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Filtered Search Results
eMolecules 122-99-6 | 2-Phenoxyethanol | Combi-Blocks | MFCD00002857 | 138.166 | C8H10O2 | 94.000 | OCCOc1ccccc1 | 25g | 342866165
2-Phenoxyethanol | Combi-Blocks | 122-99-6 | MFCD00002857 | 138.166 | C8H10O2 | 94.000 | OCCOc1ccccc1 | 25g | 342866165
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Medchemexpress LLC HY-101069 5mg Medchemexpress, Y-26763 CAS:127408-31-5 Purity:>98%
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Medchemexpress, HY-101069 5mg Y-26763 CAS:127408-31-5 Y-26763 is a K+ channel opener and active metabolite of Y-27152. Y-26763 is an ATP-sensitive K+ (KATP) channel activator. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC 5-methyl-7-methoxyisoflavone | 82517-12-2 | MFCD03093036 | 99.1% | 266.29 | C17H14O3 | 10 MG
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5-methyl-7-methoxyisoflavone is a non-steroidal isoflavone used in research for its aromatase inhibitory and antioxidant properties; it has reported remyelinating activity and NF-κB inhibitory effects and is supplied in solid and DMSO solution formats for biochemical and cellular studies.
- isoflavone scaffold with aromatase inhibitory activity.
- Orally active antioxidant with reported remyelinating properties.
- Shown to inhibit NF-κB signaling pathways.
- High listed purity (approximately 99.1%).
- Available as solid (10 mg-500 mg) and 10 mM DMSO solution formats for experimental flexibility.
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Medchemexpress LLC Mps1-IN-3 hydrochloride | 2989453-29-2 | 98.0% | 574.09 g/mol | C26H32ClN7O4S | 50MG
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Mps1-IN-3 hydrochloride is a potent, selective Mps1 (TTK) kinase inhibitor (IC50 = 50 nM) supplied as a hydrochloride salt for research use. The compound is provided as a solid with high purity and suitable solubility in DMSO for in vitro and in vivo studies.
- Molecular formula: C26H32ClN7O4S.
- Molecular weight: 574.09 g/mol.
- Purity: 98.0%.
- Appearance: Light yellow to green yellow solid.
- Solubility: DMSO ≥ 20 mg/mL.
- Storage: Store sealed at -20°C; in solution, -80°C up to 6 months or -20°C up to 1 month.
- Applications: Suitable for cellular assays and xenograft studies, including sensitization experiments.
- Packaging: Available in multiple milligram-scale quantities.
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Medchemexpress LLC (S)-UFR2709 hydrochloride | 2934318-93-9 | 98.1% | 255.74 | 50 MG
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(S)-UFR2709 hydrochloride is a competitive nAChR antagonist that shows higher affinity for α4β2 nAChRs than for α7 nAChRs. It has been observed to decrease anxiety and reduce ethanol consumption and preference in alcohol-preferring rats. It acts as an anxiolytic agent and can be used for the study of nicotine addiction.
- Competitive nAChR antagonist with higher affinity for α4β2 nAChRs than α7 nAChRs
- Decreases anxiety
- Reduces ethanol consumption and ethanol preference in alcohol-preferring rats
- Acts as an anxiolytic agent
- Can be used for the study of nicotine addiction
- Inhibits nicotine reward
- Decreases nicotine-evoked mRNA expression of α4 nACh receptor subunit in the brain of adult zebrafish
- Does not affect the weight or locomotor activity of rats at effective doses for reducing alcohol consumption
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Medchemexpress LLC Galanthamine N-Oxide | 134332-50-6 | 1 MG
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Galanthamine N-Oxide is an alkaloid derived from the bulbs of *Zephyranthes concolor*. This compound acts as an inhibitor of electric eel acetylcholinesterase (AChE) and is recognized for its role in inhibiting substrate accommodation within the active site of *Torpedo californica* AChE (TcAChE), human AChE (hAChE), and human BChE (hBChE) enzymes. It is intended for research use only.
- Derived from *Zephyranthes concolor* bulbs
- Inhibits electric eel acetylcholinesterase (AChE)
- Prominent inhibitor of substrate accommodation in AChE and BChE enzymes
- Target: Cholinesterase (ChE)
- Pathway: Neuronal Signaling
- Appears as a white to off-white solid
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Medchemexpress LLC Phenoxybenzamine hydrochloride | 63-92-3 | MFCD00055152 | 99.5% | 100 MG
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Phenoxybenzamine hydrochloride (Standard) serves as the analytical standard for Phenoxybenzamine hydrochloride, intended for research and analytical applications. It is an irreversible, nonselective, and orally active α-adrenoceptor antagonist, frequently employed in hypertension research, particularly for cases caused by pheochromocytoma. This compound also exhibits antitumor activity.
