Aminophenols
Medchemexpress LLC CPI-455 hydrochloride | 2095432-28-1 | 100.0% | 314.77 g/mol | C16H15ClN4O | 5 MG
CPI-455 hydrochloride is the hydrochloride salt of a potent, selective pan-KDM5 histone demethylase inhibitor used in biochemical and cellular epigenetic research. It inhibits KDM5A with an IC50 of ≈10 nM, elevates global H3K4 trimethylation, and has been applied in studies of drug-tolerant persister cancer cells.
- Potent pan-KDM5 inhibitor (IC50 ≈ 10 nM for KDM5A).
- Elevates global H3K4 trimethylation in cellular assays.
- Hydrochloride salt form for enhanced stability and handling.
- Molecular formula C16H15ClN4O; molecular weight 314.77 g/mol.
- CAS number 2095432-28-1 for unambiguous identification.
- High purity (listed as 99.95%), suitable for research applications.
- Soluble in DMSO; water insoluble.
- Available in small laboratory pack sizes for screening and mechanistic studies.
Medchemexpress LLC Lavendustin B | 125697-91-8 | MFCD00133446 | 98.0% | 365.38 | C21H19NO5 | 5 MG
Lavendustin B is a small-molecule research reagent that inhibits HIV-1 integrase interaction with LEDGF/p75, functions as an ATP-competitive GLUT1 inhibitor, and exhibits weak tyrosine kinase inhibition. Supplied as a solid for laboratory research use, it is characterized by its CAS number 125697-91-8 and defined molecular properties.
- High purity (98.0%).
- Molecular weight 365.38 g/mol.
- Chemical formula C21H19NO5.
- Available in small milligram quantities suitable for screening and assays.
- Stable as powder when stored at -20°C for long-term storage.
- Suitable for biochemical and cell-based assay applications.
Medchemexpress LLC HY-15508 5mg Medchemexpress, JANEX-1 CAS:202475-60-3 Purity:>98%
Medchemexpress, HY-15508 5mg JANEX-1 CAS:202475-60-3 JANEX-1 (WHI-P131) is a potent and specific JAK3 inhibitor (estimated Ki=2.3 μM). JANEX-1 (WHI-P131) shows potent JAK3-inhibitory activity (IC50 of 78 μM), does not inhibit JAK1 and JAK2. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC LY266097 hydrochloride | 172895-39-5 | 99.6% | 407.33 g/mol | C21H24Cl2N2O2 | 1 ML
A selective 5-HT2B receptor antagonist supplied as the hydrochloride salt for laboratory research applications. It is used in vitro and in vivo to study 5-HT2B-mediated signaling and neurotransmitter modulation. For research use only.
- High purity, 99.6%.
- Molecular weight 407.33 g/mol.
- Molecular formula C21H24Cl2N2O2.
- Available as 10 mM 1 mL solution in DMSO or as solid vials (5-100 mg).
- Recommended storage: sealed at -80°C up to 6 months or at -20°C up to 1 month.
Medchemexpress LLC Bepridil hydrochloride | 68099-86-5 | MFCD00065498 | 100.0% | 403.0 g/mol | C24H35ClN2O | 1 ML
Bepridil hydrochloride is the hydrochloride salt of bepridil, a non-selective calcium channel blocker used in research to probe cardiac ion channels and antianginal mechanisms. Supplied for research and analytical applications, it is available as a solid and as a prepared solution.
- Non-selective calcium channel blocker used in electrophysiology and pharmacology studies.
- Hydrochloride salt form enhances solubility for assays.
- Available as solid and as a 10 mM solution in DMSO for ready-to-use experiments.
- High purity (~99.98%) appropriate for analytical standards.
- Well-characterized identifiers: CAS 68099-86-5; molecular weight 403.0 g/mol.
Medchemexpress LLC Scopine hydrochloride | 85700-55-6 | 99.7% | 1 ML
Scopine hydrochloride, also known as 6,7-Epoxytropine hydrochloride, is a metabolite of Scopolamine and a brain-targeting compound. It significantly increases the brain exposure of Chlorambucil and enhances its anti-glioma activity. It can be utilized in targeted therapy research for brain gliomas.
- Metabolite of Scopolamine
- Brain-targeting compound
- Increases brain exposure of Chlorambucil
- Enhances anti-glioma activity
- Suitable for targeted therapy research for brain gliomas
eMolecules 56520-98-0 | 4-ETHYL-2-NITROPHENOL | MFCD16742721 | 1g
AstaTech | 4-ETHYL-2-NITROPHENOL | 1g | 268489544 | 36967 | 95.000 | 56520-98-0 | MFCD16742721 | 167.164 | C8H9NO3
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
Medchemexpress LLC Gr 127935 hydrochloride | 148642-42-6 | MFCD08056244 | 99.4% | 534.05 | C29H32ClN5O3 | 10 MG
GR127935 hydrochloride is a potent, orally active antagonist of 5-HT1D and 5-HT1B serotonin receptors used in neurological and pharmacological research. Supplied as a white to off-white solid, it is characterized by high purity and documented solubility and storage recommendations for reliable experimental use.
