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Filtered Search Results
Cayman Chemical 1a1bdIhomoProstaglndInE11mg
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PGE1 is not a major naturally occurring PG, but is widely administered clinically for several indications including peripheral occlusive vascular disease, erectile dysfunction, and in neonatal cardiology.{22,3803} COX metabolism of the unusual fatty acid 10,13,16-docosatrienoic acid yields 1a,1b-dihomo PGE1. This rare metabolite has been recovered from incubations of whole sheep seminal vesicles, but has not been reported in humans.{11211} In ex vivo preparations of rat aorta and rat PRP, 1a,1b-dihomo PGE1 was found to be much less active than PGE1 itself.{11212}
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Biolegend Spark PLUS B550TM anti-human C
Spark PLUS B550™ anti-human CD107a (LAMP-1) [H4A3]; Isotype: Mouse IgG1, κ; Reactivity: Human; Apps: FC; Size: 100 tests
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Cayman Chemical 1H 1H 2H 2H-Perfluorodecanesu
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A polyfluoroalkyl substance; has been found as a contaminant in sea and river water
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Cayman Chemical DomIphenbromIde 50g
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A quaternary ammonium-containing cationic surfactant with antimicrobial activity; active against A. viscosus, A. naeslundii, S. mutans, E. coli, and L. monocytogenes bacteria; inhibits C. neoformans yeast growth and spore germination; inhibits the hERG channel (IC50 = 1.5 μM in a whole-cell patch-clamp assay)
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Cayman Chemical PefloxacInmesylate hydrate 25g
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A broad-spectrum and synthetic fluoroquinolone antibiotic; active against clinical isolates of E. coli, K. pneumoniae, S. aureus, and G. vaginalis (MIC90s = 0.12, 0.5, 0.5, and 32 mg/L, respectively) selectively inhibits E. coli topoisomerase I and DNA gyrase over calf thymus topoisomerase I (IC50s = 45, 4.5, and >140 μg/ml, respectively) in cell-free assays; active against systemic E. coli, K. pneumoniae, and P. aeruginosa infections in mice (P50s = 6.5, 29.2, and 219 mg/kg, respectively)
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Cayman Chemical Desloratadine 1g
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A histamine H1 receptor antagonist (Ki = 0.97 nM) and an active metabolite of loratadine; inhibits calcium flow in neurons and glia in vitro (IC50s = 9.177 and 0.3185 µM, respectively) in a 5-HT2A receptor-dependent manner; reduces ovalbumin-induced sneezing, nose rubbing, eye watering, and congestion in ovalbumin-sensitized guinea pigs at 10 mg/kg; increases the clearance of amyloid-β by microglia and reverses learning and memory deficits in the Morris water maze in the APP/PS1 mouse model of Alzheimer’s disease at 20 mg/kg per day
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Biolegend Brilliant Violet 421 anti-human TCR V 13 1 [H131] Isotype Mouse IgG2b Reactivity Human Apps FC Size 25 tests
Brilliant Violet 421 anti-human TCR V 13 1 [H131] Isotype Mouse IgG2b Reactivity Human Apps FC Size 25 tests
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Cayman Chemical IsoquInolIn3carboxylIc AcI 25g
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A synthetic intermediate that has been used to design novel antitumor compounds
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Cayman Chemical THUNDRPhosphop70 S6KT38 2400
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Sandwich TR-FRET immunoassay for semi-quantitative detection of Phospho-p70 S6K (T389) in cell lysates
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Cayman Chemical ProstaglndIn TrnsporterC- 1ea
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Antigen: human PGT C-terminal amino acids 627-640 • Host: rabbit • Cross Reactivity: (+) human, mouse, rat, cow, and sheep PGT; expected to react with canine and chicken PGT • Application(s): ICC, IF, and WB • Transport of extracellular prostaglandins into cells occurs via a specific PG transporter (PGT).
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ABclonal Technology PNLIPRP2 Rabbit pAb
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This gene encodes a lipase that hydrolyzes galactolipids, the main components of plant membrane lipids. An allelic polymorphism in this gene results in both coding and non-coding variants, the reference genome represents the non-coding allele.
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Cayman Chemical 5-IodourIdIn 5g
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A pyrimidine nucleoside derivative; inhibits dihydroorotase (Ki = 340 µM for the rat enzyme); sensitizes Don Chinese hamster lung cells to irradiation; has been used in the synthesis of compounds with antiviral and anticancer activities
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ABclonal Technology SLC5A1 Rabbit pAb
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This gene encodes a member of the sodium-dependent glucose transporter (SGLT) family. The encoded integral membrane protein is the primary mediator of dietary glucose and galactose uptake from the intestinal lumen. Mutations in this gene have been associated with glucose-galactose malabsorption. Multiple transcript variants encoding different isoforms have been found for this gene.
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ABclonal Technology 488 anti-Human CD263/TRAIL-R3
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The protein encoded by this gene is a member of the TNF-receptor superfamily This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain but no cytoplasmic death domain This receptor is not capable of inducing apoptosis and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis This gene was found to be a p53-regulated DNA damage-inducible gene The expression of this gene was detected in many normal tissues but not in most cancer cell lines which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL
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Cayman Chemical DLerythrothreoIsocItrIc Ac 10g
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A mixture of isocitric acid isomers
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