Sulfanilides
Aobchem 3-Methylsulfonylaminophenylboronic acid, AOBCHEM USA 12456-5G. 148355-75-3. MFCD02179478
3-Methylsulfonylaminophenylboronic acid, AOBCHEM USA 12456-5G. 148355-75-3. MFCD02179478
Medchemexpress LLC (R)-Bay-899 | 2988191-40-6 | 99.9% | 459.45 | C25H19F2N5O2 | 5 MG
(R)-BAY-899 is the R-enantiomer of BAY-899, an orally active, selective luteinizing hormone receptor (LH-R) antagonist used as a research tool for in vitro and in vivo studies. Supplied as an off-white to light yellow solid, the compound is characterized by high purity and includes documented solubility and storage conditions for laboratory applications.
- Selective LH-R antagonist for receptor signaling studies.
- High purity suitable for analytical and biological assays.
- Documented solubility in DMSO and multiple in vivo formulations.
- Stable powder storage at -20°C or 4°C with defined solvent stability.
- Available in small solid and solution pack sizes for research use.
Medchemexpress LLC (R)-BAY-899 | 2988191-40-6 | 99.9% | 100 MG
(R)-BAY-899 is the R-enantiomer of BAY-899, functioning as an orally active and selective luteinizing hormone receptor (LH-R) antagonist. It exhibits IC50 values of 185 nM for human LH (hLH) and 46 nM for rat LH (rLH).
- Orally active
- Selective LH-R antagonist
- IC50 of 185 nM for human LH
- IC50 of 46 nM for rat LH
- Solid appearance
- Off-white to light yellow color
- High purity (99.9%)
- Soluble in DMSO (125 mg/mL)
Medchemexpress LLC BAY-899 | 2471967-92-5 | 99.9% | 100 MG
BAY-899 is a chemical probe and an orally active, selective luteinizing hormone receptor (LH-R) antagonist. It is characterized by IC50s of 185 nM for human LH and 46 nM for rat LH, and has shown efficacy in reducing sex hormone levels in vivo. This product is intended for research use only.
- High purity of 99.93%
- Selective luteinizing hormone receptor (LH-R) antagonist
- Reduces sex hormone levels
- Potent inhibition with IC50s of 185 nM for human LH and 46 nM for rat LH
- Available as a white to off-white solid
- Stable as powder for up to 3 years at -20°C or 2 years at 4°C
Medchemexpress LLC N-(cis-3-(methyl(7H-pyrrolo(2,3-d)pyrimidin-4-yl)amino)cyclobutyl)-1-propanesulfonamide | 1622902-68-4 | MFCD30187577 | >98.0% | 323.41 | C14H21N5O2S | 100 MG
Abrocitinib is a potent, orally active, and selective JAK1 inhibitor supplied as a research-grade analytical standard. It is provided as a purified solid suitable for in vitro pharmacology, assay development, and analytical reference. Chemical identity: N-(cis-3-(methyl(7H-pyrrolo(2,3-d)pyrimidin-4-yl)amino)cyclobutyl)-1-propanesulfonamide; CAS 1622902-68-4; formula C14H21N5O2S; molecular weight 323.41 g/mol.
- Potent, selective JAK1 inhibitor for mechanistic and screening studies.
- High purity (>98.0%) suitable for analytical and assay use.
- Solid powder form for accurate weighing and formulation.
- Well-characterized chemical identity with CAS 1622902-68-4.
- Appropriate for in vitro pharmacology and compound profiling.
Medchemexpress LLC Dpm-1001 | 1471172-27-6 | 99.8% | 5 MG
DPM-1001 is a small-molecule, orally bioavailable, non-competitive inhibitor of protein-tyrosine phosphatase 1B (PTP1B) with a reported IC50 of approximately 100 nM. It is used in preclinical research to investigate insulin and leptin signaling and metabolic regulation.
- Non-competitive inhibitor of PTP1B (IC50 ≈ 100 nM).
- Orally bioavailable in preclinical models.
- Supports research into insulin and leptin signaling pathways.
- High reported purity suitable for biochemical assays.
- Stored cold to maintain stability and activity.
![Medchemexpress LLC 3-methoxy-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-4-(2-morpholin-4-yl-2-oxoethoxy)benzamide | 781628-99-7 | 98.0% | 483.54 g/mol | C24H25N3O6S | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000237142.png-250.jpg)
Medchemexpress LLC 3-methoxy-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-4-(2-morpholin-4-yl-2-oxoethoxy)benzamide | 781628-99-7 | 98.0% | 483.54 g/mol | C24H25N3O6S | 10MG
SBI-477 is a small-molecule chemical probe that stimulates insulin signaling by deactivating the transcription factor MondoA, resulting in reduced expression of insulin-pathway suppressors and coordinated inhibition of triacylglyceride synthesis while enhancing basal glucose uptake in human skeletal myocytes.
- Deactivates MondoA to stimulate insulin signaling.
- Reduces TXNIP and ARRDC4 expression.
- Inhibits triacylglyceride synthesis and increases basal glucose uptake.
- Provided as a solid powder, supplied in a 10 mg package.
- High purity: 98.0%.
- Recommended storage: powder at -20°C (long-term) or 4°C (shorter term).
Medchemexpress LLC Litronesib Racemate | 546111-97-1 | 99.2% | 511.70 | 100 MG
Litronesib Racemate is the racemate of litronesib, a selective, allosteric inhibitor of kinesin Eg5. It is designed for various research applications.
- Selective, allosteric inhibitor of kinesin Eg5
- Targets kinesin
- Involved in cell cycle/DNA damage pathway
- Involved in cytoskeleton pathway
Selleck Chemical LLC Defactinib
Defactinib (VS-6063 PF-04554878) is a selective and orally active FAK inhibitor Phase 2
Medchemexpress LLC Selexipag | 475086-01-2 | 496.62 | 100 MG
Selexipag (NS-304) is an orally available and potent agonist for the Prostacyclin (PGI2) receptor (IP receptor). It is also described as an orally available and long-acting IP receptor agonist prodrug, with its active form being MRE-269.
- Orally available and potent agonist for the prostacyclin (PGI2) receptor (IP receptor)
- Long-acting IP receptor agonist prodrug; active form is MRE-269
- Inhibits binding of [3H]Iloprost to human and rat IP receptors
- Increases intracellular cAMP levels in hIP-CHO cells
- Inhibits platelet aggregation in humans and monkeys
Medchemexpress LLC BAY-899 | 2471967-92-5 | 99.9% | 50 MG
BAY-899 is an orally active and selective luteinizing hormone receptor (LH-R) antagonist, functioning as a chemical probe. It demonstrates IC50s of 185 nM for human LH (hLH) and 46 nM for rat LH (rLH), and is capable of reducing sex hormone levels. In vivo studies have shown that BAY-899 can reduce serum estradiol levels in intact female rats and exhibits a half-life of approximately 11-12 hours in Wistar rats.
- Orally active and selective luteinizing hormone receptor (LH-R) antagonist
- IC50s of 185 nM for human LH (hLH) and 46 nM for rat LH (rLH)
- Capable of reducing sex hormone levels
- Inhibits human ERG expressed in HEK293 cells with an IC50 of 10.6 μM
- Reduced serum estradiol levels in intact female rats
Sigma Aldrich Fine Chemicals Biosciences Methazolamide Fine Chemical | 554-57-4 | MFCD00083416 | 1 G
Methazolamide fine chemical | Purity: N/A | M.W.: 236.27 | 554-57-4 | MFCD00083416 | 1g
