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Filtered Search Results
Medchemexpress LLC Thymine | 65-71-4 | >99.9% | 126.11 | 25 G
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Thymine is one of the four essential nucleobases found in DNA, playing a crucial role in genetic information storage. It serves as a substrate for rat liver dihydropyrimidine dehydrogenase (DPD), an enzyme involved in pyrimidine metabolism. This compound is intended for research use only and is available as a solid, white to off-white powder.
- Essential nucleobase of DNA
- Substrate for rat liver dihydropyrimidine dehydrogenase (DPD)
- High purity compound for reliable research
- Available as a solid, white to off-white powder
- Soluble in various solvents including DMSO and water
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Medchemexpress LLC Zika virus E (envelope) protein | 10 UG
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Recombinant Zika virus envelope (E) protein fragment produced in HEK293 cells with a C-terminal His tag. Supplied as a 0.22 μm filtered PBS solution (pH 7.4), this reagent is intended for research applications such as antigenicity studies, ELISA, and antibody characterization. Store frozen at -80°C and avoid repeated freeze-thaw cycles.
- Produced in HEK293 cells (human expression system).
- C-terminal His tag for detection or affinity purification.
- Supplied as a 0.22 μm filtered PBS solution, pH 7.4.
- Approximate molecular weight 13 kDa.
- Sequence corresponds to V593-K699 (accession ALU33341.1).
- For research use only; not for diagnostic or therapeutic use.
- Recommended long-term storage at -80°C; minimize freeze-thaw cycles.
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![eMolecules 166330-10-5 | Bis[(2-diphenylphosphino)phenyl] ether | Chem-Impex | MFCD00233863 | 538.567 | C36H28OP2 | 98.000 | O(c1ccccc1P(c1ccccc1)c1ccccc1)c1ccccc1P(c1ccccc1)c1ccccc1 | 25g | 603112932](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000223853.jpg-250.jpg)
eMolecules 166330-10-5 | Bis[(2-diphenylphosphino)phenyl] ether | Chem-Impex | MFCD00233863 | 538.567 | C36H28OP2 | 98.000 | O(c1ccccc1P(c1ccccc1)c1ccccc1)c1ccccc1P(c1ccccc1)c1ccccc1 | 25g | 603112932
Bis[(2-diphenylphosphino)phenyl] ether | Chem-Impex | 166330-10-5 | MFCD00233863 | 538.567 | C36H28OP2 | 98.000 | O(c1ccccc1P(c1ccccc1)c1ccccc1)c1ccccc1P(c1ccccc1)c1ccccc1 | 25g | 603112932
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Medchemexpress LLC H-Phg-OtBu.HCl | 161879-12-5 | 243.73 | 25 G
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H-Phg-OtBu.HCl, also known as Benzeneacetic acid, α-amino-, 1,1-dimethylethyl ester, hydrochloride (1:1), (αS)-, is a high-purity glycine derivative. This white to off-white solid is suitable for various research applications and has been referenced in studies investigating the effects of amino acid derivatives on physical, mental, and physiological activities.
- White to off-white solid
- High purity (99.3% by HPLC)
- Glycine derivative
- Referenced in amino acid derivative research
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Medchemexpress LLC Silver diethyldithiocarbamate | 1470-61-7 | MFCD00004929 | 99.2% | 256.14 g·mol⁻¹ | C5H10AgNS2 | 25 G
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Silver diethyldithiocarbamate is a silver salt of the diethyldithiocarbamate ligand used as a chelating reagent in analytical chemistry to form stable complexes with metal ions for spectroscopic analysis. It is supplied as a solid with high stated purity and is suitable for laboratory use in metal detection and related assays.
- Used as a reagent and chelating agent for metal ion detection.
- High purity suitable for UV-Vis spectroscopy and analytical work.
- Light yellow to light brown solid appearance.
- Molecular weight 256.14 g·mol⁻¹; formula C5H10AgNS2.
- Provided in 25 g packaging for laboratory-scale use.
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Medchemexpress LLC XP-524 | 2344825-52-9 | 98.0% | 552.65 | 50 MG
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XP-524 is a potent BET and EP300 inhibitor that has shown significant tumoricidal activity in vivo, preventing KRAS-induced neoplastic transformation and prolonging survival in aggressive pancreatic ductal adenocarcinoma (PDAC) models. It also enhances self-peptide presentation and tumor recruitment of cytotoxic T lymphocytes, making it a promising candidate for PDAC research.
- Potent BET and EP300 inhibitor
- Exhibits tumoricidal activity in vivo
- Prevents KRAS-induced neoplastic transformation
- Prolongs survival in pancreatic ductal adenocarcinoma models
- Enhances presentation of self-peptide
- Improves tumor recruitment of cytotoxic T lymphocytes
- Suitable for research into pancreatic ductal adenocarcinoma
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Medchemexpress LLC Ethylenediaminetetra 100g
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Ethylenediaminetetraacetic acid (EDTA) sodium hydrate is a kind of metal chelating agent (binds to bivalent and trivalent metal cations including calcium) Ethylenediaminetetraacetic acid sodium hydrate has antibacterial anti-inflammatory antioxidant anti-hypercalcemia and anticoagulant activities Ethylenediaminetetraacetic acid sodium hydrate decreases the metal ion-catalyzed oxidative damage to proteins and allows maintenance of reducing environment during protein purification Ethylenediaminetetraacetic acid sodium hydrate can alleviate the liver fibrosis Ethylenediaminetetraacetic acid sodium hydrate can be used for coronary artery disease and neural system disease research[1][2][3][4][5][6][7]
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Medchemexpress LLC Anticancer agent 129 | 135882-37-0 | 99.01% | 275.35 | 25 MG
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Anticancer agent 129 (Compound 3a) is a quinoline derivative predicted to have anti-cancer activity. It is intended for research use only and not sold to patients.
