Thiazoles
Medchemexpress LLC Blue tetrazolium (tetrazolium blue) | 1871-22-3 | 99.8% | 500 MG
Blue Tetrazolium (Tetrazolium blue) is a blue dye used for microbial research. It can be reduced into blue tetrazolium formazan (BTF). Blue Tetrazolium can be used to determine the activity of succinate dehydrogenase (SDH) in yeast strains, where it is reduced as a substrate. DMSO can be used to extract BTF from cells, and the absorption spectrum of BTF can be tested. BTF exhibits a wide wavelength range of 480-600 nm with a maximal absorbance at 540 nm. Blue Tetrazolium combines with succinate dehydrogenase (SDH).
- Molecular weight: 727.64
- Formula: C40H32Cl2N8O2
- Appearance: Solid
- Color: Light yellow to yellow
- Shipping: Room temperature in continental US; may vary elsewhere
- Storage: RT, sealed storage, away from moisture and light. In solvent: -80°C for 1 year, -20°C for 6 months
Medchemexpress LLC Yx-02-030 | 3049076-98-1 | 99.9% | 1267.41 | C66H85Cl2N9O10S | 10 MG
A PROTAC small-molecule degrader that targets MDM2 for research use in biochemical and cell-based assays. It binds MDM2 and recruits the VHL E3 ubiquitin ligase to induce proteasomal degradation of MDM2, disrupting MDM2-p53 interactions.
- High purity (≈99.9%).
- Available as a 10 mg research pack suitable for assay development.
- Potent inhibition of MDM2-p53 binding and VHL engagement in biochemical assays.
- Molecular weight 1267.41; formula C66H85Cl2N9O10S.
- Provided with an SDS for handling and storage guidance.
Medchemexpress LLC Thiazole orange dimer YOYO 1 | 143413-85-8 | 97.0% | 635 UG
Thiazole orange dimer YOYO 1 is a green fluorescent dye utilized for DNA staining. It is a monomethine cyanine dye, presenting as a tetracationic homodimer of oxazole yellow (YO), and is typically supplied as a tetraiodide salt. While exhibiting low fluorescence in aqueous buffer, its intensity significantly increases upon binding to double-stranded DNA through diintercalation.
- Green fluorescent dye
- Used for DNA staining
- Monomethine cyanine dye family
- Tetracationic homodimer of oxazole yellow
- Fluorescence increases 3200 times upon binding to double-stranded DNA
Medchemexpress LLC Solvent Yellow 93 (C.I. 48160) | 4702-90-3 | 99.1% | 100 MG
Solvent Yellow 93 (C.I. 48160) is an azomethine dye characterized by its yellow to orange appearance and high purity. It is primarily used as a versatile colorant in various industrial applications.
- Used as a colorant for toners
- Suitable for coloring polyester fiber pulp
- Applied in the production of polyester masterbatch
Medchemexpress LLC Blue Tetrazolium | 1871-22-3 | 99.8% | 1 G
Blue Tetrazolium is a blue dye used in microbial research. It can be reduced into blue tetrazolium formazan (BTF) and is suitable for determining the activity of succinate dehydrogenase (SDH) in yeast strains. The BTF can be extracted from cells using DMSO, and its absorption spectrum can be tested, showing a wide wavelength range of 480-600 nm with maximal absorbance at 540 nm.
- Blue dye for microbial research.
- Can be reduced into blue tetrazolium formazan (BTF).
- Used to determine the activity of succinate dehydrogenase (SDH) in yeast strains.
- BTF exhibits a wide wavelength range of 480-600 nm with maximal absorbance at 540 nm.
- Combines with succinate dehydrogenase (SDH).
Medchemexpress LLC Thiazole Orange | 107091-89-4 | 99.6% | 1 G
Thiazole Orange | 107091-89-4 | 99.6% | 1 G
Medchemexpress LLC BAY-298 | 2471978-97-7 | 100.0% | 25 MG
BAY-298 is an orally active and selective luteinizing hormone receptor (LH-R) antagonist that can reduce sex hormone levels, making it suitable for research applications related to metabolic or endocrine diseases.
