Tricarboxylic acids and derivatives
Medchemexpress LLC 5,8,11,14,17,20-hexaoxa-2-azadocosanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester | 437655-96-4 | 99.4% | 561.62 | C29H39NO10 | 250 MG
Fmoc-NH-PEG6-CH2COOH is an Fmoc-protected polyethylene glycol (PEG6) linker with a terminal carboxylic acid, supplied for research use as a cleavable linker for antibody-drug conjugates and as a PEG-based PROTAC linker in targeted protein degradation research.
- Fmoc-protected amine with terminal carboxylic acid functionality.
- Suitable for ADC and PROTAC linker synthesis.
- Reported purity 99.4% and molecular weight 561.62.
- Molecular formula C29H39NO10.
- Available in small-scale pack sizes including 250 MG.
Medchemexpress LLC Amino-PEG3-CH2COOH | 134978-99-7 | 99.9% | C8H17NO5 | 100 MG
Amino-PEG3-CH2COOH is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker, with one targeting an E3 ubiquitin ligase and the other targeting the protein of interest. This mechanism exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Contains two different ligands connected by a linker
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC Diphosphoric acid, mono[(2E)-4-hydroxy-3-methyl-2-butenyl] ester, triammonium salt | 443892-56-6 | 90.0% | C5H21N3O8P2 | 500 UG
HDMAPP triammonium is a potent phosphoantigen in the ammonium and pyrophosphate form of (E)-HDMAPP. It is an activator of γδ T cells and can induce T cell stimulation in vitro with an EC₅₀ of 0.39 nM for TNF-α release.
- Potent phosphoantigen
- Activates γδ T cells
- Induces T cell stimulation in vitro
- Increases TNF-α release in human Vγ9Vδ2 T cells
- Significantly increases γδ cells in cynomolgus monkey model
- White to off-white solid appearance
Strem, An Ascensus Company CAS# 51805-45-9. 5g. Tris(2-carboxyethyl)phosphine, hydrochloride, 99% TCEP. MFCD00145469
CAS# 51805-45-9. 5g. Tris(2-carboxyethyl)phosphine, hydrochloride, 99% TCEP. MFCD00145469. Molecular Weight: 286.65. Molecular Formula: (HOOCCH2CH2)3PH+Clae. Color/form: white xtl. Strem# 15-7400. http://www.strem.com/catalog/v/15-7400/
![eMolecules 68-04-2 | Sodium citrate, anhydrous | Oakwood Chemical | MFCD00012462 | 258.068 | C6H5Na3O7 | 99.000 | [Na+].[Na+].[Na+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O | 100g | 850217555](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000188853.jpg-250.jpg)
eMolecules 68-04-2 | Sodium citrate, anhydrous | Oakwood Chemical | MFCD00012462 | 258.068 | C6H5Na3O7 | 99.000 | [Na+].[Na+].[Na+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O | 100g | 850217555
Sodium citrate, anhydrous | Oakwood Chemical | 68-04-2 | MFCD00012462 | 258.068 | C6H5Na3O7 | 99.000 | [Na+].[Na+].[Na+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O | 100g | 850217555
N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(F)c(F)cc1F | 25g | 624127118](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502171601.JPG-250.jpg)
eMolecules 654671-77-9 | SITAGPLIPTIN PHOSPHATE MONOHYDRATE | AstaTech | MFCD10001393 | 523.329 | C16H20F6N5O6P | 99.000 | O.OP(O)(O)=O.N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(F)c(F)cc1F | 25g | 624127118
SITAGPLIPTIN PHOSPHATE MONOHYDRATE | AstaTech | 654671-77-9 | MFCD10001393 | 523.329 | C16H20F6N5O6P | 99.000 | O.OP(O)(O)=O.N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(F)c(F)cc1F | 25g | 624127118
TARGETMOL CHEMICALS INC Zoledronic acid monohydrate
Also available in 10 mg, 25 mg, 50 mg, 200 mg, 500 mg and bulk. Please contact Fisher for quotes. Zoledronic acid monohydrate (CGP 42446) is a synthetic imidazole bisphosphonate analog with anti-bone-resorption activity. Purity ≥95%
Medchemexpress LLC Pacritinib (citrate) | 1228923-42-9 | 99.7% | 664.70 | 1 ML
Pacritinib (SB1518) citrate is a potent inhibitor of both wild-type JAK2 (IC50=23 nM) and JAK2V617F mutant (IC50=19 nM). It also inhibits FLT3 (IC50=22 nM) and its mutant FLT3D835Y (IC50=6 nM). This compound can be used for the research of acute myeloid leukemia (AML) and myelofibrosis (MF).
