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Filtered Search Results
Apexbio Technology LLC HyperTrap SP HP Column 1ml
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HyperTrap SP HP Column is a chromatography medium designed for the efficient purification of biomolecules based on strong cation exchange principles The column utilizes sulfopropyl (SP) ligands immobilized on a high-performance matrix allowing selective binding of positively charged proteins and peptides under controlled buffer conditions This mechanism facilitates the separation and enrichment of target analytes from complex biological samples The HyperTrap SP HP Column is commonly applied in protein purification workflows biomarker discovery and quality control assays within biomedical research
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000383135 NECROSTATIN-34 10MM 1ML
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eMolecules TRIFLUOROMETHYLTRIMETHYLS 250G
5000223712 TRIFLUOROMETHYLTRIMETHYLS 250G
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Apexbio Technology LLC Tolazoline HCl 59-97-2 10mM (in 1mL DMSO)
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Tolazoline hydrochloride (CAS 59-97-2) is a small molecule that functions as a competitive antagonist at -adrenergic receptors exhibiting non-selective affinity for both 1- and 2-adrenoceptor subtypes By inhibiting endogenous catecholamine binding tolazoline modulates vasomotor tone and vascular smooth muscle contraction This pharmacological profile enables researchers to investigate adrenergic signaling pathways and the physiological roles of -adrenergic receptors Tolazoline HCl is widely utilized in studies of vascular function receptor pharmacology and the characterization of sympathetic nervous system mechanisms
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Medchemexpress LLC Pf-07038124 hydrochloride | 2415317-57-4 | 99.3% | 363.64 g/mol | C18H23BClNO4 | 5 MG
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PF-07038124 hydrochloride is the hydrochloride salt of a selective phosphodiesterase 4 (PDE4) inhibitor supplied for laboratory research into inflammatory skin diseases and immune signaling pathways. Intended for research use only; not for human or clinical use.
- High purity suitable for biochemical and cellular assays.
- Potent inhibition of PDE4B2 (IC50 ≈ 0.5 nM).
- Demonstrated cytokine inhibition of IL-13, IL-4, and IFN-γ in reported assays.
- Available in small milligram quantities for early-stage studies.
- Hydrochloride salt form improves solubility for aqueous assays.
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Apexbio Technology LLC LX-1031 945976-76-1 10mM (in 1mL DMSO)
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LX-1031 (CAS 945976-76-1) is an orally administered small-molecule inhibitor of tryptophan hydroxylase (TPH) the rate-limiting enzyme in peripheral serotonin (5-HT) biosynthesis As a heterocyclic phenylalanine analogue LX-1031 selectively reduces 5-HT synthesis outside the central nervous system In vitro LX-1031 suppresses TPH1 activity within nanomolar concentration ranges In animal studies oral administration leads to dose-dependent reductions in jejunal 5-HT levels Clinical investigations have demonstrated that LX-1031 lowers urinary 5-hydroxyindoleacetic acid (5-HIAA) reflecting decreased peripheral serotonin turnover LX-1031 is under investigation for disorders characterized by elevated peripheral 5-HT such as diarrhea-predominant irritable bowel syndrome
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Medchemexpress LLC Cvt-313 (cdk2 inhibitor iii) | 199986-75-9 | C20H28N6O3 | 100 MG
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CVT-313 (Cdk2 Inhibitor III) is a potent, selective, reversible, and ATP-competitive inhibitor of CDK2 with an IC50 of 0.5 μM. It inhibits CDC5L phosphorylation and exhibits profound effects on cell proliferation. This product is for research use only.
- Potent, selective, reversible, and ATP-competitive inhibitor of CDK2
- IC50 of 0.5 μM for CDK2
- Inhibits CDC5L phosphorylation
- Exhibits profound effects on cell proliferation at 5-20 μM
- For research use only
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Medchemexpress LLC Menin-MLL inhibitor MI-2 | 1271738-62-5 | C18H25N5S2 | 1 ML
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Menin-MLL inhibitor MI-2 is a competitive and selective Menin-MLL interaction inhibitor. It effectively downregulates target genes like HOXA9 and MEIS1, leading to inhibition of leukemia cell proliferation and induction of apoptosis and differentiation. This compound shows promise in the research of MLL-rearranged acute leukemias, including AML and ALL, with an IC50 of 446 nM and a Ki value of 158 nM.
- Competitive and selective Menin-MLL interaction inhibitor
- Downregulates expression of target genes (HOXA9, MEIS1)
- Inhibits proliferation of leukemia cells
- Induces apoptosis and differentiation
- Promising for research of MLL-rearranged acute leukemias
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Medchemexpress LLC HY-108593 5mg Medchemexpress, BMS-191011 CAS:202821-81-6 Purity:>98%
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Medchemexpress, HY-108593 5mg BMS-191011 CAS:202821-81-6 BMS-191011 (BMS-A) is an opener of the large-conductance, Ca 2+ +-activated potassium (maxi-K) channel , effective in stroke models [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000380902 IONIS-MAPTRX SODIUM 1MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000382863 CAPMATINIB DIHYDROC 25MG
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eMolecules ChemScene / 2-Fluoro-4-iodophenol / 10g / 536847430 / CS-W005152 / 0.000 / 2713-28-2 / MFCD11109769 / 238.000 / C6H4FIO
ChemScene / 2-Fluoro-4-iodophenol / 10g / 536847430 / CS-W005152 / 0.000 / 2713-28-2 / MFCD11109769 / 238.000 / C6H4FIO
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eMolecules MPATRT 100G
5000158804 MPATRT 100G
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![Medchemexpress LLC 4-Piperidineacetic acid, 1-[[1-phenyl-3-(2-thienyl)-1H-pyrazol-5-yl]carbonyl]-, methyl ester | 1282128-68-0 | 98.0% | 409.50 | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000384681-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 4-Piperidineacetic acid, 1-[[1-phenyl-3-(2-thienyl)-1H-pyrazol-5-yl]carbonyl]-, methyl ester | 1282128-68-0 | 98.0% | 409.50 | 1 ML
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KB-208 is a phagocytosis inhibitor that improves immune thrombocytopenia (ITP) in mouse models. It is suitable for immunology research.
- Improves immune thrombocytopenia (ITP) in mouse models
- Does not affect other blood parameters
- Does not elevate serum toxicity biomarkers
- For research use only
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Medchemexpress LLC L-Tyrosinamide | 4985-46-0 | 98.95% | 180.20 | 25 G
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L-Tyrosinamide is a derivative of Tyrosine, which is an amino acid amide.
- Purity of 98.95%
- Molecular weight of 180.20
- Appears as a solid
- Store at 4°C under nitrogen
- Solvent storage at -80°C for 6 months or -20°C for 1 month under nitrogen
- Soluble in DMSO at 100 mg/mL
- For research use only
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