Aminophenols
Medchemexpress LLC RS102895 hydrochloride | 1173022-16-6 | 99.9% | 426.86 | 50 MG
Abaucin hydrochloride (RS102895 hydrochloride) is a potent CCR2 antagonist (IC50 = 360 nM) that also inhibits human α1a and α1d receptors, and the rat brain cortex 5HT1a receptor. It ameliorates extracellular matrix (ECM) protein expression and blocks fibronectin and type IV collagen expression in high glucose-stimulated mesangial cells.
- Potent CCR2 antagonist.
- Inhibits human α1a and α1d receptors.
- Suppresses MCP-1 receptor activity.
- Ameliorates extracellular matrix protein expression.
- Blocks fibronectin and type IV collagen expression.
- Reverses NR2B, nNOS, and SIGIRR expression in spinal cord.
Medchemexpress LLC MK-8033 hydrochloride | 1283000-43-0 | MFCD18633221 | ≥98.0% | C24H22Cl2N6O | 10MG
MK-8033 hydrochloride is a small-molecule, ATP-competitive dual inhibitor of c-Met and Ron kinases supplied as the hydrochloride salt for research use. It has been used in oncology research and was evaluated in early clinical trials; supplier listings report high purity and analytical characterization for laboratory applications.
- Potent dual c-Met and Ron kinase inhibitor
- Hydrochloride salt form
- Purity ≥98.0%
- Characterized by molecular formula and molecular weight
- Intended for research use in oncology studies
- Documented in early-phase clinical investigations
Medchemexpress LLC CC-401 (hydrochloride) | 1438391-30-0 | 99.35% | 1 ML
CC-401 hydrochloride is a potent inhibitor of all three forms of JNK. It competitively binds the ATP binding site in JNK, inhibiting the phosphorylation of the N-terminal activation domain of the transcription factor c-Jun. It offers at least 40-fold selectivity for JNK compared with other related kinases.
- Potent JNK inhibitor
- High selectivity for JNK
- Inhibits phosphorylation of c-Jun
- Suitable for laboratory centrifugation and storage
eMolecules 1448584-12-0 | Medchem Express | S55746 | 5mg | 446260465 | HY-117288 | 710.831 | C43H42N4O6
Ambeed | (R)-2-(6-Methylpyridin-2-yl)-4-phenyl-45-dihydrooxazole | 100mg | 649269024 | A1476160 | 199277-73-1 | 238.290 | C15H14N2O
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Medchemexpress LLC Sotorasib-d7 | 2296729-00-3 | 98.9% | 567.64 | 10 MG
Sotorasib-d7 is a deuterium-labeled Sotorasib and a first-in-class, orally bioavailable, and selective KRAS G12C covalent inhibitor. It irreversibly inhibits KRAS G12C by locking it in an inactive GDP-bound state, leading to the regression of KRAS G12C-mutated locally advanced or metastatic non-small cell lung cancer (NSCLC).
- Deuterium-labeled Sotorasib.
- First-in-class, orally bioavailable, and selective KRAS G12C covalent inhibitor.
- Irreversibly inhibits KRAS G12C by locking it in an inactive GDP-bound state.
- Leads to the regression of KRAS G12C-mutated locally advanced or metastatic non-small cell lung cancer (NSCLC).
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC RS100329 hydrochloride | 1215654-26-4 | MFCD00953081 | 99.6% | 462.89 g·mol⁻1 | C20H26ClF3N4O3 | 50 MG
RS100329 hydrochloride is the hydrochloride salt of RS100329, a potent and selective α1A-adrenoceptor antagonist used in pharmacological research. It is supplied as a white to off-white solid with high reported purity, and is suitable for in vitro and in vivo studies of α1A-adrenoceptor signaling and pharmacology.
- High purity (99.57%), white to off-white solid.
- Selective α1A-adrenoceptor antagonist for receptor pharmacology studies.
- Suitable for in vitro and in vivo research applications.
- Molecular weight 462.89 g·mol⁻1; formula C20H26ClF3N4O3.
- Store at 4°C and protect from light; solutions: -80°C (6 months) or -20°C (1 month).
- Supplied in 50 mg quantities.
Medchemexpress LLC Ozanimod (hydrochloride) | 1618636-37-5 | 98.1% | 1 ML
Ozanimod hydrochloride 10 mM in DMSO (1 mL) is a ready-to-use research reagent for studying sphingosine 1-phosphate (S1P) receptor modulation in preclinical and biochemical assays. Supplied as a solution to improve handling and reproducibility. For research use only; not for human use.
- Ready-to-use 10 mM solution in DMSO.
- Supplied as a 1 mL aliquot for small-scale experiments.
- Listed purity 98.1% for consistent experimental results.
- Molecular weight 440.92 g/mol and formula C23H25ClN4O3.
- Intended for research use only; not for clinical or human use.
Medchemexpress LLC Ozanimod hydrochloride | 1618636-37-5 | 98.1% | 5 MG
Ozanimod hydrochloride is the hydrochloride salt of ozanimod, a selective sphingosine 1-phosphate (S1P) receptor modulator used in research on immune-mediated disorders such as relapsing multiple sclerosis. It is supplied as a white to off-white solid with high purity for in vitro and in vivo pharmacology studies.
