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Filtered Search Results
Medchemexpress LLC HY-108599 1mg Medchemexpress, DCP-LA CAS:28399-31-7 Purity:>98%
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Medchemexpress, HY-108599 1mg DCP-LA CAS:28399-31-7 DCP-LA (FR236924), a linoleic acid derivative, selectively and directly activates PKCε. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC ILK-IN-3 5mg | 6975-75-3 | 5 MG
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ILK-IN-3 is an orally active small-molecule inhibitor of integrin-linked kinase (ILK) intended for research use. It has formula C10H12N6O and a molecular weight of 232.24 g/mol, and the batch COA reports LCMS purity of 99.62%. It has been reported to enhance the anticancer efficacy of docetaxel in orthotopic LCC6 models.
- Orally active integrin-linked kinase (ILK) inhibitor
- High reported purity (99.62% LCMS)
- Suitable for in vitro and in vivo cancer model studies
- Available in small mg-scale pack sizes for research (e.g., 5 mg)
- Provided as a solid with defined molecular formula and weight
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Medchemexpress LLC HY-100229 10mg Medchemexpress, Aloxistatin CAS:88321-09-9 Purity:>98%
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Medchemexpress, HY-100229 10mg Aloxistatin CAS:88321-09-9 Aloxistatin (E64d) is a cell-permeable and irreversible broad-spectrum cysteine protease inhibitor. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-100619A 10mg Medchemexpress, BMS-986020 (sodium) CAS:1380650-53-2 Purity:>98%
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Medchemexpress, HY-100619A 10mg BMS-986020 (sodium) CAS:1380650-53-2 BMS-986020 sodium is a high-affinity lysophosphatidic acid receptor 1 (LPA1) antagonist. BMS-986020 sodium inhibits bile acid and phospholipid transporters with IC50s of 4.8 µM, 6.2 µM, and 7.5 µM for BSEP, MRP4, and MDR3, respectively. BMS-986020 sodium has the potential for the treatment of idiopathic pulmonary fibrosis (IPF)[3]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-A0082 100mg Medchemexpress, Diphenidol (hydrochloride) Difenidol hydrochloride CAS:3254-89-5 Purity:98%
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Medchemexpress,HY-A0082 100mg Diphenidol (hydrochloride) Difenidol hydrochloride CAS:3254-89-5 Formula:C21H28ClNO Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 103408-45-3 | Pyrimido[1,2-a]purin-10(1H)-one | MFCD03413766 | 250mg
ChemScene | 5-Bromo-4-chloropicolinic acid | 100mg | 569148190 | CS-W018684 | 1060802-25-6 | MFCD13189053 | 236.450 | C6H3BrClNO2
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Medchemexpress LLC Tomatidine hydrochloride | 6192-62-7 | 50 MG
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Tomatidine hydrochloride acts as an anti-inflammatory agent by blocking NF-κB and JNK signaling. It also activates autophagy in mammal cells or C elegans. In vitro, Tomatidine decreases inducible NO synthase and COX-2 expression by suppressing I-κBα phosphorylation, NF-κB nuclear translocation, and JNK activation, which subsequently inhibits c-jun phosphorylation and Oct-2 expression. It causes dose-dependent inhibition of LPS-induced iNOS expression and suppresses the binding activity of NF-κB.
