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Hydroxybenzoic Acid Derivatives

Organic compounds that are directly derived from hydroxybenzoic acid; hydroxybenzoic acid consists of benzoic acid with a hydroxyl group substitution.

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1

eMolecules​ 4-Bromo-2-fluorobenzamide | 292621-45-5 | MFCD03094432 | 1g

Apollo Scientific | 4-Bromo-2-fluorobenzamide | 1g | 562442308 | PC7599 | | 292621-45-5 | MFCD03094432 | 218.025 | C7H5BrFNO

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2

Medchemexpress LLC (±)-Coriolic acid | 18104-45-5 | 99.0% | 296.44 | 100 UG
SDP

(±)-Coriolic acid is one of the two racemic monohydroxy fatty acids resulting from the non-enzymatic oxidation of linoleic acid. It is the principal hydroxylated fatty acid in human psoriatic skin scales, with a mean concentration of 17 ng/mg.

  • Racemic monohydroxy fatty acid
  • Results from non-enzymatic oxidation of linoleic acid
  • Principal hydroxylated fatty acid in human psoriatic skin scales
  • Functions as an endogenous metabolite
  • Involved in metabolic enzyme/protease pathways
  • Stable under recommended storage conditions
  • Recommended for research use only
  • Store as a solution at -20°C for up to 2 years

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3

Medchemexpress LLC 2-Chloro-5-nitropyridine | 4548-45-2 | 99.5% | 158.54 | 25 G
SDP

2-Chloro-5-nitropyridine is a biochemical reagent that can be used as a biological material or organic compound for life science-related research. It is also used as a pharmaceutical intermediate. This product is for research use only and not sold to patients.

  • Can be used as a biochemical reagent
  • Can be used as a biological material
  • Organic compound for life science-related research
  • Used as a pharmaceutical intermediate

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4

Medchemexpress LLC 3-sulfopropanoic acid | 44826-45-1 | MFCD19347139 | 95.0% | 154.14 g/mol | C3H6O5S | 5 MG
SDP

3-Sulfopropanoic acid is an endogenous sulfonic acid used as a research reagent in biochemical and metabolic studies. Supplied as a solid, it is suitable for analytical and preparative laboratory applications.

  • Purity 95.0%.
  • Molecular formula C3H6O5S.
  • Molecular weight 154.14 g/mol.
  • Appearance: colorless to off-white solid.
  • Available in small milligram quantities for research use.
  • Contains a propanoic acid backbone with a sulfonic acid functional group, enabling solubility in polar solvents.

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5

Medchemexpress LLC 2H-Pyran-2,4(3H)-dione, 3-acetyl-6-methyl- | 520-45-6 | 99.9% | 5 G
SDP

Dehydroacetic acid (Biocide 470F) is a pyrone derivative with antibacterial, antifungal, and phytotoxic activities. It can be used in cosmetics, food, and beverages for preservation. Additionally, it can be utilized in the synthesis of various heterocycles and cycloaddition products.

  • Antibacterial activity
  • Antifungal activity
  • Phytotoxic activity

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6

eMolecules​ Pharmablock 5-bromo-4-fluoro-2-nitro-benzaldehyde 250mg 736632216 PBT5580 0 000 213382-45-7 MFCD00456499 248 007 C7H3BrFNO3

Pharmablock 5-bromo-4-fluoro-2-nitro-benzaldehyde 250mg 736632216 PBT5580 0 000 213382-45-7 MFCD00456499 248 007 C7H3BrFNO3

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7

Matrix Scientific 2-BROMO-6-METHOXYBENZOIC AC-5G

2-Bromo-6-methoxybenzoic acid, 97%; 5g,C8H7BrO3, MFCD00800732, mw 231.05, [31786-45-5]

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8

Selleck Chemical LLC Amitriptyline HCl S3183-1g

Amitriptyline HCl is an inhibitor of both serotonin transporter (SERT) and norepinephrine transporter (NET) with Ki of 3 45 nM and 13 3 nM respectively Amitriptyline HCl also inhibits histamine receptor H1 histamine receptor H4 5-HT2 and sigma 1 receptor with Ki of 0 5 nM 7 31 nM 235 nM and 287 nM respectively Amitriptyline is a tricyclic antidepressant (TCA)

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9

TARGETMOL CHEMICALS INC ELAFIBRANOR 25MG
SDP

Also available in 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Elafibranor (GFT505) is an agonist of the peroxisome proliferator-activated receptor-(alpha) (PPAR-(alpha)) and peroxisome proliferator-activated receptor-(delta) (PPAR-(delta)) with EC50 values of 45 and 175 nM respectively. purity: 99%

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10

Medchemexpress LLC Adenosine, 5'-deoxy-5'-fluoro | 731-98-6 | Not available | 96.2% | 269.23 g/mol | C10H12FN5O3 | 50 MG
SDP

5′-Fluoro-5′-deoxyadenosine is a fluorinated adenosine nucleoside supplied as a research reagent for studies of nucleoside chemistry, enzymatic fluorination, and related in vitro and in vivo assays. It is intended for research use only.

