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Filtered Search Results
Medchemexpress LLC Sting agonist-7 | 2767442-46-4 | 97.2% | C17H12N4O4 | 10MG
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STING agonist-7 is a non-nucleotide agonist of the stimulator of interferon genes (STING) pathway used in research to probe STING-mediated immunology and inflammation. It binds selectively to mouse STING but not human STING and has limited cell membrane permeability. The compound is supplied at high purity and is DMSO-soluble for experimental applications.
- Non-nucleotide STING agonist suitable for pathway studies.
- Selective binding to mouse STING with minimal activity on human STING.
- Poor cell membrane permeability, relevant for assay design.
- High purity (~97.2%) for reproducible results.
- Soluble in DMSO (62.5 mg/mL); ultrasonic aid recommended.
- Storage: 4°C protected from light; in solvent store at -80°C (6 months) or -20°C (1 month).
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Medchemexpress LLC Pptn hydrochloride | 1992047-65-0 | 99.89% | 511.96 | 10 MG
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PPTN hydrochloride is a potent, high-affinity, competitive, and highly selective P2Y14 receptor antagonist with a KB value of 434 pM. It shows no agonist or antagonist effect at the P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, or P2Y13 receptors. It also exhibits anti-inflammatory and anti-immune activity.
- Potent, high-affinity, competitive, and highly selective P2Y14 receptor antagonist
- Exhibits no agonist or antagonist effect at P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, or P2Y13 receptors
- Inhibits UDP-glucose-promoted chemotaxis in differentiated HL-60 human promyelocytic leukemia cells with IC50s of ~1 nM (in the presence of 10 μM UDP-glucose) and ~4 nM (in the presence of 100 μM)
- Significantly decreases the ratios of p-ERK1/2 to ERK1/2 and p-p38 to p38 at 10 μM
- Anti-inflammatory activity
- Anti-immune activity
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Medchemexpress LLC Valinomycin | 2001-95-8 | MFCD00005114 | 10 MG
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Valinomycin is a potassium-specific ionophore and cyclic dodecadepsi-peptide antibiotic. Its complex with potassium disrupts the normal K+ gradient across biological bilayer membranes, leading to cell death. This property contributes to its antibiotic, antifungal, antiviral, antitumor, and insecticidal efficacy. Incorporating Valinomycin into liposomes can reduce cytotoxicity and enhance targeting, making it a valuable research tool.
- Potassium-specific ionophore
- Disrupts normal K+ gradient across cell membranes
- Exhibits antibiotic, antifungal, antiviral, antitumor, and insecticidal efficacy
- Can be incorporated into liposomes to reduce cytotoxicity and enhance targeting
- Cyclic dodecadepsi-peptide structure
- Storage Conditions:
- Powder: -80°C for 2 years; -20°C for 1 year (sealed storage, away from moisture)
- In solvent: -80°C for 6 months; -20°C for 1 month (sealed storage, away from moisture)
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Medchemexpress LLC Naftifine hydrochloride | 65473-14-5 | 99.67% | 500 MG
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Naftifine hydrochloride is an antibiotic with antifungal activity against dermatophytes, aspergilli, *Sporothrix schenckii*, and yeasts of the genus *Candida*. It can be used for research into superficial dermatomycoses inhibition, exhibiting activity against various fungal strains in vitro.
- Antibiotic with antifungal activity
- Effective against dermatophytes, aspergilli, *Sporothrix schenckii*, and *Candida* species
- Suitable for research into superficial dermatomycoses inhibition
- High purity of 99.67%
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Medchemexpress LLC Erythromycin estolate | 3521-62-8 | 100 MG
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Erythromycin estolate is a macrolide antibiotic derived from Erythromycin, utilized for treating a broad spectrum of bacterial infections. It has been noted to cause liver injury, often presenting as cholestatic hepatitis, with its toxicity linked to inhibiting bile acid transport. This compound also exhibits antiviral properties by inactivating viral particles and destroying their membrane integrity.
- Used as a macrolide antibiotic.
- Effective against a wide variety of bacterial infections.
- Causes liver injury, predominantly cholestatic hepatitis.
- Toxicity is associated with inhibiting bile acid transport.
- Inactivates viral particles by destroying viral membrane integrity.
- Inhibits various flaviviruses, including Zika, dengue, and yellow fever viruses.
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Teknova 50mg/mL Erythromycin Solution. 25mL in 60mL Bottle, Sterile.
Premade antibiotic solutions are ready-to-use as a supplement for your tissue culture, bacteria media or other specific needs. Antibiotics are often used in cell culture to prevent contamination, maintain aseptic conditions, or select for cells containing genetic modifications.
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Research Products International Corp Ampicillin, Sodium Salt, 5 Grams
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Ampicillin, Sodium Salt is a semi-synthetic penicillin antibiotic effective against a broad range of Gram-positive and Gram-negative bacteria. Supplied as a powder, it is commonly used in molecular biology, microbiology, and genetic engineering. It serves as a selective agent in plasmid-based cloning and helps prevent bacterial contamination in cell cultures. By inhibiting bacterial cell wall synthesis, it ensures the purity of cultures and enables selection of Ampicillin-resistant strains. Key features include broad-spectrum activity, DNase/RNase-free quality, and good stability in aqueous solution, allowing for flexible handling.
