Carboxylic acids and derivatives
eMolecules 500788-85-2 | Boc-(R)-3-amino-3-(2-methoxyphenyl)propionic acid | Chem-Impex | MFCD02090692 | 295.335 | C15H21NO5 | 98.000 | COc1ccccc1C(CC(O)=O)NC(=O)OC(C)(C)C | 1g | 112747767
Boc-(R)-3-amino-3-(2-methoxyphenyl)propionic acid | Chem-Impex | 500788-85-2 | MFCD02090692 | 295.335 | C15H21NO5 | 98.000 | COc1ccccc1C(CC(O)=O)NC(=O)OC(C)(C)C | 1g | 112747767
Sigma Aldrich Fine Chemicals Biosciences Ethyl 4-bromocrotonate 75%, technical grade | Purity: 75% | Mol Wt: 193.04 | 37746-78-4 | MFCD00000247 | 5G
Ethyl 4-bromocrotonate 75%, technical grade | Purity: 75% | Mol Wt: 193.04 | 37746-78-4 | MFCD00000247 | 5G
Medchemexpress LLC Indacaterol maleate | 753498-25-8 | MFCD20526769 | 99.6% | C28H32N2O7 | 10MG
Indacaterol maleate is the maleate salt of indacaterol, an ultra-long-acting β2-adrenergic receptor agonist. This product is supplied as an analytical reference standard for research and laboratory use and is intended for assay development, method validation, and quality control (not for human use).
- High-purity reference material (HPLC 99.62%).
- Suitable for assay development and method validation.
- Intended for research and analytical use only.
- Supplied as a stable solid for standard preparation.
- Identified by CAS 753498-25-8 for unambiguous reference.
Medchemexpress LLC Neratinib maleate | 915942-22-2 | 99.7% | 673.11 | 100 MG
Neratinib maleate is an orally available, irreversible, highly selective HER2 and EGFR inhibitor with IC50s of 59 nM and 92 nM, respectively. It is for research use only.
- Orally available
- Irreversible inhibitor
- Highly selective HER2 and EGFR inhibitor
- Inhibits proliferation of cell lines with high HER-2 levels
- Less active in cell lines expressing neither HER-2 nor EGFR
- Arrests BT474 cell cycle at G1-S phase
- Inhibits MAPK and Akt phosphorylation
- Down-regulates cyclin D1 levels
- Induces p27
Medchemexpress LLC Monostearyl maleate | 2424-62-6 | MFCD08274815 | 98.0% | 368.55 g/mol | C22H40O4 | 1 G
Monostearyl maleate (octadecyl fumarate) is a long-chain alkyl ester used as a research reagent and analytical reference. It is a hydrophobic ester typically applied in laboratory synthesis, formulation studies, and as an analytical standard. Key chemical identifiers include CAS 2424-62-6, molecular formula C22H40O4, and molecular weight 368.55 g/mol.
Apexbio Technology LLC (S)-(+)-Dimethindene maleate(Synonyms: (+)-Dimethindene maleate, Dexdimethindene maleate, (S)-Dimetindene maleate, (S)-(+)-Dimetindene maleate), 50mg, CAS: 136152-65-3.
(S)-( )-Dimethindene maleate (CAS 136152-65-3) is a small molecule antagonist exhibiting selective affinity for the muscarinic acetylcholine receptor subtype M2 while showing comparatively reduced interaction with M1 M3 and M4 subtypes Additionally it acts as an antagonist at histamine H1 receptors Due to its receptor selectivity profiles it is employed in pharmacological studies investigating autonomic regulation mechanisms cardiovascular physiology and respiratory system function
eMolecules 48145-04-6 | 2-Phenoxyethyl acrylate | Ambeed | MFCD00053696 | 192.214 | C11H12O3 | 90.000 | C=CC(=O)OCCOc1ccccc1 | 25g | 632809883
2-Phenoxyethyl acrylate | Ambeed | 48145-04-6 | MFCD00053696 | 192.214 | C11H12O3 | 90.000 | C=CC(=O)OCCOc1ccccc1 | 25g | 632809883
Medchemexpress LLC Indacaterol maleate | 753498-25-8 | 99.6% | C28H32N2O7 | 25 MG
Indacaterol maleate (QAB149) is an orally active ultra-long-acting β2 adrenergic receptor (ADRB2) agonist. It inhibits NF-κB activity in a β-arrestin2-dependent manner, preventing lung damage and improving lung function in chronic obstructive pulmonary disorder (COPD). It also shows promise in cardiovascular disease research, normalizing and reversing cardiac remodeling in a myocardial infarction rat model of heart failure.
- Inhibits NF-κB activity in a β-arrestin2-dependent manner.
