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Filtered Search Results
Apexbio Technology LLC WAY-100635 maleate salt 1092679-51-0 100mg
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WAY-100635 maleate salt (CAS 1092679-51-0) is a selective antagonist of the serotonin 5-HT1A receptor subtype It demonstrates high potency with a reported pIC50 value of 8 87 and displays over 100-fold selectivity relative to other serotonin receptor isoforms and common neurotransmitter receptor classes Due to its specific interaction with 5-HT1A receptors WAY-100635 maleate is frequently applied in neuroscience research to elucidate serotonin-mediated pathways and associated physiological or behavioral responses
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Medchemexpress LLC Sumanirole maleate | 179386-44-8 | 99.8% | C15H17N3O5 | 50 MG
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Sumanirole maleate is a highly selective full agonist of the D2 receptor, exhibiting an ED50 of approximately 46 nM. This compound is significant in the study of Parkinson's disease and restless leg syndrome. It serves as a valuable research tool for investigating neurobiological mechanisms that are specifically linked to dopamine D2 receptor activity.
- Highly selective full agonist of the D2 receptor.
- Involved in research concerning Parkinson's disease.
- Used in the study of restless leg syndrome.
- Aids in identifying neurobiological mechanisms dependent on D2 receptor linkage.
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eMolecules 34675-24-6 | (-)-DIMENTHYL FUMARATE | AstaTech | MFCD00075423 | 392.580 | C24H40O4 | 95.000 | CC(C)[C@@H]1CC[C@@H](C)C[C@H]1OC(=O)\C=C\C(=O)O[C@H]1C[C@@H](C)CC[C@@H]1C(C)C | 1g | 410712751
(-)-DIMENTHYL FUMARATE | AstaTech | 34675-24-6 | MFCD00075423 | 392.580 | C24H40O4 | 95.000 | CC(C)[C@@H]1CC[C@@H](C)C[C@H]1OC(=O)\C=C\C(=O)O[C@H]1C[C@@H](C)CC[C@@H]1C(C)C | 1g | 410712751
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Medchemexpress LLC Setiptiline (maleate) | 85650-57-3 | 99.9% | 377.43 | 100 MG
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Setiptiline maleate is a serotonin receptor antagonist. It is classified as a tetracyclic antidepressant (TeCA) and acts as a noradrenergic and specific serotonergic antidepressant (NaSSA). It functions as a norepinephrine reuptake inhibitor, an α2-adrenergic receptor antagonist, and a serotonin receptor antagonist, potentially targeting the 5-HT2A, 5-HT2C, and/or 5-HT3 subtypes. Additionally, it acts as an H1 receptor inverse agonist/antihistamine. It is intended for research use only.
- Serotonin receptor antagonist
- Tetracyclic antidepressant (TeCA)
- Noradrenergic and specific serotonergic antidepressant (NaSSA)
- Norepinephrine reuptake inhibitor
- Alpha2-adrenergic receptor antagonist
- Antagonizes serotonin receptor subtypes: 5-HT2A, 5-HT2C, and/or 5-HT3
- H1 receptor inverse agonist/antihistamine
- Purity: 99.94%
- Appearance: Solid
- Color: White to gray
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Medchemexpress LLC Pimethixene maleate | 13187-06-9 | 99.7% | 5 MG
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Pimethixene maleate is an antihistamine and antiserotonergic compound that acts as an antimigraine agent. It is a highly potent antagonist of 5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, histamine H1, dopamine D2 and D4.4, as well as muscarinic M1 and M2 receptors. The pKis for these receptors are 7.63, 10.22, 10.44, 8.42, 10.14, 8.19, 7.54, 8.61, and 9.38, respectively.
- Antihistamine and antiserotonergic compound.
- Acts as an antimigraine agent.
- Highly potent antagonist of multiple receptors including 5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, histamine H1, dopamine D2 and D4.4, and muscarinic M1 and M2.
- For research use only.
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Medchemexpress LLC Enalapril (maleate) | 76095-16-4 | 99.95% | 250 MG
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Enalapril maleate, also known as MK-421 maleate, is the active metabolite of enalapril and functions as an angiotensin-converting enzyme (ACE) inhibitor. Enalapril is a prodrug that is rapidly metabolized in the liver to enalaprilat following oral administration. It is a potent, competitive inhibitor of ACE, which is responsible for converting angiotensin I to angiotensin II, a key regulator of blood pressure. Enalapril may be used to treat essential or renovascular hypertension and symptomatic congestive heart failure. This product is for research use only.
- Harmful if swallowed.
- Causes skin and serious eye irritation.
- May cause respiratory irritation.
- Avoid breathing dust, fume, gas, mist, vapors, or spray.
- Keep container tightly sealed in a cool, well-ventilated area, away from moisture and direct sunlight.
- Wear protective gloves, clothing, eye protection, and face protection.
