Carboxylic acids and derivatives
TARGETMOL CHEMICALS INC FLUPIRTINE MALEATE 200MG
Also available in 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Flupirtine maleate (Katadolon maleate) a centrally acting non-opioid analgesia is the salt form of Flupirtine. It is an NMDA receptor antagonist and also a specific neuronal potassium channel opener. purity: 99%
Medchemexpress LLC Ciproxifan maleate | 184025-19-2 | C20H22N2O6 | 1 ML
Ciproxifan maleate is a potent, selective, orally bioavailable, and competitive antagonist of the histamine H3-receptor, with an IC50 of 9.2 nM. It shows low apparent affinity at other receptor subtypes and can be used for the research of aging disorders and Alzheimer's disease.
- Inhibits [3H]HA release from synaptosomes of rat cerebral cortex (Ki: 0.5 nM).
- Inhibits binding of [125I]iodoproxyfan with rat striatal membranes (Ki: 0.7 nM).
- Increases t-MeHA level in mouse brain (ED50: 0.14 mg/kg).
- Improves accuracy of responding in five-choice tasks in rats.
- Induces neocortical electroencephalogram activation and waking state in cats.
- Decreases H3-receptor ligand concentration in serum in mice.
- Exhibits oral bioavailability (F=62%) and maximal concentration (Cmax=420 nM) in mice.
Medchemexpress LLC U-99194 maleate (U-99194A) | 234757-41-6 | 99.2% | 50 MG
U-99194 (PNU-99194) maleate is a selective and potent dopamine D3 receptor antagonist. It inhibits the activation of D3 receptors mediated by endogenously released dopamine or exogenous D3 agonists. This compound can be used for the study of dopamine D3 receptor-mediated motor disorders, particularly kinetic tremors.
- Selective, potent dopamine D3 receptor antagonist (Ki = 160 nM).
- Inhibits D3 receptor activation.
- Abrogates IPSC-suppressive effect of D3 agonist PD 128907 in rat hippocampal slices.
- Significantly suppresses nicotine-induced tremor in mice.
- Useful for studying dopamine D3 receptor-mediated motor disorders, especially kinetic tremors.
Medchemexpress LLC (S)-timolol maleate | 26921-17-5 | MFCD00058356 | 100.0% | 432.49 | C17H28N4O7S | 10 MG
(S)-Timolol maleate is the S-enantiomer of timolol supplied as the maleate salt and provided as an analytical/research standard for pharmacological testing, method development, and quality control. It is a non-cardioselective, hydrophilic β-adrenoceptor blocker commonly used in research related to intraocular pressure and cardiovascular effects.
- Analytical standard for method development and quality control.
- S-enantiomer maleate salt with defined stereochemistry.
- High purity suitable for HPLC and reference standard use.
- Molecular weight 432.49 and formula C17H28N4O7S.
- Store sealed at 4°C, protected from light and moisture.
eMolecules 922-67-8 | Methyl propiolate | AA Blocks LLC | MFCD00008572 | 84.074 | C4H4O2 | 0.000 | COC(=O)C#C | 25g | 448665144
Methyl propiolate | AA Blocks LLC | 922-67-8 | MFCD00008572 | 84.074 | C4H4O2 | 0.000 | COC(=O)C#C | 25g | 448665144
Medchemexpress LLC Neratinib maleate | 915942-22-2 | 99.7% | 673.11 | 50 MG
Neratinib maleate (HKI-272 maleate) is an orally available, irreversible, highly selective HER2 and EGFR inhibitor. It is intended for research use only.
- Inhibits HER2 and EGFR with IC50s of 59 nM and 92 nM, respectively.
- Demonstrates antiproliferative effects in cell lines with high HER-2 levels.
- Arrests cell cycle at G1-S phase in BT474 cells.
- Inhibits MAPK and Akt phosphorylation, and induces p27.
- Exhibits anticancer activities against HER-2 or EGFR expressing cancer cells in vivo.
- Reduces tumor growth in xenograft models.
