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Filtered Search Results
Medchemexpress LLC Sotorasib | 2296729-00-3 | 100mg
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Sotorasib (AMG-510) is a first-in-class, orally bioavailable, and selective KRAS G12C covalent inhibitor. Sotorasib irreversibly inhibits KRAS G12C by locking it in an inactive GDP-bound state. Sotorasib is the first KRAS G12C inhibitor in clinical development and leads to the regression of KRAS G12C tumors.
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Medchemexpress LLC Sant-1 10Mm/1Ml In Dmso | HY-100224
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Sant-1 10Mm/1Ml In Dmso
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Research Products International Corp Staurosporine, 100 Micrograms
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Staurosporine is a potent natural compound and is a crucial tool in studying signal transduction pathways, cell cycle regulation, and cancer therapy. In cell biology, Staurosporine is widely used to investigate cellular processes involving protein kinases. It acts as a broad-spectrum kinase inhibitor, targeting various protein kinases involved in signal transduction, which helps researchers explore complex intracellular signaling networks. This has far-reaching implications for understanding the mechanisms underlying cell growth, differentiation, and apoptosis.
Pharmacologists and pharmaceutical researchers leverage Staurosporine in drug discovery and development. Its ability to inhibit kinases makes it valuable in identifying potential therapeutic targets and assessing the efficacy of novel compounds for treating diseases like cancer. In cancer research.
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Sigma Aldrich Fine Chemicals Biosciences Penicillin G potassium salt ~1600 U/mg | 113-98-4 | MFCD00036193 | 10mu
Penicillin G potassium salt ~1600 U/mg | Mol Wt: 372.48 | 113-98-4 | MFCD00036193 | 10mu
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Alkali Scientific CellPro™ Penicillin, Streptomycin, and Glutamine Solution, 100ml
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Effective against gram negative and gram positive microorganisms. Penicillin interferes with the final stage of synthesis of the bacterial cell wall. Streptomycin inhibits elongation at transpeptidation step during protein synthesis and binds to 30S subunit, causing misreading. Common working concentration for penicillin is 100 U/mL; for Streptomycin: 100 μg/mL. Penicillin/Streptomycin is a broad spectrum bacteriostatic with activity against gram negative and gram-positive organisms. ****This item is required to ship on dry ice. Overnight Shipping required, For Research Use Only (RUO)
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American Radiolabeled Chemicals Inc CILASTATIN NA 50UC
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Cilastatin-3H(G) sodium salt 50uCi in ethanol:water (1:1), 1 mCi/ml, S.A. 5-25 Ci/mmol, M.W. 380.43, Shipped in Dry Ice, Exclusive
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Abcam Tunicamycin, Protein glycosylation inhibitor, 10MG
MW 816.9 Da, Purity >98%. Nucleoside antibiotic that inhibits protein glycosylation. Inhibits GlcNAc phosphotransferase (GPT) and inhibits the transfer of N-acetylglucosamine-1-phosphate from UDP-N-acetylglucosamine to dolichol phosphate in the first step of glycoprotein synthesis. Inhibits N-linked glycosylation and blocks the formation of N-glycosidic protein-carbohydrate linkages. Active in vitro against Gram-positive bacteria, yeasts, fungi and viruses.
The product is subject to the following: Abcam Restricted Use Statement
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Gold Biotechnology Inc Penicillin G Sodium Salt, USP Grade 50 g
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Penicillin G is a β-lactam antibiotic produced by the Penicillium fungus. It has shown efficacy against a variety of Streptococcus species as well as non-penicillinase producing Staphylococcus species.
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Research Products International Corp Ammonium Persulfate [APS], 500 Grams
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Used as a catalyst for acrylamide gel polymerization.
- Heavy Metals: <0.005%
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Research Products International Corp Ampicillin, Sodium Salt, 500 Grams
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Ampicillin, Sodium Salt is a semi-synthetic penicillin antibiotic effective against a broad range of Gram-positive and Gram-negative bacteria. Supplied as a powder, it is commonly used in molecular biology, microbiology, and genetic engineering. It serves as a selective agent in plasmid-based cloning and helps prevent bacterial contamination in cell cultures. By inhibiting bacterial cell wall synthesis, it ensures the purity of cultures and enables selection of Ampicillin-resistant strains. Key features include broad-spectrum activity, DNase/RNase-free quality, and good stability in aqueous solution, allowing for flexible handling.