- Analytical standard for phenoxybenzamine hydrochloride
- Intended for research and analytical applications
- Nonselective α-adrenoceptor antagonist
- Irreversible α-adrenoceptor antagonist
- Orally active α-adrenoceptor antagonist
- Used in research for hypertension caused by pheochromocytoma
- Shows antitumor activity
- Commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS
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Medchemexpress LLC Ly2365109 hydrochloride | 1779796-27-8 | 98.7% | 421.91 | C22H28ClNO5 | 25 MG
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LY2365109 hydrochloride is a potent, selective glycine transporter 1 (GlyT1) inhibitor that increases glycine levels in cerebrospinal fluid and raises seizure thresholds in preclinical models. It is provided as a solid research reagent with characterized purity and stability profiles.
- Potent and selective GlyT1 inhibitor, IC50 15.8 nM for glycine uptake.
- Elevates CSF glycine levels in preclinical studies.
- Shown to increase seizure thresholds in animal models.
- High purity suitable for research use (98.69%).
- White to off-white solid, molecular weight 421.91, formula C22H28ClNO5.
- Soluble in DMSO (≥31 mg/mL) and insoluble in water (<0.1 mg/mL).
- Recommended storage sealed at 4°C; in solvent store at -80°C for long term.
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Medchemexpress LLC HY-13968 10mg Medchemexpress, JW 55 CAS:664993-53-7 Purity:>98%
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Medchemexpress, HY-13968 10mg JW 55 CAS:664993-53-7 JW 55 is a potent and selective β-catenin signaling pathway inhibitor, which functions via inhibition of the PARP domain of tankyrase 1 and tankyrase 2 (TNKS1/2). JW 55 decreases auto-PARsylation of TNKS1/2 in vitro with IC50s of 1.9 μM and 830 nM respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC AMG 579 | 1227067-61-9 | 99.0% | 50 MG
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AMG 579 is a potent, selective, and efficacious inhibitor of phosphodiesterase 10A (PDE10A) with an IC50 of 0.1 nM. It is intended for research use only. In vivo, AMG 579 has shown a statistically significant reduction of PCP-induced behavior in rats over a 2-hour period, with a minimum effective dose for efficacy in the PCP-LMA model determined to be 0.3 mg/kg. In dogs, it exhibits a superior oral bioavailability of 72%. One clinical trial (NCT01568203) is listed, sponsored by Amgen for Schizophrenia, with a start date of 2011-09, and it is in Phase 1.
- Potent, selective, and efficacious PDE10A inhibitor
- Demonstrates in vivo efficacy in reducing PCP-induced behavior in rats
- Exhibits superior oral bioavailability in dogs
- Underwent early-phase clinical trials for Schizophrenia
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Medchemexpress LLC HY-19830 5mg Medchemexpress, AN3199 CAS:1187187-10-5 Purity:>98%
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Medchemexpress, HY-19830 5mg AN3199 CAS:1187187-10-5 AN3199 is a PDE4 inhibitor with an IC50 of 94.5 nM. AN3199 can be used for the research of inflammation-associated diseases such as asthma and chronic obstructive pulmonary disease (COPD). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 52805-36-4 | 4-Benzyloxybenzonitrile | Oakwood Chemical | MFCD00079701 | 209.248 | C14H11NO | 99.000 | N#Cc1ccc(OCc2ccccc2)cc1 | 1g | 537711442
4-Benzyloxybenzonitrile | Oakwood Chemical | 52805-36-4 | MFCD00079701 | 209.248 | C14H11NO | 99.000 | N#Cc1ccc(OCc2ccccc2)cc1 | 1g | 537711442
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Medchemexpress LLC HY-104074 5mg Medchemexpress, Pocapavir CAS:146949-21-5 Purity:>98%
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Medchemexpress, HY-104074 5mg Pocapavir CAS:146949-21-5 Pocapavir is an investigational enterovirus (EV) capsid inhibitor. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Quizalofop-p-ethyl ((R)-Quizalofop ethyl) | 100646-51-3 | 99.1% | 200 MG
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Quizalofop-P-ethyl is a low-toxicity herbicide, characterized as a highly selective, new type of post-emergence herbicide for dryland crops. It demonstrates high selectivity between gramineous weeds and dicotyledonous crops, offering effective control against gramineous weeds in broadleaf crop fields.
- This compound inhibits the growth of a specific aquatic microorganism and reduces its chlorophyll and protein content.
- It impacts photosynthesis by suppressing the expression of photosynthesis-related genes.
- The compound encourages the expression of a gene related to microcystin, stimulating the synthesis and release of microcystin, which can lead to water environment pollution.
- It also increases MDA content in the aquatic microorganism and enhances the activities of SOD and CAT, inducing oxidative stress.
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eMolecules 279261-80-2 | 4-Bromo-2-chlorophenetole | Apollo Scientific | MFCD09835099 | 235.510 | C8H8BrClO | 98.000 | CCOc1ccc(Br)cc1Cl | 1g | 562451627
4-Bromo-2-chlorophenetole | Apollo Scientific | 279261-80-2 | MFCD09835099 | 235.510 | C8H8BrClO | 98.000 | CCOc1ccc(Br)cc1Cl | 1g | 562451627
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