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Filtered Search Results
Medchemexpress LLC N-[4-(4-chlorophenyl)sulfonyl-4-(2,5-difluorophenyl)cyclohexyl]-1,1,1-trifluoromethanesulfonamide | 677772-84-8 | MFCD09970622 | >98.0% | C19H17ClF5NO4S2 | 10MG
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MRK-560 is a PSEN1-selective γ-secretase inhibitor used as a research probe for amyloid precursor protein processing. It is orally active and brain-penetrant, and has been shown in preclinical studies to reduce amyloid-β peptide levels in brain and cerebrospinal fluid. The compound is supplied as a solid powder with documented storage and solubility recommendations for in vitro and in vivo applications.
- Selective inhibition of PSEN1-containing γ-secretase complexes.
- Orally active and brain-penetrant for central nervous system studies.
- Reduces amyloid-β peptide levels in preclinical models.
- High solubility in DMSO and multiple documented in vivo formulation options.
- Supplied as a powder with recommended cold-storage conditions for stability.
- Well-characterized chemical identity with published molecular and structural data.
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Medchemexpress LLC HY-101281 5mg Medchemexpress, VU 6008667 CAS:2092923-21-0 Purity:>98%
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Medchemexpress, HY-101281 5mg VU 6008667 CAS:2092923-21-0 VU 6008667 is a selective negative allosteric modulator of M5 NAM with IC50s of 1.2 μM and 1.6 μM for human M5 and rat M5, respectively. High CNS penetration. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Unc0224 | HY-10929
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Unc0224
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Medchemexpress LLC HY-119254 10mg Medchemexpress, BAY-850 CAS:2099142-76-2 Purity:>98%
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Medchemexpress, HY-119254 10mg BAY-850 CAS:2099142-76-2 BAY-850 is a potent and isoform selective ATPase family AAA domain-containing protein 2 (ATAD2) inhibitor, with an IC50 of 166 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-112483 5mg Medchemexpress, QX77 CAS:1798331-92-6 Purity:>98%
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Medchemexpress, HY-112483 5mg QX77 CAS:1798331-92-6 QX77 is a chaperone-mediated autophagy (CMA) activator. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-112607 10mg Medchemexpress, Tubulin inhibitor 1 CAS:2237054-53-2 Purity:>98%
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Medchemexpress, HY-112607 10mg Tubulin inhibitor 1 CAS:2237054-53-2 Tubulin inhibitor 1 is a tubulin inhibitor, inhibits tubulin polymerization. Tubulin inhibitor 1 shows potent anti-tumor activity, casues cellular mitotic arrest in the G2/M phase, and induces cellular apoptosis. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-112683 10mg Medchemexpress, V-9302 CAS:1855871-76-9 Purity:>98%
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Medchemexpress, HY-112683 10mg V-9302 CAS:1855871-76-9 V-9302 is a competitive antagonist of transmembrane glutamine flux. V-9302 selectively and potently targets the amino acid transporter ASCT2 (SLC1A5). V-9302 inhibits ASCT2-mediated glutamine uptake (IC50=9.6 µM) in HEK-293 cells. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules Medchem Express / Cloprostenol sodium salt / 5mg / 441681794 / HY-108415 / / 55028-72-3 / [null] / 446.900 / C22H28ClNaO6
Medchem Express / Cloprostenol sodium salt / 5mg / 441681794 / HY-108415 / / 55028-72-3 / [null] / 446.900 / C22H28ClNaO6
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Medchemexpress LLC HY-10206 5mg Medchemexpress, Amuvatinib CAS:850879-09-3 Purity:>98%
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Medchemexpress, HY-10206 5mg Amuvatinib CAS:850879-09-3 Amuvatinib (MP470) is an orally bioavailable multi-targeted tyrosine kinase inhibitor with potent activity against mutant c-Kit, PDGFRα, Flt3, c-Met and c-Ret. Amuvatinib (MP470) is also a DNA repair suppressor through suppression of DNA repair protein RAD51, thereby disrupting DNA damage repair[3]. Antineoplastic activity[4]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-111803 100mg Medchemexpress, 4'-Methoxyflavonol CAS:6889-78-7 Purity:>98%
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Medchemexpress, HY-111803 100mg 4'-Methoxyflavonol CAS:6889-78-7 4'-Methoxyflavonol is a synthesized flavone/flavonol with 1, 2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) bilayers. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-11079 50mg Medchemexpress, A-803467 CAS:944261-79-4 Purity:>98%
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Medchemexpress, HY-11079 50mg A-803467 CAS:944261-79-4 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Au-15330 | 2380274-50-8 | 99.9% | C39H49N9O5S | 10MG
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AU-15330 is a proteolysis-targeting chimera (PROTAC) that selectively degrades SWI/SNF ATPase subunits SMARCA2 and SMARCA4. It demonstrates potent antitumor activity in prostate cancer xenograft models and shows synergy with androgen receptor antagonists in preclinical studies.
- Selective degradation of SMARCA2 and SMARCA4
- Demonstrated antitumor activity in prostate cancer xenograft models
- Synergizes with androgen receptor antagonists
- High reported purity (≈99.9%) suitable for research use
- Solid, off-white to yellow appearance for easy handling
- Storage-stable when kept under recommended conditions
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Medchemexpress LLC O-desmethyl galanthamine | 60755-80-8 | MFCD07369289 | 99.7% | C16H19NO3 | 10MG
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O-desmethyl galanthamine (sanguinine) is a galanthamine-type alkaloid used as a research reagent and reference standard. It acts as a reversible acetylcholinesterase (AChE) inhibitor and is used in biochemical assays to evaluate AChE activity and inhibitor potency; reported IC50 = 1.83 μM. Supplied as a powder for analytical and research use.
- Reversible acetylcholinesterase inhibitor with reported IC50 1.83 μM.
- High purity (99.7%) suitable for analytical applications.
- Suitable as a reference standard in biochemical and pharmacological assays.
- Powder form compatible with common laboratory solvents.
- Molecular formula C16H19NO3; molecular weight 273.33 g·mol⁻¹.
- Available in small quantities for research use.
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Medchemexpress LLC HY-100639 5mg Medchemexpress, Roflumilast N-oxide CAS:292135-78-5 Purity:>98%
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Medchemexpress, HY-100639 5mg Roflumilast N-oxide CAS:292135-78-5 Roflumilast N-oxide is a PDE type 4 inhibitor. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-101294 5mg Medchemexpress, TPPU CAS:1222780-33-7 Purity:>98%
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Medchemexpress, HY-101294 5mg TPPU CAS:1222780-33-7 TTPU is a soluble epoxide hydrolase (sEH) inhibitor with IC50 values of 37 and 3.7 nM for monkey and human sEH, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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