- High purity suitable for research applications.
- Potent 5-HT1D and 5-HT1B receptor antagonism for receptor pharmacology studies.
- Supplied in small milligram quantities for in vitro and in vivo dosing.
- Soluble in DMSO; follow recommended handling and storage.
- Documentation includes datasheet, certificate of analysis, and safety data sheet for traceability.
Medchemexpress LLC Sotorasib-d7 | 98.9% | 567.64 | 1 MG
Sotorasib-d7 (AMG-510-d7) is a deuterium-labeled Sotorasib. Sotorasib is a first-in-class, orally bioavailable, and selective KRAS G12C covalent inhibitor. It irreversibly inhibits KRAS G12C by locking it in an inactive GDP-bound state, leading to the regression of KRAS G12C-mutated locally advanced or metastatic non-small cell lung cancer (NSCLC).
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules for quantitation during the drug development process.
- Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC RS100329 hydrochloride | 1215654-26-4 | 99.6% | 462.89 g/mol | C20H26ClF3N4O3 | 25 MG
RS100329 hydrochloride is the hydrochloride salt of RS100329, a potent and selective α1A-adrenoceptor antagonist used in pharmacological research, including studies of urethral reflex contractions and benign prostatic hyperplasia. It is supplied as a solid research chemical with high reported purity and defined storage recommendations.
- Potent, selective α1A-adrenoceptor antagonist (pKi 9.6 for α1A).
- High purity (≈99.6% by HPLC), suitable for biochemical assays.
- Well-characterized small molecule: molecular weight 462.89 g/mol, formula C20H26ClF3N4O3.
- Provided as a solid hydrochloride salt for accurate dosing in experiments.
- Recommended storage: 4°C protected from light; in solvent, -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC PD153035 (hydrochloride) | 183322-45-4 | 99.5% | 10 MG
PD153035 Hydrochloride is a potent ATP-competitive epidermal growth factor receptor (EGFR) inhibitor used in biochemical and cellular research to block EGFR signaling with very high affinity.
- Potent EGFR inhibitor; Ki ≈ 6 pM, IC50 ≈ 25 pM.
- High reported purity of 99.5%.
- Molecular weight 396.67 g·mol⁻¹; chemical formula C16H15BrClN3O2.
- Available as a 10 mg solid and as 10 mM solutions in DMSO.
- Suitable for biochemical assays and cell signaling studies.
Medchemexpress LLC RS100329 hydrochloride | 1215654-26-4 | 99.6% | 462.89 g/mol | C20H26ClF3N4O3 | 100 MG
RS100329 hydrochloride is the hydrochloride salt of a potent and subtype-selective α1A-adrenoceptor antagonist used as a research reagent in receptor pharmacology and selectivity studies. The compound is supplied as a solid, with a reported molecular weight of 462.89 g/mol and high batch-specific purity; consult the certificate of analysis for exact values and handling instructions.
- Potent, selective α1A-adrenoceptor antagonist.
- Hydrochloride salt form for improved stability and handling.
- High purity suitable for in vitro pharmacology (COA available).
- Supplied as a solid for dissolution in common organic solvents.
- Used in receptor binding and functional assays to assess selectivity.
Medchemexpress LLC AC-099 hydrochloride | 849335-07-5 | C9H9C2F3N4 | 100 MG
AC-099 hydrochloride is a chemical substance provided as a solid, primarily intended for laboratory applications and the synthesis of various other substances.
- For research use only
- Suitable for experienced personnel
- Not fully validated for medical applications
Medchemexpress LLC Cyclohexanecarboxylic acid, 1-phenyl-, 2-(4-morpholinyl)ethyl ester, hydrochloride (1:1) | 75136-54-8 | 99.79% | 353.88 | 5 MG
PRE-084 hydrochloride is a highly selective σ1 receptor (S1R) agonist with an IC50 of 44 nM.
- Exhibits good neuroprotective effects.
- Can improve motor function and motor neuron survival in mice.
- Can ameliorate myocardial ischemia-reperfusion injury in rats by activating the Akt-eNOS pathway.
Medchemexpress LLC LDC4297 hydrochloride | 2319747-14-1 | 98.2% | 1 ML
LDC4297 hydrochloride is a selective inhibitor of CDK7 with an IC50 value of 0.13 nM. It inhibits human cytomegalovirus (HCMV) replication with an EC50 value of 24.5 nM. This product shows broad antiviral activities against Herpesviridae, Adenoviridae, Poxviridae, Retroviridae, and Orthomyxoviridae, with EC50 values ranging from 0.02-1.21 μM. It can be used for infection research.
- Dose-dependently inhibits HCMV replication with an EC50 of 24.5 nM
- Shows anti-proliferative activity in primary human fibroblast cultures with a GI50 of 4.5 μM
- Exhibits anti-HCMV activity by interfering with virus-induced Rb phosphorylation
- Demonstrates broad antiviral activities against various viruses including HCMV, GPCMV, MCMV, HIV-1, and Influenza A virus