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Apexbio Technology LLC WAY-100635 maleate salt 1092679-51-0 50mg
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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WAY-100635 maleate salt (CAS 1092679-51-0) is a selective antagonist of the serotonin 5-HT1A receptor subtype It demonstrates high potency with a reported pIC50 value of 8 87 and displays over 100-fold selectivity relative to other serotonin receptor isoforms and common neurotransmitter receptor classes Due to its specific interaction with 5-HT1A receptors WAY-100635 maleate is frequently applied in neuroscience research to elucidate serotonin-mediated pathways and associated physiological or behavioral responses
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Medchemexpress LLC Omigapil maleate | 200189-97-5 | 99.84% | 391.42 | 1 ML
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Omigapil maleate (CGP3466B) is an orally active GAPDH nitrosylation inhibitor. It has been shown to abrogate Aβ1-42-induced tau acetylation, memory impairment, and locomotor dysfunction in mice. This compound holds potential for research in Alzheimer's disease and congenital muscular dystrophy (CMD), and it also acts as an apoptosis inhibitor. Additionally, Omigapil maleate is a click chemistry reagent, possessing an Alkyne group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Orally active GAPDH nitrosylation inhibitor
- Aβ1-42-induced tau acetylation, memory impairment, and locomotor dysfunction abrogator
- Potential for Alzheimer's disease research
- Apoptosis inhibitor
- Can be used for congenital muscular dystrophy (CMD) research
- Click chemistry reagent with an Alkyne group for CuAAc reactions
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Medchemexpress LLC Cediranib maleate | 857036-77-2 | 99.95% | 25 MG
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Cediranib maleate is a highly potent, orally available VEGFR inhibitor. It demonstrates inhibitory activity against Flt1, KDR, Flt4, PDGFRα, PDGFRβ, and c-Kit. This compound is intended for research use only.
- Inhibits VEGF-stimulated proliferation and KDR phosphorylation in human umbilical vein endothelial cells.
- Reduces vessel area, length, and branching in a fibroblast/endothelial cell coculture model.
- Ablates experimental (VEGF-induced) angiogenesis in vivo.
- Inhibits endochondral ossification and corpora luteal development.
- Dose-dependently inhibits the growth of human tumor xenografts (colon, lung, prostate, breast, and ovary) in athymic mice.
- Shows a reduction in microvessel density within tumors, indicating vascular regression.
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Apexbio Technology LLC Timolol Maleate 26921-17-5 10mM (in 1mL DMSO)
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Timolol Maleate (CAS 26921-17-5) is the maleate salt form of the (S)-enantiomer of Timolol a potent non-selective -adrenergic receptor antagonist It exhibits high binding affinity toward both 1 and 2 adrenergic receptor subtypes with reported Ki values of approximately 1 97 nM ( 1) and 2 0 nM ( 2) Timolol maleate functions by competitively blocking adrenergic signaling pathways thus modulating sympathetic nervous system activities It is widely utilized in biomedical research to investigate -adrenergic signal transduction mechanisms and associated physiological processes including cardiac function and ophthalmic conditions
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Medchemexpress LLC Tris (maleate) | 72200-76-1 | MFCD00082442 | 98.0% | 237.21 g/mol | C8H15NO7 | 10 G
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Tris (maleate) is the maleate salt of tris(hydroxymethyl)aminomethane used as a buffering agent in biochemical and cell biology applications. It stabilizes pH in growth media, tissue preparations, and washing or diluent solutions, and is supplied as a highly soluble reagent to support reproducible experimental workflows.
- Buffered pH support for media and tissue preparations.
- Water-soluble; also soluble in DMSO with sonication if needed.
- High purity: 98.0%.
- Suitable for use as a diluent or washing buffer.
- Available in laboratory-scale package sizes such as 10 G.
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eMolecules 19932-26-4 | AstaTech | 3-(2233-TETRAFLUOROPROPOXY)-12-EPOXYPROPANE | 5g | 718075182 | D95663 | 95 | MFCD00054682 | 188.122 | C6H8F4O2
ChemScene | 1-Ethynylpyrene | 1g | 582647262 | CS-0134957 | 34993-56-1 | MFCD02093933 | 226.278 | C18H10
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Medchemexpress LLC HY-100350 1mg Medchemexpress, CA-074 methyl ester CAS:147859-80-1 Purity:>98%
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Medchemexpress, HY-100350 1mg CA-074 methyl ester CAS:147859-80-1 CA-074 methyl ester is a specific inhibitor of Cathepsin B , which has potent bioactivities such as neuroprotective, anti-cancer, and anti-inflamatory effects. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000664281 CYCLOMARIN MONOMER-1 10MM/1ML
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Medchemexpress LLC HQ-415 | 430462-93-4 | 98.1% | 415.48 | C25H25N3O3 | 10 MG
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HQ-415 is a biologically active metal chelator related to clioquinol, reported to have an EC50 of 15 μM. It is supplied as a research reagent for laboratory studies of metal chelation and related biochemical assays.
- Biologically active metal chelator related to clioquinol.
- Reported EC50 15 μM.
- Molecular formula C25H25N3O3; molecular weight 415.48.
- Purity 98.1%.
- Available in small research pack sizes: 1 mg, 5 mg, 10 mg.
- Storage: powder at -20°C for long-term; in solvent store at -80°C when possible.
- For research use only; not for human or animal therapeutic use.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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