- Acts as an anti-inflammatory agent
- Blocks NF-κB and JNK signaling pathways
- Activates autophagy in mammal cells or C elegans
- Decreases inducible NO synthase and COX-2 expression
- Inhibits I-κBα phosphorylation and NF-κB nuclear translocation
- Suppresses JNK activation and c-jun phosphorylation
- Inhibits LPS-induced iNOS expression
- Suppresses NF-κB binding activity
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Apexbio Technology LLC Trospium chloride 10405-02-4 25mg
Trospium chloride (CAS 10405-02-4) is a quaternary ammonium compound that functions as a competitive antagonist at muscarinic acetylcholine receptors thereby inhibiting cholinergic stimulation of the bladder detrusor muscle This action reduces involuntary bladder contractions leading to decreased urinary urgency frequency and urge incontinence Trospium chloride displays pharmacological properties distinct from tertiary amine antimuscarinics including limited central nervous system penetration It is widely utilized in preclinical and clinical research focused on urinary disorders and muscarinic receptor pharmacology
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Medchemexpress LLC HY-103254 5mg Medchemexpress, ML221 CAS:877636-42-5 Purity:>98%
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Medchemexpress, HY-103254 5mg ML221 CAS:877636-42-5 ML221 is a potent apelin (APJ) functional antagonist, inhibiting apelin-13-mediated activation of APJ, with IC50s of 0.70 μM in the cAMP assay, and 1.75 μM in the β-arrestin assay, and EC80 of 10 nM in both assays. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 1219805-72-7 | Medchem Express | 3-Hydroxyglutaric acid-d5 | 1mg | 736630331 | HY-113411S | 153.145 | C5H8O5
Medchem Express | LY2444296 | 5mg | 515744129 | HY-135230 | 1346133-11-6 | 408.449 | C24H22F2N2O2
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Medchemexpress LLC HY-B0024 100mg Medchemexpress, Prulifloxacin CAS:123447-62-1 Purity:>98%
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Medchemexpress, HY-B0024 100mg Prulifloxacin CAS:123447-62-1 Prulifloxacin (NM441) is an orally active fluoroquinolone antibiotic with a broad spectrum of activity against Gram-positive and -negative bacteria. Prulifloxacin is a prodrug of a thiazeto-quinoline carboxylic acid derivative Ulifloxacin (NM394). Prulifloxacin has the potential for lower urinary tract infections and exacerbations of chronic bronchitis. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Enzo Life Sciences Epoxomicin, (100µg), CAS Number: 134381-21-8
Key inhibitor for use in proteasome research. Formula: C28H50N4O7. MW: 554.7. CAS Number: 134381-21-8. MI: 14: 3630. Purity: ≥95% (HPLC). Appearance: Lyophilized. Very thin transparent film. Solubility: Soluble in DMSO (15mg/ml) or dichloromethane:methanol (9:1); insoluble in water. Use/Stability: Stable for at least 1 year after receipt when stored, as supplied, at -20°C. Stock solutions are stable for up to 3 months at -20°C. Long Term Storage: -20°C
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Research Products International Corp Chlortetracycline Hydrochloride, 25 Grams
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Chlortetracycline Hydrochloride is a tetracycline antibiotic. Chlortetracycline inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, preventing the attachment of aminoacyl-tRNA to the mRNA-ribosome complex. The interference disrupts the translation process and inhibits bacterial growth.
This antibiotic offers a broad spectrum of antibacterial activity against both Gram-positive and Gram-negative bacteria. It also forms complexes with calcium, magnesium, aluminum, and iron, leading to reduced absorption.
Additionally, it is useful to study bacterial susceptibility patterns or as a selective agent in culture media to isolate bacteria that are sensitive to this antibiotic.
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Enzo Life Sciences Aclacinomycin A, (5mg), CAS Number: 57576-44-0
Originally identified as an anti-tumor drug, aclacinomycin A is the first described non-peptidic inhibitor showing discrete specificity for the chymotrypsin-like activity of the 20S proteasome. Aclacinomycin A has no effect on cathepsin B, it stimulates trypsin activity but inhibits the activity of both chymotrypsin and calpain. Alternative Name: Aclarubicin. Formula: C42H53NO15. MW: 811.9. CAS Number: 57576-44-0. Purity: ≥95% (TLC). Appearance: Yellow powder with orange cast. Solubility: Soluble in DMSO (25mg/ml) or dimethyl formamide (25mg/ml). Long Term Storage: -20°C
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Medchemexpress LLC 1-(6,7-dichloro-9-(1-methyl-1H-pyrazol-3-yl)-3,4-dihydro-1H-pyrido[4,3-b]indol-2(5H)-yl)-2-hydroxyethanone | 2369751-07-3 | MFCD34368516 | 99.2% | C17H16Cl2N4O2 | 10MG
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G140 is a small-molecule research inhibitor of cyclic GMP-AMP synthase (cGAS) used to investigate innate immune and inflammatory signaling. It is potent against human cGAS (IC50 14.0 nM) and shows activity against mouse cGAS (IC50 442 nM), and is provided as a high-purity compound for in vitro studies.
- Potent, selective inhibition of cGAS in human assays.
- IC50 14.0 nM for human cGAS and 442 nM for mouse cGAS.
- High purity suitable for biochemical and cell-based assays.
- Supplied as a small-molecule solid for in vitro research.
- Enables study of the cGAS-STING pathway and inflammatory responses.
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