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Research Products International Corp Puromycin Dihydrochloride, 500 Milligrams
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Puromycin Dihydrochloride is a potent antibiotic. It is an amino nucleoside antibiotic that mimics the 3'-end of aminoacyl-tRNA. It enters the ribosomal A site during translation, causing premature chain termination and inhibiting protein synthesis. Puromycin is incorporated into growing polypeptide chains, leading to the release of incomplete and nonfunctional peptides.
Widely used as a tool in cell biology to study protein synthesis and investigate translation processes. Its ability to terminate protein synthesis at the ribosome makes it valuable for various applications, including pulse-chase experiments and the analysis of nascent peptides. Puromycin resistance genes are often used as selectable markers in genetic engineering. Cells expressing the resistance gene can survive and proliferate in the presence of Puromycin, allowing for the selection of transfected or transduced cells.
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Research Products International Corp PENICILLIN/STREPTOMYCIN/NEOMYCIN MIXTURE, 50ML
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Penicillin, Streptomycin, and Neomycin solution is a common combination antibiotic mixture that inhibits the growth of bacteria. This specific combination creates a broad-spectrum antibiotic effective against a wide range of Gram-positive and Gram-negative bacteria.
This soluion is commonly used in cell culture and microbiology research to prevent bacterial contamination. When added to a cell culture medium, it creates a sterile environment unfavorable for bacterial growth.
WARNING! This product can expose you to Streptomycin sulfate and Neomycin sulfate, chemicals which are known to the State of California to cause developmental harm. For more information go to www.P65Warnings.ca.gov.
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Research Products International Corp Spectinomycin Sulfate, 25 Grams
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Spectinomycin Sulfate is an antibiotic that belongs to the class of aminocyclitol antibiotics and is effective against a variety of Gram-negative bacteria. It is frequently used as a selective agent in genetic engineering and gene expression studies.
Researchers incorporate Spectinomycin Sulfate into growth media to selectively allow the growth of cells or organisms that have been genetically modified to carry a resistance gene for Spectinomycin. This resistance gene enables the cells to survive and reproduce in the presence of Spectinomycin, while non-transformed cells are inhibited.
Spectinomycin Sulfate is known for its effectiveness against certain antibiotic-resistant strains of bacteria, making it a valuable tool in research. It works by interfering with protein synthesis in bacteria, ultimately leading to cell death.
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Research Products International Corp Bacitracin, 1 Grams
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Bacitracin is an antibiotic that has significant importance in the life science marketplace. It is derived from the bacterium Bacillus subtilis and belongs to the class of polypeptide antibiotics.
In the life science marketplace, bacitracin is primarily used for its antimicrobial properties. It is commonly employed in microbiology laboratories, research, and pharmaceutical industries. Bacitracin is effective against a wide range of Gram-positive bacteria, including Staphylococcus and Streptococcus species.
One of the key applications of bacitracin is in cell culture and tissue culture work. It is used as an additive in cell culture media to prevent bacterial contamination, ensuring the growth of uncontaminated cell lines. Bacitracin acts by inhibiting the synthesis of the bacterial cell wall, leading to the disruption of bacterial growth and preventing contamination.
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Research Products International Corp Blasticidin S Hydrochloride Powder, 50 Milligrams
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Blasticidin S hydrochloride powder is a commonly used antibiotic in the life science marketplace. It is primarily employed as a selective agent in cell culture systems and molecular biology applications.
Blasticidin S is derived from Streptomyces griseochromogenes and is effective against a wide range of organisms, including bacteria, yeast, fungi, and certain higher eukaryotic cells. It works by inhibiting protein synthesis in cells, specifically targeting the 80S ribosome and interfering with the peptidyl transferase activity.
In the life science marketplace, Blasticidin S hydrochloride powder is frequently used in cell culture research and genetic engineering. It is added to growth media to select for cells that have successfully incorporated a Blasticidin S resistance gene, typically as part of a recombinant DNA construct or plasmid vector.
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