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Filtered Search Results
eMolecules (S)-2-(1-((9H-Purin-6-yl)amino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one | 870281-82-6 | MFCD19443647 | 1g
Combi-Blocks | (S)-2-(1-((9H-Purin-6-yl)amino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one | 1g | 401040531 | QD-4765 | 98.000 | 870281-82-6 | MFCD19443647 | 415.432 | C22H18FN7O
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Apexbio Technology LLC Geldanamycin 30562-34-6 100mg
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Geldanamycin is an antibiotic from Streptomyces hygroscopicus that inhibits heat shock protein 90 (Hsp90) by binding to its ATP-binding pocket This disruption affects protein folding and stabilization impacting cell proliferation stress response and tumor biology Geldanamycin is used as a molecular tool in these studies and has activity against various microbes including bacteria fungi protozoa and nematodes IC50 values range from nanomolar to micromolar levels depending on the cell line and conditions It is also applied in research on vascular relaxation glucocorticoid receptor modulation and inflammation-related signaling pathways
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Research Products International Corp Puromycin Dihydrochloride, 100 Milligrams
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Puromycin Dihydrochloride is a potent antibiotic. It is an amino nucleoside antibiotic that mimics the 3'-end of aminoacyl-tRNA. It enters the ribosomal A site during translation, causing premature chain termination and inhibiting protein synthesis. Puromycin is incorporated into growing polypeptide chains, leading to the release of incomplete and nonfunctional peptides.
Widely used as a tool in cell biology to study protein synthesis and investigate translation processes. Its ability to terminate protein synthesis at the ribosome makes it valuable for various applications, including pulse-chase experiments and the analysis of nascent peptides. Puromycin resistance genes are often used as selectable markers in genetic engineering. Cells expressing the resistance gene can survive and proliferate in the presence of Puromycin, allowing for the selection of transfected or transduced cells.
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eMolecules Medchem Express / ()-Huperzine A / 5mg / 446268309 / HY-17388 / / 120786-18-7 / MFCD00867726 / 242.322 / C15H18N2O
Medchem Express / ()-Huperzine A / 5mg / 446268309 / HY-17388 / / 120786-18-7 / MFCD00867726 / 242.322 / C15H18N2O
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Medchemexpress LLC Butanedioic acid, compd. with cabamiquine (6-fluoro quinoline carboxamide) | 2444781-71-7 | 99.8% | 580.65 | C31H37FN4O6 | 10 MG
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Cabamiquine succinate is the succinate salt of cabamiquine (DDD107498), a potent orally active antimalarial research compound that inhibits Plasmodium protein synthesis via eEF2/CaMKIII. It is supplied as a white to off-white solid with high analytical purity and intended for laboratory research.
- High purity: 99.8% (LCMS).
- Suitable for in vitro and preclinical assays targeting Plasmodium species.
- Soluble in DMSO (≈135 mg/mL); ultrasonic agitation may be required.
- Storage: sealed, away from moisture and light; in solvent store -80°C (6 months) or -20°C (1 month).
- Available in small mg-scale packages for research applications.
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Research Products International Corp RPI Anisomycin from streptomyces griseolus [2-[(4-Methoxyphenyl)methyl]-3, 4-pyrrolidinediol-3-acetate], 500 Milligrams
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Anisomycin is an antibiotic derived from Streptomyces griseolus. It inhibits protein synthesis in eukaryotic cells by blocking the peptidyl transferase activity of the 60S ribosomal subunit. This interference disrupts the elongation phase of protein synthesis, leading to the inhibition of new protein formation.
Anisomycin is widely used as a tool in cell biology and biochemistry to study cellular responses to stress, apoptosis, and various signaling pathways. Its ability to selectively inhibit protein synthesis allows researchers to investigate the role of specific proteins in cellular processes. Anisomycin induces cellular stress and activates various stress response pathways, making it valuable in studies focused on understanding how cells respond to environmental challenges.
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eMolecules Sulfisomidine | 515-64-0 | 5G | Purity: 95%
Combi-Blocks | Sulfisomidine | 5G | 515-64-0 | MFCD00010567
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Medchemexpress LLC HY-16289 5mg Medchemexpress, Lodoxamide (tromethamine) CAS:63610-09-3 Purity:>98%
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Medchemexpress, HY-16289 5mg Lodoxamide (tromethamine) CAS:63610-09-3 Lodoxamide tromethamine (U-42585E) is a medication for the treatment of prophylaxis of mast cell-mediated allergic disease. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC 2-[[1-(cyclopropylmethoxy)-4-hydroxy-2-oxoquinoline-3-carbonyl]amino]acetic acid | 1616690-16-4 | 99.1% | 332.31 g/mol | C16H16N2O6 | 25 MG
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Desidustat is an orally active hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitor used in research to stimulate erythropoiesis and to study anemia and ischemia/hypoxia-related conditions. The compound is supplied in solid and solution formats and is characterized by high purity and defined molecular properties.
