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Filtered Search Results
Medchemexpress LLC Bromo-PEG2-C2-azide | 530151-56-5 | 98.7% | 1 G
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Bromo-PEG2-C2-azide is a versatile non-cleavable linker utilized in the synthesis of antibody-drug conjugates (ADCs) and as a PEG-based PROTAC linker for PROTAC synthesis. This click chemistry reagent contains an azide group, enabling its use in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne groups, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups.
- Non-cleavable ADC linker
- PEG-based PROTAC linker
- Contains an azide group for click chemistry
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Enables strain-promoted alkyne-azide cycloaddition (SPAAC)
- Useful in synthesis of antibody-drug conjugates (ADCs)
- Applicable in synthesis of PROTACs
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Medchemexpress LLC Eteplirsen sodium | 91.2% | 10306 | 1 MG
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Eteplirsen (AVI 4658) sodium is a synthetic antisense oligonucleotide that induces dystrophin production. It promotes exon 51 skipping in Duchenne muscular dystrophy patients and is used in Duchenne muscular dystrophy research.
- Induces dystrophin production.
- Promotes exon 51 skipping.
- Research use.
- High purity.
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Medchemexpress LLC Ditiocarb sodium | 148-18-5 | 99.7% | 100 G
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Ditiocarb sodium (Sodium diethyldithiocarbamate) is an orally active copper reagent. It exhibits various activities such as antioxidation, chelation, anti-tumor effects, immunomodulation, and anti-HIV properties. It is suitable for research in tumors, inflammatory, and immune-related diseases.
- Acts as an orally active copper reagent.
- Exhibits antioxidation and chelation properties.
- Demonstrates anti-tumor effects.
- Provides immunomodulation.
- Possesses anti-HIV properties.
- Useful for research in inflammation and immune-related diseases.
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Medchemexpress LLC Terephthalaldehyde | 623-27-8 | MFCD00006949 | 99.9% | 134.13 g/mol | C8H6O2 | 500g
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Terephthalaldehyde is a cross-linking agent Terephthalaldehyde can copolymerize with chitosan and acrylic acid to form hydrogels that selectively adsorb anionic dyes Terephthalaldehyde can be used as a drug intermediate to synthesize a series of novel benzothiazole and benzotriazolopyrimidinone heterocyclic compounds[1][2]
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Medchemexpress LLC Ceftezole sodium | 41136-22-5 | 1 ML
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Ceftezole sodium is a broad-spectrum cephem antibiotic that is effective against many species of gram-positive and gram-negative bacteria. It also acts as an alpha-glucosidase inhibitor with in vivo anti-diabetic activity.
- Broad-spectrum cephem antibiotic
- Effective against many species of gram-positive and gram-negative bacteria
- Acts as an alpha-glucosidase inhibitor
- Has in vivo anti-diabetic activity
- Purity of 98.75%
- White to off-white solid appearance
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Medchemexpress LLC Bis-mal-peg11 | 97.3% | C38H62N4O17 | 25 MG
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Bis-Mal-PEG11 is a PEG-based PROTAC linker that is utilized in the synthesis of PROTACs. PROTACs consist of two distinct ligands connected by a linker; one ligand targets an E3 ubiquitin ligase and the other targets a specific protein. PROTACs function by leveraging the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Leverages the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
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Medchemexpress LLC Exatecan Intermediate 6 | 143655-58-7 | 99.0% | 235.26 | 25 G
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Exatecan Intermediate 6 is an intermediate for synthesizing Exatecan (HY-13631), which is a DNA topoisomerase I inhibitor with an IC50 value of 2.2 μM (0.975 μg/mL) used in cancer research. Exatecan Intermediate 6 can also be used to synthesize Antibody-Drug Conjugates (ADCs).
- Intermediate of Exatecan
- Can be used to synthesize antibody-drug conjugates (ADCs)
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Medchemexpress LLC Daclatasvir dihydrochloride | 1009119-65-6 | MFCD25541736 | 99.7% | 811.80 g/mol | C40H52Cl2N8O6 | 10 MG
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Daclatasvir dihydrochloride is the dihydrochloride salt of daclatasvir provided as a high-purity analytical research standard for laboratory use. It functions as a potent hepatitis C virus NS5A inhibitor and is supplied with supporting documentation for analytical and safety compliance.
- High purity suitable for analytical and research use.
- Solid white to yellow form with defined physical properties.
- Available in small-scale and bulk quantities and in solution formats.
- Supplied with datasheet, certificate of analysis, and safety data sheet.
- Intended for laboratory research and analytical reference applications.
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Apexbio Technology LLC Adrenalone HCl 62-13-5 10mM (in 1mL DMSO)
Adrenalone hydrochloride (CAS 62-13-5) is a synthetic adrenergic agonist primarily targeting alpha-1 adrenergic receptors Through activation of these receptors Adrenalone induces vasoconstriction leading to reduced local blood flow This pharmacological property underpins its utility as a topical hemostatic agent in research settings where precise modulation of vascular tone is required Adrenalone is frequently employed to investigate adrenergic receptor signaling pathways and the physiological mechanisms underlying vascular constriction
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Medchemexpress LLC Aminophylline | 317-34-0 | 99.7% | 25 G
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Aminophylline is a competitive, non-selective phosphodiesterase (PDE) inhibitor and adenosine receptor antagonist. It offers pulmonary vasodilator and bronchodilator actions, aiding asthma research. This dihydrate, a 2:1 ratio compound of theophylline with ethylenediamine, is less potent and shorter-acting than theophylline. It treats airway obstruction in asthma or COPD and serves off-label as a reversal agent during nuclear stress testing.