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Ambeed D-alpha-Hydroxyglutaric Acid Disodium | 103404-90-6 | MFCD00069573 | 1 g
D-alpha-Hydroxyglutaric Acid Disodium | Purity: 95% | Mol Wt: 192.08 | 103404-90-6 | MFCD00069573 | 1 g
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eMolecules 374703-78-3 | Medchem Express | PKG drug G1 | 5mg | 446260222 | HY-112197 | 257.31 | C13H11N3OS
Medchem Express | Oxyphyllacinol | 5mg | 721434815 | HY-N9633 | 87657-77-0 | 314.425 | C20H26O3
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Medchemexpress LLC Sant-1 | 304909-07-7 | MFCD01827306 | 99.8% | 373.49 g/mol | C23H27N5 | 100 MG
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SANT-1 is a small-molecule antagonist of the Smoothened (Smo) receptor that inhibits Hedgehog signaling. It demonstrates low-nanomolar activity in cell-based assays and is used to probe Smo-mediated signaling in cellular models.
- Potent Smoothened (Smo) antagonist with low-nanomolar IC50s (20 nM and 30 nM).
- Reduces proliferation of medulloblastoma cells at 1 μM.
- High purity (~99.8%) suitable for research applications.
- Soluble in DMSO (25 mg/mL) with documented in vivo formulation protocols.
- Powder stable at -20°C for extended storage.
- Available in multiple package sizes up to 500 mg.
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Medchemexpress LLC L-alpha-amino-beta-ureidopropionic acid | 1483-07-4 | >98.0% | 10 MG
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L-albizziin is an amino acid analogue used as a glutaminase inhibitor in biochemical and cancer research. It has molecular formula C4H9N3O3 and a molecular weight of 147.13 g/mol.
- Glutaminase inhibitor for research use.
- Amino acid analogue suitable for biochemical assays.
- Cas number 1483-07-4.
- Molecular formula C4H9N3O3 and molecular weight 147.13 g/mol.
- Recommended storage: powder at -20°C (long term) or 4°C; in solvent store at -80°C for short term.
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Medchemexpress LLC Mozavaptan hydrochloride | 138470-70-9 | MFCD11111965 | 99.9% | 464.00 | C27H30ClN3O2 | 100MG
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Mozavaptan hydrochloride is a benzazepine-derived, selective vasopressin V2 receptor antagonist supplied as the hydrochloride salt for research applications. It antagonizes arginine vasopressin's antidiuretic action and is commonly used to model and study disorders of water balance such as hyponatremia and SIADH. The material is provided with specified purity and recommended storage conditions for laboratory use.
- Potent V2 receptor antagonist (IC50 ≈ 14 nM).
- Approximately 85-fold selectivity for V2 over V1 receptor.
- High purity for research use (99.89%).
- Available in multiple pack sizes, including 100 mg.
- Stable when stored sealed at 4°C; in solvent: -80°C (6 months) or -20°C (1 month).
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Medchemexpress LLC Furafylline | 80288-49-9 | 260.25 g·mol⁻1 | C12H12N4O3 | 10 MG
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Furafylline is a research-grade, selective inhibitor of human cytochrome P450 1A2 (CYP1A2) commonly used in in vitro studies of drug metabolism and enzyme mechanism. It is typically provided as a solid for dissolution in solvents such as DMSO and is intended for research use only.
- Selective inhibitor of CYP1A2 with an IC50 of 0.07 μM.
- Suitable for in vitro inhibition and drug-drug interaction studies.
- Molecular formula C12H12N4O3; molecular weight 260.25 g·mol⁻1.
- Powder storage at -20°C; in solvent storage at -80°C for long term.
- Provided as an analytical-grade solid for research applications.
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Medchemexpress LLC Urea, N-[2-chloro-7-[(3S,5S)-3,5-dimethyl-4-morpholinyl]pyrazolo[1,5-a]pyrimidin-6-yl]-... | 2682102-10-7 | 99.6% | 469.85 | C19H19ClF3N7O2 | 5 MG
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MLT-231 is a potent, highly selective allosteric inhibitor of MALT1 intended for research use. It inhibits MALT1 enzymatic activity with IC50 ≈ 9 nM, prevents endogenous BCL10 cleavage (IC50 ≈ 160 nM), and has demonstrated antitumor activity in ABC-DLBCL xenograft models.
- Potent allosteric inhibition of MALT1 with low-nanomolar activity.
- Prevents BCL10 cleavage in cellular assays, supporting mechanism studies.
- Demonstrated antitumor activity in preclinical xenograft models.
- Available as solid and as DMSO solution for assay flexibility.
- High chemical purity for reproducible experimental results.
- Recommended storage conditions support long-term stability.
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Apexbio Technology LLC Rifapentine, 50mg. Cas: 61379-65-5 MFCD: MFCD00866806. antibiotic drug used in the treatment of tuberculosis
Rifapentine (Priftin) is an antibiotic compound used in the treatment of tuberculosis. 61379-65-5. MFCD00866806
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