  • High purity (96.2%) suitable for biochemical assays.
  • Molecular formula C10H12FN5O3; molecular weight 269.23 g/mol.
  • CAS number 731-98-6 for unambiguous identification.
  • Soluble in DMSO at 20 mg/mL (use freshly opened DMSO; adjust pH as directed).
  • In vivo formulations supported: ≥2 mg/mL in 10% DMSO/40% PEG300/5% Tween-80/45% saline, or in 10% DMSO with 20% SBE-β-CD in saline.
  • Storage: store at 4°C under nitrogen, protect from moisture; in solution store at -80°C up to 6 months or -20°C up to 1 month.
  • For research use only; not for human or clinical use.

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11

Medchemexpress LLC SN38-COOH | 2170118-23-5 | 96.1% | 492.48 g/mol | C26H24N2O8 | 10 MG
SDP

SN38-COOH is a carboxylated derivative of SN-38, the active metabolite of the topoisomerase I inhibitor irinotecan, supplied as a research reagent for the synthesis of antibody-drug conjugates (ADCs) and conjugation chemistry. It is provided as a powder with specified storage and solubility profiles for in vitro and in vivo use.

  • Carboxylated SN-38 derivative for ADC synthesis.
  • Molecular formula C26H24N2O8; molecular weight 492.48 g/mol.
  • CAS number 2170118-23-5.
  • Purity 96.1%.
  • Storage: powder -20°C (stable up to 3 years); in solvent -80°C for 6 months, -20°C for 1 month.
  • In vitro solubility: DMSO 100 mg/mL with sonication and heating to 60°C.
  • In vivo formulation example provided: 10% DMSO, 40% PEG300, 5% Tween-80, 45% saline (2.5 mg/mL).

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12

Medchemexpress LLC (E)-2-cyano-3-[1-[3-(dimethylamino)propyl]indol-3-yl]-N-octylprop-2-enamide | 1128165-88-7 | MFCD19690957 | 99.3% | 408.58 g·mol⁻¹ | C25H36N4O | 1 MG
SDP

Dynole 34-2 is a small-molecule inhibitor of dynamin GTPases used in cell biology to block receptor-mediated endocytosis and induce apoptosis. It is supplied as a light-yellow solid at high purity for in vitro and in vivo research.

  • Potent dynamin GTPase inhibitor (IC50 ≈ 6.9 μM for dynamin-1, 14.2 μM for dynamin-2).
  • High purity (99.3%).
  • Molecular weight 408.58 g·mol⁻¹.
  • Chemical formula C25H36N4O.
  • Soluble in DMSO (100 mg/mL); in vivo formulations: 10% DMSO/40% PEG300/5% Tween-80/45% saline or 10% DMSO/90% corn oil.
  • Storage: solid at 4°C protected from light; solutions at -80°C up to 6 months or -20°C up to 1 month.

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13

Medchemexpress LLC Chelidonic acid | 99-32-1 | MFCD00006577 | >98.0% | 184.10 g/mol | C7H4O6 | 1 ML
SDP

Chelidonic acid is a small-molecule research compound (CAS 99-32-1) reported to modulate NF-κB and caspase-related pathways. The compound is described as a powder with defined solubility and storage recommendations for in vitro and in vivo use.

  • chemical formula: C7H4O6.
  • molecular weight: 184.10 g/mol.
  • purity: >98% (as listed by distributors).
  • solubility: soluble in DMSO (10 mg/mL, with warming/ultrasonic); aqueous solubility approximately 2.5 mg/mL with ultrasonic assistance.
  • recommended in vivo formulation: sequential addition of solvents (10% DMSO → 40% PEG300 → 5% Tween-80 → 45% saline) to obtain a clear solution.
  • storage: powder -20°C (up to 3 years) or 4°C (up to 2 years); in solvent -80°C (6 months) or -20°C (1 month).

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14

Medchemexpress LLC Mefenamic acid | 61-68-7 | 10 G
SDP

Mefenamic acid is a BBB-permeable and non-steroidal anti-inflammatory agent. It acts as a competitive inhibitor of hCOX-1 and hCOX-2, with IC50s of 40 nM and 3 μM for hCOX-1 and hCOX-2, respectively. Mefenamic acid (0-100 μM) has cytotoxic effects on KB, Saos-2, and 1321N cells, however, U-87MG cells are resistant to Mefenamic acid.

  • Molecular formula: C15H15NO2
  • Molecular weight: 241.29
  • Target: COX
  • Pathway: Immunology/Inflammation
  • Solubility in vitro: DMSO: ≥ 100 mg/mL (414.44 mM), H2O: < 0.1 mg/mL (insoluble)
  • Solubility in vivo: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline: 2.5 mg/mL (10.36 mM); 10% DMSO >> 90% corn oil: ≥ 2.5 mg/mL (10.36 mM)
  • Storage (powder): -20°C for 3 years, 4°C for 2 years
  • Storage (in solvent): -80°C for 2 years, -20°C for 1 year

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