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Filtered Search Results
Medchemexpress LLC HY-18957 5mg Medchemexpress, Lifirafenib CAS:1446090-79-4 Purity:>98%
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Medchemexpress, HY-18957 5mg Lifirafenib CAS:1446090-79-4 Lifirafenib (BGB-283) is a novel and potent Raf Kinase and EGFR inhibitor with IC50 values of 23 and 29 nM for recombinant BRafV600E and EGFR, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-19694 5mg Medchemexpress, BRD7552 CAS:1137359-47-7 Purity:>98%
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Medchemexpress, HY-19694 5mg BRD7552 CAS:1137359-47-7 BRD7552, a potent PDX1 transcription factor inducer, upregulates PDX1 expression in both primary human islets and ductal cells, and induces epigenetic changes in the PDX1 promoter consistent with transcriptional activation. BRD7552 increases insulin expression. PDX1 is a key transcription factor involved in pancreas development and β cell function. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-114286A 5mg Medchemexpress, PXS-5153A (monohydrochloride) CAS: Purity:>98%
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Medchemexpress, HY-114286A 5mg PXS-5153A (monoHCl) CAS: PXS-5153A monohydrochloride is a potent, selective, orally active and fast-acting lysyl oxidase like 2/3 enzymatic (LOXL2/LOXL3) inhibitor, with an IC50 of <40 nM for LOXL2 across all mammalian species and an IC50 of 63 nM for human LOXL3. PXS-5153A monohydrochloride could reduce crosslinks and ameliorates fibrosis. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-100729 5mg Medchemexpress, GSK9311 CAS:1923851-49-3 Purity:>98%
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Medchemexpress, HY-100729 5mg GSK9311 CAS:1923851-49-3 GSK9311 is a potent inhibitor of the BRPF bromodomain with pIC 50 values of 6.0 and 4.3 for BRPF1 and BRPF2, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-103083 5mg Medchemexpress, GPR40 agonist 4 CAS:2102196-57-4 Purity:>98%
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Medchemexpress, HY-103083 5mg GPR40 agonist 4 CAS:2102196-57-4 GPR40 agonist 4 is a potent free fatty acid receptor 1 (FFA1/ GPR40) agonist with a pEC50 of 7.54. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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![eMolecules 1044870-39-4 | RVX-208 | Broadpharm370.405 | C20H22N2O5 | 0.000 | COc1cc(OC)c2c(c1)[nH]c(nc2=O)-c1cc(C)c(OCCO)c(C)c1 | 50mg | 573896523](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502203142.JPG-250.jpg)
eMolecules 1044870-39-4 | RVX-208 | Broadpharm370.405 | C20H22N2O5 | 0.000 | COc1cc(OC)c2c(c1)[nH]c(nc2=O)-c1cc(C)c(OCCO)c(C)c1 | 50mg | 573896523
RVX-208 | Broadpharm | 1044870-39-4370.405 | C20H22N2O5 | 0.000 | COc1cc(OC)c2c(c1)[nH]c(nc2=O)-c1cc(C)c(OCCO)c(C)c1 | 50mg | 573896523
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eMolecules 1691249-44-1 | Medchem Express | (R)-Zanubrutinib | 5mg | 446256899 | HY-101474B | 471.561 | C27H29N5O3
Ambeed | 1234-Tetrahydroquinolin-4-ol | 100mg | 525148164 | A241958 | 24206-39-1 | MFCD00956625 | 149.193 | C9H11NO
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Medchemexpress LLC PROTAC KRAS G12C degrader-1 | 2984236-79-3 | 99.2% | C50H54ClFN8O6 | 10MG
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PROTAC KRAS G12C degrader-1 is a cereblon-recruiting PROTAC that induces ubiquitin-proteasome degradation of KRAS G12C mutant proteins in cellular assays. It promotes CRBN-KRASG12C ternary complex formation and is used to evaluate degradation potency and downstream signaling in reporter and cancer cell lines.
- Cereblon-based recruitment mechanism for targeted degradation.
- Effective degradation of GFP-KRASG12C in reporter cells.
- High purity suitable for biochemical and cellular experiments.
- Stable as a powder under recommended cold storage conditions.
- Available in multiple small-scale quantities for research applications.
