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Filtered Search Results
Aobchem AOBCHEM
5000864707 4-BROMO-1-ISOPROPOXY-2-METHOXY
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5000864712 1-BROMO-3- 2-METHYLPROPOXY BEN
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5000864875 3-BROMO-2 6-DIFLUOROPHENOL 5G
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Apexbio Technology LLC Propafenone HCl 34183-22-7 10mM (in 1mL DMSO)
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Propafenone hydrochloride (CAS 34183-22-7) is a synthetic small molecule classified as a Class Ic antiarrhythmic agent It acts by inhibiting fast inward sodium currents in cardiac myocytes resulting in slowed conduction and stabilization of cardiac electrical activity Through this sodium channel blockade Propafenone hydrochloride is utilized in biomedical research to investigate the electrophysiological properties of myocardial tissue and to model atrial and ventricular arrhythmias Its application aids in elucidating the molecular mechanisms underlying abnormal cardiac rhythms and supports the development of therapeutic interventions for tachyarrhythmic conditions
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Apexbio Technology LLC TA 01 1784751-18-3 10mM (in 1mL DMSO)
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TA 01 (CAS 1784751-18-3) is a small molecule inhibitor that targets casein kinase 1 isoforms CK1 and CK1 as well as p38 MAPK It exhibits potent inhibitory activity with IC50 values of approximately 6 4 nM for CK1 6 8 nM for CK1 and 6 7 nM for p38 MAPK Through these actions TA 01 is utilized to investigate cellular signal transduction pathways and regulatory mechanisms of circadian rhythm It is particularly applicable in studies focused on pathophysiological processes associated with CK1 and p38 MAPK signaling including those related to cardiac signaling networks
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Aobchem AOBCHEM
5000864540 3-BROMO-2-METHYLPHENYLBORONIC
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Medchemexpress LLC 2-Hydroxyestrone-d4 | 81586-97-2 | 97.9% | 290.39 | 1 MG
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2-Hydroxyestrone-d4 is the deuterium-labeled form of 2-Hydroxyestrone. 2-Hydroxyestrone (Catecholestrone) acts as a specific receptor-mediated antiestrogenic agent and is recognized for its anticarcinogenic properties.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process.
- Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
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Medchemexpress LLC Ifebemtinib (hydrochloride) | 1227948-82-4 | 99.2% | 625.01 | 10 MM/1 ML
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Ifebemtinib is an orally bioavailable inhibitor of the non-receptor, cytoplasmic tyrosine kinase protein tyrosine kinase 2 (FAK: PTK2) with potential antineoplastic activity. It targets and inhibits PTK2 in an adenosine triphosphate (ATP)-competitive manner, preventing PTK2-mediated downstream signaling and inhibiting migration, proliferation, invasion, and survival in PTK2-overexpressing tumor cells.
- Orally bioavailable inhibitor of FAK1/PTK2
- Targets and inhibits PTK2 in an ATP-competitive manner
- Prevents PTK2-mediated downstream signaling
- Inhibits migration, proliferation, invasion, and survival in PTK2-overexpressing tumor cells
- Stable under recommended storage conditions
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Medchemexpress LLC Ifebemtinib (hydrochloride) | 1227948-82-4 | 99.2% | 625.01 | 100 MG
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Ifebemtinib hydrochloride is a potent and orally active FAK inhibitor. It is extensively researched for its role in inhibiting cancer progression.
- Inhibits focal adhesion kinase (FAK) activity.
- Demonstrates high potency with an IC50 of 1 nM for recombinant FAK.
- Orally active, making it suitable for in vivo studies.
- Potential for use in anticancer research.
- Acts as an ATP-competitive inhibitor.
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Medchemexpress LLC Oblimersen sodium | 98.09% | 5684.61 (free acid) | 1 MG
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Oblimersen sodium functions as a BCL-2 inhibitor by targeting BCL-2 RNA. It specifically binds to the first six codons of the bcl-2 mRNA sequence, leading to the degradation of bcl-2 mRNA and inducing apoptosis by down-regulating the expression of Bcl-2. Oblimersen sodium can be used for cancer research.
- Functions as a BCL-2 inhibitor
- Targets BCL-2 RNA
- Binds to the first six codons of bcl-2 mRNA sequence
- Leads to degradation of bcl-2 mRNA
- Induces apoptosis by down-regulating Bcl-2 expression
- Suitable for cancer research
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Medchemexpress LLC 3-MeOARh-NTR | 98.1% | 596.61 | 25 MG
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3-MeOARh-NTR is an activatable imaging probe known for its high selectivity and good stability. It offers a high signal-to-noise ratio for nitroreductase (NTR) detection, making it an efficient molecular tool for sensing endogenous NTR. This probe is capable of producing a strong fluorescence signal in living HeLa cells under decreasing oxygen conditions and can facilitate fluorescence imaging of kidney tissues in mice, serving as an effective tool to evaluate kidney hypoxia.
- High selectivity and good stability
- High signal-to-noise ratio for nitroreductase (NTR) detection
- Efficient molecular tool for endogenous NTR detection
- Produces strong fluorescence signal in living HeLa cells with decreasing oxygen contents
- Efficient probe to evaluate kidney hypoxia by NTR detection
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Sigma Organic Chemistry Oil of turpentine | 2L | 8006-64-2 | MFCD00147790
CAS #: 8006-64-2
MDL #: MFCD00147790
UNSPSC Code: 12352103
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Medchemexpress LLC Isovanillin | 621-59-0 | 99.99% | 152.15 | 500 G
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Isovanillin is identified as an aldehyde oxidase inhibitor and exhibits antispasmodic and antidiarrheal activities. It is not a substrate for aldehyde oxidase and is metabolized to isovanillic acid primarily by aldehyde dehydrogenase.
- Acts as an aldehyde oxidase inhibitor.
- Demonstrates relaxant effects on ileum contractions induced by 5-HT.
- Has antidiarrheal and anti-motility effects on the gastrointestinal tract.
- Potentially useful for research involving aldehyde oxidase inhibition.
- Offers a compound with known antispasmodic properties for relevant pharmacological studies.
- Provides a substance with documented antidiarrheal effects, suitable for gastrointestinal research.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000701322 DUOCARMYCIN SA 1MG
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![Alkali Scientific Kinetin [6 Furfurylaminopurine], 1 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000659895.jpg-250.jpg)
Alkali Scientific Kinetin [6 Furfurylaminopurine], 1 G
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Kinetin (6-Furfurylaminopurine) is a cytokinin widely used in plant tissue culture to promote cell division, shoot initiation, and overall plant growth. This 1g formulation is particularly effective in stimulating the development of lateral shoots and enhancing plant regeneration from cultured tissues. Kinetin plays a crucial role in delaying senescence and can influence the differentiation of plant cells into specific tissues. Its application is essential in tissue culture systems where rapid plant regeneration or vegetative propagation is required. Kinetin is also used in biotechnology for enhancing crop yields and improving resistance to stress by influencing plant growth patterns and metabolic pathways.
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