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Aromatic organic compounds that consist of a phenyl functional group (−C6H5) bonded to a hydroxyl functional group (−OH). Includes compounds with more substitutions and derivatives.
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The GM-CSF protein acts as a potent cytokine that coordinates the growth and differentiation of hematopoietic precursor cells of different lineages including granulocytes macrophages eosinophils and erythrocytes Structurally GM-CSF exists as a monomer and its signaling is mediated through a dodecamer complex GM-CSF Protein Mouse (HEK293 Fc) is the recombinant mouse-derived GM-CSF protein expressed by HEK293 with N-hFc labeled tag
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Cucurbitacin E is a natural compound sourced from Cucurbitaceae plants. It significantly suppresses the activity of the cyclin B1/CDC2 complex and is intended for research use only. This compound exhibits growth inhibition in various cancer cell lines and reduces obesity in mice by targeting the JAK-STAT5 signaling pathway.
Natural compound from Cucurbitaceae plants.
Significantly suppresses the activity of the cyclin B1/CDC2 complex.
Exhibits growth inhibition in various cancer cell lines including human prostate, CNS, breast, colon, HL-60, HSC-T6, HT-1080, HeLa, HepG2, JY, MCF7, and U-937 cells.
Induces morphological changes in primary colon cancer cells and inhibits tumor growth by arresting the cell cycle in the G2/M phase.
Reduces obesity and related metabolic dysfunction in mice.
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Bromo-PEG1-C2-azide is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent due to its Azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups.
PEG-based PROTAC linker
Utilized in PROTAC synthesis
Click chemistry reagent with Azide group
Reacts with Alkyne groups via CuAAc
Reacts with DBCO or BCN groups via SPAAC
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G0-C14 is a cationic lipid-like compound, an alkyl-modified polyamidoamine (PAMAM) dendrimer. It is utilized in the preparation of macrophage-targeted nanoparticles (NPs) for agent and vaccine delivery.
Strong entrapment of mRNA and pDNA with over 95% encapsulation efficiency.
Appears as an oil.
Colorless to light yellow in appearance.
Purity of 98.0%.
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2-Bromo-2'-methoxyacetophenone is an irreversible inhibitor for MurA, inhibiting MurA in *E. coli* with an IC50 of 0.38 μM. It can be used in antibacterial research for blocking bacterial cell wall synthesis.
Inhibits MurA in *E. coli* with an IC50 of 0.38 μM.
Used in antibacterial research.
Blocks bacterial cell wall synthesis.
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Ethylenediaminetetraacetic acid (EDTA) tetrasodium is a kind of metal chelating agent (binds to bivalent and trivalent metal cations including calcium) Ethylenediaminetetraacetic acid tetrasodium has antibacterial anti-inflammatory antioxidant anti-hypercalcemia and anticoagulant activities Ethylenediaminetetraacetic acid tetrasodium decreases the metal ion-catalyzed oxidative damage to proteins and allows maintenance of reducing environment during protein purification Ethylenediaminetetraacetic acid tetrasodium can alleviate the liver fibrosis Ethylenediaminetetraacetic acid tetrasodium can be used for coronary artery disease and neural system disease research[1][2][3][4][5][6][7]
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Tetrahydro-11-deoxycortisol is an endogenous urinary steroid metabolite supplied as a research reference standard for studies of 11β-hydroxylase deficiency and steroid metabolism. It is provided as a white to off-white solid suitable for analytical and biochemical applications.
High purity (>98.2% by HPLC).
Suitable as a reference standard for steroid metabolism and diagnostic research.
Solid form for accurate weighing and analytical preparation.
Molecular formula C21H34O4; molecular weight 350.49 g·mol⁻¹.
Available in small-quantity vials for method development and validation.
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I-191 is a potent PAR2 antagonist that inhibits multiple PAR2-induced signaling pathways and functional responses I-191 also inhibits ERK1/2 phosphorylation RhoA activation and inhibition of forskolin-stimulated cAMP accumulation induced by micromolar concentrations of biased ligand GB88
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Oxindole (Indolin-2-one) is an aromatic heterocyclic building block 2-indolinone derivatives have become lead compounds in the research of kinase inhibitors
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Varenicline dihydrochloride is a small-molecule partial agonist of neuronal nicotinic acetylcholine receptors, used as a research reagent to study α4β2, α6β2, and α7 receptor pharmacology and mechanisms of nicotine dependence. The dihydrochloride salt improves aqueous solubility for in vitro assays and analytical workflows.
Potent partial agonist of α4β2 nicotinic receptors.
Also active at α6β2 and α7 receptor subtypes.
Suitable for in vitro pharmacology and signaling studies.
High reported purity appropriate for research use.
Dihydrochloride salt enhances solubility in aqueous media.
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Bromophenol blue sodium salt is a water-soluble pH indicator and tracking dye used as a biochemical assay reagent. It is supplied as a brown to dark brown solid and is commonly used as a tracking dye in nucleic acid and protein electrophoresis, and as a pH indicator in buffer systems.
cas number: 34725-61-6
chemical formula: C19H9Br4NaO5S
molecular weight: 691.94 g/mol
appearance: solid, brown to dark brown
solubility: soluble in DMSO (100 mg/mL with ultrasonic warming)