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Medchemexpress LLC Bragsin2 | 342795-08-8 | 99.9% | 289.16 | 10 MM * 1 ML
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Bragsin2 is a potent, selective, and noncompetitive nucleotide exchange factor BRAG2 inhibitor, with an IC50 of 3 μM. It functions by binding at the interface between the PH domain of BRAG2 and the lipid bilayer, which prevents BRAG2 from activating lipidated Arf GTPase. Bragsin2 has been observed to affect breast cancer stem cells.
- Potent, selective, and noncompetitive BRAG2 inhibitor.
- IC50 of 3 μM against BRAG2.
- Inhibits Arf GTPase activation in HeLa cells.
- Inhibits the growth of SUM149 and S68 cells.
- Affects breast cancer stem cells.
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Medchemexpress LLC HY-117771A 10mg Medchemexpress, DO34 analog CAS:2098969-71-0 Purity:>98%
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Medchemexpress, HY-117771A 10mg DO34 analog CAS:2098969-71-0 DO34 analog is a triazole DAGL(α) inhibitor extracted from patent WO2017096315 A1, compound 100. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-112613 10mg Medchemexpress, UCB9608 CAS:1616413-96-7 Purity:>98%
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Medchemexpress, HY-112613 10mg UCB9608 CAS:1616413-96-7 UCB9608 is a potent, selective and orally active PI4KIIIβ inhibitor, with an IC50 of 11 nM, selective over PI3KC2 α, β, and γ lipid kinases. UCB9608 improves metabolic stability and exhibits excellent pharmacokinetic profile, acts as a potent immunosuppressive agent. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Oxomemazine | 3689-50-7 | MFCD00868197 | 99.2% | C18H22N2O2S | 10MG
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Oxomemazine is a phenothiazine-based histamine H1-receptor blocker with anticholinergic activity, supplied for research use. Common applications include studies of cough, antihistaminic effects, and muscarinic receptor modulation. Chemical identifiers: CAS 3689-50-7; formula C18H22N2O2S; molecular weight 330.44 g·mol⁻¹. Certificate of analysis reports purity ~99.18% (LCMS).
- Phenothiazine-based H1-receptor blocker suitable for pharmacology research.
- Anticholinergic properties useful for muscarinic receptor studies.
- High purity suitable for analytical and assay applications.
- Well-characterized chemical identifiers for database cross-reference.
- Provided in small quantities appropriate for method development and screening.
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![eMolecules 1024598-06-8 | 11-Phenyl-11,12-dihydroindolo[2,3-a]carbazole | MFCD22581305 | 1g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502132777.JPG-250.jpg)
eMolecules 1024598-06-8 | 11-Phenyl-11,12-dihydroindolo[2,3-a]carbazole | MFCD22581305 | 1g
Medchem Express | Purfalcamine | 5mg | 536983919 | HY-117015 | 1038620-68-6 | 528.636 | C29H33FN8O
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Medchemexpress LLC Nvp-tnks656 | 1419949-20-4 | MFCD28167762 | >98.0% | 494.58 g/mol | C27H34N4O5 | 5 MG
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NVP-TNKS656 is a potent, selective, and orally active inhibitor of tankyrase 2 (TNKS2) with a reported IC50 of 6 nM and >300-fold selectivity versus PARP1 and PARP2. It is used as a research tool to study TNKS-mediated regulation of Wnt signaling and related cellular pathways, and is supplied in small research-scale quantities suitable for biochemical and cell-based assays.
- Potent TNKS2 inhibition (IC50 ≈ 6 nM).
- High selectivity versus PARP1 and PARP2 (>300-fold).
- Orally active profile for in vivo study applications.
- Appropriate for biochemical and cell-based assays.
- Available in small-mass formats for research use.
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Medchemexpress LLC HY-10408 2mg Medchemexpress, Ki20227 CAS:623142-96-1 Purity:>98%
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Medchemexpress, HY-10408 2mg Ki20227 CAS:623142-96-1 Ki20227 is an orally active and highly selective c-Fms tyrosine kinase (CSF1R) inhibitor with IC50s of 2 nM, 12 nM, 451 and 217 nM for CSF1R, VEGFR2 (vascular endothelial growth factor receptor-2), c-Kit (stem cell factor receptor) and PDGFRβ (platelet-derived growth factor receptor β). Ki20227 suppresses osteoclast differentiation and osteolytic bone destruction. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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