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Filtered Search Results
Medchemexpress LLC PD153035 hydrochloride | 183322-45-4 | 99.5% | 50 MG
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PD153035 hydrochloride is the hydrochloride salt of a potent epidermal growth factor receptor (EGFR) inhibitor used in biochemical and cellular research. It is supplied as a high-purity, well-characterized small-molecule reagent with defined solubility and storage recommendations.
- Potent EGFR inhibitor with reported Ki = 6 pM and IC50 = 25 pM.
- High purity: 99.48%.
- Molecular formula C16H15BrClN3O2; molecular weight 396.67 g/mol.
- Soluble in DMSO (4 mg/mL); insoluble in water (< 0.1 mg/mL).
- Recommended storage: solid at 4°C; in solution -80°C (6 months) or -20°C (1 month).
- Supplied as a 50 mg package for research use.
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Sigma Aldrich Fine Chemicals Biosciences Acetaminophen BioXtra, >=99.0% | 103-90-2 | MFCD00002328 | 1KG
Acetaminophen BioXtra, >=99.0% | Purity: >=99.0% | Mol Wt: 151.16 | 103-90-2 | MFCD00002328 | 1KG
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Medchemexpress LLC ZM39923 hydrochloride | 1021868-92-7 | MFCD04974534 | 99.8% | 367.91 g/mol | C23H26ClNO | 5MG
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ZM39923 hydrochloride is a research-grade small molecule that acts primarily as a JAK3 inhibitor (pIC50 = 7.1) and also potently inhibits tissue transglutaminase (TGM2) (IC50 ≈ 10 nM). It displays weaker activity against EGFR and JAK1 and minimal activity versus Lck and CDK4. Supplied as the hydrochloride salt with high reported purity, it is intended for laboratory research use only.
- JAK3 inhibitor with pIC50 7.1.
- Potent tissue transglutaminase (TGM2) inhibition (IC50 ≈ 10 nM).
- Hydrochloride salt form for improved stability and handling.
- High reported purity (around 99.8%).
- Available as solid and as a DMSO solution format.
- Intended for research use only; not for diagnostic or therapeutic use.
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Medchemexpress LLC 8-methyl-8-azabicyclo[3.2.1]octan-3-yl 2-oxo-1,4-dihydroquinazoline-3-carboxylate hydrochloride | 131780-48-8 | MFCD00911718 | 99.0% | 351.83 g/mol | C17H22ClN3O3 | 5 MG
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DAU 5884 hydrochloride is a potent, selective muscarinic M3 receptor antagonist provided as the hydrochloride salt for research use. It is used in vitro to study muscarinic receptor-mediated signaling, including methacholine-dependent cell proliferation and smooth muscle contractility.
- Potent M3 receptor antagonist suitable for in vitro pharmacology.
- Inhibits methacholine-dependent cell proliferation and muscle contractility.
- High reported purity for reliable experimental results.
- Available in small milligram quantities for screening and characterization.
- Soluble in water and DMSO for diverse assay formats.
- Provided as a hydrochloride salt for improved stability and handling.
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Medchemexpress LLC CC-115 hydrochloride | 1300118-55-1 | 98.0% | 372.81 | 100 MG
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CC-115 hydrochloride is a potent dual DNA-PK and mTOR kinase inhibitor that blocks both mTORC1 and mTORC2 signaling. It inhibits PC-3 cell proliferation and demonstrates selectivity against other protein kinases and PIKKs, including good selectivity against PI3K-alpha, ATR, and ATM. It shows good in vivo PK profiles across multiple species.
- Potent and dual DNA-PK and mTOR kinase inhibitor (IC50s of 13 nM and 21 nM respectively)
- Blocks both mTORC1 and mTORC2 signaling
- Inhibits PC-3 cells proliferation with an IC50 of 138 nM
- Demonstrates selectivity against other protein kinases and PIKKs
- Shows good in vivo PK profiles across multiple species (53% in mouse, 76% in rat, and ~100% in dog oral bioavailability)
- Leads to significant tumor volume reductions and sustains inhibition in vivo
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Medchemexpress LLC Ly266097 hydrochloride | 172895-39-5 | MFCD00949080 | 99.6% | 407.33 | C21H24Cl2N2O2 | 10 MG
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LY266097 hydrochloride is a selective 5-HT2B receptor antagonist supplied as the hydrochloride salt for laboratory research. It is used to study serotonin 5-HT2 receptor pharmacology and is provided at high purity for in vitro and preclinical applications.