(C)OCCCCI | 250mg | 600839556](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502430575.PNG-250.jpg)
eMolecules 92511-12-1 | tert-Butyl(4-iodobutoxy)diMethylsilane | Ambeed | MFCD01863695 | 314.282 | C10H23IOSi | 95.000 | CC(C)(C)[Si](C)(C)OCCCCI | 250mg | 600839556
tert-Butyl(4-iodobutoxy)diMethylsilane | Ambeed | 92511-12-1 | MFCD01863695 | 314.282 | C10H23IOSi | 95.000 | CC(C)(C)[Si](C)(C)OCCCCI | 250mg | 600839556
Apexbio Technology LLC Menadiol Diacetate 573-20-6 1g
Menadiol Diacetate (CAS 573-20-6) is a synthetic derivative of vitamin K investigated for its regulatory effects on cellular signaling pathways and enzyme activities In experimental studies Menadiol Diacetate has been shown to induce S phase arrest in the cell cycle leading to apoptotic cell death This compound is utilized in research focused on cancer and related diseases providing a tool for exploring mechanisms of cell proliferation and apoptosis in vitro
Medchemexpress LLC PTP1B-IN-3 Diammonium | 2026852-51-7 | C20H28N4O10P2 | 1 ML
PTP1B-IN-3 Diammonium is a potent and selective inhibitor of PTP1B, demonstrating an IC50 of 0.49 nM. It exhibits good selectivity against TCPTP with an IC50 of 330 nM and SHP-2 with an IC50 of 13 μM. This compound has been shown to promote insulin signaling and effectively lower glucose levels in ob/ob mice, making it a valuable tool for research into type 2 diabetes and obesity.
- Potent and selective PTP1B inhibitor
- Shows good selectivity against TCPTP and SHP-2
- Promotes insulin signaling
- Lowers glucose levels in ob/ob mice
- Useful for research of type 2 diabetes
- Useful for research of obesity
Medchemexpress LLC NB-598 Maleate | 155294-62-5 | 99.4% | 565.74 | 2 MG
NB-598 Maleate is a potent and competitive inhibitor of squalene epoxidase (SE) that suppresses triglyceride biosynthesis through the farnesol pathway. It also functions as a click chemistry reagent, containing an Alkyne group.
- Potent and competitive inhibitor of squalene epoxidase (SE)
- Suppresses triglyceride biosynthesis through the farnesol pathway
- Click chemistry reagent containing an alkyne group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups
eMolecules 103-41-3 | Benzyl cinnamate | Oakwood Chemical | MFCD00004789 | 238.286 | C16H14O2 | 99.000 | O=C(OCc1ccccc1)\C=C\c1ccccc1 | 25g | 537707346
Benzyl cinnamate | Oakwood Chemical | 103-41-3 | MFCD00004789 | 238.286 | C16H14O2 | 99.000 | O=C(OCc1ccccc1)\C=C\c1ccccc1 | 25g | 537707346
Medchemexpress LLC Ciproxifan (maleate) | 184025-19-2 | MFCD06411563 | 99.7% | 386.40 g/mol | C20H22N2O6 | 10 MG
Ciproxifan maleate is a potent, selective, orally bioavailable competitive antagonist of the histamine H3 receptor supplied as a white to off-white powder for research use. It is used as an analytical standard and research reagent in neuroscience and aging-disease studies, with reported nanomolar potency.
- Potent H3 receptor antagonist (IC50 ≈ 9.2 nM)
- High purity (≈ 99.7%)
- Provided as a powdered maleate salt for stability and handling
- Suitable for neuroscience and Alzheimer's disease research
- Available in small pack sizes for analytical and screening use
- Includes CAS number 184025-19-2 and molecular weight 386.40 g/mol
TARGETMOL CHEMICALS INC WAY-100635 maleate 25MG
Also available in 1 mL, 2 mg, 5 mg, 10 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. WAY-100635 Maleate is a specific and effective 5-HT receptor antagonist (IC50=0.95 nM). Purity 100%
Medchemexpress LLC Ethynodiol diacetate | 297-76-7 | 99.9% | 1 ML
Ethynodiol diacetate is a click chemistry reagent that contains an Alkyne group. It can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Features and benefits:
- Contains an alkyne group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Reacts with molecules containing azide groups
Cayman Chemical FluoresceIn dIacetate 5g
A cell-permeable fluorogenic cell viability probe; cleaved by intracellular esterases to produce fluorescein which displays excitation/emission maxima of 490/520 nm, respectively