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Filtered Search Results
Medchemexpress LLC (S)-5-fluoro-2-(1-(4-fluorophenyl)ethylamino)-6-(5-methyl-1H-pyrazol-3-ylamino)nicotinonitrile | 905586-69-8 | MFCD16621127 | >98.0% | 354.36 g/mol | C18H16F2N6 | 100 MG
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AZ960 is a small-molecule, ATP-competitive inhibitor of Janus kinase 2 (JAK2) used as a research reagent to study JAK/STAT signaling and JAK2-driven cellular models. It has high potency and has been used in preclinical studies to induce growth arrest and apoptosis in JAK2-dependent cells.
- Potent JAK2 inhibition (Ki ≈ 0.45 nM).
- Selective profile with reduced activity against JAK1, JAK3, and TYK2.
- High purity (>98% by HPLC) suitable for biochemical and cellular assays.
- Chemical formula C18H16F2N6 and molecular weight 354.36 g/mol.
- Solid powder form, soluble in DMSO for stock solutions.
- Used for JAK/STAT pathway studies and preclinical cell-based assays.
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Medchemexpress LLC PD-L1-IN-1 | 2767424-13-3 | 377.44 | 50 MG
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PD-L1-IN-1 is a potent PD-L1 inhibitor with an IC50 of 115 nM. It strongly binds to the PD-L1 protein, enhancing the antitumor immune activity of peripheral blood mononuclear cells in co-culture with PD-L1 expressing cancer cells. It increases IFN-γ release and induces apoptosis.
- Potent PD-L1 inhibitor.
- Enhances antitumor immune activity.
- Induces apoptosis.
- Exhibits low cytotoxicity in healthy cells.
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Medchemexpress LLC HY-12993A 5mg Medchemexpress, RSV604 (racemate) CAS:676128-62-4 Purity:>98%
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Medchemexpress, HY-12993A 5mg RSV604 (racemate) CAS:676128-62-4 RSV604 racemate is a racemic mixture, shows less potency against strains of respiratory syncytial virus (RSV) than the S-isomer. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Selleck Chemical LLC 3 -Fluoro-3 -deoxythymidine
3 -Fluoro-3 -deoxythymidine (Alovudine CL 184824 FddThd FLT MIV-310) is a potent inhibitor of polymerase and reverse transcriptase that can be used in the treatment of HIV infection 3 -Fluoro-3 -deoxythymidine (Alovudine) is also a marker of DNA synthesis that can be used as an early response biomarker in the chemotherapy of pancreatic cancer
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Medchemexpress LLC HY-114339 5mg Medchemexpress, CDK4/6-IN-2 CAS:1800506-48-2 Purity:>98%
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Medchemexpress, HY-114339 5mg CDK4/6-IN-2 CAS:1800506-48-2 CDK4/6-IN-2 is a potent CDK4 and CDK6 inhibitor extracted from patent US20180000819A1, Compound 1, has IC 50 s of 2.7 and 16 nM for CDK4 and CDK6, respectively [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC 3a-bis-(4-fluorophenyl) methoxytropane (hydrochloride) | 202646-03-5 | 100.0% | 379.87 | C21H24ClF2NO | 25 MG
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AHN 1-055 hydrochloride is the hydrochloride salt of 3α-bis-(4-fluorophenyl) methoxytropane, a research compound that inhibits dopamine uptake with a reported IC50 of about 71 nM. Supplied as a high-purity solid, it is intended for pharmacological and neurochemical studies of dopamine transporter activity in vitro and in vivo.
- High-purity solid suitable for research use.
- Potent dopamine transporter inhibitor (IC50 ≈71 nM).
- Appropriate for in vitro and in vivo pharmacology studies.
- Available in small, accurately weighed quantities for dose-ranging.
- Store sealed at 4°C; in solution store at -80°C for long-term preservation.
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eMolecules 1065609-00-8 | Medchem Express | AR453588 | 5mg | 599150678 | HY-133127 | 519.64 | C25H25N7O2S2
ChemScene | 3-Amino-124-triazine | 5g | 789369304 | CS-W004843 | 1120-99-6 | 96.093 | C3H4N4
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Medchemexpress LLC (R)-UT-155 | 2031161-54-1 | 98.1% | 405.35 | 10 MG
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(R)-UT-155 (compound 11) is a selective androgen receptor degrader (SARD) ligand. It is less active than its S-isomer. This compound is used in various research applications, particularly in cancer and urogenital disease studies.
