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Filtered Search Results
Apexbio Technology LLC Buspirone HCl 33386-08-2 10mM (in 1mL DMSO)
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Buspirone hydrochloride (CAS 33386-08-2) is a selective agonist of the 5-HT1A serotonin receptor subtype engaging central nervous system sites to modulate serotonergic neurotransmission Through its specific interaction with 5-HT1A receptors buspirone hydrochloride influences neurochemical signaling pathways associated with anxiety and mood regulation This compound is widely utilized as a research tool in studies investigating the neurobiological mechanisms underlying anxiety and depression as well as the interplay between central neurotransmitter systems and emotional processing
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Apexbio Technology LLC Chlorhexidine HCl 3697-42-5 10mM (in 1mL DMSO)
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Chlorhexidine HCl (CAS 3697-42-5) is an antiseptic agent designed to interact with microbial cell membranes thereby increasing membrane permeability and disrupting membrane integrity Chlorhexidine HCl exerts its biological activity primarily through binding to negatively charged surfaces of bacterial membranes resulting in leakage of cellular contents and consequent microbial cell death In microbiological assays chlorhexidine HCl demonstrates broad-spectrum antimicrobial activity with reported IC50 values against various microbial strains generally in the micromolar concentration range though specific values depend on the target organism and experimental conditions Based on these pharmacological properties chlorhexidine HCl holds research potential in antimicrobial susceptibility testing and as a control compound in comparative studies of novel antimicrobial agents
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000452058 3-CHLOROIMINODIBENZY 50G
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![Medchemexpress LLC N'-[3-[[5-bromo-2-[3-(pyrrolidine-1-carbonylamino)anilino]pyrimidin-4-yl]amino]propyl]-2,2-dimethylpropanediamide | 702676-93-5 | MFCD12922516 | 99.4% | 547.45 g·mol⁻1 | C23H31BrN8O3 | 1 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000243934.png-250.jpg)
Medchemexpress LLC N'-[3-[[5-bromo-2-[3-(pyrrolidine-1-carbonylamino)anilino]pyrimidin-4-yl]amino]propyl]-2,2-dimethylpropanediamide | 702676-93-5 | MFCD12922516 | 99.4% | 547.45 g·mol⁻1 | C23H31BrN8O3 | 1 MG
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BX-320 is a selective, ATP-competitive, orally active small-molecule inhibitor of PDK1 for preclinical research. It inhibits PDK1 with an IC50 of 30 nM, blocks PDK1/Akt signaling, induces apoptosis in tumor cells, and has demonstrated antiproliferative and antitumor activity in cell-based and animal models.
- Selective ATP-competitive PDK1 inhibitor (IC50 30 nM).
- Blocks PDK1/Akt signaling and induces apoptosis in tumor cells.
- Demonstrates antiproliferative activity in cell assays and efficacy in in vivo tumor models.
- Exhibits off-target activity against Chk1, c-Kit, KDR, PKA, CDK2, GSK3β, and PKC at micromolar concentrations.
- High purity (99.4%).
- Molecular weight 547.45 g·mol⁻1; formula C23H31BrN8O3.
- Store solid at -20°C; in solvent store at -80°C (up to 6 months) or -20°C (up to 1 month).
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000453826 BENZYLDIMETHYLTETRAD 25G
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Medchemexpress LLC Samuraciclib hydroch 25mg | 1805789-54-1 | 25MG
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Samuraciclib hydrochloride (CT7001 hydrochloride) is a potent selective ATP-competitive and orally active CDK7 inhibitor with an IC50 of 41 nM Samuraciclib hydrochloride displays 45- 15- 230- and 30-fold selectivity over CDK1 CDK2 (IC50 of 578 nM) CDK5 and CDK9 respectively Samuraciclib hydrochloride inhibits the growth of breast cancer cell lines with GI50 values between 0 2-0 3 M Samuraciclib hydrochloride has anti-tumor effects[1 [2
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000377808 RAVOXERTINIB HYDROCH 50MG
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Medchemexpress LLC Alvespimycin hydrochloride | 467214-21-7 | 98.8% | 5 MG
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Alvespimycin hydrochloride is a small-molecule Hsp90 inhibitor used for biochemical and cell-based research. It is supplied as the hydrochloride salt to improve solubility and has reported activity at low nanomolar concentrations.
- Potent Hsp90 inhibitor; EC50 62 ± 29 nM.
- Hydrochloride salt for enhanced solubility.
- Molecular weight 653.21 g/mol; formula C32H49ClN4O8.
- Available in small pack sizes suitable for research-scale use.
- Purity reported as 98.8% (HPLC).
- Suitable for biochemical and cell-based assays.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000380807 AS-252424 10MM 1ML
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Medchemexpress LLC KLOTHO HUMAN CHO 5UG
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5000177349 KLOTHO HUMAN CHO 5UG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000388922 POTASSIUM SORBATE 100G
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Medchemexpress LLC TTA-P2 | 1072018-68-8 | 99.6% | 431.37 g/mol | C21H29Cl2FN2O2 | 1 MG
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TTA-P2 is a research-grade small-molecule inhibitor of T-type (Cav3) calcium channels. It is selective, orally active, and blood-brain barrier permeant, with reported potency (IC50 ≈ 22 nM). Common applications include electrophysiology, studies of neuronal excitability, and in vivo pain and epilepsy models.
- Selective T-type calcium channel blocker with nanomolar potency.
- Orally active and blood-brain barrier permeant.
- Suitable for electrophysiology and in vivo neurological models.
- Well characterized in pain and epilepsy research literature.
- Supplied in solid form and in ready-to-use DMSO solution formats.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000448026 ACETYLPYRAZINE 25G
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Medchemexpress LLC GM-CSF Rhesus macaq 5ug
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Recombinant GM-CSF protein from rhesus macaque supplied lyophilized for research use. The protein is expressed in E. coli, shows >95% purity by reducing SDS-PAGE, and has a predicted molecular mass of approximately 14.4 kDa. The provided sequence corresponds to residues A18-E144. Follow the recommended storage and reconstitution instructions to maintain activity and stability.
- Recombinant protein expressed in E. coli.
- Greater than 95% purity by reducing SDS-PAGE.
- Predicted molecular mass ~14.4 kDa.
- Sequence corresponds to A18-E144 of the mature protein.
- Lyophilized formulation with buffered and trehalose options for stability.
- Store at -20°C; reconstitute at ≥100 μg/mL and aliquot for long-term storage.
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Apexbio Technology LLC HyperTrap Q FF Column 5ml
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The HyperTrap Q FF Column is not a small molecule but a chromatography medium designed for the purification of biomolecules particularly proteins and nucleic acids It operates via strong anion exchange chromatography utilizing quaternary ammonium functional groups immobilized on a Fast Flow resin matrix to selectively bind negatively charged molecules under defined buffer conditions This allows for efficient separation and recovery of target biomolecules from complex mixtures The HyperTrap Q FF Column is applied in research settings for desalting buffer exchange and isolation of nucleic acids or proteins supporting downstream analyses and preparative workflows in the biomedical field
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