Aminophenols
TARGETMOL CHEMICALS INC TMS 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. TMS (23'45'-Tetramethoxystilbene) is a very selective and potent competitive inhibitor of P450 1B1 (CYP1A1). purity: 99%
TARGETMOL CHEMICALS INC ABT530 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. ABT530 (Pibrentasvir) is an HCV NS5A inhibitor with EC50s ranging from 1.4-5.0 pM against HCV replicons containing NS5A from genotypes 1-6. purity: 99%
Medchemexpress LLC Afm32a hydrochloride | 2988594-85-8 | 99.4% | 517.00 | 1 MG
Afm32a hydrochloride | 2988594-85-8 | 99.4% | 517.00 | 1 MG
TARGETMOL CHEMICALS INC ECOPLADIB 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Ecopladib (PLA 725) is a sub-micromolar inhibitor of cytosolic phospholipase A2(alpha) (cPLA2(alpha)) with IC50s of 0.15 uM and 0.11 uM in the GLU micelle and rat whole blood assays respectively. purity: 99%
Medchemexpress LLC Rhosin (hydrochloride) | 1281870-42-5 | 99.9% | 394.86 | 25 MG
Rhosin hydrochloride is a potent and specific inhibitor of the RhoA subfamily of Rho GTPases. It specifically binds to RhoA to inhibit RhoA-GEF interaction without interacting with Cdc42, Rac1, or the GEF, LARG. This compound induces cell apoptosis and promotes stress resiliency by enhancing D1-MSN plasticity and reducing hyperexcitability.
- Potent and specific inhibitor of the RhoA subfamily of Rho GTPases.
- Specifically binds to RhoA, inhibiting RhoA-GEF interaction.
- Induces cell apoptosis.
- Promotes stress resiliency.
- Reduces RhoA and p-MLC1 activities.
- Prevents social avoidance and blocks sucrose preference deficits.
- Attenuates stress-induced social avoidance and hyperexcitability.
- Enhances spine density in defeat mice.
Medchemexpress LLC Di-Pal-MTO | 1349197-90-5 | 98.4% | 917.27 | 1 MG
di-Pal-MTO is a palm oil-based lipid produced by combining the anticancer agent mitoxantrone (MTO) with palmitoleic acid. When nanoparticles of mono-Pal-MTO and di-Pal-MTO are combined in a molar ratio of 1:1, they show effective siRNA cell delivery and enhance anticancer activity.
- Effective siRNA cell delivery
- Enhanced anticancer activity
- Reduces tumor cell viability by 81%
- Reduces tumor size by 83%
Medchemexpress LLC AFM-30a hydrochloride | 99.8% | 502.97 | 1 MG
AFM-30a hydrochloride is a potent and selective protein arginine deiminase 2 (PAD2) inhibitor. It binds to PAD2 with an EC50 value of 9.5 μM and inhibits H3 citrullination with an EC50 value of 0.4 μM. This product is suitable for research into certain cancers and various autoimmune diseases, including rheumatoid arthritis, multiple sclerosis, lupus, and ulcerative colitis.
- Potent and selective PAD2 inhibitor.
- Inhibits H3 citrullination.
- Useful for cancer research.
- Useful for autoimmune disease research.
- Suppresses NLRP3 signaling.
- Decreases airway remodeling.
- Shows low cell cytotoxicity.
Medchemexpress LLC BODIPY-581/591 NHS ester | 150152-70-8 | 98.67% | 489.28 | 10 MG
BODIPY-581/591 NHS ester is a bright, red fluorescent dye used for labeling amine-containing biomolecules, with excitation at 581 nm and emission at 591 nm.
- Solid, blue to black appearance.
- Soluble in DMSO at 25 mg/mL (51.10 mM); requires ultrasonic; hygroscopic DMSO may impact solubility.
- Ships at room temperature in continental US.
- Store at -20°C, sealed, away from moisture and light.
- In solvent, store at -80°C for 6 months; -20°C for 1 month (sealed, away from moisture and light).
Medchemexpress LLC AFM-30a (hydrochloride) | 99.7% | 502.97 | 10 MG
AFM-30a hydrochloride is a potent and highly selective inhibitor of protein arginine deiminase 2 (PAD2). It binds to PAD2 with an EC50 value of 9.5 μM and inhibits H3 citrullination with an EC50 value of 0.4 μM. This compound is suitable for research into certain cancers and various autoimmune diseases, such as rheumatoid arthritis (RA), multiple sclerosis, lupus, and ulcerative colitis.
- Potent protein arginine deiminase 2 (PAD2) inhibitor.
- Demonstrates excellent PAD2-selectivity.
- Binds to PAD2 with an EC50 value of 9.5 μM.
- Inhibits H3 citrullination with an EC50 value of 0.4 μM.
- Applicable for research on certain cancers and various autoimmune diseases, including rheumatoid arthritis (RA), multiple sclerosis, lupus, and ulcerative colitis.
- Exhibits low cytotoxicity in HEK293T/PAD2 cells.
- Suppresses NLRP3 signaling and reduces airway remodeling in PAD2-/-transgenic mice.
Medchemexpress LLC BODIPY-581/591 NHS ester | 150152-70-8 | 98.67% | 489.28 | 5 MG
BODIPY-581/591 NHS ester is a bright, red fluorescent dye used for the labeling of amine containing biomolecules. It exhibits excitation at 581 nm and emission at 591 nm.
- It is a bright, red fluorescent dye.
- It has an excitation wavelength of 581 nm.
- It has an emission wavelength of 591 nm.
- It can be used for labeling biomolecules that contain amine groups.
Medchemexpress LLC WR99210 hydrochlorid 5mg | 30711-93-4 | 5 MG
WR99210 hydrochloride is a potent dihydrofolate reductase (DHFR) inhibitor used in research on Plasmodium spp. and Toxoplasma gondii, and commonly used for selection of Plasmodium transfectants. The compound is supplied as the hydrochloride salt and is intended for laboratory research use only.
- Potent DHFR inhibitor (IC50 <0.075 nM).
- Used for antimalarial research and parasite selection.
- Supplied as a hydrochloride salt for improved solubility.
- Suitable for storage at -20°C in sealed containers away from moisture.
- Available in small research quantities for lab use (e.g., 5 mg).