- High purity: 98.1%
- Molecular weight: 405.35
- Solid appearance, white to off-white color
- Soluble in DMSO at 100 mg/mL
- Effective antagonist activity at human androgen receptor in HEK293 cells (IC50: 0.598 μM)
- Stable storage conditions for powder and in solvent
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![Medchemexpress LLC N-[(1R)-1-(3-cyclopentyloxyphenyl)ethyl]-3-[(2,4-dioxopyrimidin-1-yl)methoxy]propane-1-sulfonamide | 1198221-21-4 | 99.8% | 451.5 g/mol | C21H29N3O6S | 1MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000238280.png-250.jpg)
Medchemexpress LLC N-[(1R)-1-(3-cyclopentyloxyphenyl)ethyl]-3-[(2,4-dioxopyrimidin-1-yl)methoxy]propane-1-sulfonamide | 1198221-21-4 | 99.8% | 451.5 g/mol | C21H29N3O6S | 1MG
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TAS-114 is an orally active small-molecule inhibitor that dual-targets deoxyuridine triphosphatase (dUTPase) and dihydropyrimidine dehydrogenase (DPD). It has been investigated as an adjunct to fluoropyrimidine chemotherapy to enhance efficacy by modulating nucleotide metabolism and reducing catabolism of 5-fluorouracil (CAS 1198221-21-4).
- Dual inhibition of dUTPase and DPD enhances fluoropyrimidine efficacy.
- Oral bioavailability suitable for systemic administration.
- Defined molecular formula and molecular weight support reproducible characterization.
- High reported chemical purity enables reliable experimental results.
- Appropriate for preclinical research on combination chemotherapy strategies.
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Medchemexpress LLC HY-13016 50mg Medchemexpress, Cabozantinib CAS:849217-68-1 Purity:>98%
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Medchemexpress, HY-13016 50mg Cabozantinib CAS:849217-68-1 Cabozantinib is a potent multiple receptor tyrosine kinases (RTKs) inhibitor that inhibits VEGFR2, c-Met, Kit, Axl and Flt3 with IC50s of 0.035, 1.3, 4.6, 7 and 11.3 nM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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![eMolecules 90897-92-0 | 3,4-Difluorophenylmagnesium bromide | Rieke Metals | MFCD00672004 | 217.296 | C6H3BrF2Mg | [Br-].Fc1ccc([Mg+])cc1F | 100ml | 118910412](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC1645888.jpg-250.jpg)
eMolecules 90897-92-0 | 3,4-Difluorophenylmagnesium bromide | Rieke Metals | MFCD00672004 | 217.296 | C6H3BrF2Mg | [Br-].Fc1ccc([Mg+])cc1F | 100ml | 118910412
3,4-Difluorophenylmagnesium bromide | Rieke Metals | 90897-92-0 | MFCD00672004 | 217.296 | C6H3BrF2Mg | [Br-].Fc1ccc([Mg+])cc1F | 100ml | 118910412
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Medchemexpress LLC HY-100459 1mg Medchemexpress, GSK3179106 CAS:1627856-64-7 Purity:>98%
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Medchemexpress, HY-100459 1mg GSK3179106 CAS:1627856-64-7 GSK3179106 is a potent and selective RET kinase inhibitor with an IC 50 of 0.4 nM [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 621-71-6 | Tricaprin | Combi-Blocks | MFCD00036239 | 554.853 | C33H62O6 | 98.000 | CCCCCCCCCC(=O)OCC(COC(=O)CCCCCCCCC)OC(=O)CCCCCCCCC | 25g | 482934266
Tricaprin | Combi-Blocks | 621-71-6 | MFCD00036239 | 554.853 | C33H62O6 | 98.000 | CCCCCCCCCC(=O)OCC(COC(=O)CCCCCCCCC)OC(=O)CCCCCCCCC | 25g | 482934266
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Medchemexpress LLC HY-101561 5mg Medchemexpress, Avapritinib CAS:1703793-34-3 Purity:>98%
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Medchemexpress, HY-101561 5mg Avapritinib CAS:1703793-34-3 Avapritinib (BLU-285) is a highly potent, selective, and orally bioavailable KIT and PDGFRA activation loop mutant kinases inhibitor with IC 50 s of 0.27 and 0.24 nM for KIT D816V and PDGFRA D842V, respectively. Avapritinib (BLU-285) binds the active conformation of the kinase and shows antitumor activity. Avapritinib (BLU-285) attenuates the transport function of both ABCB1 and ABCG2 [1] [2] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 1144477-35-9 | Medchem Express | TM-N1324 | 5mg | 446259378 | HY-108699 | 397.8 | C18H13ClFN7O
Ambeed | 6-Chloro-3-fluoropicolinonitrile | 100mg | 596329814 | A273736 | 1207609-52-6 | MFCD18250470 | 156.540 | C6H2ClFN2
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