- Competitive PDE inhibitor and adenosine receptor antagonist
- Exhibits pulmonary vasodilator and bronchodilator actions
- Useful for asthma research
- Composed of theophylline with ethylenediamine (2:1 ratio)
- Less potent and shorter-acting than theophylline
- Treats airway obstruction in asthma or COPD
- Used off-label for nuclear stress test reversal
- Increases heart rate and contractility
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Medchemexpress LLC Isobutyl 4-hydroxybenzoate | 4247-02-3 | MFCD00020167 | 98.9% | 194.23 g·mol⁻¹ | C11H14O3 | 25 G
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Isobutylparaben (isobutyl 4-hydroxybenzoate) is a research-grade paraben used as an antimicrobial preservative and biochemical reagent. It is supplied as a white to off-white solid with high purity for biological and analytical studies, including receptor activity and toxicology research.
- High purity: 98.9% (as supplied).
- Agonist of PXR, CAR, and PPAR for nuclear receptor studies.
- Broad-spectrum antimicrobial properties; used as a preservative model.
- Chemical identifiers: CAS 4247-02-3; formula C11H14O3; MW 194.23 g·mol⁻¹.
- Suitable for biochemical, analytical, and toxicology research applications.
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Medchemexpress LLC ADAMTS13 Human CHO 100ug | 100ug
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The ADAMTS13 protein a metalloproteinase has a metalloproteinase domain a disintegrin-like domain and a thrombospondin type 1 motif It cleaves von Willebrand Factor and defects in this gene cause thrombotic thrombocytopenic purpura Alternative splicing generates multiple transcript variants ADAMTS13 is broadly expressed in various tissues including the liver testis and 24 other tissues ADAMTS13 Protein Human (CHO His) is the recombinant human-derived ADAMTS13 expressed by CHO with C-10 His labeled tag The total length of ADAMTS13 Protein Human (CHO His) is 655 a a
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Medchemexpress LLC Adenosine, 8-bromo-, cyclic 3',5'-(hydrogen phosphate), sodium salt (1:1) | 76939-46-3 | MFCD00149373 | ≥98.0% | 430.08 | C10H10BrN5NaO6P | 10MM 1ML
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8-Bromo-cAMP sodium salt is a cell-permeable cyclic AMP analog used to activate cyclic AMP-dependent protein kinase (PKA) in cellular and biochemical research. It is supplied as a solid and as a 10 mM solution in dimethyl sulfoxide (DMSO) (1 mL). The material is provided with high purity (≥98% by HPLC) and is characterized by molecular weight 430.08 and formula C10H10BrN5NaO6P. For research use only.
- Cell-permeable cyclic AMP analog for intracellular studies.
- Activates cyclic AMP-dependent protein kinase (PKA).
- Available as solid or 10 mM solution in DMSO (1 mL).
- High purity: ≥98% (HPLC).
- Molecular weight 430.08 and formula C10H10BrN5NaO6P.
- Suitable for studies of cAMP/PKA signaling, apoptosis, and proliferation.
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Medchemexpress LLC Polydextrose | 68424-04-4 | 95.3% | C12H22O11 | 100 G
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Polydextrose is a water-soluble oligosaccharide polymer used as an orally active prebiotic in research settings. It is supplied as a powder with reported purity around 95% and is used to study gut microbiota, lipid and glucose metabolism, and nutritional formulations. Intended for laboratory research use only, it enables investigation of dietary fiber effects in vitro and in vivo models.
- Water-soluble powder suitable for formulation and dosing.
- Functions as a prebiotic to support gut microbiota studies.
- Used in research on cholesterol and blood glucose modulation.
- Polymeric composition represents variable chain lengths for fiber studies.
- Available in multiple pack sizes for lab-scale experiments.
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Medchemexpress LLC N-[4-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]phenyl]-1-(2-furanylmethyl)-5-oxo-pyrrolidinecarboxamide | 2784577-71-3 | MFCD00701047 | C24H19ClN4O4 | 1 ML
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RLX-33 is a potent, selective, and blood-brain barrier (BBB) penetrant relaxin family peptide 3 (RXFP3) antagonist. This compound blocks relaxin-3-induced ERK1/2 phosphorylation and can prevent the stimulation of food intake induced by the RXFP3-selective agonist R3/I5 in rats, making it suitable for metabolic syndrome research.
- Potent and selective RXFP3 antagonist
- Blood-brain barrier penetrant
- Blocks relaxin-3-induced ERK1/2 phosphorylation
- Attenuates R3/I5-induced feeding
- Good brain penetration
- Highly protein-bound in rat plasma
- Useful for metabolic syndrome research
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