- High purity for reliable research results
- Available in various quantities to suit experimental needs
- Detailed documentation available including data sheet, COA, and SDS
- Suitable for research in cancer disease areas
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Medchemexpress LLC Phospho-RSK1 p90 (Ser380) Antibody (YA158) | 100 UL
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Phospho-RSK1 p90 (Ser380) Antibody (YA158) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting Phospho-RSK1 p90 (Ser380). It is intended for research use only.
- Rabbit host
- Recombinant, monoclonal clonality
- Observed molecular weight of 90 kDa
- Human, rat, mouse species reactivity
- Affinity purified
- Non-conjugated
- Supplied in liquid form
- Stored at -20°C for 1 year
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Medchemexpress LLC 2-(Dimethylphosphoryl)benzenamine | 1197953-47-1 | 169.16 | 100 G
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2-(DiMethylphosphoryl)benzenamine is a chemical compound primarily used as a drug intermediate for the synthesis of various active pharmaceutical ingredients. It serves as a crucial building block in medicinal chemistry.
- High purity, ensuring reliable results in synthesis.
- Versatile intermediate for drug discovery.
- Available in quantities suitable for research and development.
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Medchemexpress LLC Ferroptosis-IN-21 (8-hydroxy-1,2,3,4-tetrahydroquinoline) | 6640-50-2 | 149.19 | 25 G
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Ferroptosis-IN-21 is a ferroptosis inhibitor that protects against renal ischemia/reperfusion (I/R) injury. It acts by suppressing ferroptosis and directly scavenging peroxyl radicals, exhibiting broad-spectrum anti-ferroptotic efficacy and nanomolar potency in renal tubular epithelial cells.
- Exhibits nanomolar cytoprotective activity (EC50 = 61.7 nM) and reverses cell death
- Protects human kidney cells from induced ferroptosis
- Suppresses lipid Reactive Oxygen Species accumulation
- Demonstrates potent direct radical scavenging activity
- Ameliorates renal I/R injury in mice
- Reduces serum creatinine and blood urea nitrogen in I/R models
- Decreases lipid peroxidation biomarkers
- Useful for ferroptosis-targeted drug development research
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Medchemexpress LLC OARV-771 | 2683008-37-7 | 98.8% | C49H59ClN8O8S2 | 25 MG
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OARV-771 is a VHL-based BET degrader (PROTAC) with improved cell permeability. It shows DC50s of 6 nM for Brd4, 1 nM for Brd2, and 4 nM for Brd3. It also exhibits an antiproliferative effect with an EC50 value of 4 nM in MV4;11 cells.
- VHL-based BET degrader (PROTAC)
- Enhanced cell permeability
- Demonstrates DC50s of 6 nM for Brd4, 1 nM for Brd2, and 4 nM for Brd3
- Exhibits an antiproliferative effect with an EC50 value of 4 nM in MV4;11 cells
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Medchemexpress LLC Polyethylene glycol 200 | 25322-68-3 | MFCD00081839 | 98.0% | 200.00 | (C2H4O)nH2O | 100g
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PEG200 (Polyethylene glycol 200) a neutral polymer of molecular weight 200 is a water-soluble low immunogenic and biocompatible polymer formed by repeating units of ethylene glycol[1]
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![Alkali Scientific DTT [DL Dithiothreitol] (Cleland's Reagent)], 10 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000660945.jpg-250.jpg)
Alkali Scientific DTT [DL Dithiothreitol] (Cleland's Reagent)], 10 G
Dithiothreitol (DTT), also known as Cleland's Reagent, is a highly effective reducing agent used in protein stabilization and enzyme assays. This 10g reagent is utilized in laboratory applications that require the reduction of disulfide bonds to prevent oxidation and preserve protein function. DTT is essential in maintaining the integrity of proteins during purification, electrophoresis, and structural studies. It is also used in cellular assays to protect proteins from oxidative damage and facilitate accurate enzyme activity measurements. DTT is an indispensable tool in molecular biology, biochemistry, and pharmaceutical research where maintaining protein structure and function is crucial.
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Apexbio Technology LLC Ozagrel HCl 78712-43-3 10mM (in 1mL DMSO)
Ozagrel hydrochloride (CAS 78712-43-3) is a small molecule inhibitor of thromboxane A2 (TXA2) synthase modulating platelet activity by suppressing TXA2 production In experimental models Ozagrel hydrochloride selectively inhibits TXA2-mediated human platelet aggregation exhibiting an IC50 of approximately 53 12 M This compound is employed in platelet-related assays to investigate the role of TXA2 signaling in coagulation thrombosis and cardiovascular pathophysiology
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