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Filtered Search Results
Cayman Chemical 2,3-MDA (hydrochloride), Purity: ≥98%, CAS: 86029-48-3, 50 mg
A structural homolog of MDA which differs only in the placement of the methyledioxy group; intended for forensic and research applications
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Cayman Chemical 1,2,3-Tripalmitoyl-d31 Glycerol, Purity: ≥99% deuterated forms (d1-d93), CAS: 241157-04-0, 50 mg
An internal standard for the quantification of 1,2,3-tripalmitoyl glycerol by GC- or LC-MS
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Cayman Chemical Norcantharidin, Purity: ≥95%, CAS: 29745-04-8, 1 g
A PP1 and PP2A inhibitor (IC50s = 9 and 3 µM, respectively); induces cell cycle arrest at the G2/M phase and apoptosis in HepG2, Hep3B, and Huh7 human hepatoma cell lines at 5 µg/ml; reduces angiogenesis in a chick chorioallantoic membrane assay at 500-5,000 µg/ml; inhibits growth in a panel of nine human cancer cell lines (GI50s = 30-64 µM); reduces tumor growth in a GBC-SD mouse xenograft model at 28 mg/kg
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Cayman Chemical Cefadroxil (hydrate), Purity: ≥98%, CAS: 66592-87-8, 1 g
A semisynthetic cephalosporin antibiotic; active against B. anthracis, V. cholerae, and P. multocida strains (MICs = 1, 2, and 4 µg/ml, respectively), among others; protective against infection by strains of S. pyogenes, S. pneumoniae, or S. aureus in mice (PD50s = 0.6-2.4, 18-24, and 0.3-29 mg/kg, respectively)
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Cayman Chemical Prochlorperazine (maleate), Purity: ≥98%, CAS: 84-02-6, 250 mg
A dopamine D2 receptor antagonist; binds to rat recombinant D2 receptors (Ki = 4.7 nM); binds to D2 in rat striatal membranes (Ki = 2.9 nM); binds to rat recombinant D3 receptors (Ki = 35 nM); binds to the 5-HT3 receptor in N1E-115 mouse neuroblastoma cell membranes (Ki = 1.2 μM); increases the latency to paw licking in a hot plate test at 2 mg/kg, indicating analgesia; inhibits apomorphine-induced emesis in dogs (ED50 = 0.34 mg/kg)
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CPC Scientific H-Pro-Phe-Thr-Arg-Asn-Tyr-Tyr-Val-Arg-Ala-Val-Leu-His-Leu-OH (trifluoroacetate salt) 5MG
ONE-LETTER SEQUENCE: PFTRNYYVRAVLHLMOLECULAR FORMULA: C83H125N23O19MOLECULAR WEIGHT:1749.1STORAGE CONDITIONS: -20 5CRESEARCH AREA: CancerREFERENCES: M.-Y.Park et al., Biochem. Biophys. Res. Commun. , 204, 924 (1994)
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Cayman Chemical L-Tetrahydropalmatine, Purity: ≥98%, CAS: 483-14-7, 25 mg
An alkaloid that antagonizes the supraspinal dopamine 2 receptor and reduces stress-induced anxiety in rats
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Cayman Chemical Methyl Gallate, Purity: ≥98%, CAS: 99-24-1, 100 g
A phenol with diverse biological activities; reduces adipogenic hormonal stimulation-induced lipid accumulation in 3T3-L1 cells at 50 µM; active against V. cholerae in vitro (MIC = 32 µg/ml) and reduces V. cholerae-induced intestinal fluid accumulation in suckling mice at 50, 100, and 200 mg/kg; reduces tumor growth and decreases the number of intratumor CD25+Foxp3high Tregs in an EL-4 model of murine lymphoma; reduces knee joint edema and leukocyte, neutrophil, and mononuclear cell infiltration in a mouse model of zymosan-induced arthritis at 0.7, 7, and 70 mg/kg
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Cayman Chemical Fosfomycin (calcium salt), Purity: ≥95%, CAS: 26016-98-8, 1 g
A broad-spectrum antibiotic; active against Salmonella and P. aeruginosa at 1.56 and 6.25 µg/ml, respectively, as well as MSSA, cephalosporin- and penicillin-resistant S. pneumoniae, MRSA, and vancomycin-resistant Enterococcus
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Cayman Chemical Dihydrojasmonic Acid, Purity: ≥95% (mixture of isomers), CAS: 3572-64-3, 250 mg
A plant growth regulator; inhibits lettuce seed germination and reduces the radicle length of germinated seedlings at 10 mM
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Cayman Chemical 7-(Diethylamino)coumarin-3-carboxylic Acid, Purity: ≥95%, CAS: 50995-74-9, 100 mg
A fluorescent probe; has been used as a FRET acceptor conjugated to neomycin B or tobramycin for use in the analysis of bacterial RNA binding; has been used as a reactive probe for the derivatization of sulfonamides for LIF detection; ex/em = 407/472 nm, respectively
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Cayman Chemical Erlotinib (hydrochloride), Purity: ≥98%, CAS: 183319-69-9, 500 mg
An EGFR inhibitor (Ki = 2.7 nM); selective for EGFR over Src and Abl at 0.1 µM; induces caspase-3 and -7 activity in NCI H358 cells at 1 µM; reduces EGFR autophosphorylation in an HN-5 mouse xenograft model at 25 mg/kg
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Cayman Chemical Anethole Trithione, Purity: ≥98%, CAS: 532-11-6, 10 g
A dithiolthione with diverse biological activities; selectively binds to α-ARs over β-ARs and mAChRs in isolated rat parotid acini (IC50s = 16.7, >100, and >100 µM, respectively); enhances saliva secretion induced by pilocarpine or electrical stimulation of the parasympathetic nerve in rats; reduces tumor incidence and multiplicity in a rat model of azoxymethane-induced colon adenocarcinoma at 100 and 200 ppm in the diet; prevents decreases in hepatic GSH levels and decreases mortality in mouse models of acetaminophen- or carbon tetrachloride-induced hepatotoxicity at 500 mg/kg
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Cayman Chemical 2-keto D-Gluconic Acid (calcium salt), Purity: ≥95%, CAS: 3470-37-9, 10 g
A bacterial metabolite and precursor in the synthesis of D-erythorbic acid
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Cayman Chemical Trifluoroacetyl Tripeptide-2 (acetate), Purity: ≥98%, 250 mg
A peptide inhibitor of pancreatic and neutrophil elastases (Kis = 0.00056 and 0.5 mM, respectively)
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