- Orally active and selective luteinizing hormone receptor (LH-R) antagonist.
- Reduces sex hormone levels.
- Inhibits human ERG in HEK293 cells (IC50: 3 μM).
- Exhibits antagonist activity at cynomolgus monkey luteinizing hormone receptor in HEK293 cells (IC50: 78 nM).
- Lowers serum estradiol levels in intact female rats.
Medchemexpress LLC c-Met-IN-15 | 330572-32-2 | 98.5% | 299.26 | 5 MG
c-Met-IN-15 (compound S3) is a c-Met kinase inhibitor. It inhibits c-Met kinase activity.
- Inhibits c-Met kinase activity of 21.1% at the concentration of 10 μM.
- For research use only.
Medchemexpress LLC TH-6 | 3031349-25-1 | 95.0% | 429.44 | 5 MG
TH-6 is a potent HDAC inhibitor that targets HDAC1, HDAC2, HDAC3, HDAC6, and HDAC8. This compound has demonstrated anti-tumor activity by inhibiting cell migration and invasion, and inducing apoptosis and cell cycle arrest at the G2/M phase.
- Potent HDAC inhibitor
- Inhibits cell migration and invasion
- Induces apoptosis
- Induces cell cycle arrest at G2/M phase
- Demonstrates anti-tumor activity
- For research use only
Medchemexpress LLC 2-(4-butoxy-3-cyanophenyl)-4-methyl-1,3-thiazole-5-carboxylic acid | 1657014-33-9 | MFCD31652176 | ≥98.0% | C16H16N2O3S | 10MG
Febuxostat n-butyl isomer is an analytical reference standard and a known impurity of febuxostat. It is intended for research and quality-control applications, including impurity profiling, method development, and analytical validation for xanthine oxidase inhibitor products. The compound has molecular formula C16H16N2O3S and molecular weight 316.37 g·mol⁻1, and is offered at high purity for laboratory use.
- High purity (≥98.0%) suitable for analytical and reference use.
- Supports impurity profiling and method development for febuxostat-related products.
- Available in small reference quantities and larger sizes by request.
- Chemical identity confirmed by CAS number and structural data for reliable traceability.
- Supplied for research and quality-control applications, not for human use.
Medchemexpress LLC Boc-bipiperidine-ethynylbenzoic acid | 2308497-81-4 | 99.19% | 412.52 | 25 MG
Boc-bipiperidine-ethynylbenzoic acid is an alkyl/ether-based PROTAC linker that can be used in the synthesis of ARD-61. It also acts as a click chemistry reagent, containing an alkyne group capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules possessing azide groups.
- Alkyl/ether-based PROTAC linker
- Used in the synthesis of ARD-61
- Functions as a click chemistry reagent
- Contains an alkyne group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Appears as a white to off-white solid
- High purity of 99.19%
- Molecular weight of 412.52
Medchemexpress LLC Methyltetrazine-amine | 1345955-28-3 | MFCD28334555 | 99.4% | C10H11N5 | 10MG
Methyltetrazine-amine is a tetrazine-based reagent used as a bioorthogonal handle for site-specific dual functionalization of biomolecules. It is supplied as a pink to purplish-red solid (C10H11N5, MW 201.23) for research use, with high reported purity and storage guidance to protect from light.
- Acts as a tetrazine bioorthogonal handle for rapid conjugation.
- Enables site-specific dual functionalization of biomolecules.
- Provided as a stable pink to purplish-red solid for easy handling.
- High purity suitable for analytical and preparative applications.
- Stable when stored protected from light; solvent storage at low temperatures recommended.
- Soluble in common polar organic solvents such as DMSO and DMF.
Medchemexpress LLC γ-Linolenic acid ethyl ester | 31450-14-3 | 99.14% | 306.48 | 100 MG
γ-Linolenic acid ethyl ester (Ethyl γ-linolenate) is a leukotriene B4 receptor 4 (LTB4) antagonist.
- Leukotriene B4 receptor 4 (LTB4) antagonist.