- Helps prevent lung damage.
- Improves lung function in chronic obstructive pulmonary disorder (COPD).
- Used in cardiovascular disease research.
- Normalizes and reverses cardiac remodeling in myocardial infarction rat models.
Medchemexpress LLC Pirepemat fumarate | 2251806-70-7 | 98.3% | C15H17F2NO5 | 10MG
Pirepemat fumarate is the fumarate salt of pirepemat (IRL752), a cortical-preferring catecholamine- and cognition-promoting research compound investigated for reducing falls and improving cognitive and motor function in Parkinson's disease. The compound is provided as a stable fumarate salt and is used in preclinical and clinical research to modulate cortical neurotransmitter signaling.
- Fumarate salt for improved chemical stability.
- Cortical-preferring catecholamine and cognition-promoting activity.
- Investigated for reduction of falls and improvement of balance in Parkinson's disease.
- Shown to enhance cortical dopamine, acetylcholine, and norepinephrine transmission.
- Supplied in solid and DMSO solution formats for flexible dosing and formulation.
- High purity suitable for research applications.
Medchemexpress LLC Sumanirole maleate (U-95666E; PNU-95666E) | 179386-44-8 | 99.8% | C15H17N3O5 | 100 MG
Sumanirole maleate (U-95666E; PNU-95666E) is a highly selective D2 receptor full agonist with an ED50 of about 46 nM. It plays an important role in the research of Parkinson's disease and restless leg syndrome.
- Highly selective D2 receptor full agonist
- ED50 of about 46 nM
- Valuable tool compound for basic research
- Identifies neurobiological mechanisms based on dopamine D2-linked mechanism of action
Medchemexpress LLC Sumanirole maleate | 179386-44-8 | 99.8% | C15H17N3O5 | 1 ML
Sumanirole maleate is a highly selective D2 receptor full agonist with an ED50 of approximately 46 nM. It is important in the research of Parkinson's disease and restless leg syndrome. Sumanirole serves as a valuable tool compound for basic research to identify neurobiological mechanisms based on a dopamine D2-linked mechanism of action.
- Highly selective D2 receptor full agonist
- ED50 of approximately 46 nM
- Important in research of Parkinson's disease
- Important in research of restless leg syndrome
- Valuable tool compound for basic research
Selleck Chemical LLC Indacaterol Maleate S3083-5mg
Indacaterol (QAB149) is an ultra-long-acting -adrenoceptor agonist with pKi of 7 36 for 1-adrenoceptor and pKi of 5 48 for 2-adrenoceptor
Medchemexpress LLC Cinepazide Maleate | 26328-04-1 | 99.7% | C26H35N3O9 | 25 MG
Cinepazide Maleate is a piperazine derivative that acts as a weak calcium channel blocker and a potent vasodilator. It is utilized in research for cerebrovascular diseases, including ischemic stroke and brain infarct.
- Acts as a weak calcium channel blocker
- Potent vasodilator
- Used for research on cerebrovascular diseases
- Suitable for ischemic stroke and brain infarct research
- For research use only
Medchemexpress LLC Neratinib maleate | 915942-22-2 | 99.7% | 673.11 | 25 MG
Neratinib maleate is an orally available, irreversible, and highly selective inhibitor of HER2 and EGFR, intended for research use only. It inhibits the proliferation of cell lines expressing high levels of HER-2 and demonstrates anticancer activities in vivo by reducing tumor growth in a dose-dependent manner in various xenografts.
- Orally available, irreversible, highly selective HER2 and EGFR inhibitor.
- Inhibits proliferation of cell lines with high HER-2 levels.
- Arrests cell cycle at G1-S phase.
- Inhibits MAPK and Akt phosphorylation.
- Down-regulates cyclin D1 levels and induces p27.
- Shows anticancer activities against HER-2 or EGFR expressing cancer cells in vivo.
Medchemexpress LLC Omigapil maleate | 200189-97-5 | 99.8% | 391.42 | 25 MG
Omigapil maleate (CGP3466B) is an orally active GAPDH nitrosylation inhibitor that abrogates Aβ1-42-induced tau acetylation, memory impairment, and locomotor dysfunction in mice. It has potential for Alzheimer's disease research and is also an apoptosis inhibitor. Additionally, it can be used for congenital muscular dystrophy (CMD) research.
- Orally active GAPDH nitrosylation inhibitor.
- Abrogates Aβ1-42-induced tau acetylation, memory impairment, and locomotor dysfunction in mice.
- Potential for Alzheimer's disease research.
- Apoptosis inhibitor.
- Can be used for congenital muscular dystrophy (CMD) research.
- Click chemistry reagent with an alkyne group for CuAAc reactions.