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Filtered Search Results
eMolecules DOLUTEGRAVIR SODIUM 5G
5000188547 DOLUTEGRAVIR SODIUM 5G
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eMolecules CYCLOPENT-3-ENAMINE HYDROCH 5G
5000188582 CYCLOPENT-3-ENAMINE HYDROCH 5G
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Medchemexpress LLC L-pyrohomoglutamic acid | 34622-39-4 | MFCD03839863 | 97.0% | 143.14 g·mol⁻¹ | C6H9NO3 | 5 G
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L-pyrohomoglutamic acid is a non-proteinogenic amino acid used as a synthetic building block in medicinal chemistry and biochemical research. It is employed as an intermediate for preparing ligands targeting FK506-binding proteins (FKBPs) and histone deacetylase (HDAC) inhibitors, and is supplied as a purified powder for laboratory use.
- High purity (~97%) suitable for research applications.
- Used as a building block for FKBP and HDAC ligand synthesis.
- Molecular formula C6H9NO3 and molecular weight 143.14 g·mol⁻¹.
- Available in lab-scale pack sizes for synthetic and analytical workflows.
- Provided with product documentation including COA and SDS for quality assurance.
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Medchemexpress LLC hsa-miR-21-5p mimic 20nmol | 20nmol
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hsa-miR-21-5p mimics are small chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity
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eMolecules 2-CHLORO-3-HYDRAZINYLPYRAZ 10G
5000188387 2-CHLORO-3-HYDRAZINYLPYRAZ 10G
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Medchemexpress LLC S R S-AHPC-C4-NH2 hy 2g | 2245697-83-8 | 2 G
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(S,R,S)-AHPC-C4-NH2 hydrochloride is an E3 ligase VHL ligand-linker conjugate supplied as a hydrochloride salt and used as a building block for PROTAC synthesis, particularly for VHL-based and EED-targeted degraders. It is provided in solid form or as ready-to-use DMSO solutions to support conjugation, screening, and medicinal chemistry workflows.
- E3 ligase VHL ligand-linker conjugate suitable for PROTAC design.
- Hydrochloride salt supplied as a solid with light yellow to green yellow color.
- Available as solid and as 10 mM DMSO solution for ready reconstitution.
- Intended as a synthetic building block for degrader molecules.
- Documented purity and supporting datasheet and SDS available.
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Cell Signaling Technology CELL SIGNALING TECHNOLOGY INC
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5000587628 F4/80 F7U5M RABBIT MONOCLONAL
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Cell Signaling Technology CELL SIGNALING TECHNOLOGY INC
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5000587810 REPTIN/RUVBL2 D8N3J RABBIT MON
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Medchemexpress LLC SKF-83566 | 99295-33-7 | 99.8% | 332.23 | C17H18BrNO | 5 MG
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SKF-83566 is a potent, blood-brain permeable, and orally active D1-like dopamine receptor antagonist (CAS 99295-33-7) used in pharmacological research. It also displays weaker competitive antagonism at 5-HT2 receptors, inhibits dopamine transporter activity in some assays, and can selectively inhibit adenylyl cyclase 2.
- Potent D1-like dopamine receptor antagonist suitable for receptor pharmacology studies.
- Blood-brain permeable and orally active in preclinical models.
- High purity solid (~99.8%) for consistent experimental results.
- Soluble in DMSO at approximately 33.33 mg/mL; ultrasonication may be required.
- Stable when stored as a powder at -20°C for long-term storage.
- Commonly used in Parkinson's disease and nicotine craving research.
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Medchemexpress LLC I2959 photoinitiator | 106797-53-9 | 98.67% | 224.26 | 100 G
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I2959 is a photoinitiator widely used for the photochemical cross-linking of hydrogels. Its combination with CMA hydrogel has been utilized as a bio-ink in biological 3D printing applications. This product exhibits high free radical generation efficiency and is cytotoxic to rapidly dividing cell lines.
- Used as a photoinitiator in photochemical cross-linking of hydrogels.
- Applied as a bio-ink for biological 3D printing when combined with CMA hydrogel.
- Generates free radicals efficiently.
- Cytotoxic to rapidly dividing cell lines.
- Suitable for in vitro encapsulation of Saos-2 cells in photochemically cross-linked CMA hydrogels.
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Medchemexpress LLC Foscarnet trisodium hexahydrate | 34156-56-4 | 99.5% | 300.04 | 10 G
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Foscarnet trisodium hexahydrate is an inhibitor of viral DNA polymerase activity, which leads to reversible suppression of viral replication. It is an antiherpesvirus agent used in cytomegalovirus retinitis.
- Viral DNA polymerase activity inhibitor
- Leads to reversible suppression of viral replication
- Antiherpesvirus agent
- Used in cytomegalovirus retinitis
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Medchemexpress LLC 3-hydroxy-1,2,3-benzotriazin-4(3H)-one | 28230-32-2 | MFCD00042803 | 99.9% | 163.13 g/mol | C7H5N3O2 | 100g
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HODHBt (HOOBt) inhibits STAT5-SUMO interaction by blocking SUMOylation of phosphorylated STAT5 HODHBt enhances the magnitude of IL-15 signaling and significantly increases the natural killer (NK) cell cytotoxicity phenotype and function and the generation of cytokine-induced memory-like (CIML) natural killer (NK) cells HODHBt can be used for research of HIV-infection and cancer[1]
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Medchemexpress LLC dUTP trisodium | 102814-08-4 | MFCD00084701 | 99.7% | 534.09 g·mol⁻¹ | C9H12N2Na3O14P3 | 100 MG
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dUTP trisodium is the trisodium salt of 2'-deoxyuridine-5'-triphosphate, used in molecular biology as a uracil-containing nucleotide substitute for dTTP. It is provided as a high-purity solid and as a PCR-grade solution for incorporation into PCR and enzymatic assays; intended for research use only (not for human use).
- High purity (>99% by HPLC) ensuring reliable incorporation.
- Available as a solid (100 mg) and as a 100 mM PCR-grade solution.
- Suitable for PCR and RT-PCR applications as a dTTP substitute.
- Stable when stored per manufacturer guidance; supports long-term storage in solution at -80°C.
- Supplied with certificate of analysis reporting assay and storage recommendations.
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Cell Signaling Technology CELL SIGNALING TECHNOLOGY INC
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5000587519 P5CS/ALDH18A1 F2I9F RABBIT MON
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Medchemexpress LLC GM-60186 | 99.3% | 504.59 | 1 ML
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GM-60186 is a 5-HT receptor 2B (HTR2B) inhibitor with an IC50 of 257 nM. It significantly inhibits colorectal cancer proliferation and migration.
- Inhibits HTR2B with an IC50 of 257 nM.
- Demonstrates anti-colorectal cancer activity.
- In vitro, it effectively inhibits proliferation in colorectal cancer (CRC) cells (COLO-205, MC38, CT26, and Caco2 cells) at concentrations of 50-500 nM over 72 hours.
- Effectively inhibits colorectal cancer migration at 500 nM over 24-48 hours.
- In vivo, it significantly reduces tumor size and weight in xenograft mouse models at doses of 10-20 mg/kg, administered daily for 20 days.
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