- High purity (98.1%).
- Molecular weight 440.92 g/mol; formula C23H25ClN4O3.
- Soluble in DMSO at ≥ 200 mg/mL for stock solutions.
- Suitable for in vitro and in vivo pharmacology applications.
- Supplied as a 5 MG quantity.
- Store sealed at 4°C; in solvent store -80°C for up to 6 months or -20°C for 1 month.
Medchemexpress LLC His-pro hydrochloride | 2415727-78-3 | 99.8% | 288.73 | 25 MG
His-Pro hydrochloride is a dipeptide consisting of histidyl and proline. This product is intended for research use only.
- Dipeptide composed of histidyl and proline.
- High purity of 99.84%.
- Detailed storage conditions provided.
- Solubility information available.
Cayman Chemical Acetaminophen, Purity: ≥98%, CAS: 103-90-2, 500 g
An analgesic and antipyretic compound; an inhibitor of COX-2 that is selective over COX-1 (IC50s = 113.7 and 25.8 µM, respectively, in human blood ex vivo); induces ferroptotic cell death in primary mouse hepatocytes; has a metabolite that depletes glutathione reserves in the liver
Medchemexpress LLC V-0219 hydrochloride | 2922283-73-4 | 99.39% | C20H26ClF3N4O2 | 25 MG
V-0219 hydrochloride (Compound 9) is an orally active, positive allosteric modulator (PAM) of the glucagon-like peptide-1 receptor (GLP-1R). It can be used for obesity-associated diabetes research.
- Orally active, positive allosteric modulator (PAM) of the glucagon-like peptide-1 receptor (GLP-1R)
- Can be used for obesity-associated diabetes research
- IC50 and target: GLP-1R
c1cc(Cl)cc(Cl)c1 | 0.25g | 200619803](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502180169.JPG-250.jpg)
eMolecules 617710-53-9 | (R)-1-(3,5-DICHLOROPHENYL)ETHYLAMINE | AstaTech | MFCD07772552 | 190.070 | C8H9Cl2N | 95.000 | C[C@@H](N)c1cc(Cl)cc(Cl)c1 | 0.25g | 200619803
(R)-1-(3,5-DICHLOROPHENYL)ETHYLAMINE | AstaTech | 617710-53-9 | MFCD07772552 | 190.070 | C8H9Cl2N | 95.000 | C[C@@H](N)c1cc(Cl)cc(Cl)c1 | 0.25g | 200619803
![Medchemexpress LLC Benzamide, 2-(3-aminopropoxy)-5-chloro-N-(1,1-dioxidobenzo[b]thien-6-yl)-hydrochloride | 2415263-08-8 | 98.7% | 429.32 | C18H18Cl2N2O4S | 5MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000236424.png-250.jpg)
Medchemexpress LLC Benzamide, 2-(3-aminopropoxy)-5-chloro-N-(1,1-dioxidobenzo[b]thien-6-yl)-hydrochloride | 2415263-08-8 | 98.7% | 429.32 | C18H18Cl2N2O4S | 5MG
HJC0416 hydrochloride is the hydrochloride salt of a small-molecule STAT3 inhibitor that reduces STAT3 phosphorylation, inhibits cell proliferation in vitro, and has shown antitumor activity in preclinical models. It is supplied as a white to off-white solid with high analytical purity and is intended for laboratory research use only.
- Potent STAT3 inhibitor with reported in vitro IC50 0.04-1.97 μM.
- Demonstrated oral bioavailability and antitumor activity in preclinical models.
- High purity (98.7% by HPLC).
- Molecular weight 429.32 and chemical formula C18H18Cl2N2O4S.
- White to off-white solid appearance.
- Storage: -20 °C, protect from light; in solvent: -80 °C (6 months) or -20 °C (1 month).
- For laboratory research use only; not for human or clinical use.
Medchemexpress LLC Ozanimod hydrochloride | 1618636-37-5 | 98.1% | 10 MG
Ozanimod hydrochloride is the hydrochloride salt of ozanimod (RPC-1063), a selective sphingosine 1-phosphate (S1P) receptor modulator supplied for laboratory research use only. It is used in studies of immune modulation and relapsing multiple sclerosis.
- Purity 98.1%.
- Molecular weight 440.92.
- Molecular formula C23H25ClN4O3.
- White to off-white solid; also available as 10 mM solution in DMSO.
- Storage: 4°C sealed; in solvent: -80°C (6 months), -20°C (1 month).
- Intended for laboratory research on S1P receptor biology and multiple sclerosis models.
Sigma Aldrich Fine Chemicals Biosciences SKI II >=98% (HPLC), solid | 312636-16-1 | MFCD00733553 | 50MG
SKI II >=98% (HPLC), solid | Purity: >=98% (HPLC) | Mol Wt: 302.78 | 312636-16-1 | MFCD00733553 | 50MG