- Orally active HIF prolyl hydroxylase inhibitor for research use.
- Used to model anemia and hypoxia/ischemia-related conditions.
- High reported purity (99.1%).
- Molecular formula C16H16N2O6; molecular weight 332.31 g/mol.
- Available as small solid packs and DMSO solutions for assay preparation.
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Medchemexpress LLC 9-oxo-9H-indeno [1,2-b]pyrazine-2,3-dicarbonitrile | 924296-17-3 | 99.0% | 287.28 g·mol⁻¹ | C16H9N5O | 10 MG
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DUB-IN-3 is a small-molecule deubiquitinase inhibitor reported to selectively inhibit USP8 and used in biochemical and cell-based research. Supplied as a light yellow solid with reported purity ≥99% and molecular weight 287.28 g·mol⁻¹, it is intended for research use only.
- Potent USP8 inhibitor with reported IC50 ≈ 0.56 μM.
- High purity suitable for research applications.
- Available as a 10 mg solid and in larger pack sizes or solution forms.
- Light yellow to yellow solid with defined storage conditions for powder and solution.
- Documented CAS number and molecular formula for unambiguous identification.
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Medchemexpress LLC Rapamycin | 53123-88-9 | MFCD00867594 | 99.0% | 914.2 g/mol | C51H79NO13 | 100 MG
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Rapamycin (sirolimus) analytical standard intended for research and analytical applications. Supplied as a 100 mg reference material for assay, calibration, and method development.
- Analytical standard of rapamycin for research and analytical use.
- CAS number 53123-88-9.
- Molecular formula C51H79NO13 and molecular weight 914.2 g/mol.
- Purity 98.98% (as listed by the manufacturer).
- Suitable for assay, calibration, and method validation.
- Synonyms include sirolimus and AY-22989.
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eMolecules Medchem Express / THZ1 (Hydrochloride) / 5mg / 446271628 / HY-80013A / / / MFCD28167786 / 602.520 / C31H29Cl2N7O2
Medchem Express / THZ1 (Hydrochloride) / 5mg / 446271628 / HY-80013A / / / MFCD28167786 / 602.520 / C31H29Cl2N7O2
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Research Products International Corp Bleomycin Sulfate, 15 Milligrams
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Bleomycin sulfate is an antibiotic derived from Streptomyces verticillus. It has found application in the field of cancer research and treatment. This antibiotic is a glycopeptide with DNA-cleaving properties. It is known for its ability to induce DNA strand breaks, making it effective in inhibiting the replication of cancer cells.
In research settings, bleomycin sulfate is utilized as a tool to study DNA damage and repair mechanisms. It is commonly employed in cell biology experiments to induce controlled DNA damage for the investigation of cellular responses and signaling pathways associated with DNA repair.
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eMolecules Medchem Express / 1A-116 / 5mg / 446258536 / HY-104064 / / 1430208-73-3 / [null] / 307.320 / C16H16F3N3
Medchem Express / 1A-116 / 5mg / 446258536 / HY-104064 / / 1430208-73-3 / [null] / 307.320 / C16H16F3N3
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Medchemexpress LLC Ipatasertib-NH2 | 1001382-14-4 | 99.6% | 50 MG
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Ipatasertib-NH2, also known as GDC-0068-NH2 or RG7440-NH2, functions as a ligand for the target protein AKT within PROTAC (INY-03-041). This PROTAC molecule is specifically designed by combining Ipatasertib-NH2 with a ten-hydrocarbon linker and a CRBN ligand, Lenalidomide, to facilitate E3 ubiquitin ligase activity.
- Purity of 99.6%
- Molecular weight of 415.92
- Chemical formula C21H26ClN5O2
- Appearance as a white to light yellow solid
- Soluble in DMSO at 100 mg/mL
- Recommended storage for powder: -20°C for 3 years, 4°C for 2 years
- Recommended storage in solvent: -80°C for 6 months, -20°C for 1 month
- Ligand for target protein AKT in PROTAC research
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