- Potent inhibitor of wild-type JAK2 (IC50=23 nM)
- Potent inhibitor of JAK2V617F mutant (IC50=19 nM)
- Inhibits FLT3 (IC50=22 nM)
- Inhibits FLT3D835Y mutant (IC50=6 nM)
- Used for research in acute myeloid leukemia (AML) and myelofibrosis (MF)
Medchemexpress LLC Ferric citrate | 3522-50-7 | 244.94 | 100 MG
Ferric citrate (Iron(III) citrate) is an orally active iron supplement and an efficacious phosphate binder. It is used for research related to iron deficiency anemia and chronic kidney disease (CKD).
- Orally active iron supplement.
- Efficacious phosphate binder.
- Can be used for iron deficiency anemia and chronic kidney disease (CKD) research.
- Reduces fibroblast growth factor 23 levels and improves renal and cardiac function in a mouse model of chronic kidney disease.
- Increases iron stores and reduces intravenous iron and erythropoietin-stimulating agent use while maintaining hemoglobin.
- Can increase transferrin saturation, serum ferritin, and hemoglobin.
Medchemexpress LLC 2-methylcitric acid trisodium | 117041-96-0 | MFCD16875437 | 96.0% | 272.10 g·mol⁻1 | C7H7Na3O7 | 5 MG
2-Methylcitric acid trisodium is the trisodium salt of 2-methylcitric acid provided as a white to off-white solid for laboratory research. It is an endogenous metabolite used as a marker in methylmalonic and propionic acidemias and is employed in biochemical and mitochondrial studies, where it has been reported to inhibit ADP-stimulated mitochondrial respiration supported by glutamate.
- Trisodium salt, white to off-white solid.
- CAS number 117041-96-0.
- Purity 96.0%.
- Molecular weight 272.10 g·mol⁻1; formula C7H7Na3O7.
- Highly soluble in water (100 mg/mL; may require ultrasonication).
- Storage: sealed at 4°C; in solvent -80°C (6 months), -20°C (1 month).
- For research use only; not for human or veterinary use.
Teknova 20mM Sodium Citrate, 8% Sucrose, pH 6.0. 500mL, Endotoxin Tested, Sterile. 8 pack.
20mM Sodium Citrate, 8% Sucrose, pH 6.0. 500mL, Endotoxin Tested, Sterile. 8 pack.
Medchemexpress LLC Boc-NH-PEG1-CH2COOH | 142929-49-5 | 98.0% | C9H17NO5 | 1 G
Boc-NH-PEG1-CH2COOH is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Molecular weight: 219.23
- Appearance: Solid-liquid mixture
- Color: Colorless to light yellow
- SMILES: O=C(O)COCCNC(OC(C)(C)C)=O
- Storage (pure form): -20°C for 3 years, 4°C for 2 years
- Storage (in solvent): -80°C for 6 months, -20°C for 1 month
- Solubility (in vitro): DMSO at 100 mg/mL (456.14 mM)
- Solubility (in vivo): Protocols available for DMSO, PEG300, Tween-80, Saline, SBE-β-CD, and Corn Oil
Medchemexpress LLC Bromo-PEG1-CH2COOH | 1135131-50-8 | >=97.0% | 100 MG
Bromo-PEG1-CH2COOH is a PROTAC linker, designed for use in the synthesis of PROTACs. These molecules exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins, by connecting an E3 ubiquitin ligase ligand to a target protein ligand.
- Used as a PROTAC linker
- Designed for PROTAC synthesis
- Contains two ligands connected by a linker
- One ligand targets an E3 ubiquitin ligase
- Other ligand targets a protein
- Exploits the ubiquitin-proteasome system
- Enables selective degradation of target proteins
- For research use only
eMolecules 23142-01-0 | Pentoxyverine citrate | MFCD00055697 | 1g
Ambeed | rel-(3R4S5S6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2345-tetraol | 1g | 649269182 | A1497324 | 54-17-1 | MFCD00063684 | 180.156 | C6H12O6
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Medchemexpress LLC DiMal-O-CH2COOH | 1620837-47-9 | 96.8% | 308.24 | C13H12N2O7 | 10 MG
This cleavable linker is designed for use in antibody-drug conjugate (ADC) construction and conjugation workflows, offering malemide-based chemistry for attaching payloads to antibodies or targeting moieties. It is provided at research-grade purity and supplied in small quantities suitable for method development and exploratory studies.
- Cleavable linker for ADC construction and conjugation workflows.
- Provides maleimide-based chemistry for reliable payload attachment.
- High purity (96.8%) suitable for research applications.
- Available in small research quantities; larger amounts available on request.
- Store at 4°C, protect from light; in solvent: -80°C (6 months) or -20°C (1 month).