- Selective 5-HT2B receptor antagonist.
- Reported pKi values: 5-HT2A 7.7; 5-HT2B 9.8; 5-HT2C 7.6.
- High purity (99.6%) suitable for research use.
- Supplied as a hydrochloride salt in small milligram quantities for laboratory studies.
- Molecular formula C21H24Cl2N2O2; molecular weight 407.33.
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Medchemexpress LLC 4-nitrophthalonitrile | 31643-49-9 | MFCD00040301 | 99.9% | 173.13 g·mol⁻¹ | C8H3N3O2 | 1000 G
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4-Nitrophthalonitrile is an organic reagent used as a synthetic building block and intermediate for preparing phthalonitrile derivatives and functionalized aromatic compounds. It is supplied as a high-purity, crystalline solid intended for research and development applications in organic synthesis and materials chemistry.
- High reported purity ≈99.9% (vendor documents show 99.89-99.99%).
- White to off-white solid suitable for synthetic use.
- Soluble in DMSO (≈50 mg/mL) with reported protocols for in vivo vehicles.
- Stable when stored as powder at -20°C; solvent storage conditions specified.
- Analytical documentation available including COA, SDS, H-NMR, and RP-HPLC.
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Aobchem AOBCHEM
5000945711 1 3-DIBROMO-5-FLUORO-2 4-DIMET
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eMolecules 74283-34-4 | 2,4-Diaminophenol sulfate | MFCD01321156 | 1g
Combi-Blocks, Inc. | 2,4-Diaminophenol sulfate | 1g | 603144863 | QC-1959 | 98.000 | 74283-34-4 | MFCD01321156 | 222.220 | C6H10N2O5S
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000377299 SM-164 HYDROCHLORID 100MG
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Medchemexpress LLC Biotin-4-aminophenol | 901770-40-9 | MFCD29037927 | 99.5% | 335.42 g/mol | C16H21N3O3S | 5 MG
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Biotin-4-aminophenol is a biotin-phenol analog used to generate phenoxyl radicals that selectively label tyrosine residues in proteins, facilitating proximity-dependent biotinylation and protein labeling assays. Supplied as a high-purity solid, it is suitable for biochemical and cell biology workflows and is soluble in DMSO for preparing concentrated stock solutions.
- High purity suitable for biochemical assays.
- Generates phenoxyl radicals that conjugate selectively to tyrosine residues.
- Enables proximity-dependent biotinylation and targeted protein labeling workflows.
- Provided in small solid quantities for laboratory-scale experiments.
- Soluble in DMSO for easy preparation of stock solutions.
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eMolecules 887919-35-9 | Dichlorobis[di-tert-butyl(4-dimethylaminophenyl)phosphine]palladium(II) | Accela ChemBio (ASD) | MFCD09265123 | 708.080 | C32H56Cl2N2P2Pd | 97.000 | [Cl-].[Cl-].[Pd++].CN(C)c1ccc(cc1)P(C(C)(C)C)C(C)(C)C.CN(C)c1ccc(cc1)P(C(C)(C)C)C(C)(C)C | 1g | 510408947
Dichlorobis[di-tert-butyl(4-dimethylaminophenyl)phosphine]palladium(II) | Accela ChemBio (ASD) | 887919-35-9 | MFCD09265123 | 708.080 | C32H56Cl2N2P2Pd | 97.000 | [Cl-].[Cl-].[Pd++].CN(C)c1ccc(cc1)P(C(C)(C)C)C(C)(C)C.CN(C)c1ccc(cc1)P(C(C)(C)C)C(C)(C)C | 1g | 510408947
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000378622 FTI-277 HYDROCHLORI 50MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000381127 ACETAMINOPHEN IMPURI 100MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000379217 PIK-75 HYDROCHLORID 100MG
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