic activities.
- Inhibits proliferation of human breast cancer cells.
- Blocks expression of ATP binding cassette subfamily G member 2 (ABCG2).
eMolecules 1191-95-3 | Cyclobutanone | Apollo Scientific | MFCD00001332 | 70.091 | C4H6O | 98.000 | O=C1CCC1 | 5g | 600855777
Cyclobutanone | Apollo Scientific | 1191-95-3 | MFCD00001332 | 70.091 | C4H6O | 98.000 | O=C1CCC1 | 5g | 600855777
Medchemexpress LLC Fluorescein di(β-D-galactopyranoside) | 17817-20-8 | MFCD00077344 | ≥98.0% | 656.59 g/mol | C32H32O15 | 10 MG
Fluorescein di(β-D-galactopyranoside) is a fluorogenic substrate for β-galactosidase that releases fluorescein upon enzymatic hydrolysis, producing a fluorescent signal suitable for detecting enzyme activity in cells and biochemical assays. Store at -20°C and protect from light; the compound is unstable in solution and should be freshly prepared.
- Fluorogenic substrate for β-galactosidase.
- Generates fluorescein with excitation ~488 nm and emission ~520-535 nm.
- Compatible with flow cytometry, fluorescence microscopy, and plate-reader assays.
- Molecular formula C32H32O15; molecular weight 656.59 g/mol.
- Pack sizes suitable for small-scale research use; handle protected from light.
Medchemexpress LLC N-(4-(2-tert-butylphenyl)sulfonylphenyl)-2,3,4-trihydroxy-5-(2-isopropylbenzyl)benzamide | 877877-35-5 | 99.5% | 1 ML
TW-37 is a small-molecule BH3 mimetic that inhibits anti-apoptotic Bcl-2 family proteins and is used in apoptosis and oncology research. Supplied as a ready-to-use 10 mM solution in DMSO (1 mL), it is intended for research use only.
- Ready-to-use 10 mM solution in DMSO, 1 mL.
- Potent inhibition of Bcl-2 family proteins with Ki values: Mcl-1 260 nM; Bcl-2 290 nM; Bcl-xL 1,110 nM.
- Molecular formula: C33H35NO6S; molecular weight: 573.7 g·mol⁻1.
- High purity (99.5%) suitable for research applications.
- Intended for in vitro research use; not for clinical or therapeutic use.
Medchemexpress LLC ssPA protein, E. coli (His) | >95.0% | 10 UG
Recombinant ssPA (SspA) protein expressed in Escherichia coli with an N-terminal His tag. Supplied as a lyophilized sterile powder, the protein forms an equimolar complex with RNA polymerase holoenzyme and is useful for biochemical, structural, and functional studies. The product is high purity with low endotoxin and is recommended to be stored frozen and aliquoted after reconstitution.
- Expressed in E. coli with an N-terminal His tag.
- Supplied as lyophilized sterile powder for long-term stability.
- Greater than 95.0% purity by reducing SDS-PAGE.
- Low endotoxin level (<1 EU/μg) suitable for sensitive assays.
- Includes full-length sequence and recommended storage instructions.
Medchemexpress LLC MePhos | 251320-86-2 | 98.0% | 364.50 | 25 G
MePhos is an o-BPP ligand. The combination of MePhos and silver carbonate serves as a catalyst for H/D exchange reactions.
- Designed as an o-BPP ligand
- Can be used with silver carbonate as a catalyst
- Facilitates H/D exchange reactions
Medchemexpress LLC Galaxolide 100g
Galaxolide can induce estrogenic activity (Estrogen Receptor/ERR) trigger oxidative stress and genotoxicity and induce EROD and GST (Glutathione S-transferase) enzyme activity[1][2]
Apexbio Technology LLC GM 6001 142880-36-2 5mg
GM 6001 (Ilomastat Galardin CAS 142880-36-2) is a broad-spectrum inhibitor of matrix metalloproteinases (MMPs) including MMP-1 -2 -3 -8 and -9 with reported Ki values of 0 4 nM 0 5 nM 27 nM 0 1 nM and 0 2 nM respectively MMPs participate in extracellular matrix remodeling and mediate signaling events induced by GPCR agonists through EGFR transactivation GM 6001 suppresses EGFR phosphorylation ERK activation and subsequent DNA synthesis induced by stimuli such as bombesin and lysophosphatidic acid (LPA) Additionally this compound has potential applications in cartilage research facilitating meniscal repair under inflammatory conditions by dampening IL-1-mediated MMP activity
Medchemexpress LLC Ethylparaben | 120-47-8 | 99.5% | 25 G
Ethylparaben is the ethyl ester of paraben and is used as an antifungal preservative and food additive. It exhibits antibacteria and antifungal activities against various microbes.
- Used as an antifungal preservative
- Used as a food additive
- Shows antibacteria and antifungal activities
Medchemexpress LLC Suberoyl bis-hydroxamic acid | 38937-66-5 | 95.0% | 204.22 | 10 MM 1 ML
Suberoyl bis-hydroxamic acid | 38937-66-5 | 95.0% | 204.22 | 10 MM 1 ML
Medchemexpress LLC 1,2-bis(2,4,6-tribromophenoxy)ethane-13C12 | 2724878-45-7 | MFCD00071811 | 699.55 | C14H8Br6O2 | 1mg
1 2-Bis(2 4 6-tribromophenoxy)ethane-13C12 is 13C labeled 1 1-(1 2-Ethanediylbis(oxy))bis(2 4 6-tribromobenzene)[1]
Medchemexpress LLC Br-PEG4-OH | 85141-94-2 | 98.2% | 5 G
Br-PEG4-OH is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs consist of two different ligands linked together; one targets an E3 ubiquitin ligase and the other targets the protein of interest. Their function is to leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Peg-based protac linker
- Utilized in the synthesis of protacs
- Leverages the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins