Fluorobenzenes

Organic compounds considered aryl halides that consist of a phenyl group with a fluorine atom substitution in the following structure: C₆H₅F.

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1,951 – 1,965 of 4,400 results

1,951

Medchemexpress LLC Dxd 5Mg | HY-13631D-5MG

Dxd 5Mg

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1,952

eMolecules 60811-18-9 | 4-Bromo-1-chloro-2-fluorobenzene | Ambeed | MFCD00042519 | 209.44 | C6H3BrClF | 98 | Fc1cc(Br)ccc1Cl | 10g | 525019385

4-Bromo-1-chloro-2-fluorobenzene | Ambeed | 60811-18-9 | MFCD00042519 | 209.440 | C6H3BrClF | 98.000 | Fc1cc(Br)ccc1Cl | 10g | 525019385

Pricing & Availability

1,953

eMolecules 460-00-4 | 1-Bromo-4-fluorobenzene | Ambeed | MFCD00000342 | 175 | C6H4BrF | 95 | Fc1ccc(Br)cc1 | 10g | 518523234

Ambeed | 3-Bromo-5-chloropyrazolo[15-a]pyrimidine | 1g | 525199200 | A373429 | 960613-96-1 | MFCD11520857 | 232.470 | C6H3BrClN3

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1,954

Medchemexpress LLC Tolinapant | 1799328-86-1 | 99.81% | 539.68 | 1 ML

Tolinapant (ASTX660) is an orally bioavailable dual antagonist of cellular inhibitor of apoptosis protein (cIAP) and X-linked inhibitor of apoptosis protein (XIAP).

Orally bioavailable dual antagonist of cellular inhibitor of apoptosis protein (cIAP) and X-linked inhibitor of apoptosis protein (XIAP)
Being investigated in a single-agent Phase 1/2 clinical trial in patients with advanced solid tumors and lymphomas
Demonstrates antiproliferative activity against human MDA-MB-231 cells with an IC50 of 1.8 nM
Shows efficacy in HCC1806 xenografts in mice by causing moderate tumor growth inhibition
Available with a purity of 99.81%

Pricing & Availability

1,955

Medchemexpress LLC NVS-SM2 | 1562333-92-9 | 99.15% | 406.52 | 10 MG

NVS-SM2 is a potent, orally active, and brain-penetrant SMN2 splicing enhancer. It enhances U1-pre-mRNA association, promotes exon 7 inclusion, and restores normal survival motor neuron (SMN) protein expression. This compound is suitable for spinal muscular atrophy (SMA) research.

Potent, orally active, and brain-penetrant SMN2 splicing enhancer
Enhances U1-pre-mRNA association
Promotes exon 7 inclusion
Restores normal survival motor neuron (SMN) protein expression
Suitable for spinal muscular atrophy (SMA) research

Pricing & Availability

1,956

Medchemexpress LLC NVS-SM2 | 1562333-92-9 | 99.15% | 406.52 | 5 MG

NVS-SM2 | 1562333-92-9 | 99.15% | 406.52 | 5 MG

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1,957

Medchemexpress LLC Tas-119 | 1453099-83-6 | 98.0% | 506.36 | 50 MG

TAS-119 is a potent, selective, and orally active Aurora A inhibitor with an IC50 of 1.0 nM. It demonstrates high selectivity for Aurora A over other protein kinases, including Aurora B (IC50 of 95 nM). This compound exhibits potent antitumor activities.

Enhances the antiproliferative effect of Paclitaxel in various human cancer cell lines, including Paclitaxel-resistant cells.
Increases cell growth inhibition by taxanes (Paclitaxel, Docetaxel, and Cabazitaxel) in HeLa cells.
Induces mitotic accumulation predominantly in tumor cells compared to normal diploid fibroblasts.
Induces phosphorylated histone H3 (pHH3) in nude rats with HeLa-luc xenografts.

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1,958

Medchemexpress LLC (R)-GSK-3685032 | 2170140-50-6 | 99.0% | 420.53 | 50 MG

(R)-GSK-3685032 is the R-enantiomer of GSK-3685032, a first-in-class, non-time-dependent, noncovalently, reversible DNMT1-selective inhibitor with an IC50 of 0.036 μM. It is designed to induce robust loss of DNA methylation, transcriptional activation, and inhibition of cancer cell growth.

Selective DNMT1 inhibitor
Target: DNMT1
Induces loss of DNA methylation and transcriptional activation
Inhibits cancer cell growth
Solid storage: 4°C, sealed, away from moisture and light
Solvent storage: -80°C for 6 months; -20°C for 1 month (sealed, away from moisture and light)

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1,959

Medchemexpress LLC WEE1-IN-3 | 2272976-28-8 | 98.6% | 497.59 | 100 MG

WEE1-IN-3 is a potent inhibitor of Wee1 kinase with an IC50 of less than 10 nM. It demonstrates anticancer activities. WEE1 kinase is crucial for the G2-M cell-cycle checkpoint, which is involved in DNA repair before mitotic entry. While normal cells repair damaged DNA during G1 arrest, cancer cells often have a deficient G1-S checkpoint and rely on a functional G2-M checkpoint for DNA repair. WEE1 is found to be overexpressed in various cancer types. WEE1-IN-3 inhibits cancer cell growth with IC50 values of 100-1000 nM for SW480 cells and less than 100 nM for H23 cells.

Potent Wee1 kinase inhibitor with an IC50 of <10 nM.
Exhibits anticancer activities.
Inhibits cancer cell growth in SW480 and H23 cells.
Available as solid or solution in DMSO.

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1,960

Medchemexpress LLC (R)-GSK-3685032 | 2170140-50-6 | >99.0% | 420.53 | 100 MG

(R)-GSK-3685032 is the R-enantiomer of GSK-3685032. It is a first-in-class, non-time-dependent, noncovalently, and reversible DNMT1-selective inhibitor, with an IC50 of 0.036 μM. It induces robust loss of DNA methylation, transcriptional activation, and inhibition of cancer cell growth.

Reversible DNMT1-selective inhibitor
Induces loss of DNA methylation
Promotes transcriptional activation
Inhibits cancer cell growth

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1,961

Medchemexpress LLC AHR antagonist 5 | 2247953-39-3 | 98.1% | 550.89 | 50 MG

AHR antagonist 5 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist, extracted from patent WO2018195397, example 39, with an IC50 of < 0.5 μΜ. It significantly inhibits tumor growth when combined with the checkpoint inhibitor anti-PD-1.

Potent and orally active aryl hydrocarbon receptor (AHR) antagonist
Inhibits tumor growth when combined with checkpoint inhibitor anti-PD-1

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1,962

Medchemexpress LLC HPK1-IN-3 | 2739844-34-7 | 98.61% | 490.45 | 100 MG

HPK1-IN-3 is a potent and selective ATP-competitive hematopoietic progenitor kinase 1 (HPK1; MAP4K1) inhibitor with an IC50 of 0.25 nM. It has IL-2 cellular potency with an EC50 of 108 nM in human peripheral blood mononuclear cells (PBMCs).

Potent and selective ATP-competitive HPK1 (MAP4K1) inhibitor with an IC50 of 0.25 nM.
Exhibits IL-2 cellular potency with an EC50 of 108 nM in human peripheral blood mononuclear cells (PBMCs).
Can elevate proinflammatory cytokines IL-6 and TNF-α in human monocyte-derived dendritic cells.

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1,963

Medchemexpress LLC HPK1-IN-4 | 2739844-28-9 | 434.49 | 100 MG

HPK1-IN-4 is an inhibitor of HPK1 (MAPK41), designed as a preclinical immunoresearch tool compound. It exhibits potent activity against HPK1 with a low IC50 value, making it suitable for various research applications targeting the MAPK/ERK pathway. It can be formulated for both in vitro and in vivo studies.

Inhibits HPK1 (MAPK41) with high potency
Preclinical immunoresearch tool compound
Targeted to the MAPK/ERK pathway
Suitable for in vitro and in vivo applications
Solubility data available for various solvents and formulations

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1,964

Medchemexpress LLC Fosaprepitant dimeglumine | 265121-04-8 | 98.2% | C₃₇H₅₆F₇N₆O₁₆P | 100 MG

Fosaprepitant dimeglumine (MK-0517) is a proagent of Aprepitant and functions as a neurokinin-1 receptor antagonist. It is developed for the prevention of chemotherapy-induced nausea and vomiting (CINV). For research use only, this product is not sold to patients.

Proagent of Aprepitant.
Neurokinin-1 receptor antagonist.
Developed for preventing chemotherapy-induced nausea and vomiting (CINV).
Increases the antinociceptive effect in rats when administered intraperitoneally.

Pricing & Availability

1,965

Medchemexpress LLC (Rac)-lunresertib | 2719749-28-5 | 99.7% | C18H20N4O2 | 50 MG

(Rac)-lunresertib (compound 181) is a potent membrane-associated tyrosine and threonine-specific cdc2-inhibitory kinase (Myt1) (Gene name PKMYT1) inhibitor with an IC50 of <10 nM. It demonstrates anticancer effects.

Potent Myt1 inhibitor
Exhibits anticancer effects
Soluble in DMSO (100 mg/mL)

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Fluorobenzenes

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Medchemexpress LLC Dxd 5Mg | HY-13631D-5MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Tolinapant | 1799328-86-1 | 99.81% | 539.68 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC NVS-SM2 | 1562333-92-9 | 99.15% | 406.52 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC NVS-SM2 | 1562333-92-9 | 99.15% | 406.52 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Tas-119 | 1453099-83-6 | 98.0% | 506.36 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC (R)-GSK-3685032 | 2170140-50-6 | 99.0% | 420.53 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC WEE1-IN-3 | 2272976-28-8 | 98.6% | 497.59 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC (R)-GSK-3685032 | 2170140-50-6 | >99.0% | 420.53 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC AHR antagonist 5 | 2247953-39-3 | 98.1% | 550.89 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HPK1-IN-3 | 2739844-34-7 | 98.61% | 490.45 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HPK1-IN-4 | 2739844-28-9 | 434.49 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Fosaprepitant dimeglumine | 265121-04-8 | 98.2% | C₃₇H₅₆F₇N₆O₁₆P | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC (Rac)-lunresertib | 2719749-28-5 | 99.7% | C18H20N4O2 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More